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1	 Classification of the Antibiotics

b-Lactam antibiotics
Benzylpenicillins Phenoxy­penicillins 	
(oral penicillins)

Penicillinase-	
resistant penicillins (anti-staphylococcal penicillins)

Penicillin G
(benzylpenicillin
sodium, procaine
benzylpenicillin,
benzathine
peni­cillin)

Penicillin V
Propicillin

Oxacillin
Dicloxacillin
Flucloxacillin

Aminobenzyl­
penicillins

Ureidopenicillins
(broad-spectrum
penicillins)

ß-Lactam/	
ß-lactamase 	
inhibitors

Ampicillin
Amoxicillin

Mezlocillin
Piperacillin

Ampicillin/­
sulbactam
Amoxicillin/­
clavu­lanate
Piperacillin/
tazobactam
Sulbactam in free
combinations
    Classification of the Antibiotics

Cephalosporins Cephalosporins 	
(first generation) (second 	
generation)

Cephalosporins
(third and fourth
generation)

Cefazolin
Cefalexin (oral)
Cefadroxil (oral)

Cefuroxime
Cefotiam
Cefuroxime axetil
Cefaclor (oral)
Loracarbef

Cefotaxime
Ceftriaxone
Ceftazidime
Cefepime
Cefixime (oral)
Cefpodoxime
proxetil (oral)
Ceftibuten (oral)

Monobactams

Carbapenems

b-Lactamase 	
inhibitors

Aztreonam

Imipenem
Meropenem
Ertapenem
Doripenem

Clavulanic acid
Sulbactam
Tazobactam

Other substances
Aminoglycosides Tetracyclines

Quinolones

Streptomycin
Gentamicin
Tobramycin
Netilmicin
Amikacin

Group I:
Norfloxacin

Tetracycline
Doxycycline
Minocycline

Group II:
Enoxacin
Ofloxacin
Ciprofloxacin
Group III:
Levofloxacin
Group IV:
Moxifloxacin
Classification of the Antibiotics    

I: 	 Indications essentially limited to UTI
II: 	 Widely indicated
III: 	Improved activity against Gram-positive and atypical
pathogens
IV: 	Further enhanced activity against Gram-positive and
atypical pathogens, also against anaerobic bacteria
Lincosamides

Azol derivatives

Nitroimidazoles

Clindamycin

Miconazole
Ketoconazole
Fluconazole
Itraconazole
Voriconazole
Posaconazole

Metronidazole

Glycopeptide 	
antibiotics

Macrolides

Polyenes

Vancomycin
Teicoplanin
Telavancin

Erythromycin
Spiramycin
Roxithromycin
Clarithromycin
Azithromycin

Amphotericin B
Nystatin

Glycylcyclines

Echinocandins

Tigecycline

Caspofungin
Anidulafungin
Micafungin

Streptogramines Ketolides

Oxazolidinones

Quinupristin/
dalfopristin

Linezolid

Telithromycin
    Classification of the Antibiotics

Lipopeptides

Epoxides

Polymyxins

Daptomycin

Fosfomycin

Colistin
(polymyxin E)
Polymyxin B

Ansamycins
Rifampicin
http://www.springer.com/978-3-642-18401-7

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9783642184017 c1

  • 1. 1 Classification of the Antibiotics b-Lactam antibiotics Benzylpenicillins Phenoxy­penicillins (oral penicillins) Penicillinase- resistant penicillins (anti-staphylococcal penicillins) Penicillin G (benzylpenicillin sodium, procaine benzylpenicillin, benzathine peni­cillin) Penicillin V Propicillin Oxacillin Dicloxacillin Flucloxacillin Aminobenzyl­ penicillins Ureidopenicillins (broad-spectrum penicillins) ß-Lactam/ ß-lactamase inhibitors Ampicillin Amoxicillin Mezlocillin Piperacillin Ampicillin/­ sulbactam Amoxicillin/­ clavu­lanate Piperacillin/ tazobactam Sulbactam in free combinations
  • 2.     Classification of the Antibiotics Cephalosporins Cephalosporins (first generation) (second generation) Cephalosporins (third and fourth generation) Cefazolin Cefalexin (oral) Cefadroxil (oral) Cefuroxime Cefotiam Cefuroxime axetil Cefaclor (oral) Loracarbef Cefotaxime Ceftriaxone Ceftazidime Cefepime Cefixime (oral) Cefpodoxime proxetil (oral) Ceftibuten (oral) Monobactams Carbapenems b-Lactamase inhibitors Aztreonam Imipenem Meropenem Ertapenem Doripenem Clavulanic acid Sulbactam Tazobactam Other substances Aminoglycosides Tetracyclines Quinolones Streptomycin Gentamicin Tobramycin Netilmicin Amikacin Group I: Norfloxacin Tetracycline Doxycycline Minocycline Group II: Enoxacin Ofloxacin Ciprofloxacin Group III: Levofloxacin Group IV: Moxifloxacin
  • 3. Classification of the Antibiotics    I: Indications essentially limited to UTI II: Widely indicated III: Improved activity against Gram-positive and atypical pathogens IV: Further enhanced activity against Gram-positive and atypical pathogens, also against anaerobic bacteria Lincosamides Azol derivatives Nitroimidazoles Clindamycin Miconazole Ketoconazole Fluconazole Itraconazole Voriconazole Posaconazole Metronidazole Glycopeptide antibiotics Macrolides Polyenes Vancomycin Teicoplanin Telavancin Erythromycin Spiramycin Roxithromycin Clarithromycin Azithromycin Amphotericin B Nystatin Glycylcyclines Echinocandins Tigecycline Caspofungin Anidulafungin Micafungin Streptogramines Ketolides Oxazolidinones Quinupristin/ dalfopristin Linezolid Telithromycin
  • 4.     Classification of the Antibiotics Lipopeptides Epoxides Polymyxins Daptomycin Fosfomycin Colistin (polymyxin E) Polymyxin B Ansamycins Rifampicin