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Vitamin Dosage(s) Purpose
A (beta-carotene form) 2500 IU daily may be helpful as an anti-oxidant
Acetyl-L-Carnitine 500 mg daily Helps to reduce hypoglycemic episodes and secondary fatigue.
AFP-Peptizide (Houston's) 1 or 2 tabs or chewables w/meals Take with meals to aid in the digestion of casein and gluten.
B Vitamins: see below To help correct pyrroluria symptoms; to increase neurotransmitter production and improve dream recall.
To improve serotonin levels, decrease anxiety, and improve mood.
B6 25 mg once or twice daily
50 mg daily
100 – 200 mg daily
P5P 25 mg daily
50 – 100 mg daily
B2 (R5P) 5 – 10 mg daily
10 – 20 mg daily
B12 500 mcg daily For low histamine individuals (over-methylators), B12 in the form of cyanocobalamine is more appropriate.
1000 mcg once or twice daily
Biotin 600 mcg daily Useful in promoting better nutrient absorption.
300 mcg twice daily
C 150 – 200 mg twice daily Anti-oxidant benefits
250 mg twice daily Helps to reduce free copper.
500 mg twice daily
1000 mg twice daily
Calcium/Magnesium (~2:1) 250/100 mg Useful for bone health, calming, and helps to lower histamine.
200/100 mg daily May be useful to promote sleep, particularly when taken at bedtime.
500/250 mg daily
Chromium Polynicotinate 100 mg daily Helps to reduce hypoglycemic episodes and secondary fatigue and mood swings.
200 mg daily
Co10 50 – 100 mg daily
D 50 – 75 IU daily
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200 IU daily
400 – 1000 IU daily
DMG 250 mg daily Useful in supporting better mental focus and in the development of speech and language.
5 cc (liquid formulation) daily
E 25 – 50 IU daily
100-200 IU daily
400 IU daily
Folate (folic acid) 400 mcg daily Folate raises histamine levels.
800 – 1000 mcg twice daily Low histamine individuals need therapeutic doses of folic acid in efforts to normalize histamine levels.
GABA 500 mg once or twice daily May be helpful to promote calming.
Inositol 500 mg up to 3 times daily Helpful for calming, particularly in high histamine individuals.
L-Carnitine 500 mg twice daily Helps to manage blood sugars and decreases hypoglycemic tendencies and supports mitochondrial
efficiency in skeletal muscles regarding metabolism and energy expenditure.
Lithium Orotate 4 mg once or twice daily calming
Magnesium Glycinate 100 mg twice daily Helpful for calming.
200 mg before bedtime
Manganese 5 – 10 mg daily Helpls manage blood sugards.
Melatonin 3 mg 1-2 caps before bedtime May be helpful for sleep.
Molybdenum 250 mcg daily Facilitates the reduction in percent free copper.
Omega 3, fish oil 1 Tablespoon or capsule equiv. Anti-inflammatory properties. Nordic Naturals, Carlson or other reputable brand is recommended for daily use.
Omega 6, such as EPO 500 mg once or twice daily Helps to correct pyrrole disorder.
EPO or Borage Oil Borage Oil 1000 mg once daily Helps reduce symptoms of PMS.
Probiotics (acidophilus ) daily For GI health. Primal Defense Ultra and Therbiotic Complete are good broad spectrum brands
(contain at least 5 beneficial gut bacteria).
Selenium 50 mcg daily Useful as a powerful adjunct in anti-oxidant support and helpful for skin health along with zinc.
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Serine 100 – 200 mg daily
TMG (Trimethylglycine) 500 – 750 mg daily To help lower histamine.
Trienza (Houston's) 1 or 2 tabs or chewables w/meals To aid in the digestion of casein, gluten, and phenol (found in fruits and vegetables).
Tyrosine 500 mg For better focus and mental processing. Avoid use near bedtime.
Zinc Picolinate 10 – 25 mg daily To improve neurotransmitter production, correct pyrrole disorder and to decrease excess copper.
50 – 75 mg daily Supports immune system and is important for skin health.
Picolinate form preferred, Citrate form acceptable.
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