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Team NRDC Presentation Series
       Board Room, NRDC, New Delhi
               Dated 08 July 2009


Business Prospects in
Agri Biopesticides and
     Biofertilizers
                     By ,
               Prabuddh Mishra
              Consultant ( BD II )
  National Research Development Corporation
Responsibilities

 Commercialization of Agri biotechnologies
 Evaluation of R&D Files from Agriculture
Companies
 Feasibility report
 Desk research for new technologies
 Proposals and technical reports
Methodologies in Business
         Development


Understanding the technology in commercial
parameters.
Desk research for new technologies
Desk research for business prospects for a
particular technology
Make pre feasibility report
Lessons learned

Be patient

 Make and maintain personal contacts with companies –
large and small

Set up open communications

Don’t fall in love with the technology

Offer solutions not technologies

Work on multiple projects simultaneously

Keep new projects in the “pipeline”
Agri Biotech era includes
     following technologies
Biofertilizers
Biopesticides
GMOS ( Seeds )
Plant Tissue Culture
Plant Based Phyto-chemicals
Algae Farming
Mushroom Farming
Animal /Plant ( ELISA KITS)
Biofuels
Biofertilizers
The term Biofertilizer is made up of two words .
“Bio” means living , and “Fertilizer” means a
product which provides nutrients in usable form

It contains mainly bacterial or fungal cells ,
which on application help in fixing or
solubilizing the nutrients presents in air or in soil
Biofertilizer and Organic manure are different
things
Present and last Nine year
Biofertilizer Production in India
    20000
    18000
    16000
    14000
    12000
    10000
     8000                                                                          Capacity
     6000                                                                          Production
     4000
     2000
        0
            19 19 19 19 19 19 19 20 20
            92- 93- 94- 95- 96- 97- 98- 01- 03-
            93 94 95 96 97 98 99 02 04

                                          Source :
                                   National Biofertilizer Development Centre Ghaziabad .
Zone wise Biofertilizer production
and consumption during 2005-06
   16000

   14000

   12000

   10000
                                   Production
   8000
                                   Consumption
   6000

   4000

   2000

      0
           East West North South



                                              Source :
                                       National Biofertilizer Development Centre Ghaziabad .
Future Prospects Biofertilizers

BCIL estimates about 344,800 tones of biofertilizers need in
India but production capacity is only 18,000 tones
Product quality should be good as end consumers are farmers
Organic farming is growing now days , so it’s a good demand in
this field , the present organically produced fruits and vegetables
are at the global level is valued at $ 27 million .
Indian biofertilizer companies are exporting 60 % of there
product and rest of 40 % is consume in India
Farmers in USA and Europe are well aware of Biofertilizer
Biopesticides
Biopesticides are naturally occurring substances that control pests
(biochemical pesticides), microorganisms that control pests
(microbial pesticides), and pesticidal substances produced by plants
containing added genetic material (plant-incorporated protectants)
also know as PIPs


Biopesticides, particularly microbial Biopesticides, have virtually all
the health safety and environmental properties that one would desire
in a pesticide



Microbial insecticides are come from naturally-occurring     bacteria,
fungi, viruses.
Biopesticides and their uses
Biopesticide     Source           Nature            Nature                                 Used against      Crops
Type                                                                                                         benefited
Natural          Plants       –   Biochemicals      Antifeedant,           Growth          Insect pest       Horticultural,
product          Neem                               regulation,   oviposition and                            plantation and
                 Vitex Garlic                       mating. disruption                                       plain crops
Microbials       Bacteria         Bacillus          Infection                              Insect pests
                                  thuringiensis(
                                  Bt)
                                  B.sphaericus, ,
                                  Pseudomonas       Antibiosis                             Disease

                 Virus            Nuclear           Infection       resulting        in    Insect pest
                                  Polyhedrosis      epizootics
                                  Viruses, GV,

                 Fungi            Beauveria,        Infection       resulting        in    Insect pests
                                  Metarhizium,      epizootics
                                  Paecilomyces,
                                  Nomuraea
                                  Trichoderma       Antagonism and Antibiosis              Fungal disease
                                  Gliocladium                                              of plants
                 Protozoa         Nosema,           Epizootics                             Insect pests.
                                  Thelohania,
                                  Vairimorpha
Pheromones       Pheromones       Biochemicals      Mating disruption, lure and kill, or   Insect pest
                                                    insect monitoring strategies
:
Genes       or   Desired          Biochemicals      Confer tolerance of herbicide          Insect pest and
Plant-           genes from a                       application or resistance to           disease
pesticide :      known                              attack by viruses or insects
                 source
Agriculture - The Changing facets


Past : Origin of Agriculture, Pesticides and Chemicalisation
– A History

Present : It has become customary out of necessity
conceived through individual thoughts to talk about
hazardous nature of chemical usage in agriculture and
compare it with biologicals as if the later have no ill-effect –
A view

Future : It was therefore thought fit at this juncture when
agriculture stands in the cross roads of chemicals and
biologicals to talk about a synergy of both – A concept
Availability of Biopesticides
  About 680 products of different microbials are
  currently available worldwide
  In India about 16 commercial preparations of Bt (
  Bacillus thuringiensis) , 38 fungal formulations based
  on Trichoderma,Metarhizium,Beauveria and about 45
  baculovirus-based formulations of Helicoverpa and
  spodoptera are available
  Microbial biopesticide are likely to replace at least 20 %
  of chemical pesticides
Source –DBT ,Delhi
Future business prospects -
             Biopesticides
  In India , the annual estimate damage ( 20%-30%)
  caused by pests ,diseases and weeds in various crops in
  the field and stored grains was Rs. 60-70 billion in 1983
  .
  The present price estimates is around 600 billion
  That’s why in 2005 ,pesticides worth Rs 27 billion were
  used in India
  Biopesticides are likely have a greater impact on the
  insecticide sector .
Source –DBT ,Delhi
Cont.1
  Some analyst believe that Biopesticides will account for
  15 % of the total insecticide market by 2010 .
  There is a growing demand for organically cultivated
  fresh and process fruits and vegetables .
  The current consumption of organically produced fruits
  and vegetables at the global level is valued at Rs 27
  billion .
Source –DBT ,Delhi
Cont.2
  The APEDA ( Agricultural Produces Export
  Development Agency ) of the Union Commerce
  Ministry had proposed to export organic food at a value
  of Rs 1500 billion annually during eleventh five year
  plan
  This would require enormous efforts to produce and
  use Biopesticides in the context of Integrated Pest
  Management .
  The growth rate of Biopesticides for the next ten years
  has been forecast at 10% to 15 % in contrast to 2.5 %
  for chemical pesticides
Source – DBT ,Delhi
GMOs ( Seeds )
Genetic Modified Organism ( GMO) is that in which
the basic genetic material ( DNA) has been artificially
altered or modified to improve the attributes or make
it perform new functions
Transgenic crops ( GMOs) really plays vital role to
sustain in tough climatic conditions like limited water ,
poor land condition ,drought ,heat and saline soil
conditions .
Bt cotton minimizes the use of chemical pesticides .
Potential benefits of Transgenic
                  Crops
                           Potential Benefits             Availability of
    Pest Resistance                                        more crops
Herbicide Resistance
Stress (Cold/drought)
      Tolerance                                           Better quality
   Delayed ripening      Improved       Cheaper Food        Products
                          Farming
                                         More Food
                                                          Improvement
 Increased Nutrition                                       In Health



                                                          Reduced use of
 Plant Pharmaceuticals                                 Chemicals & Herbicides
Global Transgenic Scenario
After successful implementation of bt gene in cotton ,
now days Seed companies are ready to launch Bt Brinjal
,Bt Cabbage and bt cauliflower .
This is again very helpful in minimizing use of chemical
pesticides in vegetables.
They are also involve in molecular marker based
breeding in crops to achieve traits like salt tolerance
,draught tolerance , anti allergic etc instead of existing
methods of field based conventional plant breeding
GMOs in USA
Source – Wikipedia
Biofuels

  Fossil fuels are depleting day by day and
are expected to finish in 2035
( Global report by NREL)
  Global warming and Climate change.
  India imports about 74% of liquid fuels
  To make India independent in liquid fuels
Types of Biofuels
Biodiesel
Bioethanol
Biogas
Jet fuel
Bio-Wax
Coal Bricks based on Husk
Syn gas from Biogasifires
Biocells
Research Scenario in Biofuel
          segment

Algae based Biodiesel and Jet fuel
Biorefinary
Cellulosic Bioethanol and Biobutanol
Biogas production from Jatropha seed cake
Other Phytochemicals which are useful in
pharmaceuticals industry .
Biorefinary (Technology Base )
Petroleum Refineries      Biorefinary
  a. Distillation           a. Biomass fractionation
  b. Thermo chemical        b. Industrial
  c. Process                Biotechnology
  d. Inorganic catalyst     c. Fermentation
                            d. Enzymes
                          (Biocatalysts)
Biorefinary products
Cellulosic bioethanol     Biplastics
Biodiesel                 Fine and bulk
Biogas                  chemicals
Syngas                    Oleo chemicals
Organic manure            Biowax
Jet biofuel               Glycerin
Algae Farming
Now days Algae also have many business prospects .
Cont.
We can also make biofertilizer from Blue Green
Algae .
Some companies are involve in making oleo
chemicals from algae which have pharmaceutical
value in international market
As a Nutraceutical product spirulina and
chlorella are cultivating commercially by big
players .
Plant based Phytochemicals
These are the chemicals derived from plants .
They have wide applications like bio-pesticides ,
larvicide's , medicines etc .
They are decomposable , so very good for environment
.
Recently we have a Plant based Mosquito Larvacide
technology from IARI ,Delhi .
NRDC Role in Agri Biotechnologies
 We are promoting these green technologies in
 India for the welfare of society .
 Recently we have given project to NICD,Delhi
 and IARI Pusa to generate bio-efficacy data for
 Neema Gel and Plant Based Larvacide
 technology .
  We are always looking for new biotechnologies
 to improve agriculture in India .
Achievements
Recently we have successfully transfer Mosquito
proof Desert Cooler Technology to five
companies .
We are in talk with Agro Chemicals Policy group
to implement Biofertilizer and Biopesticides in
chemical manufacturing companies .
Some Biofuels based companies also shown
their keen interest in green technologies .
THANKS …
In case of any queries
  please contact –



pmishra@nrdc.in

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Prabuddh Bd Ii Team Agri Biotech

  • 1. Team NRDC Presentation Series Board Room, NRDC, New Delhi Dated 08 July 2009 Business Prospects in Agri Biopesticides and Biofertilizers By , Prabuddh Mishra Consultant ( BD II ) National Research Development Corporation
  • 2. Responsibilities Commercialization of Agri biotechnologies Evaluation of R&D Files from Agriculture Companies Feasibility report Desk research for new technologies Proposals and technical reports
  • 3. Methodologies in Business Development Understanding the technology in commercial parameters. Desk research for new technologies Desk research for business prospects for a particular technology Make pre feasibility report
  • 4. Lessons learned Be patient Make and maintain personal contacts with companies – large and small Set up open communications Don’t fall in love with the technology Offer solutions not technologies Work on multiple projects simultaneously Keep new projects in the “pipeline”
  • 5. Agri Biotech era includes following technologies Biofertilizers Biopesticides GMOS ( Seeds ) Plant Tissue Culture Plant Based Phyto-chemicals Algae Farming Mushroom Farming Animal /Plant ( ELISA KITS) Biofuels
  • 6. Biofertilizers The term Biofertilizer is made up of two words . “Bio” means living , and “Fertilizer” means a product which provides nutrients in usable form It contains mainly bacterial or fungal cells , which on application help in fixing or solubilizing the nutrients presents in air or in soil Biofertilizer and Organic manure are different things
  • 7. Present and last Nine year Biofertilizer Production in India 20000 18000 16000 14000 12000 10000 8000 Capacity 6000 Production 4000 2000 0 19 19 19 19 19 19 19 20 20 92- 93- 94- 95- 96- 97- 98- 01- 03- 93 94 95 96 97 98 99 02 04 Source : National Biofertilizer Development Centre Ghaziabad .
  • 8. Zone wise Biofertilizer production and consumption during 2005-06 16000 14000 12000 10000 Production 8000 Consumption 6000 4000 2000 0 East West North South Source : National Biofertilizer Development Centre Ghaziabad .
  • 9. Future Prospects Biofertilizers BCIL estimates about 344,800 tones of biofertilizers need in India but production capacity is only 18,000 tones Product quality should be good as end consumers are farmers Organic farming is growing now days , so it’s a good demand in this field , the present organically produced fruits and vegetables are at the global level is valued at $ 27 million . Indian biofertilizer companies are exporting 60 % of there product and rest of 40 % is consume in India Farmers in USA and Europe are well aware of Biofertilizer
  • 10. Biopesticides Biopesticides are naturally occurring substances that control pests (biochemical pesticides), microorganisms that control pests (microbial pesticides), and pesticidal substances produced by plants containing added genetic material (plant-incorporated protectants) also know as PIPs Biopesticides, particularly microbial Biopesticides, have virtually all the health safety and environmental properties that one would desire in a pesticide Microbial insecticides are come from naturally-occurring bacteria, fungi, viruses.
  • 11. Biopesticides and their uses Biopesticide Source Nature Nature Used against Crops Type benefited Natural Plants – Biochemicals Antifeedant, Growth Insect pest Horticultural, product Neem regulation, oviposition and plantation and Vitex Garlic mating. disruption plain crops Microbials Bacteria Bacillus Infection Insect pests thuringiensis( Bt) B.sphaericus, , Pseudomonas Antibiosis Disease Virus Nuclear Infection resulting in Insect pest Polyhedrosis epizootics Viruses, GV, Fungi Beauveria, Infection resulting in Insect pests Metarhizium, epizootics Paecilomyces, Nomuraea Trichoderma Antagonism and Antibiosis Fungal disease Gliocladium of plants Protozoa Nosema, Epizootics Insect pests. Thelohania, Vairimorpha Pheromones Pheromones Biochemicals Mating disruption, lure and kill, or Insect pest insect monitoring strategies : Genes or Desired Biochemicals Confer tolerance of herbicide Insect pest and Plant- genes from a application or resistance to disease pesticide : known attack by viruses or insects source
  • 12. Agriculture - The Changing facets Past : Origin of Agriculture, Pesticides and Chemicalisation – A History Present : It has become customary out of necessity conceived through individual thoughts to talk about hazardous nature of chemical usage in agriculture and compare it with biologicals as if the later have no ill-effect – A view Future : It was therefore thought fit at this juncture when agriculture stands in the cross roads of chemicals and biologicals to talk about a synergy of both – A concept
  • 13. Availability of Biopesticides About 680 products of different microbials are currently available worldwide In India about 16 commercial preparations of Bt ( Bacillus thuringiensis) , 38 fungal formulations based on Trichoderma,Metarhizium,Beauveria and about 45 baculovirus-based formulations of Helicoverpa and spodoptera are available Microbial biopesticide are likely to replace at least 20 % of chemical pesticides Source –DBT ,Delhi
  • 14. Future business prospects - Biopesticides In India , the annual estimate damage ( 20%-30%) caused by pests ,diseases and weeds in various crops in the field and stored grains was Rs. 60-70 billion in 1983 . The present price estimates is around 600 billion That’s why in 2005 ,pesticides worth Rs 27 billion were used in India Biopesticides are likely have a greater impact on the insecticide sector . Source –DBT ,Delhi
  • 15. Cont.1 Some analyst believe that Biopesticides will account for 15 % of the total insecticide market by 2010 . There is a growing demand for organically cultivated fresh and process fruits and vegetables . The current consumption of organically produced fruits and vegetables at the global level is valued at Rs 27 billion . Source –DBT ,Delhi
  • 16. Cont.2 The APEDA ( Agricultural Produces Export Development Agency ) of the Union Commerce Ministry had proposed to export organic food at a value of Rs 1500 billion annually during eleventh five year plan This would require enormous efforts to produce and use Biopesticides in the context of Integrated Pest Management . The growth rate of Biopesticides for the next ten years has been forecast at 10% to 15 % in contrast to 2.5 % for chemical pesticides Source – DBT ,Delhi
  • 17. GMOs ( Seeds ) Genetic Modified Organism ( GMO) is that in which the basic genetic material ( DNA) has been artificially altered or modified to improve the attributes or make it perform new functions Transgenic crops ( GMOs) really plays vital role to sustain in tough climatic conditions like limited water , poor land condition ,drought ,heat and saline soil conditions . Bt cotton minimizes the use of chemical pesticides .
  • 18. Potential benefits of Transgenic Crops Potential Benefits Availability of Pest Resistance more crops Herbicide Resistance Stress (Cold/drought) Tolerance Better quality Delayed ripening Improved Cheaper Food Products Farming More Food Improvement Increased Nutrition In Health Reduced use of Plant Pharmaceuticals Chemicals & Herbicides
  • 19. Global Transgenic Scenario After successful implementation of bt gene in cotton , now days Seed companies are ready to launch Bt Brinjal ,Bt Cabbage and bt cauliflower . This is again very helpful in minimizing use of chemical pesticides in vegetables. They are also involve in molecular marker based breeding in crops to achieve traits like salt tolerance ,draught tolerance , anti allergic etc instead of existing methods of field based conventional plant breeding
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  • 22. GMOs in USA Source – Wikipedia
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  • 24. Biofuels Fossil fuels are depleting day by day and are expected to finish in 2035 ( Global report by NREL) Global warming and Climate change. India imports about 74% of liquid fuels To make India independent in liquid fuels
  • 25. Types of Biofuels Biodiesel Bioethanol Biogas Jet fuel Bio-Wax Coal Bricks based on Husk Syn gas from Biogasifires Biocells
  • 26. Research Scenario in Biofuel segment Algae based Biodiesel and Jet fuel Biorefinary Cellulosic Bioethanol and Biobutanol Biogas production from Jatropha seed cake Other Phytochemicals which are useful in pharmaceuticals industry .
  • 27. Biorefinary (Technology Base ) Petroleum Refineries Biorefinary a. Distillation a. Biomass fractionation b. Thermo chemical b. Industrial c. Process Biotechnology d. Inorganic catalyst c. Fermentation d. Enzymes (Biocatalysts)
  • 28. Biorefinary products Cellulosic bioethanol Biplastics Biodiesel Fine and bulk Biogas chemicals Syngas Oleo chemicals Organic manure Biowax Jet biofuel Glycerin
  • 29. Algae Farming Now days Algae also have many business prospects .
  • 30. Cont. We can also make biofertilizer from Blue Green Algae . Some companies are involve in making oleo chemicals from algae which have pharmaceutical value in international market As a Nutraceutical product spirulina and chlorella are cultivating commercially by big players .
  • 31. Plant based Phytochemicals These are the chemicals derived from plants . They have wide applications like bio-pesticides , larvicide's , medicines etc . They are decomposable , so very good for environment . Recently we have a Plant based Mosquito Larvacide technology from IARI ,Delhi .
  • 32. NRDC Role in Agri Biotechnologies We are promoting these green technologies in India for the welfare of society . Recently we have given project to NICD,Delhi and IARI Pusa to generate bio-efficacy data for Neema Gel and Plant Based Larvacide technology . We are always looking for new biotechnologies to improve agriculture in India .
  • 33. Achievements Recently we have successfully transfer Mosquito proof Desert Cooler Technology to five companies . We are in talk with Agro Chemicals Policy group to implement Biofertilizer and Biopesticides in chemical manufacturing companies . Some Biofuels based companies also shown their keen interest in green technologies .
  • 34. THANKS … In case of any queries please contact – pmishra@nrdc.in