This document discusses GROMACS, a software package for molecular dynamics simulations. GROMACS can simulate hundreds to millions of particles and is primarily used for biochemical molecules like proteins, lipids and nucleic acids. It contains tools like mdrun for basic molecular dynamics calculations and mpimdrun, which executes mdrun in parallel across multiple computers. Running GROMACS simulations can take 16-48 hours depending on the system, and using more computational cores allows faster simulations. The document proposes making GROMACS available on the GISELA e-infrastructure to allow researchers to perform molecular dynamics simulations without needing local computational resources.