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Dr.Punita Adajania
WHAT IS BIOENERGETICS?
 Different

sports require specific sources of

energy.


The body stores energy in a variety of ways—
in ATP, PCr, muscle glycogen,etc



In order for this energy to be used,it must
undergo certain biochemical reactions in the
muscle.
 These

biochemical reactions serve as a basis
for classifying human energy expenditure by
three energy systems:

the ATP-PCr system(phosphagen system)
 the lactic acid system
 the oxygen system

ENERGY SYSTEMS




Also known as the phosphagen system.
ATP is the immediate source of energy for
almost all body processes.

 The

ATP-PCr system is critical to energy
production.


The value of the ATP-PCr system is its ability
to provide energy rapidly.

 In

sport events such as competitive weight
lifting or sprinting 100 meters.

 Anaerobic

power is a term often associated
with the ATP-PCr energy system.


Cannot be used directly as a source of
energy for muscular contraction.

 but

it can help replace ATP rapidly when
necessary.

 Muscle

glycogen must be broken down to
glucose, which undergoes a series of
reactions to eventually form ATP, a process
called glycolysis.
 Aerobic

glycolysis.

 Anaerobic

 Anaerobic

glycolysis.

glycolysis is the scientific term
for the lactic acid energy system.
 It

is used in sport events in which energy
production is near maximal for 30–120
seconds, such as a 200- or 800-meter run.

 The

lactic acid system has the advantage of
producing ATP rapidly.
 the

lactic acid produced as a by- product
may be involved in the onset of fatigue.
 Also

known as the aerobic system.

 Aerobic

exercises are designed to stress the
oxygen system and provide benefits for the
heart and lungs.

 The

oxygen system cannot be used directly
as a source of energy for muscle
contraction, but it does produce ATP in large
quantities from other energy sources in the
body.
 Muscle

glycogen, liver glycogen, blood
glucose, muscle triglycerides, blood FFA and
triglycerides, adipose cell triglycerides, and
body protein all may be ultimate sources of
energy for ATP production and subsequent
muscle contraction.

 Through

a complex series of reactions
metabolic by-products of
carbohydrate, fat, or protein combine with
oxygen to produce energy, carbon
dioxide, and water.
 The

whole series of events of oxidative
energy production primarily involves aerobic
processing of carbohydrates and fats through
the Krebs cycle and the electron transfer
system.
 The
 The

rate of ATP production is lower.

major advantage of the oxygen system
over the other two energy systems is the
production of large amounts of energy in the
form of ATP.
 This

process may be adequate to handle mild
and moderate levels of exercise but may not
be able to meet the demand of very
strenuous exercise.

 The

oxygen system is used primarily in sports
emphasizing endurance, such as distance
runs ranging from 5 kilometers (3.1 miles) to
the 26.2-mile marathon and beyond.
 Aerobic

energy processes take place in the
mitochondria of cells.

 During

steady-state exercise, the pyruvic
acid produced is converted to acetyl-CoA in
the mitochondria and then undergoes aerobic
oxidation.

 Fats

are another major source of energy
during prolonged exercise and can only be
used to produce energy using aerobic
processes.
 Each

of the three energy systems can
generate power to different capacities and
varies within individuals.

 Best

estimates suggest that the ATP-PCR
system can generate energy at a rate of
roughly 36 kcal per minute. Glycolysis can
generate energy only half as quickly at about
16 kcal per minute. The oxidative system
has the lowest rate of power output at about
10 kcal per minute.
 The

three energy systems do not work
independently of one another.

 From

very short, very intense exercise, to
very light, prolonged activity, all three
energy systems make a contribution
however, one or two will usually
predominate.
 Two

factors of any activity carried out affect
energy systems more than any other variable
they are the intensity and duration of
exercise.
A NEW MODEL FOR ENERGY SYSTEMS?


In the year 2000, Noakes and colleagues questioned
the classical model of energy systems.



Their argument centered around these key issues:
The heart and not skeletal muscle would be
affected first by anaerobic metabolism.
No study has definitively found a presence of
anaerobic metabolism and hypoxia (lack of oxygen)
in skeletal muscle during maximal exercise.
The traditional model is unable to explain why
fatigue ensues during prolonged exercise, at
altitude and in hot conditions.
Cardiorespiratory and metabolic measures such as
VO2max and lactate threshold are only modest
predictors of performance.







 In

an attempt to produce a more holistic
explanation, Noakes developed a model that
consisted of five sub-models:
 The classical 'cardiovascular / anaerobic'
model as it stands now.
 The energy supply / energy depletion
model.
 The muscle recruitment (central fatigue) /
muscle power model.
 The biomechanical model.

The psychological / motivational model.
SOURCES OF ENERGY IN
DIFFERENT ACTIVITIES


Any energy requiring processes invariably uses
ATP as the prime source of energy.



At the start of an activity the initial source of
energy is from ATP stores at the muscle
crossbridges.



The amount of ATP in muscle is rather small.



This amount of ATP in muscle has been estimated
to be sufficient to fuel around 3–5 seconds of
maximal effort if ATP was the sole energy
source.
 The

other immediate source of energy for
high intensity exercise is that of creatine
phosphate or phosphocreatine (PCr).

 Creatine

phosphate (PCr) rapidly replaces
the ATP and becomes the next major source
of energy.

 This

amount of PCr is sufficient to fuel
maximal exercise solely for approximately 6–
8 s.
 An

essential store of carbohydrate fuel for
both high- intensity exercise and prolonged
activity.

 Normal

muscle glycogen stores have a
concentration of 350 mM kg–1 dry muscle.

 Can

be increased significantly by a high
carbohydrate diet and reduced significantly
by repeated bouts of sprinting or a single
prolonged bout of exercise or when on a low
carbohydrate diet for around 2–4 days.
 When

muscle glycogen breaks down to
produce energy, under the influence of the
enzyme glycogen phosphorylase.

 The

process of breaking off glucose
molecules from glycogen is known as
glycogenolysis.

 Glycolysis

is a series of processes which takes
place in the cytoplasm of cells resulting in
the formation of two pyruvic acid molecules
and ATP.
 If

the activity is intense, the pyruvic acid
leads to the formation of lactic
acid, although during steady-state exercise
the majority of the pyruvic acid formed is
broken down to produce carbon dioxide and
water.
 Glucose

delivered to the muscle by blood
may also act as a useful energy source during
exercise.
ROLE OF NUTRIENTS IN
BIOENERGETICS
 Proper

nutrition forms the foundation for
physical performance.

 NUTRITION:-

MACRONUTRIENTS &
MICRONUTREINTS.
Six broad categories of nutrients:
 carbohydrates
 fats
 proteins
 vitamins
 minerals
 water
 Provide

a rapid and readily available source
of energy.

 Found

in three forms:
monosaccharides, disaccharides, and
polysaccharides.

 Glucose

is the most important simple sugar
and is the only form of carbohydrate that can
be directly metabolized to obtain energy.
 Glycogen

is not found in plants and is the
polysaccharide form in which animals store
carbohydrate.

 During

exercise, glucose molecules can be
removed from glycogen in the liver by
glycogenolysis, and released into the
bloodstream to provide glucose as a
metabolic substrate to other cells of the
body.
 Glucose

and glycogen are the carbohydrates
important for metabolism at rest and during
exercise.
 During exercise, muscle cells can obtain
glucose by absorbing it from the bloodstream
or by glycogenolysis from intramuscular
glycogen stores.
 glycogenolysis in the liver can maintain blood
glucose levels during exercise and at times of
rest between meals.
 At

rest, carbohydrate is taken up by the
muscles and liver and converted
into glycogen.

 Glycogen

can be used to form ATP and in the
liver it can be converted into glucose and
transported to the muscles via the blood. A
heavy training session can deplete
carbohydrate stores in the muscles and liver.

 Carbohydrate

can release energy much more
quickly than fat.
 Fat

is stored predominantly as adipose tissue
throughout the body and is a substantial
energy reservoir.

 It

is less accessible for cellular metabolism as
it must first be reduced from its complex
form, triglyceride, to the simpler
components of glycerol and free fatty acids.

 So

although fat acts as a vast stockpile of
fuel, energy release is too slow for very
intense activity.
 Protein

is used as a source of
energy, particularly during prolonged
activity.



however it must first be broken down into
amino acids before then being converted into
glucose. As with, fat, protein cannot supply
energy at the same rate as carbohydrate.
 Consuming

mineral supplements above
recommended levels on an acute or chronic
basis does not benefit exercise performance
or enhance trainin responsiveness.

 Excessive

water and electrolyte loss impairs
heat tolerance and exercise performance and
can trigger heat cramps, heat exhaustion, or heat stroke.
 During

practice or competition, an athlete
sweats up to 5 kg of water.

 This

corresponds to about 8.0 g of salt
depletion because each kilogram of sweat
contains about 1.5 g of salt (of which 40%
represents sodium).

 Immediate

replacement of water lost
through sweating should become the
overriding consideration.
ENERGY EXPENDITURE AT
REST AND ACTIVITY
 Three

factors determine the total daily
energy expenditure (TDEE):

1. Resting metabolic rate
2. Thermogenic influence of consumed food
3. Energy expended during physical activity
and recovery.
A

minimum energy requirement that sustains
the body’s functions in the waking state.
 Measuring

oxygen uptake under the following
three standardized conditions quantifies this
requirement called the basal metabolic
rate(BMR):

1. No food consumed for a minimum of 12
hours before measurement
2. No undue muscular exertion for at least 12
hours before measurement
3. Measured after the person has been lying
quietly for 30 to 60 minutes in a dimly
lit, temperature- controlled room.
 It

is measured under less strict conditions
(e.g., 3 to 4 hours after a light meal without
physical activity.)
 Estimates

of energy expenditure during rest
and during exercise are often based on
measurement of whole body oxygen
consumption (VO2) and its caloric
equivalent.

 Under

resting conditions, an average person
consumes about 0.3 L of O2/min. or 18L of
O2/hr. or 432L of O2/day.
 One

standardized measure of energy
expenditure at rest is BMR.

Factors affecting BMR are:
 Gender
 Body surface area
 Age
 Body temperature
 Psychological stress
 Hormones-thyroxine, epinephrine
 BMR

of a normal individual varies from 1200
to 2400 Kcal/day.

 Energy

expenditure for athletes engaged in
intense training can exceed 10000Kcal/day.
MEASUREMENT OF ENERGY
EXPENDITURE
 Energy

expenditure can be measured using
one of the three approaches:

indirect calorimetry
 direct calorimetry
 non-calorimetric techniques:
Isotope dilution, doubly labelled water

 Essentials

of Exercise Physiology, fourth
edition, Victor L. Katch,William D.
McArdle, Frank I. Katch.



Exercise Physiology Integrating Theory and
Application, William J. Kraemer, Steven J.
Fleck, Michael R. Deschenes.
Bioenergetics in sports and performance

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Bioenergetics in sports and performance

  • 3.  Different sports require specific sources of energy.  The body stores energy in a variety of ways— in ATP, PCr, muscle glycogen,etc  In order for this energy to be used,it must undergo certain biochemical reactions in the muscle.
  • 4.  These biochemical reactions serve as a basis for classifying human energy expenditure by three energy systems: the ATP-PCr system(phosphagen system)  the lactic acid system  the oxygen system 
  • 6.   Also known as the phosphagen system. ATP is the immediate source of energy for almost all body processes.  The ATP-PCr system is critical to energy production.
  • 7.
  • 8.  The value of the ATP-PCr system is its ability to provide energy rapidly.  In sport events such as competitive weight lifting or sprinting 100 meters.  Anaerobic power is a term often associated with the ATP-PCr energy system.
  • 9.  Cannot be used directly as a source of energy for muscular contraction.  but it can help replace ATP rapidly when necessary.  Muscle glycogen must be broken down to glucose, which undergoes a series of reactions to eventually form ATP, a process called glycolysis.
  • 10.  Aerobic glycolysis.  Anaerobic  Anaerobic glycolysis. glycolysis is the scientific term for the lactic acid energy system.
  • 11.
  • 12.  It is used in sport events in which energy production is near maximal for 30–120 seconds, such as a 200- or 800-meter run.  The lactic acid system has the advantage of producing ATP rapidly.
  • 13.  the lactic acid produced as a by- product may be involved in the onset of fatigue.
  • 14.  Also known as the aerobic system.  Aerobic exercises are designed to stress the oxygen system and provide benefits for the heart and lungs.  The oxygen system cannot be used directly as a source of energy for muscle contraction, but it does produce ATP in large quantities from other energy sources in the body.
  • 15.
  • 16.  Muscle glycogen, liver glycogen, blood glucose, muscle triglycerides, blood FFA and triglycerides, adipose cell triglycerides, and body protein all may be ultimate sources of energy for ATP production and subsequent muscle contraction.  Through a complex series of reactions metabolic by-products of carbohydrate, fat, or protein combine with oxygen to produce energy, carbon dioxide, and water.
  • 17.  The whole series of events of oxidative energy production primarily involves aerobic processing of carbohydrates and fats through the Krebs cycle and the electron transfer system.
  • 18.
  • 19.  The  The rate of ATP production is lower. major advantage of the oxygen system over the other two energy systems is the production of large amounts of energy in the form of ATP.
  • 20.  This process may be adequate to handle mild and moderate levels of exercise but may not be able to meet the demand of very strenuous exercise.  The oxygen system is used primarily in sports emphasizing endurance, such as distance runs ranging from 5 kilometers (3.1 miles) to the 26.2-mile marathon and beyond.
  • 21.  Aerobic energy processes take place in the mitochondria of cells.  During steady-state exercise, the pyruvic acid produced is converted to acetyl-CoA in the mitochondria and then undergoes aerobic oxidation.  Fats are another major source of energy during prolonged exercise and can only be used to produce energy using aerobic processes.
  • 22.  Each of the three energy systems can generate power to different capacities and varies within individuals.  Best estimates suggest that the ATP-PCR system can generate energy at a rate of roughly 36 kcal per minute. Glycolysis can generate energy only half as quickly at about 16 kcal per minute. The oxidative system has the lowest rate of power output at about 10 kcal per minute.
  • 23.  The three energy systems do not work independently of one another.  From very short, very intense exercise, to very light, prolonged activity, all three energy systems make a contribution however, one or two will usually predominate.
  • 24.  Two factors of any activity carried out affect energy systems more than any other variable they are the intensity and duration of exercise.
  • 25.
  • 26. A NEW MODEL FOR ENERGY SYSTEMS?
  • 27.  In the year 2000, Noakes and colleagues questioned the classical model of energy systems.  Their argument centered around these key issues: The heart and not skeletal muscle would be affected first by anaerobic metabolism. No study has definitively found a presence of anaerobic metabolism and hypoxia (lack of oxygen) in skeletal muscle during maximal exercise. The traditional model is unable to explain why fatigue ensues during prolonged exercise, at altitude and in hot conditions. Cardiorespiratory and metabolic measures such as VO2max and lactate threshold are only modest predictors of performance.    
  • 28.  In an attempt to produce a more holistic explanation, Noakes developed a model that consisted of five sub-models:  The classical 'cardiovascular / anaerobic' model as it stands now.  The energy supply / energy depletion model.  The muscle recruitment (central fatigue) / muscle power model.  The biomechanical model.  The psychological / motivational model.
  • 29. SOURCES OF ENERGY IN DIFFERENT ACTIVITIES
  • 30.
  • 31.  Any energy requiring processes invariably uses ATP as the prime source of energy.  At the start of an activity the initial source of energy is from ATP stores at the muscle crossbridges.  The amount of ATP in muscle is rather small.  This amount of ATP in muscle has been estimated to be sufficient to fuel around 3–5 seconds of maximal effort if ATP was the sole energy source.
  • 32.  The other immediate source of energy for high intensity exercise is that of creatine phosphate or phosphocreatine (PCr).  Creatine phosphate (PCr) rapidly replaces the ATP and becomes the next major source of energy.  This amount of PCr is sufficient to fuel maximal exercise solely for approximately 6– 8 s.
  • 33.  An essential store of carbohydrate fuel for both high- intensity exercise and prolonged activity.  Normal muscle glycogen stores have a concentration of 350 mM kg–1 dry muscle.  Can be increased significantly by a high carbohydrate diet and reduced significantly by repeated bouts of sprinting or a single prolonged bout of exercise or when on a low carbohydrate diet for around 2–4 days.
  • 34.  When muscle glycogen breaks down to produce energy, under the influence of the enzyme glycogen phosphorylase.  The process of breaking off glucose molecules from glycogen is known as glycogenolysis.  Glycolysis is a series of processes which takes place in the cytoplasm of cells resulting in the formation of two pyruvic acid molecules and ATP.
  • 35.  If the activity is intense, the pyruvic acid leads to the formation of lactic acid, although during steady-state exercise the majority of the pyruvic acid formed is broken down to produce carbon dioxide and water.
  • 36.  Glucose delivered to the muscle by blood may also act as a useful energy source during exercise.
  • 37. ROLE OF NUTRIENTS IN BIOENERGETICS
  • 38.  Proper nutrition forms the foundation for physical performance.  NUTRITION:- MACRONUTRIENTS & MICRONUTREINTS.
  • 39. Six broad categories of nutrients:  carbohydrates  fats  proteins  vitamins  minerals  water
  • 40.  Provide a rapid and readily available source of energy.  Found in three forms: monosaccharides, disaccharides, and polysaccharides.  Glucose is the most important simple sugar and is the only form of carbohydrate that can be directly metabolized to obtain energy.
  • 41.  Glycogen is not found in plants and is the polysaccharide form in which animals store carbohydrate.  During exercise, glucose molecules can be removed from glycogen in the liver by glycogenolysis, and released into the bloodstream to provide glucose as a metabolic substrate to other cells of the body.
  • 42.  Glucose and glycogen are the carbohydrates important for metabolism at rest and during exercise.  During exercise, muscle cells can obtain glucose by absorbing it from the bloodstream or by glycogenolysis from intramuscular glycogen stores.  glycogenolysis in the liver can maintain blood glucose levels during exercise and at times of rest between meals.
  • 43.  At rest, carbohydrate is taken up by the muscles and liver and converted into glycogen.  Glycogen can be used to form ATP and in the liver it can be converted into glucose and transported to the muscles via the blood. A heavy training session can deplete carbohydrate stores in the muscles and liver.  Carbohydrate can release energy much more quickly than fat.
  • 44.  Fat is stored predominantly as adipose tissue throughout the body and is a substantial energy reservoir.  It is less accessible for cellular metabolism as it must first be reduced from its complex form, triglyceride, to the simpler components of glycerol and free fatty acids.  So although fat acts as a vast stockpile of fuel, energy release is too slow for very intense activity.
  • 45.  Protein is used as a source of energy, particularly during prolonged activity.  however it must first be broken down into amino acids before then being converted into glucose. As with, fat, protein cannot supply energy at the same rate as carbohydrate.
  • 46.
  • 47.
  • 48.
  • 49.
  • 50.  Consuming mineral supplements above recommended levels on an acute or chronic basis does not benefit exercise performance or enhance trainin responsiveness.  Excessive water and electrolyte loss impairs heat tolerance and exercise performance and can trigger heat cramps, heat exhaustion, or heat stroke.
  • 51.  During practice or competition, an athlete sweats up to 5 kg of water.  This corresponds to about 8.0 g of salt depletion because each kilogram of sweat contains about 1.5 g of salt (of which 40% represents sodium).  Immediate replacement of water lost through sweating should become the overriding consideration.
  • 53.  Three factors determine the total daily energy expenditure (TDEE): 1. Resting metabolic rate 2. Thermogenic influence of consumed food 3. Energy expended during physical activity and recovery.
  • 54. A minimum energy requirement that sustains the body’s functions in the waking state.
  • 55.  Measuring oxygen uptake under the following three standardized conditions quantifies this requirement called the basal metabolic rate(BMR): 1. No food consumed for a minimum of 12 hours before measurement 2. No undue muscular exertion for at least 12 hours before measurement 3. Measured after the person has been lying quietly for 30 to 60 minutes in a dimly lit, temperature- controlled room.
  • 56.  It is measured under less strict conditions (e.g., 3 to 4 hours after a light meal without physical activity.)
  • 57.
  • 58.  Estimates of energy expenditure during rest and during exercise are often based on measurement of whole body oxygen consumption (VO2) and its caloric equivalent.  Under resting conditions, an average person consumes about 0.3 L of O2/min. or 18L of O2/hr. or 432L of O2/day.
  • 59.  One standardized measure of energy expenditure at rest is BMR. Factors affecting BMR are:  Gender  Body surface area  Age  Body temperature  Psychological stress  Hormones-thyroxine, epinephrine
  • 60.  BMR of a normal individual varies from 1200 to 2400 Kcal/day.  Energy expenditure for athletes engaged in intense training can exceed 10000Kcal/day.
  • 62.  Energy expenditure can be measured using one of the three approaches: indirect calorimetry  direct calorimetry  non-calorimetric techniques: Isotope dilution, doubly labelled water 
  • 63.
  • 64.  Essentials of Exercise Physiology, fourth edition, Victor L. Katch,William D. McArdle, Frank I. Katch.  Exercise Physiology Integrating Theory and Application, William J. Kraemer, Steven J. Fleck, Michael R. Deschenes.

Hinweis der Redaktion

  1. Bioenergetics is the part of Biochemistry concerned with the energy involved in growth, development and metabolism.
  2. If oxygen is available, a large amount of ATP is formed. This is known as aerobic glycolysis.If inadequate oxygen is available to meet the energy demands of the exercise task, then insufficient ATP is formed and lactic acid is a by-product of the process to generate more ATP. This is known as anaerobic glycolysis.
  3. Creatine phosphate (PCr) rapidly replaces the ATP and becomes the next major source of energy.The anaerobic breakdown of muscle glycogen through glycolysis to form ATP and lactic acid predominates after PCr, whilst aerobic processes predominate from approximately 60 s and beyond.