SilkSkin gloves is the latest glove innovation available today incorporating the tremendous cosmetic value in anti-aging properties. It is excellent not just for protective purposes but provides superb comfort, softness and naturally moisturizes and whitens our skin. We call this state-of-the-art innovation, Silk Protein Anti-Aging Technology.
For any enquiries, please contact us: info@silkskin.co
2. What is SERICIN?
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SERICIN is a protein created by Bombyx
mori (silkworms) in the production of silk
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Silk consists mainly of two proteins,
SERICIN and fibroin
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Fibroin being the structural center of the
silk
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SERICIN being the gum coating the fibres
and allowing them to stick to each other.
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Silk SERICIN has been used for over
3500 years by the world elite to
rejuvenate their hair and skin
3. SERICIN Applications
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Skin Creams (Anti-Aging)
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Hair Care (Moisturizer)
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Air Filters (Antimicrobial)
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Textiles (Antimicrobial)
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Edible Supplements
(Antioxidant)
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Serum for tissue culture
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Tissue Scaffold
4. Why SERICIN?
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SERICIN structure and the content of amino acids are
similar to the skin of human body, thus it is highly
compatible and absorbed easily with human skin (Padol
2012)
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SERICIN benefits:
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Moisturizing
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Anti-Aging
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Wound Healing
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Anti-Microbial
5. SERICIN Content
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SERICIN amino acid
composition that resemble
natural moisturizing factor
(NMF), which is naturally part
of our human make up.
6. SERICIN Moisturizing
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Decrease skin impedance
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Moisturizing of upper layer of skin
Increase in water holding
Increase hydroxyproline (protein binding capacity to stratum corneum)
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hydroproxyline important in stabilizing triple helical structure of collagen and connective tissue
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by restoration of amino acid
protein used to restore moisturization and skin tightening
Reduce excessive transepidermal water loss (TEWL)
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Occlusive effect preventing water loss from stratum corneum and allow water to accumulate
horny layer
Replacement of natural moisturizing factor (NMF) due to occurs by aging
7. SERICIN Moisturizing
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Skin treated with SERICIN
showed less flakes and
white ridges
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Decrease in flakes and
ridges of the skin reveals
the moisturization of the skin
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SERICIN forms a
moisturizing, semiocclusive, protective, anti
wrinkle film on the skin
surface imparting an
immediate, long lasting,
smooth, silky feeling.
9. Causes of Aging
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Extrinsic factors (also accelerate intrinsic factor)
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UV radiation causing
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Photo-aging
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Generate Reactive Oxygen Species (ROS)/ Oxidative Stress
leading to cell or tissue injury, they are responsible for many
diseases such as cancer
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over-production of elastase degrading elastin fiber (losing
elasticity and wrinkle formation)
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Sun exposure induces tyrosinase (Melanin
production/blackened peeled potato)
10. SERICIN Anti-Aging
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Reactive Oxygen species (ROS) scavenging/Antioxidant
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Due to high content of hydroxy amino acids (Serine & Threonine)
chelating trace elements such as copper and iron. Fan et al 2007
Evidenced by lipid peroxidation test by Kato et al 1997
Anti-tyrosinase (production of melanin e.g. blackening of sliced
potato)
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SERICIN contains flavonoids and carotenoids elements.
Chlapanidas et al 2013 confirmed SERICIN exhibits strong antityrosine properties.
Anti-elastase
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Chlapanidas et al 2013 concluded anti-elastase properties in
SERICIN that prevents loss of skin elasticity and wrinkle formation
11. SERICIN Anti-Aging
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UV protection
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SERICIN has suppressive activity against both chemical and
UV radiation by inhibiting epidermal oxidative stress,
suppression of COX-2 expression, and moisturizing effect.
Zhaorigetu et al 2003
Anti-apoptosis (programmed cell death)
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Western blotting test result indicates Sericin stimulated bcl-2
(an anti-apoptosis signal) by reducing the oxidative stress in
fibroblast. Kitisin et al 2013
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Blocking the caspase activity by reducing oxidative stress in
HaCat. Dash et al 2008
12. SERICIN Anti-Aging
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Zhaorigetu et al 2003
conduct acute 7 days
UVB radiation on mouse
skin
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Vehicle (control), BSA
(control), SIREN
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Rare 4-HNE (oxidative
stress marker) on
SERICIN treated skin
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Hardly observed COX-2
(marker of epidermal UVB
exposure) expression on
SERICIN treated Skin
13. SERICIN Anti-Aging
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Dash et al 2008 concluded anti-apoptotic effect
of SERICIN in UVB-irradiated cells is through the
blocking of caspace activities, possibly by
reducing oxidative stress in HaCat (Human Skin)
14. SERICIN Anti-Aging
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Dash et al 2007 test
SERICIN antioxidant against
H2O2.
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H2O2 as a model oxidant has
been well studied.
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Report conclude SERICIN is
an ideal molecule to prevent
oxidative stress.
15. SERICIN Wound Healing
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Methionine and cysteine promote cell growth and collagen synthesis.
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Aramwit et al 2007 concluded that SERICIN has good hydrophilic
properties, compatibility, and biodegradation.
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SERICIN treated wound had much smaller inflammatory reactions and
wound-size reduction greater than control.
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Mean time in days for 90% healing for SERICIN treated wound is much
lesser than control
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Histological examination shows SERICIN treated wound revealed
complete healing, no ulceration, no rash, and increase in collagen
compared to control, which showed some ulceration and
inflammatory.
18. SERICIN Antimicrobial
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Senakoon et al 2009 &
Rajendrana et al 2012
concluded that SERICIN
antibacterial property
against E. Coli and S.
Aureus
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E. Coli cell shrunk and
deep roughening of cell
surface
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S. Aureus cell exhibits
segregation, deformation,
reduced size and
shrinkage
19. SERICIN
Antimicrobial
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Jassim et al 2010 examined
SERICIN antibacterial
property by growing of
spores colonies and
examining tensile strength
of SERICIN treated and
untreated cotton fabric
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The average of untreated
fabric is 14.25 NIT, whereas
treated fabric is 96 NIT
(6.5X)