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Evidence Based
   Medicine



 “Practical Guidelines for Management of
         the Difficult Airway”
Practical Guidelines
Practice guidelines are systematically
  developed recommendations that assist
  practitioner and patient in making
  decisions about health care.

American Society of Anesthesiologists
Anesthesiology 2013 (February); 118:251-70
Definitions
Difficult Airway:
The clinical situation in which a
 conventionally trained anesthesiologist
 experiences difficulty with facemask
 ventilation of the upper airway, difficulty
 with tracheal intubation or both
Sub Definitions
1. Difficult facemask or supraglottic
   airway (SGA):
   Difficulty in providing ventilation because
   of one or more problems.
        Inadequate mask or SGA seal
     Excessive gas leak
     Excessive resistance to ingress or egress of air
Sub Definitions
2. Difficult SGA placement:
    Requires multiple attempts, in presence
  or absence of tracheal pathology

3. Difficult Laryngoscopy:
    Not possible to visualise any portion of
  the vocal cords after multiple attempts at
  conventional laryngoscopy
Sub Definitions
4. Difficult Tracheal intubation:
   Requiring multiple attempts in the
  presence or absence of tracheal pathology



5. Failed intubation:
    Placement of ETT fails after multiple
  attempts.
Availability & Strength of
        Evidence
CATEGORY ‘A’
Level ‘1’ : Sufficient number of RCTs to conduct
  meta-analysis and meta-analytic findings


Level ‘2’ : Number of RCTs is insufficient to
  conduct viable meta-analysis


Level ‘3’ : Single RCT
CATEGORY ‘B’
Level ‘1’ : Observational comparisons between
  clinical interventions for a specified outcome
Level ‘2’ : Observational studies with associative
  statistics (relative risk, correlations)
Level ‘3’ : Noncomparative observational studies
  with descriptive statistics
  (frequencies, percentages)
Level ‘4’ : Case reports
Inferred findings are given a directional
designation of:
            Beneficial (B)
            Harmful (H)
            Equivocal (E)
GUIDELINES
STEP 1:
Evalution of the Airway
1. Evalution of the Airway
History:
• Association between several characters
  (age, obesity, OSA, H/O snoring) and difficult
  laryngoscopy (B2—H)
• Difficult intubation or extubation in patients with
  mediastinal masses (B3—H)
• Difficult laryngoscopy or intubation in variety of disease
  states e.g; ankylosis, tonsillar
  hypertrophy, osteoarthritis, pierre robin.   (B4—H)
1. Evalution of the Airway
Physical Examination:
• Association between anatomical features like features of
  head and neck and likelihood of difficult airway
  (B2—H)

• Radiography, CT scans, fluroscopy can identify variety of
  acquired and congenital features in patients with difficult
  airways   (B3—B)
1. Evalution of the Airway
Recommendations:
1. An airway history should be conducted with the intent to
   detect medical, surgical and anesthetic factors that may
   indicate presence of a difficult airway.

2. An airway physical examination should be conducted
   with the intent to detect physical characteristics leading
   to difficult airway.
1. Evalution of the Airway
STEP 2:
The Basic Preparation
2. Basic Preparation
• Preanesthetic preoxygenation by mask maintains higher
  O2 saturation values compared with room air controls
  (A3—B)

• 3mins preoxygenation maintains higher oxygen
  saturation values compared to 1min preoxygenation
  (A2—B)
2. Basic Preparation
• Oxygen saturation levels after preoxygenation are
  equivocal in preoxygenation for 3mins and fast track
  preoxygenation of 4 VC breaths in 30mins (A1—E)


• Lower frequencies of arterial desaturation during
  transport with supplemental oxygen to PACU than
  without oxygen   (A1—B)
2. Basic Preparation
Recommendations:
1. Inform the patient of special risks and procedures
   pertaining management of difficult airway.
2. Atleast one additional assistant should immediately be
   available to serve.
3. Always administer facemask preoxygenation.
4. Actively pursueopprtunities to deliver supplemental
   oxygen throughout the process.
5. Atleast one portable specialised unit for difficult airway
   management should be readily available.
2. Basic Preparation
STEP 3:
Strategy for Intubation
3. Strategy for Intubation
• A preplanned preinduction strategy should always be
  planned for every anesthetic.
           “Non invasive interventions”
a.   Awake intubation
b.   Video assisted laryngoscopy
c.   Intubating stylets or tube changers
d.   SGA for ventilation (LMA, Laryngeal tube)
e.   SGA for intubation (ILMA)
f.   Rigid larynogscopes
g.   Fiberoptic guided intubations
h.   Light wands
3. Strategy for Intubation
• Awake fiberoptic intubation is successful in 88-100%
  difficult airway cases (B3—B)
• Higher frequency of first attempt intubations with video
  assisted laryngoscope (A1—B)
• No time differences between VAL and conventional
  laryngoscopes (A1—E)
• No differences in degree of cervical spine deviation
  between VAL and conventional laryngoscopes
  (A3—B)
3. Strategy for Intubation
• LMA providing rescue ventilation in 94.1% who cannot
  be mask ventilated or intubated (B3—B)
• Laryngeal tubes provide adequate ventilation for 95% of
  patients with pharyngeal and laryngeal tumors
  (B4—B)
• When ILMA was used with semirigid collar, 3 of 10
  patients were successfully intubated (B3—B)
• Higher first attempt intubation for fibreoptic ILMA than
  standard fibreoptic intubation (A2—B)
3. Strategy for Intubation
• Laryngoscopes of alternate design may improve glottis
  visualisation (B3—B)
• Equivocal findings with rigid fiberscopes and rigid direct
  laryngoscopy for successful intubation and time to
  intubate (A2—E)
• ETCO2 confirms tracheal intubation in 88.5-100%
  patients (B3—B)
3. Strategy for Intubation
Recommendations:
1. Assessment of the likelihood and anticipated clinical
   impact of six basic problems.
    a. Difficulty with uncooperative patient
    b. Difficult mask ventilation
    c. Difficult SGA placement
    d. Difficult laryngoscopy
    e. Difficult Intubation
     f. Difficult surgical airway access
3. Strategy for Intubation
2. Consideration of the relative clinical merits and feasibility
   of four basic choices:
       a. Awake vs Intubation after GA
       b. Noninvasive vs Invasive techniques
       c. VAL as initial approach to intubation
       d. Preservation vs Ablation of spontaneous ventilation

3. Confirmation of tracheal intubation using capnography is
   mandatory requirement.
3. Strategy for Intubation
STEP 4:
Strategy for Extubation
4. Strategy for Extubation
Recommendations:
1. Consider merits of awake extubation vs extubation
   before return of consciousness.
2. An airway management plan should be implemented if
   the patient is unable to maintain ventilation.
3. Short term use of intubating bougie can serve as a
   guide for expedited reintubation
4. Strategy for Extubation
     Criteria for Awake Extubation
Subjective:
1.   Following commands
2.   No blood/secretions in hypopharynx
3.   Intact gag reflex
4.   Headlift/tongue blade for 5sec
5.   Adequate pain relief
6.   Minimal end tidal conc. of inhaled anesthetics
4. Strategy for Extubation
       Criteria for Awake Extubation
Objective:
1. Vital Capacity >10ml/kg
2. Tidal volume > 6ml/kg
3. Inspiratory intrathoracic pressure >
   -20cm H2O
4. Train of four T1/T4 > 0.7
5. Sustained tetanic contraction for 5sec
6. Alveolar to arterial PaO2 difference < 350mm
   Hg
STEP 5:
Follow-up Care
5. Follow-up Care
Recommendations:
1. A detailed description of the airway difficulties
   encountered.

2. A detailed description of the various airway
   management techniques used and indicate
   whether they played beneficial and detrimental
   role.
THE ALGORITHM
THANK YOU

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Evidence Based Medicine (Anesthesiology)

  • 1. Evidence Based Medicine “Practical Guidelines for Management of the Difficult Airway”
  • 2. Practical Guidelines Practice guidelines are systematically developed recommendations that assist practitioner and patient in making decisions about health care. American Society of Anesthesiologists Anesthesiology 2013 (February); 118:251-70
  • 3. Definitions Difficult Airway: The clinical situation in which a conventionally trained anesthesiologist experiences difficulty with facemask ventilation of the upper airway, difficulty with tracheal intubation or both
  • 4. Sub Definitions 1. Difficult facemask or supraglottic airway (SGA): Difficulty in providing ventilation because of one or more problems.  Inadequate mask or SGA seal  Excessive gas leak  Excessive resistance to ingress or egress of air
  • 5. Sub Definitions 2. Difficult SGA placement: Requires multiple attempts, in presence or absence of tracheal pathology 3. Difficult Laryngoscopy: Not possible to visualise any portion of the vocal cords after multiple attempts at conventional laryngoscopy
  • 6. Sub Definitions 4. Difficult Tracheal intubation: Requiring multiple attempts in the presence or absence of tracheal pathology 5. Failed intubation: Placement of ETT fails after multiple attempts.
  • 8. CATEGORY ‘A’ Level ‘1’ : Sufficient number of RCTs to conduct meta-analysis and meta-analytic findings Level ‘2’ : Number of RCTs is insufficient to conduct viable meta-analysis Level ‘3’ : Single RCT
  • 9. CATEGORY ‘B’ Level ‘1’ : Observational comparisons between clinical interventions for a specified outcome Level ‘2’ : Observational studies with associative statistics (relative risk, correlations) Level ‘3’ : Noncomparative observational studies with descriptive statistics (frequencies, percentages) Level ‘4’ : Case reports
  • 10. Inferred findings are given a directional designation of: Beneficial (B) Harmful (H) Equivocal (E)
  • 12. STEP 1: Evalution of the Airway
  • 13. 1. Evalution of the Airway History: • Association between several characters (age, obesity, OSA, H/O snoring) and difficult laryngoscopy (B2—H) • Difficult intubation or extubation in patients with mediastinal masses (B3—H) • Difficult laryngoscopy or intubation in variety of disease states e.g; ankylosis, tonsillar hypertrophy, osteoarthritis, pierre robin. (B4—H)
  • 14. 1. Evalution of the Airway Physical Examination: • Association between anatomical features like features of head and neck and likelihood of difficult airway (B2—H) • Radiography, CT scans, fluroscopy can identify variety of acquired and congenital features in patients with difficult airways (B3—B)
  • 15. 1. Evalution of the Airway Recommendations: 1. An airway history should be conducted with the intent to detect medical, surgical and anesthetic factors that may indicate presence of a difficult airway. 2. An airway physical examination should be conducted with the intent to detect physical characteristics leading to difficult airway.
  • 16. 1. Evalution of the Airway
  • 17. STEP 2: The Basic Preparation
  • 18. 2. Basic Preparation • Preanesthetic preoxygenation by mask maintains higher O2 saturation values compared with room air controls (A3—B) • 3mins preoxygenation maintains higher oxygen saturation values compared to 1min preoxygenation (A2—B)
  • 19. 2. Basic Preparation • Oxygen saturation levels after preoxygenation are equivocal in preoxygenation for 3mins and fast track preoxygenation of 4 VC breaths in 30mins (A1—E) • Lower frequencies of arterial desaturation during transport with supplemental oxygen to PACU than without oxygen (A1—B)
  • 20. 2. Basic Preparation Recommendations: 1. Inform the patient of special risks and procedures pertaining management of difficult airway. 2. Atleast one additional assistant should immediately be available to serve. 3. Always administer facemask preoxygenation. 4. Actively pursueopprtunities to deliver supplemental oxygen throughout the process. 5. Atleast one portable specialised unit for difficult airway management should be readily available.
  • 22. STEP 3: Strategy for Intubation
  • 23. 3. Strategy for Intubation • A preplanned preinduction strategy should always be planned for every anesthetic. “Non invasive interventions” a. Awake intubation b. Video assisted laryngoscopy c. Intubating stylets or tube changers d. SGA for ventilation (LMA, Laryngeal tube) e. SGA for intubation (ILMA) f. Rigid larynogscopes g. Fiberoptic guided intubations h. Light wands
  • 24. 3. Strategy for Intubation • Awake fiberoptic intubation is successful in 88-100% difficult airway cases (B3—B) • Higher frequency of first attempt intubations with video assisted laryngoscope (A1—B) • No time differences between VAL and conventional laryngoscopes (A1—E) • No differences in degree of cervical spine deviation between VAL and conventional laryngoscopes (A3—B)
  • 25. 3. Strategy for Intubation • LMA providing rescue ventilation in 94.1% who cannot be mask ventilated or intubated (B3—B) • Laryngeal tubes provide adequate ventilation for 95% of patients with pharyngeal and laryngeal tumors (B4—B) • When ILMA was used with semirigid collar, 3 of 10 patients were successfully intubated (B3—B) • Higher first attempt intubation for fibreoptic ILMA than standard fibreoptic intubation (A2—B)
  • 26. 3. Strategy for Intubation • Laryngoscopes of alternate design may improve glottis visualisation (B3—B) • Equivocal findings with rigid fiberscopes and rigid direct laryngoscopy for successful intubation and time to intubate (A2—E) • ETCO2 confirms tracheal intubation in 88.5-100% patients (B3—B)
  • 27. 3. Strategy for Intubation Recommendations: 1. Assessment of the likelihood and anticipated clinical impact of six basic problems. a. Difficulty with uncooperative patient b. Difficult mask ventilation c. Difficult SGA placement d. Difficult laryngoscopy e. Difficult Intubation f. Difficult surgical airway access
  • 28. 3. Strategy for Intubation 2. Consideration of the relative clinical merits and feasibility of four basic choices: a. Awake vs Intubation after GA b. Noninvasive vs Invasive techniques c. VAL as initial approach to intubation d. Preservation vs Ablation of spontaneous ventilation 3. Confirmation of tracheal intubation using capnography is mandatory requirement.
  • 29. 3. Strategy for Intubation
  • 30. STEP 4: Strategy for Extubation
  • 31. 4. Strategy for Extubation Recommendations: 1. Consider merits of awake extubation vs extubation before return of consciousness. 2. An airway management plan should be implemented if the patient is unable to maintain ventilation. 3. Short term use of intubating bougie can serve as a guide for expedited reintubation
  • 32. 4. Strategy for Extubation Criteria for Awake Extubation Subjective: 1. Following commands 2. No blood/secretions in hypopharynx 3. Intact gag reflex 4. Headlift/tongue blade for 5sec 5. Adequate pain relief 6. Minimal end tidal conc. of inhaled anesthetics
  • 33. 4. Strategy for Extubation Criteria for Awake Extubation Objective: 1. Vital Capacity >10ml/kg 2. Tidal volume > 6ml/kg 3. Inspiratory intrathoracic pressure > -20cm H2O 4. Train of four T1/T4 > 0.7 5. Sustained tetanic contraction for 5sec 6. Alveolar to arterial PaO2 difference < 350mm Hg
  • 35. 5. Follow-up Care Recommendations: 1. A detailed description of the airway difficulties encountered. 2. A detailed description of the various airway management techniques used and indicate whether they played beneficial and detrimental role.
  • 37.