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                                 NanoTechnology




    ABSTRACT
   A nanometer is one billionth of a meter. If you blew up a baseball to the size of the
   earth, the atoms would become visible, about the size of grapes. Some 3- 4 atoms fit
   lined up inside a nanometer. Nanotechnology is about building things atom by atom,
   molecule by molecule. The trick is to be able to manipulate atoms individually, and
   place them where you wish on a structure.

   Nanotechnology uses well known physical properties of atoms and molecules to make
   novel devices with extraordinary properties. The anticipated pay off for mastering this
   technology is beyond any human accomplishment thus far.

   Nature uses molecular machines to create life.Scientists from several fields including
   chemistry, biology, physics, and electronics are driving towards the precise
   manipulation of matter on the atomic scale. How do we get to nanotechnology? Several
   approaches seem feasible. Ultimately a combination may be the key.

   The goal of early nanotechnology is to produce the first nano-sized robot arm capable
   of manipulating atoms and molecules into a useful product or copies of itself.
   Nanotechnology finds applications as nanotubes, in nanomedicine and so on.Soon you
   have trillions of assemblers controlled by nano super computers working in parallel
   assembling objects quickly.
101seminartopics.com

   Ultimately, with atomic precision, everything could be made. It's all a matter of
   software.




  CONTENTS


  * INTRODUCTION
  * NANOTECHNOLOGY
               -AN INTERDISCIPLINARY SUBJECT

  * BOTTOM-UP TECHNOLOGY
  * NANOMACHINES
  * FABRICATION
  * STEWART PLATFORM
  * VISUAL IMAGES IN NANO TECNOLOGY
  * APPLICATIONS
101seminartopics.com


   * CHALLENGES
   * ETHICAL ISSUES
   * CONCLUSION
   * BIBLIOGRAPHY




INTRODUCTION
  A nanometer is one billionth of a meter. That's a thousand, million times smaller than a meter. If
you blew up a baseball to the size of the earth, the atoms would become visible, about the size of
grapes. Some 3- 4 atoms fit lined up inside a nanometer. Nanotechnology is about building things
atom-by-atom, molecule-by-molecule. The trick is to be able to manipulate atoms individually, and
place them where you wish on a structure. Thus nanotechnology can be defined as:

โ€œThorough, inexpensive control of the structure of matter based on molecule-by-molecule
control of products and byproducts; the products and processes of molecular manufacturing. โ€œ

LEARNING FROM NATURE
Technology-as-we-know-it is a product of industry, of manufacturing and chemical
engineering. Industry-as-we-know-it takes things from natureโ€”ore from mountains, trees
from forestsโ€”and coerces them into forms that someone considers useful. Trees become
lumber, then houses. Mountains become rubble, then molten iron, then steel, then cars. Sand
becomes a purified gas, then silicon, and then chips. And so it goes. Each process is crude,
based on cutting, stirring, baking, spraying, etching, grinding, and the like.

Trees, though, are not crude: To make wood and leaves, they neither cut, grind, stir, bake,
spray, etch, nor grind. Instead, they gather solar energy using molecular electronic devices,
the photosynthetic reaction centers of chloroplasts. They use that energy to drive molecular
machinesโ€”active devices with moving parts of precise, molecular structureโ€”which process
carbon dioxide and water into oxygen and molecular building blocks. They use other
101seminartopics.com

molecular machines to join these molecular building blocks to form roots, trunks, branches,
twigs, solar collectors, and more molecular machinery. Every tree makes leaves, and each
leaf is more sophisticated than a spacecraft, more finely patterned than the latest chip from
Silicon Valley. They do all this without noise, heat, toxic fumes, or human labor, and they
consume pollutants as they go. Viewed this way, trees are high technology. Chips and
rockets aren't.

Trees give a hint of what molecular nanotechnology will be like, but nanotechnology won't
be biotechnology. Like biotechnologyโ€”or ordinary treesโ€”molecular nanotechnology will
use molecular machinery, but unlike biotechnology, it will not rely on genetic meddling.




THE SCALE

We humans are huge creations with no direct experience of the molecular world, and this can
make nanotechnology hard to visualize, hence hard to understand. The nano in
nanotechnology comes from nanos, the Greek word for dwarf. In science, the prefix nano-
means one-billionth of something, as in nanometer and nanosecond, which are typical units
of size and time in the world of molecular manufacturing. Lets try to visualize: you say,
"Shrink me!", and the world seems to expand.



                                                        Frame (A) shows a hand holding a computer chip. This
                                                        is shown magnified 100 times in (B). Another factor of
                                                        100 magnification (C) shows a living cell placed on the
                                                        chip to show scale. Yet another factor of 100
                                                        magnification (D) shows two nanocomputers beside the
                                                        cell. The smaller (shown as block) has roughly the same
                                                        power as the chip seen in the first view; the larger (with
                                                        only the corner visible) is as powerful as mid-1980s
                                                        mainframe computer. Another factor of 100
                                                        magnification (E) shows an irregular protein from the cell
                                                        on the lower right, and a cylindrical gear made by
                                                        molecular manufacturing at top left. Taking a smaller
                                                        factor of 10 jump, (F) shows two atoms in the protein,
                                                        with electron clouds represented by stippling. A final
                                                        factor of 100 magnification (G) reveals the nucleus of
                                                        the atom as a tiny speck.
101seminartopics.com

NANOTECHNOLOGY-AS AN INTERDISCIPLINARY SUBJECT
Another feature of nanotechnology is that it is the one area of research and development that
is truly multidisciplinary. Research at the nanoscale is unified by the need to share
knowledge on tools and techniques, as well as information on the physics affecting atomic
and molecular interactions in this new realm. Materials scientists, mechanical and electronic
engineers and medical researchers are now forming teams with biologists, physicists and
chemists
TOP-DOWN                                             BOTTOM-UP

'Top-down' refers to making nano scale structures    'Bottom-up', or molecular nanotechnology,
by machining and etching techniques.                 applies to building organic and inorganic
                                                     structures atom-by-atom, or molecule-by-
                                                     molecule.
Microscopic irregularities will always be present.
                                                     Atomic scale manufacturing is devoid of all
                                                     possible irregularities.
Bonds cannot be manipulated. Thus new materials
cannot be formed.
                                                     Manipulation of bonds enables creation of new
Eg. Silicon crystal๏ƒ  sliced๏ƒ required atomic          materials with desired properties.
scale silicon wafer obtained.
                                                     Eg. Silicon atoms๏ƒ  assembled by suitable
                                                     techniques๏ƒ  required atomic scale silicon wafer
                                                     obtained.



BOTTOM-UP TECHNOLOGY

The two fundamentally different approaches to nanotechnology are graphically termed 'top
down' and 'bottom up'. 'Top-down' refers to making nanoscale structures by machining and
etching techniques, whereas 'bottom-up', or molecular nanotechnology, applies to building
organic and inorganic structures atom-by-atom, or molecule-by-molecule. Top-down or
bottom-up is a measure of the level of advancement of nanotechnology


NANOMACHINES
Manufactured products are made from atoms. The properties of those products depend on
how those atoms are arranged. If we rearrange the atoms in coal we can make diamond. If we
rearrange the atoms in sand (and add a few other trace elements) we can make computer
chips. If we rearrange the atoms in dirt, water and air we can make potatoes.
In future we'll be able to snap together the fundamental building blocks of nature easily,
inexpensively and in most of the ways permitted by the laws of physics. This will be
essential if we are to continue the revolution in computer hardware beyond about the next
decade, and will also let us fabricate an entire new generation of products that are cleaner,
stronger, lighter, and more precise.
101seminartopics.com

Thus molecular nanotechnology should let us :

   ๏ƒ˜ Get essentially every atom in the right place.
   ๏ƒ˜ Make almost any structure consistent with the laws of physics that we can specify in
     molecular detail.
   ๏ƒ˜ Have manufacturing costs not greatly exceeding the cost of the required raw materials
     and energy.



There are basically two ways to fabricate nanodevices:

   ๏ƒ˜ Self assembly
   ๏ƒ˜ Positional control



Self Assembly

The ability of chemists to synthesize what they want by stirring things together is truly
remarkable. Imagine building a radio by putting all the parts in a bag, shaking, and pulling
out the radio -- fully assembled and ready to work! Self assembly -- the art and science of
arranging conditions so that the parts themselves spontaneously assemble into the desired
structure -- is a well established and powerful method of synthesizing complex molecular
structures.

A basic principle in self assembly is selective stickiness: if two molecular parts have
complementary shapes and charge patterns -- one part has a hollow where the other part has a
bump, and one part has a positive charge where the other part has a negative charge -- then
they will tend to stick together in one particular way. By shaking these parts around --
something which thermal noise does for us quite naturally if the parts are floating in solution
-- the parts will eventually, purely by chance, be brought together in just the right way and
combine into a bigger part. This bigger part can combine in the same way with other parts,
letting us gradually build a complex whole from molecular pieces by stirring them together
and shaking.

Many viruses use this approach to make more viruses -- if you stir the parts of the T4
bacteriophage together in a test tube, they will self assemble into fully functional viruses.

Positional devices and positionally controlled reactions
101seminartopics.com

While self assembly is a path to nanotechnology, by itself it would be hard pressed to make
the very wide range of products promised by nanotechnology. During self assembly the parts
bounce around and bump into each other in all kinds of ways, and if they stick together when
we don't want them to stick together, we'll get unwanted globs of random parts.

Many types of parts have this problem, so self assembly won't work for them. These parts
can't be allowed to randomly bump into each other (or much of anything else, for that matter)
because they'd stick together when we didn't want them to stick together and form messy
blobs instead of precise molecular machines.




We can avoid this problem if we can hold and position the parts. Even though the molecular
parts that are used to make diamond are both indiscriminately and very sticky (more
technically, the barriers to bond formation are low and the resulting covalent bonds are quite
strong), if we can position them we can prevent them from bumping into each other in the
wrong way.

When two sticky parts do come into contact with each other, they'll do so in the right
orientation because we're holding them in the right orientation. In short, positional control at
the molecular scale should let us make things which would be difficult or impossible to make
without it.

If we are to position molecular parts we must develop the molecular equivalent of "arms" and
"hands." We'll need to learn what it means to "pick up" such parts and "snap them together.
101seminartopics.com




One of the first questions we'll need to answer is: what does a molecular-scale positional
device look like? Current proposals are similar to macroscopic robotic devices but on a much
smaller scale. The illustrations show a design for a molecular-scale robotic arm proposed by
Eric Drexler, a pioneering researcher in the field. Only 100 nanometers high and 30
nanometers in diameter, this rather squat design has a few million atoms and roughly a
hundred moving parts. It uses no lubricants, for at this scale a lubricant molecule is more like
a piece of grit.




Stiffness

Our molecular arms will be buffeted by something we don't worry about at the macroscopic
scale: thermal noise. This makes molecular-scale objects wiggle and jiggle, just as Brownian
motion makes small dust particles bounce around at random.
The critical property we need here is stiffness. Stiffness is a measure of how far something
moves when you push on it.
Unfortunately, as we make our positional devices smaller and smaller, they will be more and
more subject to thermal noise. To make something that's both small and stiff is more
challenging. It helps to get the stiffest material you can find. Diamond, as usual, is stiffer
than almost anything else and is an excellent material from which to make a very small, very
stiff positional device. Theoretical analysis gives firm support to the idea that positional
devices in the 100 nanometer size range able to position their tips to within a small fraction
of an atomic diameter in the face of thermal noise at room temperature should be feasible.




STEWART PLATFORM
While Drexler's proposal for a small robotic arm is easy to understand and should be
adequate to the task, more recent work has focused on the Stewart platform. This positional
device has the great advantage that it is stiffer than a robotic arm of similar size.
101seminartopics.com




If we want a full six degrees of freedom (X, Y, Z, roll, pitch and yaw) then we must be able
to independently adjust the lengths of six different edges of the polyhedron. If we further
want one triangular face of the polyhedron to remain of fixed size and hold a "tool," and a
second face of the polyhedron to act as the "base" whose size and position is fixed, then we
find that the simplest polyhedron that will suit our purpose is the octahedron.


The advantage of the Stewart platform can now be seen: because the six adjustable-length
edges are either in pure compression or pure tension and are never subjected to any bending
force, this positional device is stiffer than a long robotic arm which can bend and flex. The
Stewart platform is also conceptually simpler than a robotic arm, having fewer different types
of parts; for this reason, we can reasonably expect that making one will be simpler than
making a robotic.


Self replication: making things inexpensively

Positional control combined with appropriate molecular tools should let us build a truly
staggering range of molecular structures -- but a few molecular devices built at great expense
would hardly seem to qualify as a revolution in manufacturing. How can we keep the costs
down?

The requirement for low cost creates an interest in self replicating manufacturing systems.
These systems are able both to make copies of themselves and to manufacture useful
101seminartopics.com

products. If we can design and build one such system the manufacturing costs for more such
systems and the products they make (assuming they can make copies of themselves in some
reasonably inexpensive environment) will be very low.

Once the product has been assembled by assemblers and time of production quickened using
replicators, the assemblers are no more needed in them. The miniature devices used to
dissemble these assemblers are known as DISSEMBLERS. They function opposite to the
assemblers by breaking bonds between the atoms of assemblers and reducing them to junk
atoms.




VISUAL IMAGES IN NANOTECHNOLOGY




Nanogears no more than a a nanometer wide could be used to construct a matter compiler,
  Nanogears no more than nanometer wide could be used to construct a matter compiler, which
could becould be materialmaterial to arrange atoms andmacro-scale structure.
  which fed raw fed raw to arrange atoms and build a build a macro-scale structure.
101seminartopics.com




  A NANO-PUMP
  A NANO PUMP                        A DIFFERENTIAL
                               A DIFFERENTIAL GEAR       A FINE MOTION
                                                      A FINE MOTION
                                                      CONTROLLER
                                       GEAR              CONTROLLER




          A BEARING                            A HYDROCARBON JOINT




APPLICATIONS


Dip_Pen Nanolithography
"One molecule thick letters written using
Dip-Pen Nanolithography:
Octadecanethiol is the ink and gold is the
substrate. Visualized with an atomic force
microscope.
101seminartopics.com




NANOTECHNOLOGY AS AN ANALOGY



Nanotechnology is likely to change the way almost everything, including medicine,
computers and cars, are designed and constructed. Nanotechnology is anywhere from five to
15 years in the future, and we won't see dramatic changes in our world right away. But let's
take a look at the potential effects of nanotechnology:



         ๏‚ท   The first products made from nanomachines will be stronger fibers. Eventually,

Technology                     Function                      Molecular Examples
struts, beams, casins          transmit force, hold positions cell walls, microtubules
cables                         transmit tension              collagen, silk
fasteners, glue                connect parts                 intermolecular forces
solenoids, actuators           move things                   muscle actin, myosin
motors                         turn shafts                   flagellar motor
drive shafts                   transmit torque               bacterial flagella
bearings                       support moving parts          single bonds
clamps                         hold workpieces               enzymatic binding sites
tools                          modify workpieces             enzymes, reactive molecules
production lines               control devices               enzyme systems, ribosomes
numerical control systems      store and read programs       genetic system
101seminartopics.com

        we will be able to replicate anything, including diamonds, water and food. Famine
        could be eradicated by machines that fabricate foods to feed the hungry.



    ๏‚ท   In the computer industry, the ability to shrink the size of transistors on silicon
        microprocessors will soon reach its limits. Nanotechnology will be needed to
        create a new generation of computer components. Molecular computers could
        contain storage devices capable of storing trillions of bytes of information in a
        structure the size of a sugar cube.



    ๏‚ท   Nanotechnology may have its biggest impact on the medical industry. Patients
        will drink fluids containing nanorobots programmed to attack and reconstruct the
        molecular structure of cancer cells and viruses to make them harmless. There's
        even speculation that nanorobots could slow or reverse the aging process, and life
        expectancy could increase significantly. Nanorobots could also be programmed to
        perform delicate surgeries -- such nanosurgeons could work at a level a thousand
        times more precise than the sharpest scalpel. By working on such a small scale, a
        nanorobot could operate without leaving the scars that conventional surgery does.
        Additionally, nanorobots could change your physical appearance. They could be
        programmed to perform cosmetic surgery, rearranging your atoms to change your
        ears, nose, eye color or any other physical feature you wish to alter.




    ๏‚ท   Nanotechnology has the potential to have a positive effect on the environment.
        For instance, airborne nanorobots could be programmed to rebuild the thinning
        ozone layer. Contaminants could be automatically removed from water sources,
        and oil spills could be cleaned up instantly. Manufacturing materials using the
        bottom-up method of nanotechnology also creates less pollution than
        conventional manufacturing processes. Our dependence on non-renewable
        resources would diminish with nanotechnology. Many resources could be
        constructed by nanomachines. Cutting down trees, mining coal or drilling for oil
        may no longer be necessary. Resources could simply be constructed by
        nanomachines.
    ๏‚ท   One challenge to effective drug treatment is getting the medication to exactly the
        right place. To that end, researchers have been investigating myriad new methods
        to deliver pharmaceuticals. New findings indicate that tiny nanocontainers
        composed of polymers may one day distribute drugs to specific spots within
        individual cells
101seminartopics.com



        ๏‚ท   New findings suggest that artificial leaves comprised of nanocrystals may one day
            remove carbon dioxide from the atmosphere--even in the dark



        ๏‚ท   Research suggests that the diminutive tubes can hold twice as much energy as
            graphite, the form of carbon currently used as an electrode in many rechargeable
            lithium batteries



            CHALLENGES
            Things behave substantially differently in the micro domain. Forces related to
            volume, like weight and inertia, tend to decrease in significance. Forces related to
            surface area, such as friction and electrostatics, tend to become large. And forces
            like surface tension that depend upon an edge become enormous. It takes awhile
            to get one's micro intuition sorted out. Some people have come up with obstacles
            which raise doubts about the question:

                ๏‚ท   โ€Will it work?โ€
                ๏‚ท   โ€œWill Thermal Vibrations Mess Things Up?"
                ๏‚ท   โ€œWill Quantum Uncertainty Mess Things Up?"
                ๏‚ท   "Will Loose Molecules Mess Things Up?"
                ๏‚ท   โ€œWill Chemical Instability Mess Things Up?โ€


ETHICAL ISSUES


Some people have recently, publicly (and belatedly) realized that nanotechnology might create new
concerns that we should address.

Deliberate abuse, the misuse of a technology by some small group or nation to cause great harm, is
best prevented by measures based on a clear understanding of that technology. Nanotechnology
could, in the future, be used to rapidly identify and block attacks. Distributed surveillance systems
could quickly identify arms buildups and offensive weapons deployments, while lighter, stronger, and
smarter materials controlled by powerful molecular computers would let us make radically improved
versions of existing weapons able to respond to such threats.

Replicating manufacturing systems could rapidly churn out the needed defenses in huge quantities.
Such systems are best developed by continuing a vigorous R&D program, which provides a clear
understanding of the potential threats and countermeasures available.
101seminartopics.com

Besides deliberate attacks, the other concern is that a self-replicating molecular machine could
replicate unchecked, converting most of the biosphere into copies of itself. Some precautionary
measures include such common sense principles as: artificial replicators must not be capable of
replication in a natural, uncontrolled environment; they must have an absolute dependence on an
artificial fuel source or artificial components not found in nature; they must use appropriate error
detection codes and encryption to prevent unintended alterations in their blueprints; and the like.

CONCLUSION

The promises of nanotechnology sound great, don't they? Maybe even unbelievable? But
researchers say that we will achieve these capabilities within the next century. And if
nanotechnology is, in fact, realized, it might be the human race's greatest scientific
achievement yet, completely changing every aspect of the way we live.

Nanotechnology's potential to improve the human condition is staggering: we would be
shirking our duty to future generations if we did not responsibly develop it.




        BIBLIOGRAPHY

    ๏‚ท   Electronics for you
    ๏‚ท   www.yahoosearch.com
    ๏‚ท   www.rediffsearch.com
    ๏‚ท   www.howstuffworks.com
    ๏‚ท   Unbounding the future

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80 nanotechnology

  • 1. 101seminartopics.com NanoTechnology ABSTRACT A nanometer is one billionth of a meter. If you blew up a baseball to the size of the earth, the atoms would become visible, about the size of grapes. Some 3- 4 atoms fit lined up inside a nanometer. Nanotechnology is about building things atom by atom, molecule by molecule. The trick is to be able to manipulate atoms individually, and place them where you wish on a structure. Nanotechnology uses well known physical properties of atoms and molecules to make novel devices with extraordinary properties. The anticipated pay off for mastering this technology is beyond any human accomplishment thus far. Nature uses molecular machines to create life.Scientists from several fields including chemistry, biology, physics, and electronics are driving towards the precise manipulation of matter on the atomic scale. How do we get to nanotechnology? Several approaches seem feasible. Ultimately a combination may be the key. The goal of early nanotechnology is to produce the first nano-sized robot arm capable of manipulating atoms and molecules into a useful product or copies of itself. Nanotechnology finds applications as nanotubes, in nanomedicine and so on.Soon you have trillions of assemblers controlled by nano super computers working in parallel assembling objects quickly.
  • 2. 101seminartopics.com Ultimately, with atomic precision, everything could be made. It's all a matter of software. CONTENTS * INTRODUCTION * NANOTECHNOLOGY -AN INTERDISCIPLINARY SUBJECT * BOTTOM-UP TECHNOLOGY * NANOMACHINES * FABRICATION * STEWART PLATFORM * VISUAL IMAGES IN NANO TECNOLOGY * APPLICATIONS
  • 3. 101seminartopics.com * CHALLENGES * ETHICAL ISSUES * CONCLUSION * BIBLIOGRAPHY INTRODUCTION A nanometer is one billionth of a meter. That's a thousand, million times smaller than a meter. If you blew up a baseball to the size of the earth, the atoms would become visible, about the size of grapes. Some 3- 4 atoms fit lined up inside a nanometer. Nanotechnology is about building things atom-by-atom, molecule-by-molecule. The trick is to be able to manipulate atoms individually, and place them where you wish on a structure. Thus nanotechnology can be defined as: โ€œThorough, inexpensive control of the structure of matter based on molecule-by-molecule control of products and byproducts; the products and processes of molecular manufacturing. โ€œ LEARNING FROM NATURE Technology-as-we-know-it is a product of industry, of manufacturing and chemical engineering. Industry-as-we-know-it takes things from natureโ€”ore from mountains, trees from forestsโ€”and coerces them into forms that someone considers useful. Trees become lumber, then houses. Mountains become rubble, then molten iron, then steel, then cars. Sand becomes a purified gas, then silicon, and then chips. And so it goes. Each process is crude, based on cutting, stirring, baking, spraying, etching, grinding, and the like. Trees, though, are not crude: To make wood and leaves, they neither cut, grind, stir, bake, spray, etch, nor grind. Instead, they gather solar energy using molecular electronic devices, the photosynthetic reaction centers of chloroplasts. They use that energy to drive molecular machinesโ€”active devices with moving parts of precise, molecular structureโ€”which process carbon dioxide and water into oxygen and molecular building blocks. They use other
  • 4. 101seminartopics.com molecular machines to join these molecular building blocks to form roots, trunks, branches, twigs, solar collectors, and more molecular machinery. Every tree makes leaves, and each leaf is more sophisticated than a spacecraft, more finely patterned than the latest chip from Silicon Valley. They do all this without noise, heat, toxic fumes, or human labor, and they consume pollutants as they go. Viewed this way, trees are high technology. Chips and rockets aren't. Trees give a hint of what molecular nanotechnology will be like, but nanotechnology won't be biotechnology. Like biotechnologyโ€”or ordinary treesโ€”molecular nanotechnology will use molecular machinery, but unlike biotechnology, it will not rely on genetic meddling. THE SCALE We humans are huge creations with no direct experience of the molecular world, and this can make nanotechnology hard to visualize, hence hard to understand. The nano in nanotechnology comes from nanos, the Greek word for dwarf. In science, the prefix nano- means one-billionth of something, as in nanometer and nanosecond, which are typical units of size and time in the world of molecular manufacturing. Lets try to visualize: you say, "Shrink me!", and the world seems to expand. Frame (A) shows a hand holding a computer chip. This is shown magnified 100 times in (B). Another factor of 100 magnification (C) shows a living cell placed on the chip to show scale. Yet another factor of 100 magnification (D) shows two nanocomputers beside the cell. The smaller (shown as block) has roughly the same power as the chip seen in the first view; the larger (with only the corner visible) is as powerful as mid-1980s mainframe computer. Another factor of 100 magnification (E) shows an irregular protein from the cell on the lower right, and a cylindrical gear made by molecular manufacturing at top left. Taking a smaller factor of 10 jump, (F) shows two atoms in the protein, with electron clouds represented by stippling. A final factor of 100 magnification (G) reveals the nucleus of the atom as a tiny speck.
  • 5. 101seminartopics.com NANOTECHNOLOGY-AS AN INTERDISCIPLINARY SUBJECT Another feature of nanotechnology is that it is the one area of research and development that is truly multidisciplinary. Research at the nanoscale is unified by the need to share knowledge on tools and techniques, as well as information on the physics affecting atomic and molecular interactions in this new realm. Materials scientists, mechanical and electronic engineers and medical researchers are now forming teams with biologists, physicists and chemists TOP-DOWN BOTTOM-UP 'Top-down' refers to making nano scale structures 'Bottom-up', or molecular nanotechnology, by machining and etching techniques. applies to building organic and inorganic structures atom-by-atom, or molecule-by- molecule. Microscopic irregularities will always be present. Atomic scale manufacturing is devoid of all possible irregularities. Bonds cannot be manipulated. Thus new materials cannot be formed. Manipulation of bonds enables creation of new Eg. Silicon crystal๏ƒ  sliced๏ƒ required atomic materials with desired properties. scale silicon wafer obtained. Eg. Silicon atoms๏ƒ  assembled by suitable techniques๏ƒ  required atomic scale silicon wafer obtained. BOTTOM-UP TECHNOLOGY The two fundamentally different approaches to nanotechnology are graphically termed 'top down' and 'bottom up'. 'Top-down' refers to making nanoscale structures by machining and etching techniques, whereas 'bottom-up', or molecular nanotechnology, applies to building organic and inorganic structures atom-by-atom, or molecule-by-molecule. Top-down or bottom-up is a measure of the level of advancement of nanotechnology NANOMACHINES Manufactured products are made from atoms. The properties of those products depend on how those atoms are arranged. If we rearrange the atoms in coal we can make diamond. If we rearrange the atoms in sand (and add a few other trace elements) we can make computer chips. If we rearrange the atoms in dirt, water and air we can make potatoes. In future we'll be able to snap together the fundamental building blocks of nature easily, inexpensively and in most of the ways permitted by the laws of physics. This will be essential if we are to continue the revolution in computer hardware beyond about the next decade, and will also let us fabricate an entire new generation of products that are cleaner, stronger, lighter, and more precise.
  • 6. 101seminartopics.com Thus molecular nanotechnology should let us : ๏ƒ˜ Get essentially every atom in the right place. ๏ƒ˜ Make almost any structure consistent with the laws of physics that we can specify in molecular detail. ๏ƒ˜ Have manufacturing costs not greatly exceeding the cost of the required raw materials and energy. There are basically two ways to fabricate nanodevices: ๏ƒ˜ Self assembly ๏ƒ˜ Positional control Self Assembly The ability of chemists to synthesize what they want by stirring things together is truly remarkable. Imagine building a radio by putting all the parts in a bag, shaking, and pulling out the radio -- fully assembled and ready to work! Self assembly -- the art and science of arranging conditions so that the parts themselves spontaneously assemble into the desired structure -- is a well established and powerful method of synthesizing complex molecular structures. A basic principle in self assembly is selective stickiness: if two molecular parts have complementary shapes and charge patterns -- one part has a hollow where the other part has a bump, and one part has a positive charge where the other part has a negative charge -- then they will tend to stick together in one particular way. By shaking these parts around -- something which thermal noise does for us quite naturally if the parts are floating in solution -- the parts will eventually, purely by chance, be brought together in just the right way and combine into a bigger part. This bigger part can combine in the same way with other parts, letting us gradually build a complex whole from molecular pieces by stirring them together and shaking. Many viruses use this approach to make more viruses -- if you stir the parts of the T4 bacteriophage together in a test tube, they will self assemble into fully functional viruses. Positional devices and positionally controlled reactions
  • 7. 101seminartopics.com While self assembly is a path to nanotechnology, by itself it would be hard pressed to make the very wide range of products promised by nanotechnology. During self assembly the parts bounce around and bump into each other in all kinds of ways, and if they stick together when we don't want them to stick together, we'll get unwanted globs of random parts. Many types of parts have this problem, so self assembly won't work for them. These parts can't be allowed to randomly bump into each other (or much of anything else, for that matter) because they'd stick together when we didn't want them to stick together and form messy blobs instead of precise molecular machines. We can avoid this problem if we can hold and position the parts. Even though the molecular parts that are used to make diamond are both indiscriminately and very sticky (more technically, the barriers to bond formation are low and the resulting covalent bonds are quite strong), if we can position them we can prevent them from bumping into each other in the wrong way. When two sticky parts do come into contact with each other, they'll do so in the right orientation because we're holding them in the right orientation. In short, positional control at the molecular scale should let us make things which would be difficult or impossible to make without it. If we are to position molecular parts we must develop the molecular equivalent of "arms" and "hands." We'll need to learn what it means to "pick up" such parts and "snap them together.
  • 8. 101seminartopics.com One of the first questions we'll need to answer is: what does a molecular-scale positional device look like? Current proposals are similar to macroscopic robotic devices but on a much smaller scale. The illustrations show a design for a molecular-scale robotic arm proposed by Eric Drexler, a pioneering researcher in the field. Only 100 nanometers high and 30 nanometers in diameter, this rather squat design has a few million atoms and roughly a hundred moving parts. It uses no lubricants, for at this scale a lubricant molecule is more like a piece of grit. Stiffness Our molecular arms will be buffeted by something we don't worry about at the macroscopic scale: thermal noise. This makes molecular-scale objects wiggle and jiggle, just as Brownian motion makes small dust particles bounce around at random. The critical property we need here is stiffness. Stiffness is a measure of how far something moves when you push on it. Unfortunately, as we make our positional devices smaller and smaller, they will be more and more subject to thermal noise. To make something that's both small and stiff is more challenging. It helps to get the stiffest material you can find. Diamond, as usual, is stiffer than almost anything else and is an excellent material from which to make a very small, very stiff positional device. Theoretical analysis gives firm support to the idea that positional devices in the 100 nanometer size range able to position their tips to within a small fraction of an atomic diameter in the face of thermal noise at room temperature should be feasible. STEWART PLATFORM While Drexler's proposal for a small robotic arm is easy to understand and should be adequate to the task, more recent work has focused on the Stewart platform. This positional device has the great advantage that it is stiffer than a robotic arm of similar size.
  • 9. 101seminartopics.com If we want a full six degrees of freedom (X, Y, Z, roll, pitch and yaw) then we must be able to independently adjust the lengths of six different edges of the polyhedron. If we further want one triangular face of the polyhedron to remain of fixed size and hold a "tool," and a second face of the polyhedron to act as the "base" whose size and position is fixed, then we find that the simplest polyhedron that will suit our purpose is the octahedron. The advantage of the Stewart platform can now be seen: because the six adjustable-length edges are either in pure compression or pure tension and are never subjected to any bending force, this positional device is stiffer than a long robotic arm which can bend and flex. The Stewart platform is also conceptually simpler than a robotic arm, having fewer different types of parts; for this reason, we can reasonably expect that making one will be simpler than making a robotic. Self replication: making things inexpensively Positional control combined with appropriate molecular tools should let us build a truly staggering range of molecular structures -- but a few molecular devices built at great expense would hardly seem to qualify as a revolution in manufacturing. How can we keep the costs down? The requirement for low cost creates an interest in self replicating manufacturing systems. These systems are able both to make copies of themselves and to manufacture useful
  • 10. 101seminartopics.com products. If we can design and build one such system the manufacturing costs for more such systems and the products they make (assuming they can make copies of themselves in some reasonably inexpensive environment) will be very low. Once the product has been assembled by assemblers and time of production quickened using replicators, the assemblers are no more needed in them. The miniature devices used to dissemble these assemblers are known as DISSEMBLERS. They function opposite to the assemblers by breaking bonds between the atoms of assemblers and reducing them to junk atoms. VISUAL IMAGES IN NANOTECHNOLOGY Nanogears no more than a a nanometer wide could be used to construct a matter compiler, Nanogears no more than nanometer wide could be used to construct a matter compiler, which could becould be materialmaterial to arrange atoms andmacro-scale structure. which fed raw fed raw to arrange atoms and build a build a macro-scale structure.
  • 11. 101seminartopics.com A NANO-PUMP A NANO PUMP A DIFFERENTIAL A DIFFERENTIAL GEAR A FINE MOTION A FINE MOTION CONTROLLER GEAR CONTROLLER A BEARING A HYDROCARBON JOINT APPLICATIONS Dip_Pen Nanolithography "One molecule thick letters written using Dip-Pen Nanolithography: Octadecanethiol is the ink and gold is the substrate. Visualized with an atomic force microscope.
  • 12. 101seminartopics.com NANOTECHNOLOGY AS AN ANALOGY Nanotechnology is likely to change the way almost everything, including medicine, computers and cars, are designed and constructed. Nanotechnology is anywhere from five to 15 years in the future, and we won't see dramatic changes in our world right away. But let's take a look at the potential effects of nanotechnology: ๏‚ท The first products made from nanomachines will be stronger fibers. Eventually, Technology Function Molecular Examples struts, beams, casins transmit force, hold positions cell walls, microtubules cables transmit tension collagen, silk fasteners, glue connect parts intermolecular forces solenoids, actuators move things muscle actin, myosin motors turn shafts flagellar motor drive shafts transmit torque bacterial flagella bearings support moving parts single bonds clamps hold workpieces enzymatic binding sites tools modify workpieces enzymes, reactive molecules production lines control devices enzyme systems, ribosomes numerical control systems store and read programs genetic system
  • 13. 101seminartopics.com we will be able to replicate anything, including diamonds, water and food. Famine could be eradicated by machines that fabricate foods to feed the hungry. ๏‚ท In the computer industry, the ability to shrink the size of transistors on silicon microprocessors will soon reach its limits. Nanotechnology will be needed to create a new generation of computer components. Molecular computers could contain storage devices capable of storing trillions of bytes of information in a structure the size of a sugar cube. ๏‚ท Nanotechnology may have its biggest impact on the medical industry. Patients will drink fluids containing nanorobots programmed to attack and reconstruct the molecular structure of cancer cells and viruses to make them harmless. There's even speculation that nanorobots could slow or reverse the aging process, and life expectancy could increase significantly. Nanorobots could also be programmed to perform delicate surgeries -- such nanosurgeons could work at a level a thousand times more precise than the sharpest scalpel. By working on such a small scale, a nanorobot could operate without leaving the scars that conventional surgery does. Additionally, nanorobots could change your physical appearance. They could be programmed to perform cosmetic surgery, rearranging your atoms to change your ears, nose, eye color or any other physical feature you wish to alter. ๏‚ท Nanotechnology has the potential to have a positive effect on the environment. For instance, airborne nanorobots could be programmed to rebuild the thinning ozone layer. Contaminants could be automatically removed from water sources, and oil spills could be cleaned up instantly. Manufacturing materials using the bottom-up method of nanotechnology also creates less pollution than conventional manufacturing processes. Our dependence on non-renewable resources would diminish with nanotechnology. Many resources could be constructed by nanomachines. Cutting down trees, mining coal or drilling for oil may no longer be necessary. Resources could simply be constructed by nanomachines. ๏‚ท One challenge to effective drug treatment is getting the medication to exactly the right place. To that end, researchers have been investigating myriad new methods to deliver pharmaceuticals. New findings indicate that tiny nanocontainers composed of polymers may one day distribute drugs to specific spots within individual cells
  • 14. 101seminartopics.com ๏‚ท New findings suggest that artificial leaves comprised of nanocrystals may one day remove carbon dioxide from the atmosphere--even in the dark ๏‚ท Research suggests that the diminutive tubes can hold twice as much energy as graphite, the form of carbon currently used as an electrode in many rechargeable lithium batteries CHALLENGES Things behave substantially differently in the micro domain. Forces related to volume, like weight and inertia, tend to decrease in significance. Forces related to surface area, such as friction and electrostatics, tend to become large. And forces like surface tension that depend upon an edge become enormous. It takes awhile to get one's micro intuition sorted out. Some people have come up with obstacles which raise doubts about the question: ๏‚ท โ€Will it work?โ€ ๏‚ท โ€œWill Thermal Vibrations Mess Things Up?" ๏‚ท โ€œWill Quantum Uncertainty Mess Things Up?" ๏‚ท "Will Loose Molecules Mess Things Up?" ๏‚ท โ€œWill Chemical Instability Mess Things Up?โ€ ETHICAL ISSUES Some people have recently, publicly (and belatedly) realized that nanotechnology might create new concerns that we should address. Deliberate abuse, the misuse of a technology by some small group or nation to cause great harm, is best prevented by measures based on a clear understanding of that technology. Nanotechnology could, in the future, be used to rapidly identify and block attacks. Distributed surveillance systems could quickly identify arms buildups and offensive weapons deployments, while lighter, stronger, and smarter materials controlled by powerful molecular computers would let us make radically improved versions of existing weapons able to respond to such threats. Replicating manufacturing systems could rapidly churn out the needed defenses in huge quantities. Such systems are best developed by continuing a vigorous R&D program, which provides a clear understanding of the potential threats and countermeasures available.
  • 15. 101seminartopics.com Besides deliberate attacks, the other concern is that a self-replicating molecular machine could replicate unchecked, converting most of the biosphere into copies of itself. Some precautionary measures include such common sense principles as: artificial replicators must not be capable of replication in a natural, uncontrolled environment; they must have an absolute dependence on an artificial fuel source or artificial components not found in nature; they must use appropriate error detection codes and encryption to prevent unintended alterations in their blueprints; and the like. CONCLUSION The promises of nanotechnology sound great, don't they? Maybe even unbelievable? But researchers say that we will achieve these capabilities within the next century. And if nanotechnology is, in fact, realized, it might be the human race's greatest scientific achievement yet, completely changing every aspect of the way we live. Nanotechnology's potential to improve the human condition is staggering: we would be shirking our duty to future generations if we did not responsibly develop it. BIBLIOGRAPHY ๏‚ท Electronics for you ๏‚ท www.yahoosearch.com ๏‚ท www.rediffsearch.com ๏‚ท www.howstuffworks.com ๏‚ท Unbounding the future