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A Case of Atypical Hemolytic Uremic Syndrome
- 1. PROF DR K H NOOR UL AMEEN M5 UNIT DR.RAKESH PINNINTI CASE OF JAUNDICE
- 13. RFT PROGRESSION Hemo-Dialysis started on 16/5/2011 14/5 15/5 17/5 20/5 21/5 22/5 24/5 26/5 Date 104 96 148 180 99 89 179 71 Urea 4.8 4.9 5.2 13.0 8.8 6.7 8.2 7.2 Creat
- 16. ONLINE REFERENCE Fibrin thrombi & RBC in renal capillaries Subintimal fibrin, but no inflammation Healing from prior fibrinoid injury, occluding vessel
- 18. FINAL DIAGNOSIS ATYPICAL HEMOLYTIC UREAMIC SYNDROME / D-HUS
- 19. TTP vs HUS
- 20. D+ vs. D-
- 23. Disseminated intravascular coagulation is not typically present, but may be seen when there is diffuse tissue ischemia.
- 24. Treatment
- 25. Prognosis Index contains three adverse prognostic factors (age >40, hemoglobin <9 g/dL, temperature >38.5ºC). Subjects with zero, one, two, or all three of these adverse factors had 6-month mortality rates of 12, 14, 31, and 62 percent, respectively. Atypical hemolytic–uremic syndrome has a poor prognosis, with death rates as high as 25% and progression to end-stage renal disease in half the patients
- 26. THANK YOU