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A Case of Unsteadiness and Limb Weakness Dr Richard McCrory CT2 Medicine 9 th  March 2011
Case Presentation: Mrs E.W. (1) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mrs E.W. (2) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Initial assessment 27/8/10 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Initial Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
But there’s more
 ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
But there’s (still) more
 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
CT Chest/Abdo/Pelvis 19/10/10 ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Final Diagnosis –  Paraneoplastic Cerebellar Degeneration secondary to Primary B-Cell Lymphoma of the Breast
The Cerebellum – A Brief Overview of Functional Anatomy ,[object Object],[object Object],[object Object]
Paraneoplastic Neurological Syndromes ,[object Object],[object Object]
Paraneoplastic cerebellar degeneration (PCD) ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Features of PCD ,[object Object],[object Object]
A Large Diagnostic Differential ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Findings  not  Consistent with   paraneoplastic cerebellar degeneration  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Prognosis ,[object Object],[object Object],[object Object]
Take Home Messages ,[object Object],[object Object]
 

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A case of unsteadiness and limb weakness

  • 1. A Case of Unsteadiness and Limb Weakness Dr Richard McCrory CT2 Medicine 9 th March 2011
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  • 15. Final Diagnosis – Paraneoplastic Cerebellar Degeneration secondary to Primary B-Cell Lymphoma of the Breast
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