Presented at CeBiTec CLIB GC symposium, Bielefeld on March 11, 2013

1. Why Biotech faces the same
destiny as music industry
@pietervboheemen
#CeBiTec CLIB GC symposium, Bielefeld
22-3-2013 1

2. Out with the old, in with the…
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3. Social and Open Science
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4. New momentum in science
What happens to the knowledge you create?
www.thecostofknowledge.com
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5. New momentum in policy
Is Western Society tired of science?
Who needs science now that we have Dr. Google?
Knowledge, networks and nations – The Royal Society (2011)
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6. New momentum in business
Forcing Big Pharma to get even
bigger is not a strategy
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7. A comparison in innovation
Computers Biology
– 1980 – 1980
– 2010 – 2010
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8. New momentum in society
Genomics Health
Anno 2013 society is:
-Post industrial Science Diagnostics
-Networked Discovery
-Knowledge based
-International
-Open Home brewing
SynBio
-Empowered
Ecology Biology
DIY Design
Bio
Microbiology Citizen Science Bioremediation
Open Standards
Workshops Education
Self Teaching
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9. DIYBio: Hardware
GoGoFuge
OpenPCR.org BioCurious – DIY Bio Printer
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10. DIYBio: Education
Foo Camper’s Guide to Biological Engineering
Dutch DIYBio meetups and workshops - Gingko Bioworks
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11. DIYBio: Science
Brmlab (Prague) – Cognition experiments
Katherine Aull, MIT, 2009
MyDaughters DNA
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12. DIYBio: communities
BiologiGaragen
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13. DIYBio: Lab spaces
GenSpace, New York
La Paillasse, Paris
Waag Society, Amsterdam
IndieBiotech, Cork
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14. Waag Society Amsterdam
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15. Strong DIYBio tradition
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16. DIYBio in Germany
HannoverGEN
BioTinkering, Berlin
GreenPeace.de
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17. Why is IP important?
2010 iGEM Finalist
TU Delft iGEM Team 2010 – http://2010.igem.org/Team:TU_Delft
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18. iGEM Parts Registry License
http://creativecommons.org/licenses/by/3.0/
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19. iGEM Parts Registry License
• Open Source = Open?
Note: You must have an iGEM account and be a member
of a current iGEM team or lab group in order to obtain
parts from the Registry. If you would like to become an
iGEM lab see igem.org to join.
http://partsregistry.org/Help:Requesting_Parts
http://igem.org/Lab_Registration_Handbook
I can’t get my biobricks!?!
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20. New Registry on the Rise
DIYBio Europe Kick Off Meeting – Paris, December 2012
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21. How did DIYBio start
Amplino?
Dutch DIYBio Meetup, The Hague
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22. First shoe box PCR
Thermocycler
100
90
80
70
Temperature (C)
60
50
40
30
20
10
0
First Airplino Prototype 0 100 200 300 400 500
Time (sec)
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23. Rapid Prototyping
Early Amplino Prototype
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24. DIY environment
Bill and Melinda Gates Foundation – Flickr stream
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25. Grand Challenge, Big Impact
Lack of adequate diagnostics: who is right?
• Feachem, R. G. A. et al. Lancet (2010)
• Roll Back Malaria Progress & Impact Series:
Report 8 (WHO, 2011)
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26. Current bio innovation model
Top Down
Innovation
-High risk
-Big investments
-Low output Patent
Old world is based
on information
monopoly
Steinmetz and Spack BMC Neurology (2009)
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27. The problem with patents
• Limited use on global scale
– Especially developing world
• First to invent or First to file?
• Business models based on
patent trolling
• Product life cycles are
decreasing
• Costs (time, money, energy)
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28. Glimpse of the future
Imagine:
• Information and designs are
freely available & easily shared
• Fabrication is decentralized
• Science is democratized, f.e. DIY
diagnostics
Copyleft biopiracy is on the rise
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29. Information interpretation
Amplino Cloud Application - Crowsourcing disease surveillence
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30. Award winning vision
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31. Crossroad
2
Current knowledge society Keep calm & carry on
1
3
Backing winners, or challengers … or even losers?
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32. Concluding remarks
• #1: IP law must maximize benefit to
society
• Sharing is caring
• Openness is good for science, society
and business
• Protect what you share
– Always check the license of the journal or
database you submit to. Look for Creative
Commons or similar Share Alike licenses
• Collaboration leads to innovation
@pietervboheemen
@amplino
• Openness demands new business
www.amplino.com models
pieter.van.boheemen@amplino.com
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