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Innovative 3d modeling in medicine




 Инновационные технологии
3d моделирования в медицине
Scope of the presentation…

• About Materialise
• Technical introduction:
- Starting from CT/MRI images, Mimics software can
  make an accurate 3D reconstruction of the
  anatomical structures and export STL files.
- 3-matic software is capable of designing implants
  based on these 3D reconstructions, on STL level
  (no reverse engineering necessary)
- The final implants can be produced by Direct Metal
  Laser Sintering
Materialise Ukraine
  • Office was established in August 2000 with 5
    members on board in collaboration
  • Now we are more than 250 people !

• Developers        • Application engineers
• Medical engineers • CAD engineers




                                               3
Welcome to Materialise
• Started in 1990 the technology of Rapid
  Prototyping (3D Printing)
  • As in a joint venture with University of Leuven
• Grown to over 900 employees worldwide
• HQ in Belgium, offices all around the world
• Now active in diverse domains...




                                                      4
Materialise
        Mission Statement

To innovate product development
resulting in a better and healthier world,
through its software and hardware infrastructure
and in-depth knowledge of Rapid Prototyping,
Tooling & Manufacturing.




                                                   5
3d printing: Rapid Prototyping




           Materialise Factory
Materialise software products
What is Mimics?

                                                                        3D Model
     • Mimics allows you to:
        • import scanned images
        • select structures in the images
     • These structures can then be
       used for different applications…




CT or MRI Scan       2-D Cross Sections                               Mimics Software
                   Prof. Dr. De Backer, UZ Antwerp, Dep. Pneumology
Mimics provides:

• A link between scanned images and...
                  • Rapid Prototyping
                  • CAD
                  • Finite Element Analysis
                  • Surgical Procedure Simulation
Rapid Prototyping

• Use Mimics for the production
• of Medical Models
  •   Easy Creation of STL files
  •   Direct export to RP formats
  •   Create Supports in Mimics
  •   Color stereolithography

• Medical Models:
  • Communication
  • Surgery Preparation
  • Proven to be very accurate
    and useful
       • (cfr. Phidias – European                  Dr. George A. Brown
                                    Kenneth E. Salyer, M.D., F.A.C.S., F.A.A.P., F.I.C.S.
         research project)
Flexible soft tissue models

• Creation of flexible soft tissue models for device
  design




              Angela Noecker, Lerner Research Institute
                     Noecker,
Design of custom implants




     Ralf Schindel, Hochschule St. Gallen
          Schindel,
Non invasive archeology




Dominic Eggbeer, The National Centre for Product Design & Development Research (PDR)
                                 The British Museum
Other possibilities
Mimics provides:

• A link between scanned images and...
                  • Rapid Prototyping
                  • CAD
                  • Finite Element Analysis
                  • Surgical Procedure Simulation
Transfer to CAD

• Transfer geometries accurately from
• scanned images to CAD software.
    • (cfr. Aesculap study)
Case Study 1

• An Automated System for Design and analysis of
  Total Hip Implants
  • Select information
  • Perform Statistics
  • Make new design




                   Mark A. Manasas - 1999
Mimics provides:

• A link between scanned images and...
                  • Rapid Prototyping
                  • CAD
                  • Finite Element Analysis
                  • Surgical Procedure Simulation
Finite Element Analysis

• Optimize your mesh for FE Analysis:
Finite Element Analysis

• Do an accurate material assignment to the
  volumetric mesh based on the HU in the CT
  images
Von Mises Stresses
Velocity pathlines from CFD
Computer Assisted Brain Analysis




   Andreas A. Linninger, University of Illinois at Chicago
Mimics provides:

• A link between scanned images and...
                  • Rapid Prototyping
                  • CAD
                  • Finite Element Analysis
                  • Surgical Procedure Simulation
Surgical procedure Simulation

• Use Mimics to simulate the implant positioning
• and to verify your design.




    Data courtesy of Dr. Taha
Surgical procedure Simulation

• Use Mimics to gather measurements for e.g.
  statistical analysis




                          Wan Abdul Rahman Wan Harun, SIRIM Berhad
Implant placement and surgical
simulation
The design of a custom prosthesis
                                    Materialise
Classification of cranial prosthesis

1. ‘Simple’ Cranial defect   3. Missing orbit




2. Large cranial defect
1. Design for a simple cranial defect
Strategy - Example
• Draw a curve around the defect    Curve
   • Make sure you draw it far
     enough from the border since
     we will make a tangential
     hole filling
• Use the “Create Cranioplasty
  Prosthesis” function
Result
2. Design for a large cranial defect
Example




          Dr. Haex, AZ Maastricht
3. Design for missing orbit
Example
          •The mirrored skull positioned at
          the desired spot




                                   Dr. Taha, CHU Amiens
Example: verification in Mimics
Materialise – Kiev Office




Materialise: innovative products – innovative services – innovative careers
materialise.kiev.ua
Learn more about us!


Materialise Ukraine
 vul. Raisy Okypnoi, 8A · 02002 Kyiv ·
 Ukraine
 Tel. +38 044 594 5610
Fax +38 044 594 5611
 www.materialise.com
 www.materialise.kiev.ua

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Innovative Technologies of 3D-Modelling in Medicine

  • 1. Innovative 3d modeling in medicine Инновационные технологии 3d моделирования в медицине
  • 2. Scope of the presentation… • About Materialise • Technical introduction: - Starting from CT/MRI images, Mimics software can make an accurate 3D reconstruction of the anatomical structures and export STL files. - 3-matic software is capable of designing implants based on these 3D reconstructions, on STL level (no reverse engineering necessary) - The final implants can be produced by Direct Metal Laser Sintering
  • 3. Materialise Ukraine • Office was established in August 2000 with 5 members on board in collaboration • Now we are more than 250 people ! • Developers • Application engineers • Medical engineers • CAD engineers 3
  • 4. Welcome to Materialise • Started in 1990 the technology of Rapid Prototyping (3D Printing) • As in a joint venture with University of Leuven • Grown to over 900 employees worldwide • HQ in Belgium, offices all around the world • Now active in diverse domains... 4
  • 5. Materialise Mission Statement To innovate product development resulting in a better and healthier world, through its software and hardware infrastructure and in-depth knowledge of Rapid Prototyping, Tooling & Manufacturing. 5
  • 6. 3d printing: Rapid Prototyping Materialise Factory
  • 8. What is Mimics? 3D Model • Mimics allows you to: • import scanned images • select structures in the images • These structures can then be used for different applications… CT or MRI Scan 2-D Cross Sections Mimics Software Prof. Dr. De Backer, UZ Antwerp, Dep. Pneumology
  • 9. Mimics provides: • A link between scanned images and... • Rapid Prototyping • CAD • Finite Element Analysis • Surgical Procedure Simulation
  • 10. Rapid Prototyping • Use Mimics for the production • of Medical Models • Easy Creation of STL files • Direct export to RP formats • Create Supports in Mimics • Color stereolithography • Medical Models: • Communication • Surgery Preparation • Proven to be very accurate and useful • (cfr. Phidias – European Dr. George A. Brown Kenneth E. Salyer, M.D., F.A.C.S., F.A.A.P., F.I.C.S. research project)
  • 11. Flexible soft tissue models • Creation of flexible soft tissue models for device design Angela Noecker, Lerner Research Institute Noecker,
  • 12. Design of custom implants Ralf Schindel, Hochschule St. Gallen Schindel,
  • 13. Non invasive archeology Dominic Eggbeer, The National Centre for Product Design & Development Research (PDR) The British Museum
  • 15. Mimics provides: • A link between scanned images and... • Rapid Prototyping • CAD • Finite Element Analysis • Surgical Procedure Simulation
  • 16. Transfer to CAD • Transfer geometries accurately from • scanned images to CAD software. • (cfr. Aesculap study)
  • 17. Case Study 1 • An Automated System for Design and analysis of Total Hip Implants • Select information • Perform Statistics • Make new design Mark A. Manasas - 1999
  • 18. Mimics provides: • A link between scanned images and... • Rapid Prototyping • CAD • Finite Element Analysis • Surgical Procedure Simulation
  • 19. Finite Element Analysis • Optimize your mesh for FE Analysis:
  • 20. Finite Element Analysis • Do an accurate material assignment to the volumetric mesh based on the HU in the CT images
  • 23. Computer Assisted Brain Analysis Andreas A. Linninger, University of Illinois at Chicago
  • 24. Mimics provides: • A link between scanned images and... • Rapid Prototyping • CAD • Finite Element Analysis • Surgical Procedure Simulation
  • 25. Surgical procedure Simulation • Use Mimics to simulate the implant positioning • and to verify your design. Data courtesy of Dr. Taha
  • 26. Surgical procedure Simulation • Use Mimics to gather measurements for e.g. statistical analysis Wan Abdul Rahman Wan Harun, SIRIM Berhad
  • 27. Implant placement and surgical simulation
  • 28. The design of a custom prosthesis Materialise
  • 29. Classification of cranial prosthesis 1. ‘Simple’ Cranial defect 3. Missing orbit 2. Large cranial defect
  • 30. 1. Design for a simple cranial defect
  • 31. Strategy - Example • Draw a curve around the defect Curve • Make sure you draw it far enough from the border since we will make a tangential hole filling • Use the “Create Cranioplasty Prosthesis” function
  • 33. 2. Design for a large cranial defect
  • 34. Example Dr. Haex, AZ Maastricht
  • 35. 3. Design for missing orbit
  • 36. Example •The mirrored skull positioned at the desired spot Dr. Taha, CHU Amiens
  • 38. Materialise – Kiev Office Materialise: innovative products – innovative services – innovative careers
  • 40. Learn more about us! Materialise Ukraine vul. Raisy Okypnoi, 8A · 02002 Kyiv · Ukraine Tel. +38 044 594 5610 Fax +38 044 594 5611 www.materialise.com www.materialise.kiev.ua