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Local anesthetics

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Local Anesthetics www.freelivedoctor.com
Local Anesthetic ,[object Object],www.freelivedoctor.com
History ,[object Object],www.freelivedoctor.com
Chemistry All local anesthetics are weak bases, classified as tertiary amines.  www.freelivedoctor.com
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www.freelivedoctor.com
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Mechanism of Action ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Mechanism of action ,[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
www.freelivedoctor.com
Mechanism of action ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
www.freelivedoctor.com
Factors affecting local anesthetic action ,[object Object],[object Object],www.freelivedoctor.com
Effect of lipophilicity ANESTHETIC POTENCY ,[object Object],[object Object],www.freelivedoctor.com
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FIBER SIZE AND FUNCTION ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
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Susceptibility to block by local anesthetics of types of nerve fibers ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Order of sensory function block ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Recovery in reverse order www.freelivedoctor.com
TOXICITIES OF LOCAL ANESTHETICS ,[object Object],www.freelivedoctor.com
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CNS toxicity cont ,[object Object],[object Object],www.freelivedoctor.com
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[object Object],www.freelivedoctor.com
Types of Local Anesthesia ,[object Object],www.freelivedoctor.com
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Vasoconstrictors ,[object Object],[object Object],www.freelivedoctor.com

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Local anesthetics