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  SciBite - From Molecule To Merger
            	
  
                     PHARMA & BIOTECH INTELLIGENCE SOLUTIONS
                                   Understanding The Therapeutic Landscape

    SciBite provides a powerful new approach to competitor intelligence and opportunity spotting
    within drug discovery. Our combination of advanced semantic text analysis and crowd-
    sourced, community trends provides you with a unique perspective on drugs, companies,
    targets and indications across patents, papers, clinical trials, grants, news and social media. All of
    this is live, updated continuously – you’ll never miss the next big thing!
    SciBite is essentially a large database of every recent article of relevance to drug discovery,
    accurately tagged with critical concepts. The system excels at:


    ¤ INFORMING SCIENTISTS & BUSINESS ANALYSTS

    SCIBITE.COM: Live Pharma Intelligence                        SCIBITE-PLUS: Coming Soon!

                           Keep up to date with the latest                      Cutting-edge analytics to
                           Drug Discovery trends.                               provide deep insight into
                           Literature, Patents, Grants,                         new therapeutic
                           Clinical Trials, Blogs, News,                        opportunities and
                           Tweets and more, all in one                          competitor activity. All from
                           place!                                               a single, web-based
                                                                                dashboard



    ¤ ENABLING INFORMATICIANS AND DATA MINERS

    THE SCIBITE API                                              “TERMITE” – TEXT MINING TOOL
                                                                                Class-leading text-mining
                           Access all of our data for your                      software and entity
                           own data mining. Find and                            recogniser. Semantic
                           mine new connections                                 markup of documents and
                           between drugs, companies,                            improve search engine
                           targets and indications.                             performance. Best in class
                                                                                thesauri.



    ¤ ENHANCING YOUR INTERNAL INFORMATION SYSTEMS

    SCIBITE WIDGETS                                              SCIBITE DATA

                          Embed live news into your own                         Access the full SciBite
                          applications, provide your                            dataset and connect the
                          scientists with instant, relevant                     rich information on the drug
                          updates. Simple, standards-                           discovery landscape into
                          based integration.                                    your internal network



    Contact us today to discuss how your organisation can keep track of new developments for the
    therapy areas and targets you care about. Take a look at: http://scibite.com.
    To contact us, please visit: http://scibite.com/talk.html



                                                                                                  Page 1 of 2
    © 2013 SciBite Limited. Registered In England & Wales No. 7778456
    Contact us via http://scibite.com/talk.html
       http://about.scibite.com    @Scibitely
  SciBite - From Molecule To Merger
            	
  
      ¤ SOURCES - SCANNED EVERY MINUTE, EVERY DAY
  No other system provides as broad coverage, in real time!
  Name                             Description
  MEDLINE                          Broad coverage of the biomedical published literature
  CLINICALTRIALS.GOV               Clinical trials database from the US NIH
  ISRCTN                           World-wide clinical trials database
  EUCTR                            European clinical trials register
  PATENTS                          WO, EP and US office life science and clinical patents
  GRANTS                           New grant awards in the US from the NIH
  NEWS                             Latest stories from thousands of government, industry and media websites
  SOCIAL                           Latest blog posts and tweets from key figures in the industry
  REAGENTS                         Biologically relevant chemicals



  ¤ MAJOR ENTITIES (CONCEPTS) COVERED
  Code                        Description                                                  Links To Public IDs?
  GENE                        Human gene/proteins                                          Yes (HGNC)
  PROTYP                      Protein Types (Families)                                     Yes (HGNC)
  INDICATION                  Human disease/indication                                     Yes (MeSH)
  COMPANY                     Pharma/Biotech companies                                     No (SciBite Proprietary)
  DRUG                        Known drugs (clinical, development & discovery)              Yes (ChEMBL)
  MIRNA                       MicroRNAs                                                    Yes (mirBase)
  MUTATION                    Protein Mutations                                            No (Not applicable)
  RESCODE                     Drug research codes                                          Yes (ChEMBL)
  BIOCHEM                     Biologically relevant chemicals                              Yes (MeSH)

  We use extensive synonym collections (‘thesauri”) to scan every article we see for mentions of critical drug discovery
  topics. Many of these are based on public sources, designed to facilitate integration with other data. However, they are
  extensively curated and validated to compensate for the many missing or ambiguous terms found in raw sources. Our
  Protein Family collection covers high-level molecule groups (such as ‘Interleukins’, ‘Cytokines’, ‘DNA Methylases’)
  capturing far more than traditional gene-centric approaches. We believe our thesauri give us, and potentially you, a clear
  advantage.


  ¤ WHAT CAN I DO WITH IT ALL?
  Our unparalleled combination of data mining and crowd-sourced social trends results in a powerful dataset for
  understanding the latest “hot” areas in drug discovery. By viewing our data in different ways you can understand
  competitor activity, look for new targets for an indication, find new biomarkers or biological approaches, monitor drug
  failures, identify trends and much more. Here are just some of the many ways to view our data:

                                                Heat maps differentiate novel
                                                and precedented approaches
                                                           Time
                                                                                 Target




    Trend Plots pick out
    topics peaking in activity                Publications/year for                             GEO tagging shows
                                              breast cancer targets
                                                                                                who’s working on what,
                                                                                                and where.


  ABOUT SCIBITE
  SciBite is led by scientists with many years experience analysing and acting on competitor intelligence within big
  pharma. We believe that our unique approach opens up access to this type of data to a wider audience and provides
  new opportunities to understand the ever-changing therapeutic landscape.


                                                                                                              Page 2 of 2
  © 2013 SciBite Limited. Registered In England & Wales No. 7778456
  Contact us via http://scibite.com/talk.html
     http://about.scibite.com    @Scibitely

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  • 1.   SciBite - From Molecule To Merger   PHARMA & BIOTECH INTELLIGENCE SOLUTIONS Understanding The Therapeutic Landscape SciBite provides a powerful new approach to competitor intelligence and opportunity spotting within drug discovery. Our combination of advanced semantic text analysis and crowd- sourced, community trends provides you with a unique perspective on drugs, companies, targets and indications across patents, papers, clinical trials, grants, news and social media. All of this is live, updated continuously – you’ll never miss the next big thing! SciBite is essentially a large database of every recent article of relevance to drug discovery, accurately tagged with critical concepts. The system excels at: ¤ INFORMING SCIENTISTS & BUSINESS ANALYSTS SCIBITE.COM: Live Pharma Intelligence SCIBITE-PLUS: Coming Soon! Keep up to date with the latest Cutting-edge analytics to Drug Discovery trends. provide deep insight into Literature, Patents, Grants, new therapeutic Clinical Trials, Blogs, News, opportunities and Tweets and more, all in one competitor activity. All from place! a single, web-based dashboard ¤ ENABLING INFORMATICIANS AND DATA MINERS THE SCIBITE API “TERMITE” – TEXT MINING TOOL Class-leading text-mining Access all of our data for your software and entity own data mining. Find and recogniser. Semantic mine new connections markup of documents and between drugs, companies, improve search engine targets and indications. performance. Best in class thesauri. ¤ ENHANCING YOUR INTERNAL INFORMATION SYSTEMS SCIBITE WIDGETS SCIBITE DATA Embed live news into your own Access the full SciBite applications, provide your dataset and connect the scientists with instant, relevant rich information on the drug updates. Simple, standards- discovery landscape into based integration. your internal network Contact us today to discuss how your organisation can keep track of new developments for the therapy areas and targets you care about. Take a look at: http://scibite.com. To contact us, please visit: http://scibite.com/talk.html Page 1 of 2 © 2013 SciBite Limited. Registered In England & Wales No. 7778456 Contact us via http://scibite.com/talk.html http://about.scibite.com @Scibitely
  • 2.   SciBite - From Molecule To Merger   ¤ SOURCES - SCANNED EVERY MINUTE, EVERY DAY No other system provides as broad coverage, in real time! Name Description MEDLINE Broad coverage of the biomedical published literature CLINICALTRIALS.GOV Clinical trials database from the US NIH ISRCTN World-wide clinical trials database EUCTR European clinical trials register PATENTS WO, EP and US office life science and clinical patents GRANTS New grant awards in the US from the NIH NEWS Latest stories from thousands of government, industry and media websites SOCIAL Latest blog posts and tweets from key figures in the industry REAGENTS Biologically relevant chemicals ¤ MAJOR ENTITIES (CONCEPTS) COVERED Code Description Links To Public IDs? GENE Human gene/proteins Yes (HGNC) PROTYP Protein Types (Families) Yes (HGNC) INDICATION Human disease/indication Yes (MeSH) COMPANY Pharma/Biotech companies No (SciBite Proprietary) DRUG Known drugs (clinical, development & discovery) Yes (ChEMBL) MIRNA MicroRNAs Yes (mirBase) MUTATION Protein Mutations No (Not applicable) RESCODE Drug research codes Yes (ChEMBL) BIOCHEM Biologically relevant chemicals Yes (MeSH) We use extensive synonym collections (‘thesauri”) to scan every article we see for mentions of critical drug discovery topics. Many of these are based on public sources, designed to facilitate integration with other data. However, they are extensively curated and validated to compensate for the many missing or ambiguous terms found in raw sources. Our Protein Family collection covers high-level molecule groups (such as ‘Interleukins’, ‘Cytokines’, ‘DNA Methylases’) capturing far more than traditional gene-centric approaches. We believe our thesauri give us, and potentially you, a clear advantage. ¤ WHAT CAN I DO WITH IT ALL? Our unparalleled combination of data mining and crowd-sourced social trends results in a powerful dataset for understanding the latest “hot” areas in drug discovery. By viewing our data in different ways you can understand competitor activity, look for new targets for an indication, find new biomarkers or biological approaches, monitor drug failures, identify trends and much more. Here are just some of the many ways to view our data: Heat maps differentiate novel and precedented approaches Time Target Trend Plots pick out topics peaking in activity Publications/year for GEO tagging shows breast cancer targets who’s working on what, and where. ABOUT SCIBITE SciBite is led by scientists with many years experience analysing and acting on competitor intelligence within big pharma. We believe that our unique approach opens up access to this type of data to a wider audience and provides new opportunities to understand the ever-changing therapeutic landscape. Page 2 of 2 © 2013 SciBite Limited. Registered In England & Wales No. 7778456 Contact us via http://scibite.com/talk.html http://about.scibite.com @Scibitely