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Masks of kidney tuberculosis

                E. Kulchavenya,
                E. Brizhatyuk, D. Kholtobin


                 Novosibirsk, Russia, e-mail: ku_ekaterina@mail.ru

Introduction. The main reason for late diagnosis of UGTB is an
atypical clinical feature of UGTB, it courses under the mask of
another disease.
Material & Methods: We analyzed 816 history cases of UGTB
patients to estimate clinical features.
Results: Most common complains were flank pain (68%),
dysuria (48%) and renal colic (24%); among laboratory signs -
pyuria (78%) and haematuria (34%). Patients were treated by
urologists or GPs with misdiagnoses of pyelonephritis (27%),
cystitis (43%), cancer (8%) or urolithiasis (22%) during 5.6 years
on average. Positive smear was in 17% and positive culture of
Mycobacterium tuberculosis was in 44%. 64% were diagnosed in
late complicated cavernous stage, when surgery is necessary –
and 90% of operations were nephrectomy due to total
involvement of kidney tissue.
Conclusions: Most common masks of UGTB are pyelonephritis,
cystitis and urolithiasis. UGTB presents non-specific symptoms
and laboratory findings, except for positive MBT culture, but
only about 44% cases are culture-positive. This is one of the
main reasons for late and poor diagnosis of UGTB. The
significance of UGTB may be considerable when the high
prevalence of overall TB and the asymptomatic nature of UGTB
are taken into account.

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  • 1. Masks of kidney tuberculosis E. Kulchavenya, E. Brizhatyuk, D. Kholtobin Novosibirsk, Russia, e-mail: ku_ekaterina@mail.ru Introduction. The main reason for late diagnosis of UGTB is an atypical clinical feature of UGTB, it courses under the mask of another disease. Material & Methods: We analyzed 816 history cases of UGTB patients to estimate clinical features. Results: Most common complains were flank pain (68%), dysuria (48%) and renal colic (24%); among laboratory signs - pyuria (78%) and haematuria (34%). Patients were treated by urologists or GPs with misdiagnoses of pyelonephritis (27%), cystitis (43%), cancer (8%) or urolithiasis (22%) during 5.6 years on average. Positive smear was in 17% and positive culture of Mycobacterium tuberculosis was in 44%. 64% were diagnosed in late complicated cavernous stage, when surgery is necessary – and 90% of operations were nephrectomy due to total involvement of kidney tissue. Conclusions: Most common masks of UGTB are pyelonephritis, cystitis and urolithiasis. UGTB presents non-specific symptoms and laboratory findings, except for positive MBT culture, but only about 44% cases are culture-positive. This is one of the main reasons for late and poor diagnosis of UGTB. The significance of UGTB may be considerable when the high prevalence of overall TB and the asymptomatic nature of UGTB are taken into account.