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Muscular Dystrophy

    By: Tami Scott
         2013
Muscular Dystrophy Facts

• Muscular Dystrophy (MD) is a genetic disorder that
  causes weakness in the muscles that allow your body
  to move.
• MD can be diagnosed via muscular biopsy.
• MD refers to a group of genetic or hereditary
  disorders that destroy the muscles
• MD varies from the age of onset, the muscles that
  initially attack and the rate of progression.
• Specific symptoms include: wasting of muscles, poor
  balance, pain in the calves, limited range of
  movement, joint contractures, and vision problems.
Individuals with MD do not
    produce Dystrophin
Dystrophin
• Dystrophin deficiency has been
  definitively established as one of the root
  causes of the general class of myopathies
  collectively referred to as muscular
  dystrophy. The large cytosolic protein was
  first identified in 1987 by Louis M. Kunkel,
  after the 1986 discovery of the mutated
  gene that causes Duchenne muscular
  dystrophy (DMD).
There are several types of Muscular Dystrophy

 Duchenne muscular dystrophy
 Becker muscular dystrophy
 Emery-Dreifuss muscular dystrophy
 Limb-girdle muscular dystrophy
 Facioscapulohumeral muscular dystrophy
 Mytonic dystrophy
 Congenital muscular dystrophy
Living with Duchenne’s
Duchenne’s
 Duchenne   muscular dystrophy (DMD) is
 the most common type and is caused
 by a defect with the gene that makes a
 protein called dystrophin. Without the
 protein, the muscles break down and a
 person gradually becomes weaker.
DMD
DMD affects boys and usually begins
somewhere between ages 2-6. By age 10-12,
kids often need to use a wheelchair. The heart
may also be affected, so they need to be
monitored closely by a cardio-pulmonary
specialist. They can also develop curvature of the
spine and tightness in their joints.
Unfortunately, over time, the muscles that
control their breathing become weaker and
they may need a ventilator to breathe. People
with this type of MD usually do not survive
beyond their late teens or early adulthood.
This graph shows the total number of publications written about “Mucsular
    Dystrophy, Duchenne” by year, and weather “Muscular Dystrophy,
 Duchenne” was a major or minor topic of these publications. Publications
                    written by people in UCS Profiles.
Links to
 Muscular Dystrophy Resources

http://profiles.ucsf.edu/display/349973

http;//mda.org/

www.helpful-health.com/diseases/muscular-dystrophy
References
Mickey Lieberman uses his diverse medical background
and experience to research helpful health information on
numerous diseases and illnesses and provides useful resources
for over 100 different medical conditions.


Citation: Disabled World News (2009-02-27) - Muscular
Dystrophy is not just one disease the term refers to a group of
genetic or hereditary disorders that destroy the muscles:
A Life Worth Living!


     References

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Muscular Dustropy

  • 1. Muscular Dystrophy By: Tami Scott 2013
  • 2. Muscular Dystrophy Facts • Muscular Dystrophy (MD) is a genetic disorder that causes weakness in the muscles that allow your body to move. • MD can be diagnosed via muscular biopsy. • MD refers to a group of genetic or hereditary disorders that destroy the muscles • MD varies from the age of onset, the muscles that initially attack and the rate of progression. • Specific symptoms include: wasting of muscles, poor balance, pain in the calves, limited range of movement, joint contractures, and vision problems.
  • 3. Individuals with MD do not produce Dystrophin
  • 4. Dystrophin • Dystrophin deficiency has been definitively established as one of the root causes of the general class of myopathies collectively referred to as muscular dystrophy. The large cytosolic protein was first identified in 1987 by Louis M. Kunkel, after the 1986 discovery of the mutated gene that causes Duchenne muscular dystrophy (DMD).
  • 5. There are several types of Muscular Dystrophy Duchenne muscular dystrophy Becker muscular dystrophy Emery-Dreifuss muscular dystrophy Limb-girdle muscular dystrophy Facioscapulohumeral muscular dystrophy Mytonic dystrophy Congenital muscular dystrophy
  • 7. Duchenne’s  Duchenne muscular dystrophy (DMD) is the most common type and is caused by a defect with the gene that makes a protein called dystrophin. Without the protein, the muscles break down and a person gradually becomes weaker.
  • 8. DMD DMD affects boys and usually begins somewhere between ages 2-6. By age 10-12, kids often need to use a wheelchair. The heart may also be affected, so they need to be monitored closely by a cardio-pulmonary specialist. They can also develop curvature of the spine and tightness in their joints. Unfortunately, over time, the muscles that control their breathing become weaker and they may need a ventilator to breathe. People with this type of MD usually do not survive beyond their late teens or early adulthood.
  • 9. This graph shows the total number of publications written about “Mucsular Dystrophy, Duchenne” by year, and weather “Muscular Dystrophy, Duchenne” was a major or minor topic of these publications. Publications written by people in UCS Profiles.
  • 10. Links to Muscular Dystrophy Resources http://profiles.ucsf.edu/display/349973 http;//mda.org/ www.helpful-health.com/diseases/muscular-dystrophy
  • 11. References Mickey Lieberman uses his diverse medical background and experience to research helpful health information on numerous diseases and illnesses and provides useful resources for over 100 different medical conditions. Citation: Disabled World News (2009-02-27) - Muscular Dystrophy is not just one disease the term refers to a group of genetic or hereditary disorders that destroy the muscles:
  • 12. A Life Worth Living! References

Hinweis der Redaktion

  1. www.helpful-health.com/diseases/muscular-dystrophy