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Wide QRS Tachycardia

            MSN PAVAN KUMAR
Wide complex tachycardia


 Definitions
 Causes
 Features for differentiation
 Diagnostic approach/algorithms
Wide complex tachycardia


Definition :
 A rhythm with QRS duration ≄ 120 ms and heart rate > 100/min.
 Sustained vs non sustained
Wide complex tachycardia
Causes :
    Regular :
    1. Ventricular tachycardia(80% of WCT)
    2. Any SVT with aberrancy (2nd MC WCT)
    3. Any SVT with BBB
    4. Any SVT with delayed conduction d/t drugs and electrolytes
       a. Class IA,IC ; hyperkalemia.
    5. Antidromic AVRT(1-5%)
    6. Pacemaker mediated rhythm
    Irregular :
    1. AF with conduction on preexcitation pathway.
    2. Any irregular SVT with aberrancy , BBB .
    3. VT in the 1st 30 sec , pts on anti arrythmitic drugs – cycle length
       varibility.
Wide complex tachycardia
Features for differentiation :

  Pacemaker rhythm(<1% of WCT)
 1. History and physical examination
 2. ECG:
   a. Stimulus artefact
   b. LBBB with left superior axis(if RV apical pacing) , various
      combinations ( biventricular pacing)
Wide complex tachycardia
Features for differentiation :

  VT vs Preexcited tachycardia
  ‱VT
     – Predominantly negative QRS complexes in V4-V6
     – Presence of a QR complex in one or more leads V2-V6
     – More QRS complex than P
  ‱75% sensitivity & 100% specificity for VT (Stierer et al)
Wide complex tachycardia
 Features for differentiation :
 History and physical examination:
1. H/o heart disease – previous MI , angina , CHF – have a PPA of 95%
   for diagnosing VT
2. Pts with VT are older than SVT (> 35 yrs)
3. SVT-A often have h/o previous episode(>3years)
4. Pts with SVT-A are hemodynamically stable.
5. Examination for AV dissociation
   a. Cannon A waves in JVP
   b. Variable S1 intensity
   c. Variation in SBP unrelated to respiration.
6. Termination of WCT with physical manoeuvres and medications
Wide complex tachycardia
 Features for differentiation by ECG :
1. QRS duration
2. QRS axis
3. Concordant pattern
4. Precordial RS duration.
5. Morphological criteria - RBBB , LBBB , ambiguous chest lead pattern
6. Q wave presence
7. AV dissociation
8. Baseline QRS prolongation – QRS duration , QRS configuration.
9. aVR changes.
10.Lead II R-wave-peak-time (RWPT) criterion .
Wide complex tachycardia
1. QRS duration :
 > 160 ms with LBBB , >140 ms with RBBB - VT
 Wellens et al . Showed that 69% of VT had QRS duration of
   >140ms and none of SVT-A showed QRS duration of >140ms.
 Exceptions:
 a. Anti arrythmitic drugs non specifically prolong QRS duration.
 b. Pts with structurally normal heart may have VT with QRS
     duration of 120-140ms.(<140ms in12% , < 120 ms in 4%)
 c. QRS duration also depend site of origin of VT , septal VT

                QRS duration has sensitivity of 70%
Wide complex tachycardia
Wide complex tachycardia
2.   QRS axis :
    Frontal plane axis of -90 to +180 --- VT
    Shift in QRS axis of more than 40 from baseline --- VT(less
     specific)
    RBBB with LAD, LBBB with RAD --- VT.
    LAFB (-30 to -90) ,
     LPFB (+110 to150) and
     RBBB (normal axis).
Wide complex tachycardia
3.Concordant QRS in chest leads:
 Concordant QRS in chest leads is diagnostic of VT uncommon in
  SVT-A.
 Exceptions:
  Positive concordance (ventricular activation begins left
    posteriorly) seen in VT originating in Lt post wall or SVT using a
    left posterior accessory pathway for AV conduction.
  If no additional criteria for WPW are absent don’t consider it
    because of low incidence(<6%)


                    Specificity of 90%, Sensitivity of 20%
Wide complex tachycardia
Wide complex tachycardia
3.Concordant QRS in limb leads :
 The presence of predominantly negative QRS complexes in leads
  1,2,3 is suggestive of VT
 This is another way to describe right superior axis
 Similar to RS axis it is considered as highly specific for VT
Wide complex tachycardia
4.Pericardial RS duration criteria :
 If concordant QRS complexes are absent i.e with RS complex
  onset of R wave to nadir of S wave > 100 ms.




      Sensitivity – 66%
      Specificity - 98%
Wide complex tachycardia
5.RBBB – V1 :
 rSr , rSR , rR , rsr patterns consistent with SVT-A
 R , R>30ms with any negative QRS , qR --- VT
 This is because right ventricle doesn’t participate in initial QRS




     Sensitivity – 30-80%
     Specificity - 84-95%
Wide complex tachycardia
5.RBBB – V6 :
 qRs , Rs , RS with R/S >1 --- SVT –A
 R , QR , QS , RS with R/S < 1 --- VT




      Sensitivity – 30-60%
     Specificity - 80-100%
Wide complex tachycardia
5.   LBBB – V1,V6:

 Sensitivity – 100%              Sensitivity – 17%
 Specificity - 89%              Specificity - 100%
Wide complex tachycardia


5.Ambiguous chest lead pattern:
 W and M pattern in V1 have been classified as LBBB & RBBB
 Because they are ambiguous in this way, they are unlikely to
  represent typical aberration and are highly specific for VT.
 Sensitivity of 60-80% , specificity of 90-95%.
Wide complex tachycardia
6. Q wave presence :
 Q during WCT --- suggest old MI --- VT most likely.
 In general pts with post MI VT maintain Q wave during WCT that
   are present during baseline in the same lead.
 Exceptions :
 1. Pts with DCMP will have Q wave during VT that are not present
     during baseline.
 2. PSEUDO Q wave with retrograde p wave deforming QRS can
     be seen in SVT-A
 3. Preexcited tachycardia with posterior AV connection can have Q
     wave in inferior leads
Wide complex tachycardia
7.  AV dissociation :
 The most specific ECG finding for VT .
 Clues for AV dissociation:
 1. Clinically by cannon A waves , variable intensity of S1 , Variation
      in SBP unrelated to respiration.
 2.    AV dissociation
 3. AV ratio of less than 1
 4. 2:1 VA block(d/t retrograde conduction)
 5. Variation in QRS amplitude during WCT
 6. Fusion & capture beats
 7. Recording separate atrial electro gram
      (oesophageal/transvenous)
 8. Echo (evaluating RA contraction in relation to ventricular)
Wide complex tachycardia
7.   AV dissociation :

                                    V rate = 215/mt
                                    A rate = 125/mt
                                    A/V =0.58
Wide complex tachycardia
7.   AV dissociation :




     VT with retrograde 2:1 VA conduction (seen in 15-20% of VT)
Wide complex tachycardia
7.     AV dissociation :




      Variation in amplitude of QRS during WCT
     1. Scalar summation of P wave with QRS
     2. Variable ventricular filling in the presence of AVD
      Presence of multiple WCT configuration has a sensitivity of 55%
       for diagnosing VT
Wide complex tachycardia
7.   AV dissociation :




  The QRS complex is prolonged, and the R-R interval is regular
  except for occasional capture beats (C) that have a normal contour
  and are slightly premature. Complexes intermediate in contour
  represent fusion beats (F).
  Thus, even though atrial activity is not clearly apparent,
  atrioventricular dissociation is present during ventricular
  tachycardia and produces intermittent capture and fusion beats
Wide complex tachycardia
7.   AV dissociation :
Wide complex tachycardia
7.      AV dissociation :
      Caveats while using AVD:
     1. Low sensitivity (20-50%) is d/t fast heart rates , inadequate
        duration of recording , observer inexperience.
     2. 30% of pts , especially VT with low V rate , have 1:1 VA
        conduction – differentiate by vagal maneuvers , adnosine.
     3. AF and VT co exist AVD cannot be diagnosed .




                           Sensitivity – 20-50%
                            Specificity – 98%
Wide complex tachycardia
8.     Base line QRS prolongation:
a.     Pt with baseline QRS rhythm and WCT QRS different – VT
1.     QRS during VT is narrower than baseline rhythm
2.     Contra lateral BBB in baseline rhythm and during WCT
3.     AV dissociation
4.     Rarely other findings may be useful like precordial concordance ,
       north-west axis , monophasic R wave in V1


     Pts with BBRT     Impulse originates in RBB     Travels through LBB

                                               Have typical features of LBBB
Wide complex tachycardia
9.   aVR changes :
1.   Presence of initial ‘r’ wave in aVR
2.   Presence of initial ‘r’ or ‘q’ wave of > 40ms duration
3.   Presence of notch in descending limb of negative onset and
     predominantly negative QRS
4.   Vi/Vt ≀ 1
        All the above features are indicative of VT


                       Sensitivity – 96.7%
                        Specificity – 99%
Wide complex tachycardia
  9.                                          aVR changes : Initial ‘r’
                                              wave in aVR
                                         During SVT with aberrancy ,
                                         initial septal activation and main
                                         ventricular activation are
                                         directed away from lead aVR
                                          negative QRS complex



Exceptions :
1. Inferior MI- initial r wave (rS complex) during NSR or SVT
2. VT originating from base of heart may not have initial r wave
Wide complex tachycardia
9.   aVR changes :
Wide complex tachycardia
 9.   aVR changes : Vi/Vt ≀ 1
Vi = voltage in the initial 40ms of QRS
Vt = voltage in the terminal 40ms of QRS
In SVT-A only one portion is bundle branch is blocked --- so the
 initial portion of QRS is rapid compared to terminal portion.
In VT slow muscle to muscle spread of impulse causes slower
 voltage changes through out QRS complex
Can be applied to any lead
The vi/vt was > 1 (signifying supraventricular origin) in 88%
 tracings with LBBB pattern, in 98% with RBBB pattern, and
 90% with nonspecific IVCD.
Wide complex tachycardia
9.   aVR changes : Vi/Vt ≀ 1
Wide complex tachycardia
10. Lead II R-wave-peak-time (RWPT) criterion : Pavas criteria

                                      RWPT > or =50 ms at DII is a
                                      simple and highly sensitive
                                      criterion that discriminates VT
                                      from SVT in patients with wide
                                      QRS complex tachycardia.


                                                  Sensitivity and
                                                specificity of 97%



                               Heart Rhythm. 2010 Jul;7(7):922-6. Epub 2010 Mar 4.
Wide complex tachycardia
 Diagnostic approach/algorithms
  1.   Wellens(1978) , Akhtar(1988) ,
  2.   Brugada(1991)
  3.   Griffith(1994)
  4.   Bayesian(1995)
  5.   aVR algorithms(2007)
  6.   lead II R-wave-peak-time (RWPT) criterion(2010)
  7.   Combined .
Wide complex tachycardia
Diagnostic approach/algorithms




     WELLENS CRITERIA            AKHTAR CRITERIA
Wide complex tachycardia
Diagnostic approach/algorithms   BRUGADA CRITERIA




                                             Sensitivity – 98.7%
                                             Specificity – 96.5%




                                 Brugada P, Brugada Jet al.A new approach to the
                                 DD of a regular tachycardia with a wide QRS
                                 complex. Circulation. 1991;83:1649-16595
Wide complex tachycardia
Diagnostic approach/algorithms                   GRIFFITH CRITERIA
                                 WCT




           NO                                                       YES

                       VT         YES
                                                     INDEPENDENT P WAVES

   Sensitivity – 95%
                                 Griffith MJ,Garratt Ci,et VT as default diagnosis in
   Specificity – 64%             broad complex tachycardia. Lancet 1994 feb
Wide complex tachycardia
 Diagnostic approach/algorithms                 BAYESIAN CRITERIA

CRITERIA            LR            V WAVE IN LBBB
QRS WIDTH                              r > 40MS          50
     =140MS         0.31               NOTCH IN ‘S’      50
     140-160MS      0.48               R-S > 60MS        50
     > 160MS        22.86               NONE             0.13
QRS AXIS                          INTRINSICOID IN V6
     NW AXIS        7.86               = 60MS            19.3
    RBBB + LAD      8.21               < 60MS            0.46
    LBBB + RAD      3.93          V6 MORPHOLOGY
    NONE            0.47                    QS           50
V WAVE IN RBBB                    BIPHASIC RBBB R/S<1    50
   TALLER LT PEAK   50            TRIPHASIC RBBB R/S<1   0.13
   Rs OR qR         4.03
   rsR OR rR        0.21
    NONE            1.41                          Sensitivity – 95%
                                                  Specificity – 52%
Wide complex tachycardia
Diagnostic approach/algorithms          aVR CRITERIA




                                           Sensitivity – 96.7%
                                            Specificity – 99%




                                 Heart Rhythm, , Vereckei, A. et al. New
                                 algorithm using only lead aVR for DD of wide
                                 QRS complex tachycardia., 2008
Wide complex tachycardia
Diagnostic approach/algorithms


                                 Sen.10%    The sensitivity [95.7 vs.
                                 Spe.100%
                                            88.2, P < 0.001] and NPV
                                            [83.5% vs. 65.3% for VT
                                 Sen.48%    diagnosis of the new
                                 Spe.98%    algorithm were superior to
                                            those of the Brugada criteria
                                 Sen.89%
                                 Spe.89%

                                            Application of a new algorithm in the DD
                                 Sen.95%    of wide QRS complex tachycardia AndraÂŽs
                                 Spe.80%    Vereckei et al . EHJ 2007.
Wide complex tachycardia
Diagnostic approach/algorithms


ALGORITHM      ORIGINAL STUDY     LAU & NG(2001)   ISENHOUR(2000)
               SEN.       SPEF.   SEN.      SPE.   SEN       SPE.
BRUGADA        98.7       96.5    92        44     79-91    43-70

GRIFFITH       95         64      92        44

BAYESIAN       95          52     97        56
Wide complex tachycardia
Diagnostic approach/algorithms


 Comparison of five electrocardiographic methods for differentiation
  of wide QRS-complex tachycardias
 Brugada, Bayesian, Griffith, and aVR algorithms, and the lead II R-
  wave-peak-time (RWPT) criterion
 All five algorithms/criteria had equal moderate diagnostic accuracy.
 The newer methods were not more accurate than the classic Brugada
  algorithm


               Comparison of five electrocardiographic methods for differentiation
               of wide QRS-complex tachycardias.Jastrzebski.M Europace 2010 feb
               14
Wide complex tachycardia


Best algorithmic approach for diagnosing WCT
1. BRUGADA
2. aVR criteria
3. Vereckei combined criteria(old & aVR criteria)
Wide complex
tachycardia

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WIDE QRS TACHYCARDIA

  • 1. Wide QRS Tachycardia MSN PAVAN KUMAR
  • 2. Wide complex tachycardia  Definitions  Causes  Features for differentiation  Diagnostic approach/algorithms
  • 3. Wide complex tachycardia Definition :  A rhythm with QRS duration ≄ 120 ms and heart rate > 100/min.  Sustained vs non sustained
  • 4. Wide complex tachycardia Causes : Regular : 1. Ventricular tachycardia(80% of WCT) 2. Any SVT with aberrancy (2nd MC WCT) 3. Any SVT with BBB 4. Any SVT with delayed conduction d/t drugs and electrolytes a. Class IA,IC ; hyperkalemia. 5. Antidromic AVRT(1-5%) 6. Pacemaker mediated rhythm Irregular : 1. AF with conduction on preexcitation pathway. 2. Any irregular SVT with aberrancy , BBB . 3. VT in the 1st 30 sec , pts on anti arrythmitic drugs – cycle length varibility.
  • 5. Wide complex tachycardia Features for differentiation :  Pacemaker rhythm(<1% of WCT) 1. History and physical examination 2. ECG: a. Stimulus artefact b. LBBB with left superior axis(if RV apical pacing) , various combinations ( biventricular pacing)
  • 6. Wide complex tachycardia Features for differentiation : VT vs Preexcited tachycardia ‱VT – Predominantly negative QRS complexes in V4-V6 – Presence of a QR complex in one or more leads V2-V6 – More QRS complex than P ‱75% sensitivity & 100% specificity for VT (Stierer et al)
  • 7. Wide complex tachycardia  Features for differentiation :  History and physical examination: 1. H/o heart disease – previous MI , angina , CHF – have a PPA of 95% for diagnosing VT 2. Pts with VT are older than SVT (> 35 yrs) 3. SVT-A often have h/o previous episode(>3years) 4. Pts with SVT-A are hemodynamically stable. 5. Examination for AV dissociation a. Cannon A waves in JVP b. Variable S1 intensity c. Variation in SBP unrelated to respiration. 6. Termination of WCT with physical manoeuvres and medications
  • 8. Wide complex tachycardia  Features for differentiation by ECG : 1. QRS duration 2. QRS axis 3. Concordant pattern 4. Precordial RS duration. 5. Morphological criteria - RBBB , LBBB , ambiguous chest lead pattern 6. Q wave presence 7. AV dissociation 8. Baseline QRS prolongation – QRS duration , QRS configuration. 9. aVR changes. 10.Lead II R-wave-peak-time (RWPT) criterion .
  • 9. Wide complex tachycardia 1. QRS duration :  > 160 ms with LBBB , >140 ms with RBBB - VT  Wellens et al . Showed that 69% of VT had QRS duration of >140ms and none of SVT-A showed QRS duration of >140ms.  Exceptions: a. Anti arrythmitic drugs non specifically prolong QRS duration. b. Pts with structurally normal heart may have VT with QRS duration of 120-140ms.(<140ms in12% , < 120 ms in 4%) c. QRS duration also depend site of origin of VT , septal VT QRS duration has sensitivity of 70%
  • 11. Wide complex tachycardia 2. QRS axis :  Frontal plane axis of -90 to +180 --- VT  Shift in QRS axis of more than 40 from baseline --- VT(less specific)  RBBB with LAD, LBBB with RAD --- VT.  LAFB (-30 to -90) , LPFB (+110 to150) and RBBB (normal axis).
  • 12. Wide complex tachycardia 3.Concordant QRS in chest leads:  Concordant QRS in chest leads is diagnostic of VT uncommon in SVT-A.  Exceptions:  Positive concordance (ventricular activation begins left posteriorly) seen in VT originating in Lt post wall or SVT using a left posterior accessory pathway for AV conduction.  If no additional criteria for WPW are absent don’t consider it because of low incidence(<6%) Specificity of 90%, Sensitivity of 20%
  • 14. Wide complex tachycardia 3.Concordant QRS in limb leads :  The presence of predominantly negative QRS complexes in leads 1,2,3 is suggestive of VT  This is another way to describe right superior axis  Similar to RS axis it is considered as highly specific for VT
  • 15. Wide complex tachycardia 4.Pericardial RS duration criteria :  If concordant QRS complexes are absent i.e with RS complex onset of R wave to nadir of S wave > 100 ms. Sensitivity – 66% Specificity - 98%
  • 16. Wide complex tachycardia 5.RBBB – V1 :  rSr , rSR , rR , rsr patterns consistent with SVT-A  R , R>30ms with any negative QRS , qR --- VT  This is because right ventricle doesn’t participate in initial QRS Sensitivity – 30-80% Specificity - 84-95%
  • 17. Wide complex tachycardia 5.RBBB – V6 :  qRs , Rs , RS with R/S >1 --- SVT –A  R , QR , QS , RS with R/S < 1 --- VT Sensitivity – 30-60% Specificity - 80-100%
  • 18. Wide complex tachycardia 5. LBBB – V1,V6: Sensitivity – 100% Sensitivity – 17% Specificity - 89% Specificity - 100%
  • 19. Wide complex tachycardia 5.Ambiguous chest lead pattern:  W and M pattern in V1 have been classified as LBBB & RBBB  Because they are ambiguous in this way, they are unlikely to represent typical aberration and are highly specific for VT.  Sensitivity of 60-80% , specificity of 90-95%.
  • 20. Wide complex tachycardia 6. Q wave presence :  Q during WCT --- suggest old MI --- VT most likely.  In general pts with post MI VT maintain Q wave during WCT that are present during baseline in the same lead.  Exceptions : 1. Pts with DCMP will have Q wave during VT that are not present during baseline. 2. PSEUDO Q wave with retrograde p wave deforming QRS can be seen in SVT-A 3. Preexcited tachycardia with posterior AV connection can have Q wave in inferior leads
  • 21. Wide complex tachycardia 7. AV dissociation :  The most specific ECG finding for VT .  Clues for AV dissociation: 1. Clinically by cannon A waves , variable intensity of S1 , Variation in SBP unrelated to respiration. 2. AV dissociation 3. AV ratio of less than 1 4. 2:1 VA block(d/t retrograde conduction) 5. Variation in QRS amplitude during WCT 6. Fusion & capture beats 7. Recording separate atrial electro gram (oesophageal/transvenous) 8. Echo (evaluating RA contraction in relation to ventricular)
  • 22. Wide complex tachycardia 7. AV dissociation : V rate = 215/mt A rate = 125/mt A/V =0.58
  • 23. Wide complex tachycardia 7. AV dissociation : VT with retrograde 2:1 VA conduction (seen in 15-20% of VT)
  • 24. Wide complex tachycardia 7. AV dissociation :  Variation in amplitude of QRS during WCT 1. Scalar summation of P wave with QRS 2. Variable ventricular filling in the presence of AVD  Presence of multiple WCT configuration has a sensitivity of 55% for diagnosing VT
  • 25. Wide complex tachycardia 7. AV dissociation :  The QRS complex is prolonged, and the R-R interval is regular except for occasional capture beats (C) that have a normal contour and are slightly premature. Complexes intermediate in contour represent fusion beats (F).  Thus, even though atrial activity is not clearly apparent, atrioventricular dissociation is present during ventricular tachycardia and produces intermittent capture and fusion beats
  • 26. Wide complex tachycardia 7. AV dissociation :
  • 27. Wide complex tachycardia 7. AV dissociation :  Caveats while using AVD: 1. Low sensitivity (20-50%) is d/t fast heart rates , inadequate duration of recording , observer inexperience. 2. 30% of pts , especially VT with low V rate , have 1:1 VA conduction – differentiate by vagal maneuvers , adnosine. 3. AF and VT co exist AVD cannot be diagnosed . Sensitivity – 20-50% Specificity – 98%
  • 28. Wide complex tachycardia 8. Base line QRS prolongation: a. Pt with baseline QRS rhythm and WCT QRS different – VT 1. QRS during VT is narrower than baseline rhythm 2. Contra lateral BBB in baseline rhythm and during WCT 3. AV dissociation 4. Rarely other findings may be useful like precordial concordance , north-west axis , monophasic R wave in V1 Pts with BBRT Impulse originates in RBB Travels through LBB Have typical features of LBBB
  • 29. Wide complex tachycardia 9. aVR changes : 1. Presence of initial ‘r’ wave in aVR 2. Presence of initial ‘r’ or ‘q’ wave of > 40ms duration 3. Presence of notch in descending limb of negative onset and predominantly negative QRS 4. Vi/Vt ≀ 1 All the above features are indicative of VT Sensitivity – 96.7% Specificity – 99%
  • 30. Wide complex tachycardia 9. aVR changes : Initial ‘r’ wave in aVR During SVT with aberrancy , initial septal activation and main ventricular activation are directed away from lead aVR  negative QRS complex Exceptions : 1. Inferior MI- initial r wave (rS complex) during NSR or SVT 2. VT originating from base of heart may not have initial r wave
  • 32. Wide complex tachycardia 9. aVR changes : Vi/Vt ≀ 1 Vi = voltage in the initial 40ms of QRS Vt = voltage in the terminal 40ms of QRS In SVT-A only one portion is bundle branch is blocked --- so the initial portion of QRS is rapid compared to terminal portion. In VT slow muscle to muscle spread of impulse causes slower voltage changes through out QRS complex Can be applied to any lead The vi/vt was > 1 (signifying supraventricular origin) in 88% tracings with LBBB pattern, in 98% with RBBB pattern, and 90% with nonspecific IVCD.
  • 33. Wide complex tachycardia 9. aVR changes : Vi/Vt ≀ 1
  • 34. Wide complex tachycardia 10. Lead II R-wave-peak-time (RWPT) criterion : Pavas criteria RWPT > or =50 ms at DII is a simple and highly sensitive criterion that discriminates VT from SVT in patients with wide QRS complex tachycardia. Sensitivity and specificity of 97% Heart Rhythm. 2010 Jul;7(7):922-6. Epub 2010 Mar 4.
  • 35. Wide complex tachycardia  Diagnostic approach/algorithms 1. Wellens(1978) , Akhtar(1988) , 2. Brugada(1991) 3. Griffith(1994) 4. Bayesian(1995) 5. aVR algorithms(2007) 6. lead II R-wave-peak-time (RWPT) criterion(2010) 7. Combined .
  • 36. Wide complex tachycardia Diagnostic approach/algorithms WELLENS CRITERIA AKHTAR CRITERIA
  • 37. Wide complex tachycardia Diagnostic approach/algorithms BRUGADA CRITERIA Sensitivity – 98.7% Specificity – 96.5% Brugada P, Brugada Jet al.A new approach to the DD of a regular tachycardia with a wide QRS complex. Circulation. 1991;83:1649-16595
  • 38. Wide complex tachycardia Diagnostic approach/algorithms GRIFFITH CRITERIA WCT NO YES VT YES INDEPENDENT P WAVES Sensitivity – 95% Griffith MJ,Garratt Ci,et VT as default diagnosis in Specificity – 64% broad complex tachycardia. Lancet 1994 feb
  • 39. Wide complex tachycardia Diagnostic approach/algorithms BAYESIAN CRITERIA CRITERIA LR V WAVE IN LBBB QRS WIDTH r > 40MS 50 =140MS 0.31 NOTCH IN ‘S’ 50 140-160MS 0.48 R-S > 60MS 50 > 160MS 22.86 NONE 0.13 QRS AXIS INTRINSICOID IN V6 NW AXIS 7.86 = 60MS 19.3 RBBB + LAD 8.21 < 60MS 0.46 LBBB + RAD 3.93 V6 MORPHOLOGY NONE 0.47 QS 50 V WAVE IN RBBB BIPHASIC RBBB R/S<1 50 TALLER LT PEAK 50 TRIPHASIC RBBB R/S<1 0.13 Rs OR qR 4.03 rsR OR rR 0.21 NONE 1.41 Sensitivity – 95% Specificity – 52%
  • 40. Wide complex tachycardia Diagnostic approach/algorithms aVR CRITERIA Sensitivity – 96.7% Specificity – 99% Heart Rhythm, , Vereckei, A. et al. New algorithm using only lead aVR for DD of wide QRS complex tachycardia., 2008
  • 41. Wide complex tachycardia Diagnostic approach/algorithms Sen.10% The sensitivity [95.7 vs. Spe.100% 88.2, P < 0.001] and NPV [83.5% vs. 65.3% for VT Sen.48% diagnosis of the new Spe.98% algorithm were superior to those of the Brugada criteria Sen.89% Spe.89% Application of a new algorithm in the DD Sen.95% of wide QRS complex tachycardia AndraÂŽs Spe.80% Vereckei et al . EHJ 2007.
  • 42. Wide complex tachycardia Diagnostic approach/algorithms ALGORITHM ORIGINAL STUDY LAU & NG(2001) ISENHOUR(2000) SEN. SPEF. SEN. SPE. SEN SPE. BRUGADA 98.7 96.5 92 44 79-91 43-70 GRIFFITH 95 64 92 44 BAYESIAN 95 52 97 56
  • 43. Wide complex tachycardia Diagnostic approach/algorithms  Comparison of five electrocardiographic methods for differentiation of wide QRS-complex tachycardias  Brugada, Bayesian, Griffith, and aVR algorithms, and the lead II R- wave-peak-time (RWPT) criterion  All five algorithms/criteria had equal moderate diagnostic accuracy.  The newer methods were not more accurate than the classic Brugada algorithm Comparison of five electrocardiographic methods for differentiation of wide QRS-complex tachycardias.Jastrzebski.M Europace 2010 feb 14
  • 44. Wide complex tachycardia Best algorithmic approach for diagnosing WCT 1. BRUGADA 2. aVR criteria 3. Vereckei combined criteria(old & aVR criteria)