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STOP Sepsis 6-hour  Strategies to  Timely  Obviate the  Progression of Sepsis 6-hour STOP Bundle summarized by sun yaicheng http://decode-medicine.blogspot.com/
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock Rivers E.  N Engl J Med 2001;345:1368-77.
Sepsis SIRS Severe Sepsis Septic Shock Sepsis SIRS Severe Sepsis Septic Shock Systemic Inflammatory Response Syndrome  ,[object Object]
HR > 90
RR > 20 or PCO2 < 32
WBC < 4K or > 12K or bands > 10%Bone et al. Chest 1992;101:1644
SIRS Severe Sepsis Septic Shock Sepsis SIRS with Infection Bone et al. Chest 1992;101:1644
SIRS Severe Sepsis Septic Shock Sepsis Sepsis plus Organ Dysfunction ,[object Object]
Elevated INR (DIC)
Altered Mental Status (GCS <12)
Elevated Lactate (>4)
Hypotension that responds to fluidBone et al. Chest 1992;101:1644
SIRS Severe Sepsis Septic Shock Sepsis Severe Sepsis and Hypotension ,[object Object],Bone et al. Chest 1992;101:1644
Criteria to initiate the bundle SIRS plus source of infection plus a ,[object Object]
Lactate > 4 mmol/L
Organ dysfunctionSTOP SEPSIS SCCM 34th Critical Care Congress: Abstract 44. Presented Jan. 17,2005.
STOP Bundle Strategies ,[object Object]

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