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The Cell Cycle
Core Concepts ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Keywords ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Cell Cycle Roles of Cell Division ,[object Object],[object Object],[object Object]
The Cell Cycle Types of cell division ,[object Object],[object Object],[object Object],[object Object],[object Object]
The Cell Cycle Stages of the cell cycle
Important terms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Eukaryotic cell division ,[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],G 2  OF INTERPHASE PROPHASE PROMETAPHASE Centrosomes (with centriole pairs) Chromatin (duplicated) Early mitotic spindle Aster Centromere Fragments of nuclear envelope Kinetochore Nucleolus Nuclear envelope Plasma membrane Chromosome, consisting of two sister chromatids Kinetochore  microtubule  Nonkinetochore microtubules
[object Object],[object Object],[object Object],Centrosome at  one spindle pole Daughter  chromosomes METAPHASE ANAPHASE TELOPHASE AND CYTOKINESIS Spindle Metaphase plate Nucleolus forming Cleavage furrow Nuclear  envelope forming
[object Object],1 Prophase.  The chromatin is condensing.  The nucleolus is  beginning to  disappear. Although not  yet visible  in the micrograph,  the mitotic spindle is  staring to from. Prometaphase. We now see discrete chromosomes; each  consists of two  identical sister  chromatids. Later in prometaphase, the  nuclear envelop will  fragment. Metaphase.  The  spindle is complete, and the chromosomes, attached to microtubules at their kinetochores,  are all at the metaphase  plate. Anaphase.  The chromatids of each  chromosome have  separated, and the  daughter chromosomes are moving to the ends  of cell as their  kinetochore microtubles shorten. Telophase.  Daughter nuclei are forming.  Meanwhile, cytokinesis has started: The cell plate, which will  divided the cytoplasm  in two, is growing  toward the perimeter   of the parent cell. 2 3 4 5 Nucleus Nucleolus Chromosome Chromatin condensing
 
 
 
 
Regulation of the Cell Cycle ,[object Object],[object Object]
Restriction Point
Factors that control the cell cycle ,[object Object],[object Object],[object Object],[object Object]
Factors that control the cell cycle ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Factors that control the cell cycle ,[object Object],[object Object],[object Object],[object Object]
Factors that control the cell cycle ,[object Object],[object Object],[object Object]
Cancer – uncontrolled cell division ,[object Object],[object Object],[object Object]
Transformation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Causes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object]
Meiosis Reductional Division for Sexual Reproduction ,[object Object],[object Object],[object Object],[object Object],[object Object]
Meiosis in  Sexual Life Cycles ,[object Object],[object Object],[object Object]
Meiosis involves 2 stages of nuclear division ,[object Object],[object Object],[object Object],[object Object],[object Object]
Meiosis I is reductional cell division
Crossing-over  during Prophase I Exchange of segments between homologous pairs  ,[object Object],[object Object],[object Object],[object Object]
Independent assortment during Metaphase I
Meiosis II is equational cell division
How unique are you? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Gametogenesis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Spermatogenesis vs. Oogenesis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Spermatogenesis vs. Oogenesis Suspended in prophase I One oocyte / month Halted at metaphase II until fertilization 2N N N
OOGENESIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Questions: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Questions: ,[object Object],[object Object]
Errors in cell division    chromosomal aberrations ,[object Object],[object Object],[object Object],Meiosis I Nondisjunction Meiosis II Nondisjunction Gametes n +  1 n +  1 n   1 n –  1 n +  1 n – 1 n n Number of chromosomes Nondisjunction of homologous chromosomes in meiosis I Nondisjunction of sister chromatids in meiosis II (a) (b)
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Presentation 01 - The Cell Cycle