http://www.qstore99.com/might-a-mins-spectrum-isotonix-multivitamin.html Might-a-Mins® Spectrum Isotonix® Multivitamin provides children with the vitamins and minerals they need for optimal health. Many children do not obtain the necessary amounts of vitamins and minerals due to high consumption of processed foods, poor nutrient absorption and exposure to environmental toxins. Might-a-Mins Spectrum Isotonix Multivitamin provides children in need of neurological, metabolic or digestive support with a strong micronutrient foundation which promotes healthy development and supports optimal immune functions.

1. Isotonix
Might-a-Mins ®
Spectrum Multivitamin
Crystal H. Shelton
Research Associate
Scientific Affairs

2. Isotonix Might-a-Mins ®
Spectrum
Multivitamin
These statements have not been evaluated by the Food
and Drug Administration. This product is not intended to
diagnose, treat, cure or prevent any disease.

3. Important Ingredients for
Neurological, Metabolic and
Digestive Support
 Folic Acid  Vitamin A
 Vitamin B6 (P5P)  Zinc
 Vitamin B12  Calcium
 Vitamin B3  Magnesium
 Vitamin C

4. Folinic Acid
 Food sources include:  Essential for numerous
 Leafy green vegetables
processes in the body and
(like spinach and turnip supports the normal
greens), fruits (like citrus
fruits and juices), and development of the nervous
dried beans and peas are system
all natural sources of
folate
 Folinic acid (tetrahydrofolic
acid)is the metabolically active
form of folic acid, high
bioavailability

5. Folinic Acid
 Supports the conversion of sulfur-containing compounds to
glutathione, studies show low glutathione due to abnormalities
in methionine pathway
 Antioxidant
 Detoxification
 Because of folic acid’s critical role in neurological function, it
can help to maintain healthy sleep quality, and help facilitate
the normal development of communication and social
interaction skills
 11:1

6. Vitamin B6 (P5P or
Pyridoxine-5-Phosphate)
 Food sources include:  B6 is critical for the normal
 Beans, meat, poultry, fish, development of language,
attention, alertness, etc.
and some fruits and
vegetables
 To be used by the body, B6
must be converted to P5P in
 Master vitamin for numerous
the liver
metabolic pathways in the
body
 Pyridoxal-5-phosphate is the
active form of vitamin B6

7. B6 and Oxalates
 Acts as a cofactor for enzymes that degrade
oxalates
 Molecules present in many plants and fruit, all
seeds and nuts, grains
 When the gut is leaky higher quantities of
oxalates are absorbed from foods

8. Vitamin B6 (P5P or
Pyridoxine-5-Phosphate)
 Vitamin B6 is the most studied nutrient among
children with neuroglogical, metabolic and
digestive issues and is often given in
combination with magnesium.
 B6 naturally requires extra magnesium to be
effective
 11:1

9. Methylcobalamin (Vitamin
B12)
 Food sources include:  Promotes normal
 Naturally found in foods that conversion of sulfur-
come from animals, including containing compounds to
fish, meat, poultry, eggs, milk, glutathione (antioxidant
and milk products and detox)
 A water-soluble vitamin  Vitamin B12 deficiency is
that supports normal commonly found in
nerve cell activity, DNA children with neurological,
replication, and metabolic and digestive
production of the mood- needs
affecting substance
SAMe (S-adenosyl-L-
methionine)

10. Methylcobalamin (Vitamin
B12)
 Methylated form of B12,  The most highly
evidence indicates reduced form of vitamin
methylcobalamin is utilized B12 possible
more efficiently than
cobalamin
 Why Methylcobalamin?
 Already metabolically
 Methylcobalamin doesn't active
have to engage the body's
resources to convert it into
 Maximally reduced
coenzyme form  Less of a strain on our
bodies' antioxidant capacity
 Methylcobalmin is closely  4:1
allied with the folic acid
biochemical pathway and
promotes normal
detoxification

11. Vitamin B3
(Niacin/Niacinamide)
 Food sources include:  A water-soluble vitamin
 Beets, brewer's yeast, beef necessary for numerous
liver, beef kidney, pork, metabolic pathways in the
turkey, chicken, veal, fish, body
tuna, peanuts
 Involved in pathways that
sustain and renew the
body’s tissues
 10:1

12. Vitamin C
 Water-soluble vitamin, also  Cofactor for dopamine
known as ascorbic acid production, helps maintain
brain health
 Food sources include:  Vitamin C also promotes
 Oranges, green peppers, glutathione levels, another
strawberries, other fruit, important antioxidant in the
tomatoes, broccoli
body
 Promotes normal tissue  19:1
repair, bone healing, immune
function among other things
 Proven antioxidant

13. Vitamin C
 A large study by James et al. confirmed low glutathione levels
in children and associations with abnormalities in their
methionine pathway, i.e. increased oxidative stress
 153 children studied for transmethylation and transulfuration
issue and 565 children evaluated for common polymorphic
variants known to modulate these pathways
 James et al. Metabolic endophenotype and related genotypes are
associated with oxidative stress in children with autism. American
Journal of Medical Genetics. 141B(8):947-56, 2006.
 Vitamin C supported red blood cell glutathione levels in
college students
 Johnston et al. Vitamin C elevates red blood cell glutathione in healthy
adults. American Journal of Clinical Nutrition. 58(1):103-5, 1993.

14. Vitamin A (Beta-Carotene)
 Essential vitamin –  Powerful antioxidant
 Beta-Carotene → retinal
form of vitamin A → retinol  Vitamin A deficiency is
 Food sources include: commonly found in children
 Yellow and orange fruits
with neurological, metabolic
(carrots, papaya. mangos), and digestive needs
green leafy veggies (spinach)
 19:1
 Supports normal cell growth
and differentiation,
especially in tissues of the
gut and brain, helps
maintain vision and immune
functions

15. Zinc
 Food sources include:  Copper imbalance in children
 Oysters, red meat, beans, is also associated with delayed
nuts, certain seafood, whole development, anti-social and
grains hyperactive behavior, learning
difficulties
 An essential mineral
 Because zinc helps facilitate
 When zinc levels are down, the excretion of excess
copper levels are often copper, it is important to make
increased sure a multivitamin has an
adequate amount of zinc
 Children who need
neurological or digestive
 Avoid copper-containing
support often have an supplements
abnormal zinc to copper ratio
 22:1

16. Calcium
 Food sources include:  Calcium supplementation
 Dairy, milk, yogurt, cheese, may help to promote
green leafy vegetables normal oxalate absorption
 Bind to dietary calcium and
is removed through the
 This mineral promotes digestive tract and not
normal: absorbed
 bone health
nerve transmission
It’s especially important to


 muscle contraction
 vasodilation supplement calcium in
 enzyme reactions those on a casein-free
 respiration diet
 among many others
 14:1

17. Magnesium
 Food sources include:  Combination of B6 and
 Green vegetables (spinach), magnesium
legumes (beans and peas),
nuts and seeds
 4.6:1 and 11:1
(combination)
 Essential mineral
 Supports the proper
functioning of many enzymes,
including those responsible
for the production of
neurotransmitters in the brain

18. Recent Multivitamin
Research
 A small pilot study found that a strong, balanced multi-
vitamin/mineral supplement resulted in improvements in
sleep and promoted normal gut function in children, and
possibly in other areas
 20 children ages 3-8 years old
 Given a multivitamin/multimineral supplement for 3 months
 Based on parental assessment, there were statistically significant
improvements in sleep and supported GI comfort
 Also determined a functional need for more vitamin B6 and vitamin
C
 Adams J et al. Pilot study of a moderate dose multivitamin/mineral
supplement for children with autistic spectrum disorder. Journal of
Alternative and Complementary Medicine. 10(6):1033-1039, 2004.

19. Conclusion
• The need for increased support in the areas of
neurology, metabolism and digestion is more prevalent
in our society than ever before, but there are proven
nutritional approaches that may help:
 Recap of important ingredients:
 Folinic acid
 P5P (Vitamin B6)
 Methylcobalamin
 Vitamin C
 Zinc
 Calcium
 Magnesium

20. Isotonix Might-a-Mins ®
Spectrum
Multivitamin
 $54.95
 FreeShipping
 www.Qstore99.com

22. Isotonix Might-a-Mins ®
Spectrum
Multivitamin
 Helps to promote normal levels of vitamins and
minerals in individuals who need neurological,
digestive or metabolic support
 Helps maintain the normal production of
neurotransmitters
 Promotes/supports a healthy nervous system
 Helps maintain brain health
 Promotes a healthy development of sensory and
communication skills.

23. Isotonix Might-a-Mins ®
Spectrum
Multivitamin
 Provides strong antioxidant defense
 Combats free radicals
 Promotes normal tissue and cell growth
 Provides nutrients essential for numerous processes
in the body
 Supports optimal immune functions
 Supports skeletal health and growth
 Supports healthy teeth and gums
 Supports growth and strength of teeth and bones
 Supports cognitive health and development
 Supports healthy vision and eyes
 Supports a healthy heart

24. References
 Kidd P. Autism, an extreme challenge to integrative medicine. Part II: medical
management. Alternative Medicine Review. 7(6):472-499, 2002.
 Adams J. Summary of Biomedical Treatments for Autism. Autism Research
Institute Publication. 40 (April), 2007.
 Adams J et al. Pilot study of a moderate dose multivitamin/mineral supplement for
children with autistic spectrum disorder. Journal of Alternative and Complementary
Medicine. 10(6):1033-1039, 2004.
 Megson M. Is autism a G-alpha protein defect reversible with natural vitamin A?
Medical Hypotheses. 54(6):979-983, 2000.
 Lelord G et al. Effects of pyridoxine and magnesium on autistic symptoms: initial
observations. Journal of Autism Developmental Disorders. 11(2):219-229, 1981.
 Martineau J et al. Effects of vitamin B6 on averaged evoked potential in infantile
autism. Biological Psychiatry. 16(7):627-641, 1981.
 Martineau J et al. Vitamin B6, magnesium, and combined B6-Mg: therapeutic
effects in childhood autism. Biological Psychiatry. 20(5):467-478, 1985.
 Lonsdale D et al. Treatment of autism spectrum children with thiamine
tetrahydrofurfuryl disulfide: A pilot study. Neuroendocrinology Letters. 23(4):303-
308, 2002.
 Rimland B et al. The effect of high doses of vitamin B6 on autistic children: a
double-blind cross-over study. American Journal of Psychiatry. 135(4):472, 1978.
 Rimland B. Vitamin B6 (and magnesium) in the treatment of autism. Autism
Research Review International. 1(4), 1987.

25. References
 Dolske M. et al. A preliminary trial of ascorbic acid as supplemental therapy for autism.
Progress in Neuropsycho-pharmacology and Biological Psychiatry. 17(2):765-774, 1993.
 Rimland B. Vitamin C in the Prevention and Treatment of Autism. Autism Research Review
International. 12:3, 1998.
 Martineau J et al. Brief report: an open middle-term study of combined vitamin B6-
magnesium in a subgroup of autistic children selected on their sensitivity to this treatment.
Journal of Autism and Developmental Disorders. 18:435-447, 1988.
 Martineau J et al. Electrophysiological effects of fenfluramine or combined vitamin B6 and
magnesium on children with autistic behavior. Developmental Medicine and Child
Neurology. 31:728-736, 1989.
 Audhya T. (2002, October). Laboratory indices of vitamin and mineral deficiency in autism.
Paper presented at the Defeat Autism Now! Conference, San Diego, California.
 Angley M et al. Children and autism--Part 2--management with complementary medicines
and dietary interventions. Australian Family Physician. 36(10):827-30, 2007.
 Levy S et al. Novel treatments for autistic spectrum disorders. Mental Retardation and
Developmental Disabilities Research Reviews. 11(2):131-42, 2005. Review.
 Rimland B. Controversies in the treatment of autistic children: vitamin and drug therapy.
Journal of Child Neurology. 3 Suppl:S68-72, 1988.
 Pfeiffer S et al. Efficacy of vitamin B6 and magnesium in the treatment of autism: a
methodology review and summary of outcomes. Journal of Autism and Developmental
Disorders. 25(5):481-93, 1995.
 Kleijnen J and Knipschild P. Niacin and vitamin B6 in mental functioning: a review of
controlled trials in humans. Biological Psychiatry. 29(9):931-41, 1991.

26. References
 Kotsanis C et al. Autism – A multidisciplinary approach to treatment. Study
Profile, DFW Ear, Nose & Throat Associates. Grapevine TX. No date given.
 Levy A and Hyman S. Use of complementary and alternative treatments for
children with autistic spectrum disorders is increasing. Pediatric Annals. 32:685-
91, 2003.
 Werbach M. Nutritional treatments for autism - nutritional influences on illness.
Townsend Letter for Doctors and Patients. October 2003.
 Autism Research Institute. http://www.autism.com/ari/. Accessed May and June
2008.
 Osendarp S et al. Effect of a 12-mo micronutrient intervention on learning and
memory in well-nourished and marginally nourished school-aged children: 2
parallel, randomized, placebo-controlled studies in Australia and Indonesia.
American Journal of Clinical Nutrition. 86(4):1082-93, 2007.
 Mousain-Bosc M et al. Improvement of neurobehavioral disorders in children
supplemented with magnesium-vitamin B6. Magnesium Research. 19(1):53-62,
2006.
 Moretti P et al. Cerebral folate deficiency with developmental delay, autism, and
response to folinic acid. Neurology. 64(6):1088-90, 2005.
 Marlow M et al. Decreased magnesium in the hair of autistic children. Journal of
Orthomolecular Psychiatry. 13(2):117-122, 1984.