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Transfusion Therapy

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Shailendra Veerarajapura
Shailendra Veerarajapura

The document discusses guidelines and best practices for blood transfusion therapy. It covers indications for transfusions, compatibility testing, blood storage and components, complications of transfusions, and treatment of transfusion reactions. Specific topics include guidelines from ASA and other sources, cross matching versus type and screen, storage solutions, shelf life, hemolytic and non-hemolytic reactions and their treatment.

Wirtschaft & FinanzenGesundheit & Medizin
1 von 93
Transfusion Therapy Dr. Shailendra.V.L. Specialist in Anaesthesia, Al Bukariya General hospital.
Introduction ,[object Object],[object Object],[object Object],[object Object]
Indications for Transfusions ,[object Object],[object Object]
[object Object]
Indications for blood transfusion ,[object Object],[object Object],[object Object]
American College of Surgeons classes of Acute Hemorrhage
Clinical Judgment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Documentation ,[object Object],[object Object]
A.S.A practice guidelines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Habibi et al guidelines ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
[object Object]
Autologus blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Compatibility testing ,[object Object],[object Object],[object Object],[object Object]
 
Compatibility testing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cross match v/s Type & screen
Cross match ,[object Object]
Cross match ,[object Object],[object Object],[object Object],[object Object]
I phase – Immediate phase ,[object Object],[object Object],[object Object],[object Object]
II Phase – Incubation Phase ,[object Object],[object Object],[object Object],[object Object]
III Phase - Anti-globulin phase ,[object Object],[object Object],[object Object]
Antibody Screening ,[object Object],[object Object],[object Object]
Type & Screen ,[object Object],[object Object],[object Object],[object Object]
Maximal Surgical blood order schedule ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Maximum Surgical blood order schedule ,[object Object],[object Object],[object Object],[object Object],[object Object]
Is Cross Match really needed??? ,[object Object],[object Object],[object Object],[object Object]
Emergency Transfusion ,[object Object],[object Object],[object Object],[object Object]
Type specific, partially cross matched blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Type specific, uncross matched blood ,[object Object],[object Object],[object Object]
Type O, Rh - blood ,[object Object],[object Object],[object Object]
Storage of blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ACD solution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CPDA solution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CPDA solution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CPDA + Adsol ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CPDA + Nutricel ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Blood Shelf-life ,[object Object],[object Object],[object Object],[object Object],[object Object]
Blood storage ,[object Object],[object Object]
Properties of Stored Blood
Frozen storage ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Complications of blood transfusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Changes in O 2 transport ,[object Object],[object Object],[object Object],[object Object]
Effect on ODC curve
Coagulation problems ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dilutional thrombocytopenia ,[object Object],[object Object],[object Object],[object Object]
Platelet transfusion ,[object Object],[object Object],[object Object],[object Object]
Low Factors V & VIII ,[object Object],[object Object],[object Object],[object Object]
Citrate toxicity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Citrate Toxicity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Temperature ,[object Object],[object Object],[object Object],[object Object]
Temperature
Acid-Base abnormalities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Infusion of micro-aggregates ,[object Object],[object Object],[object Object],[object Object]
Transfusion reactions ,[object Object],[object Object],[object Object],[object Object]
Hemolytic transfusion reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hemolytic transfusion reaction
Haptoglobin – Hemoglobin complex ,[object Object],[object Object],[object Object]
 
Treatment ,[object Object],[object Object],[object Object],[object Object]
Lab investigations for hemolytic transfusion reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Effect on renal system ,[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]
Effect on Coagulation system ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Delayed hemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Non-hemolytic transfusion reactions ,[object Object],[object Object],[object Object],[object Object],[object Object]
Infectivity of Blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Post transfusion disease transmission ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Blood component therapy ,[object Object]
Blood Component therapy
Packed Red cells ,[object Object],[object Object],[object Object]
Packed RBC v/s Whole blood
Dilution of Packed RBCs ,[object Object],[object Object],[object Object]
Leukocyte reduced blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Fresh Frozen Plasma ,[object Object],[object Object],[object Object],[object Object]
Platelet concentrates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Indications for platelet concentrations ,[object Object],[object Object]
Fresh Frozen Plasma ,[object Object],[object Object],[object Object],[object Object]
ASA Task Force guidelines for FFP ,[object Object],[object Object],[object Object]
Cryoprecipitate ,[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma Protein ,[object Object],[object Object],[object Object],[object Object]
Plasma Volume Expanders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma Volume Expanders ,[object Object],[object Object],[object Object]
Haemaccel ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dextran - 40 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Dextran - 70 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Hydroxy-ethyl starch ,[object Object],[object Object],[object Object],[object Object]
Artificial blood ,[object Object],[object Object],[object Object]
Genetic engineering ,[object Object],[object Object],[object Object],[object Object]
Informed Consent ,[object Object],[object Object],[object Object]
Jehovah’s Witness ,[object Object],[object Object],[object Object],[object Object],[object Object]
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