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Pathophysiology DM.

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Shaikhani.
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Pathophysiology of Diabetes Melitus.

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Dr. Mohamed Al-Shekhani. Pathophysiology of DM.
Dual Metabolic Abnormalities in T2DM Excessive Hepatic Glucose Output Decreased Glucose Uptake Insulin DeficiencyInsulin Resistance Decreased Insulin Secretion Unrestrained Lipolysis
Treatment: • Diet/Exercise: both types • TIDM: Insulin. • T2DM: Oral hypoglycemic drugs +/- insulin.
Stepwise Management of T2 DM Insulin ± oral agents Oral combination Oral monotherapy Diet & exercise
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