1) Diabetic neuropathy is a syndrome comprising separate clinical disorders that affect the peripheral nervous system, with a prevalence of 66% for type 1 diabetes and 59% for type 2 diabetes. 2) Risk factors include hyperglycemia, longer duration of diabetes, age, hypertension, and smoking. 3) The most common form is distal symmetrical sensorimotor polyneuropathy, which involves small and large fiber sensory, autonomic, and motor nerves in various combinations.