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Partners	
  

Lean	
  Launchpad:	
  TherapeuFcs	
  

Value Propositions

	
  
Lean Launchpad: Digital Health
UCSF	
  Entrepreneurship	
  Center	
  
UCSF Entrepreneurship Center
November	
  5,	
  2013	
  
October 1, 2013
	
  

Karl	
  Handelsman	
  
Abhas Gupta, MD
Codon	
  Capital	
  	
  
Mohr Davidow Ventures
@abhasguptamd
Karl@codoncapital.com	
  

Weekly	
  Office	
  Hours:	
  4:30-­‐5:30	
  before	
  class	
  
Partnerships	
  and	
  OperaFons	
  
Next	
  
Week	
  

Value Propositions

This	
  
Lean Launchpad: Digital Health
Next	
  

Week	
  

Week	
  
UCSF Entrepreneurship Center
October 1, 2013

Abhas Gupta, MD
Who	
  are	
  the	
  key	
  partners	
  and	
  suppliers	
  needed	
  to	
  make	
  the	
  
Mohr Davidow Ventures
business	
  model	
  work?	
   @abhasguptamd
Value Propositions
Lean Launchpad: Digital Health
BiotechExamples	
  

UCSF Entrepreneurship Center
October 1, 2013

PARTNERS	
  
Abhas Gupta, MD
Mohr Davidow Ventures
@abhasguptamd
Keep	
  things	
  in	
  perspecFve	
  
Pharma	
  has	
  exisFng	
  products,	
  a	
  mulF	
  billion	
  dollar	
  research	
  budget,	
  a	
  pipeline	
  of	
  
products	
  at	
  every	
  stage.	
  	
  Your	
  Fny	
  company	
  has	
  an	
  idea	
  that	
  needs	
  proof	
  of	
  relevance.	
  

Value Propositions
Lean Launchpad: Digital Health
UCSF Entrepreneurship Center
October 1, 2013

Abhas Gupta, MD
Mohr Davidow Ventures
@abhasguptamd

“Big	
  things	
  have	
  small	
  beginnings”	
  
Types	
  of	
  Partnerships	
  
Joint	
  New	
  
Value Propositions
Strategic	
  
Business	
  
CoopeFFon	
  
Alliances	
   Launchpad: Digital Health
Lean
Development	
  
UCSF Entrepreneurship Center
Efforts	
  
October 1, 2013
Abhas
Key	
  Supplier	
   Gupta, MD
Joint	
  
Mohr Davidow Ventures
RelaFonships	
  
Ventures	
  
@abhasguptamd
Why	
  have	
  partners?	
  
•  More	
  efficient	
  use	
  of	
  capital	
  
•  Leverage	
  exisFng	
  capabiliFes	
  and	
  technologies	
  

Value Propositions

–  Build	
  vs	
  Buy	
  vs	
  Rent	
  	
  much	
  more	
  than	
  cost	
  	
  

Lean Launchpad: Digital Health

•  Time,	
  Focus,	
  Quality,	
  Talent,	
  ReputaFon,	
  SpecializaFon	
  
UCSF Entrepreneurship Center
October 1, 2013

•  Unique	
  customer	
  knowledge	
  or	
  experFse	
  
–  Plexxicon/Roche	
  (formulaFon/manufacturing)	
  
Abhas Gupta, MD
Mohr Davidow Ventures
@abhasguptamd
Roche	
  decides	
  to	
  re-­‐enter	
  anFbioFcs	
  
$40	
  million	
  upfront	
  and	
  up	
  to	
  $520	
  million	
  for	
  a	
  range	
  of	
  milestones	
  
covering	
  development	
  and	
  commercializaFon	
  work.	
  

Value Propositions

Lean Launchpad: Digital Health
UCSF Entrepreneurship Center
October 1, 2013

Abhas Gupta, MD
Mohr Davidow Ventures
@abhasguptamd
CooperaFon	
  
	
  

Value Propositions
Lean Launchpad: Digital Health

+	
  5	
  
UCSF
Undisclosed	
   Entrepreneurship Center
October 1, 2013

What	
  are	
  the	
  pharma	
  moFvaFons	
  to	
  cooperate?	
  	
  	
  
Why	
  is	
  this	
  good	
  for	
  MD
Abhas Gupta, Ablexis?	
  
What	
  about	
  c Ventures
Mohr Davidowontrol?	
  
@abhasguptamd
Did	
  Ablexis	
  cap	
  their	
  upside?	
  
	
  

	
  	
  
	
  
	
  

	
  

	
  	
  
 
H3	
  Biomedicine:	
  coordinaFon	
  of	
  
mulFple	
  partnerships	
  
$200M	
  

Value Propositions
idate	
  
ND	
  Cand
cial:I
Pre-­‐Clini

Conduct	
  
Lean Launchpad: Digital Health Clinical	
  Trials	
  
Upfront	
  and	
  milestones	
  	
  

UCSF Entrepreneurship Center
October 1, 2013

Abhas Gupta, MD
$6.7M	
  grant	
  
Mohr Davidow Ventures
@abhasguptamd

Novel	
  cancer	
  target	
  discovery/validaFon	
  

Cancer	
  	
  BioinformaFcs	
  
Cancer	
  Genome	
  Atlas	
  
Value Propositions
Lean Launchpad: Digital Health
UCSF Entrepreneurship Center
October 1, 2013
My	
  Contact:	
  Put	
  LLP	
  in	
  Subject	
  Line	
  for	
  extra	
  points	
  	
  

KARL@CODONCAPITAL.COM	
  
Abhas Gupta, MD
Mohr Davidow Ventures
@abhasguptamd

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UCSF LIfe Sciences: Week 6 Therapeutics Partners

  • 1. Partners   Lean  Launchpad:  TherapeuFcs   Value Propositions   Lean Launchpad: Digital Health UCSF  Entrepreneurship  Center   UCSF Entrepreneurship Center November  5,  2013   October 1, 2013   Karl  Handelsman   Abhas Gupta, MD Codon  Capital     Mohr Davidow Ventures @abhasguptamd Karl@codoncapital.com   Weekly  Office  Hours:  4:30-­‐5:30  before  class  
  • 2. Partnerships  and  OperaFons   Next   Week   Value Propositions This   Lean Launchpad: Digital Health Next   Week   Week   UCSF Entrepreneurship Center October 1, 2013 Abhas Gupta, MD Who  are  the  key  partners  and  suppliers  needed  to  make  the   Mohr Davidow Ventures business  model  work?   @abhasguptamd
  • 3. Value Propositions Lean Launchpad: Digital Health BiotechExamples   UCSF Entrepreneurship Center October 1, 2013 PARTNERS   Abhas Gupta, MD Mohr Davidow Ventures @abhasguptamd
  • 4. Keep  things  in  perspecFve   Pharma  has  exisFng  products,  a  mulF  billion  dollar  research  budget,  a  pipeline  of   products  at  every  stage.    Your  Fny  company  has  an  idea  that  needs  proof  of  relevance.   Value Propositions Lean Launchpad: Digital Health UCSF Entrepreneurship Center October 1, 2013 Abhas Gupta, MD Mohr Davidow Ventures @abhasguptamd “Big  things  have  small  beginnings”  
  • 5. Types  of  Partnerships   Joint  New   Value Propositions Strategic   Business   CoopeFFon   Alliances   Launchpad: Digital Health Lean Development   UCSF Entrepreneurship Center Efforts   October 1, 2013 Abhas Key  Supplier   Gupta, MD Joint   Mohr Davidow Ventures RelaFonships   Ventures   @abhasguptamd
  • 6. Why  have  partners?   •  More  efficient  use  of  capital   •  Leverage  exisFng  capabiliFes  and  technologies   Value Propositions –  Build  vs  Buy  vs  Rent    much  more  than  cost     Lean Launchpad: Digital Health •  Time,  Focus,  Quality,  Talent,  ReputaFon,  SpecializaFon   UCSF Entrepreneurship Center October 1, 2013 •  Unique  customer  knowledge  or  experFse   –  Plexxicon/Roche  (formulaFon/manufacturing)   Abhas Gupta, MD Mohr Davidow Ventures @abhasguptamd
  • 7. Roche  decides  to  re-­‐enter  anFbioFcs   $40  million  upfront  and  up  to  $520  million  for  a  range  of  milestones   covering  development  and  commercializaFon  work.   Value Propositions Lean Launchpad: Digital Health UCSF Entrepreneurship Center October 1, 2013 Abhas Gupta, MD Mohr Davidow Ventures @abhasguptamd
  • 8. CooperaFon     Value Propositions Lean Launchpad: Digital Health +  5   UCSF Undisclosed   Entrepreneurship Center October 1, 2013 What  are  the  pharma  moFvaFons  to  cooperate?       Why  is  this  good  for  MD Abhas Gupta, Ablexis?   What  about  c Ventures Mohr Davidowontrol?   @abhasguptamd Did  Ablexis  cap  their  upside?                  
  • 9.   H3  Biomedicine:  coordinaFon  of   mulFple  partnerships   $200M   Value Propositions idate   ND  Cand cial:I Pre-­‐Clini Conduct   Lean Launchpad: Digital Health Clinical  Trials   Upfront  and  milestones     UCSF Entrepreneurship Center October 1, 2013 Abhas Gupta, MD $6.7M  grant   Mohr Davidow Ventures @abhasguptamd Novel  cancer  target  discovery/validaFon   Cancer    BioinformaFcs   Cancer  Genome  Atlas  
  • 10. Value Propositions Lean Launchpad: Digital Health UCSF Entrepreneurship Center October 1, 2013 My  Contact:  Put  LLP  in  Subject  Line  for  extra  points     KARL@CODONCAPITAL.COM   Abhas Gupta, MD Mohr Davidow Ventures @abhasguptamd