Physiology of Smooth Muscles -Mechanics of contraction and relaxation
Leaflet international workshop autism august 2010 final
1. molecular biology of neurodevelopmental disorders, with particular emphasis on fragile
Call for Poster X syndrome, the leading heritable form of mental retardation. Since joining the Davis
faculty, Dr. Hagerman has expanded his research efforts to include investigations of the nd
Theme : Update on management and treatment of MR, Autism, and
other Neurodevelopmental Disorder
underlying biochemical and genetic causes of autism.
Louise Gane, M.Sc
2 International Seminar and
Guidelines for submission of abstracts:
1. A b s t r a c t s m a y b e s u b m i t t e d o n l y v i a e m a i l :
She is Senior Genetic Associate at the M.I.N.D. Institute. In 1991,
she joined the team led by Dr. Hagerman at the Fragile X Workshop on Fragile-X, Autism
mrautism.undip@gmail.com Research and Treatment Center in Denver, Colorado as a
2. All abstracts must be submitted and written in English, maximum 250
words.
genetic counsellor. Under the directorship of Dr. Randi
Hagerman, Louise is now located at the UC Davis M.I.N.D. and Related Disorders
Institute working as a Genetic Counsellor and Assistant to the
3. Poster size: 90 x 120 cm (portrait) Director. She is involved in counselling patients with Fragile X
4. Abstracts must contain original material neither published nor syndrome and their family members. In her role Louise helps
presented elsewhere and must be approved by all contributing families deal with and understand the diagnosis, assessing genetic risk, and explaining
authors. reproductive options
5. Please structure your abstract using the following headings:
Introduction, Objectives, Methods, Results, Conclusion. Committee
6. Abstracts will be subject to blind peer reviewers.
Patron
7. Deadline of abstract submission : July 7, 2010 and two weeks later, Rector of Diponegoro University
authors will be notified of acceptance by email. Director of Dr Kariadi Hospital Semarang
8. Authors with accepted abstracts are entitled to register as Dean, Faculty of Medicine Diponegoro University (FMDU)
participants. Vice Rector for Development and Cooperation
9. Poster should be displayed by the participants in person one hour Vice Dean for Finance
prior the registration and should be standby during the Poster Advisor of Center for Biomedical Research (Cebior)
Session. Chair
Prof. Sultana MH Faradz, MD, PhD
Co-Chair
International Speakers Fitri Hartanto, MD (Pediatrician)
Prof. Randi J. Hagerman, MD Secretary
Professor Randi Hagerman is a Developmental and Behavioral Neni Susilaningsih, MD, Msc
Pediatrician and the Medical Director of the M.I.N.D. Institute at Muflihatul Muniroh, MD, MSc
UC Davis. She is internationally recognized as both a clinician Secretariat
and researcher in the fragile X field. Professor Hagerman Nani Maharani, MD, Msc, Ardina Aprilani, S.Sos
received her M.D. from Stanford University where she also Treasurer
carried out her Pediatric residency. She completed a
Ratna Damma Purnawati, MD, Msc, Annastasia Ediati, S.Psi, MSc, Psi
Fellowship in Learning and Disabilities and Ambulatory
Scientific Committee
Asri Purwanti, MD (Pediatrician), Alifiani Hikmah Putranti, MD (Pediatrician),
Pediatrics at UC San Diego and, subsequently, spent the next 20 years from 1980 to 2000 at
the University of Colorado where she headed Developmental and Behavioral Pediatrics. Dani Rahmawati, MD (Neurologist), Alifiati Fitrikasari, MD (Psychiatrist),
She co-founded the National Fragile X Foundation in 1984 in Colorado and developed a Hexanto, MD (Neurologist), Eko Adhi Pangarsa, MD (Internist),
th
th
world-renowned fragile X research and treatment center. In 2000, Professor Hagerman
moved to UC Davis to be the Medical Director of the M.I.N.D. Institute. Dr. Hagerman and
Yetty Movieta Nency, MD (Pediatrician), Farmaditya EP Mundhofir, MD, Msc,
Maria Belladona, MD, M. Mexitalia Setiawati, MD, PhD (Pediatrician), Semarang, 7 August 2010
her team discovered the Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) which is a Rudi Handoyo, MD (Medical rehabilitation)
neurological disorder that affects older carriers of fragile X. Talk show Committee
Prof. Paul J. Hagerman, MD, PhD Fitri Hartanto, MD (Pediatrician), Niken Puruhita, MD, MSc (Nutritionist) Diponegoro University
He received both his M.D. and Ph.D. degrees from Stanford Agustini Utari, MD, MSc (Pediatrician), Costrie Ganes, SPsi in collaboration with:
University School of Medicine in 1977. This was followed by a Audiovisual & Documentation
three year Leukemia Society Fellowship at UCSD, where he Ahmad Zulfa Juniarto, MD, MSc (Andrologist) Medical Investigation of
began his studies of nucleic acid structure. He joined the Accomodation Neurodevelopmental Disorders
University of Colorado in 1980, where he remained prior to Aris Catur, MD (Neurologist)
joining the UC Davis faculty. Hagerman is currently on the Translator
(MIND) Institute, UC Davis
scientific advisory board of the Muscular Dystrophy
Widagdo, S.Ked
Association, and recently shifted toward the study of the
2. comprises also a talk show session, which will present some
Background cases of autism and ID patients. Program
Fragile-X syndrome (FXS) is the most common form
of inherited intellectual disabilities (ID). The clinical signs Purpose Saturday, August 7, 2010
are intellectual disabilities, hyperactive, autism, 07.30 - 08.00 Registration
To disseminate recent advances and treatments in the field
psychoneurologic disorders, and macroorchidism (testes 08.00 - 08.15 Opening Speech by :
of Fragile X syndrome, Autism and related disorders from
enlargement) in male. The common affected is in males; 1. Chairperson
the expert scientist to the parents and people who are
however, carrier female could have a mild intellectual interested in those field. 2. Rector of Diponegoro University
disability such as learning difficulties, without other 08.15 – 08.30 Future and challenges of Autism Center in
symptoms. Some clinically normal males (Normal Indonesia
Transmitting Males) are known to carry and transmit the Venue
Prof. Susilo Wibowo, MD, PhD, Andrologist
fragile X mutation to their daughter. In advance age, carriers Patra Convention Hotel
08.30 - 08.50 Fragile X syndrome in Indonesia
of FXS could develop Fragile-X-Associated Tremor Ataxia Jl. Sisingamangaraja, Semarang
(FXTAS), a neurodegenerative disorder.
Prof. Sultana MH Faradz, MD, PhD
Autistic spectrum disorder (ASD) involves Participants 08.50 – 09.20 RNA toxicity and FXTAS in Fragile-X
developmental abnormalities in reciprocal social premutation carriers
This workshop is suited for parents, students Prof. Paul Hagerman, MD, PhD
interaction, communication, and repetitive behavior. Some (undergraduates and postgraduates), medical scientists,
genetic disorders associated with autism for example: clinicians, nutritionist, psychologist, and people who are 09.20 - 09.50 Clinical Aspect of Autism and Its
Down Syndrome (DS), FXS and microdeletion chromosomal interested. The number of participants is limited to 300 Management
disorders such as Angelman syndrome, Prader Willi people. Melly Budhiman, MD, Child Psychiatrist
syndrome etc. The information gap between experts and 09.50 – 10.20 Autism and Fragile X syndrome: Advances
parents could be a serious problem for patient Date in Targeted treatments
management. Recently many studies in this field have been Prof. Randi J. Hagerman, MD, PhD
developed to find the newest and effective treatment and August, 7th 2010
management. 10.20 – 10.35 Discussion
Advances in understanding the neurobiology of FXS Registration Fee 10.50 – 11.05 Minocycline study in Fragile X syndrome
have led to new targeted treatments. The most remarkable UNDIP staff Free and Autism
are the metabotropic glutamate receptor 5 (mGluR5) Non UNDIP staff Agustini Utari, MD, M.Sc, Pediatrician
antagonists. The mGluR5 antagonists have been studied in Physician (Specialist) Rp. 500.000,- 11.05 – 11.45 Psychopharmacological intervention in
animal models of fragile X and have been shown to have a General Practitioner Rp. 250.000,- Autism and Fragile X syndrome
beneficial effect on seizures, cognition, and behavior. Public Rp. 250.000,- Prof. Randi J. Hagerman, MD, PhD
Another recent advances in FXS treatment is Minocycline. Discount 50% for autism parents, FMDU students and 11.45 – 12.10 Genetic Counseling in Fragile X syndrome
Studies in animal models suggest that minocycline is not alumni of genetic counselling master program UNDIP.
and Autism
only useful as an antibiotic but may also has potential as
neuroprotective agent. Those advancements in FXS
Information and registration Louise Gane, M.Sc
Wiwik / Dina (Center for Biomedical Research) 12.10 – 12.25 Discussion
treatment in patients will be discussed in this workshop.
GSG 2nd Floor Jl. Dr. Sutomo 14 Semarang 12.25 - 13.10 Lunch and poster session
Within the framework of long collaboration with the
Tel: +62-24-8412311 Fax: +62-24-8454714
Medical Investigation of Neurodevelopmental Disorders 13.10 – 15.20 Talk show (patients, parents and
HP:+62-81-931980014
(MIND) Institute, UC Davis, USA; Faculty of Medicine experts)
e-mail : molcytogen@yahoo.com,
Diponegoro University (FMDU) Semarang Indonesia will 15.20 - 15.40 Best posters announcement and
genetikaundip@indosat.net.id
organize a 2nd International workshop on Fragile X Closing ceremony
website : www.cebior.co.cc
Syndrome, Autism and Related Disorders. This workshop