Thyroid gland disorders
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Thyroid Hormone Disorders lecture :- -Thyroid gland & Thyroid hormones. -How does Thyroid hormone is formed ? -Regulation of secretion. -Hypothyroidism. -Treatment of hypothyroidism . -Administration of Levothyroxin. -Levothyroxin interactions. -Levothyroxin cautions. -Hyperthyroidism . -Symptoms & treatment of Hyperthyroidism. -Removal of part or all of the thyroid. -Blockade of hormone release . -Inhibition of thyroid hormone synthesis. -Mechanism of action of antithyroid. -Administration of antithyroid drugs. -Antithyroid drugs interactions. -Antithyroid drugs cautions. -General notes. -Practical notes on levothyroxin. -Practical notes on antithroid drugs. -Rapid review. -Test yourself.
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Thyroid gland disorders
- 2. Scientific Department Easy Pharmacology programme Present
- 3. Thyroid Hormone Disorders By Dr.MohamedAbdelrahman
- 4. The Lecture In Points
- 5. Thyroid gland & Thyroid hormones Visit video department on pharmacist development website
- 12. One form is Hashimoto’s thyroiditis, an autoimmune condition where antibodies are produced against thyroglobulin.PretibialMyxedema Waxy infiltrative plaques and edema,
- 16. Cholestyramine : May decrease thyroid hormone efficacy .
- 17. digitalis glycosides: May reduce effects of glycosides .
- 18. Fasting :Increases absorption of levothyroxin from GI tract.
- 20. Lactation :Minimal amounts excreted in breast milk.
- 28. Carbimazole and PTU are taken with meals (to minimize GI irritation) and with same amount of food to facilitate uniform absorption.
- 29. Encourage fluid intake of 3 to 4 L/day, unless contraindicated .
- 31. Beta blockers: Increased effects of beta blockers.
- 32. Digitalis glycosides: Increased digitalis levels, resulting in toxicity.
- 34. Lactation:Avoid nursing. However, if antithyroid drug is essential, PTU is preferred antithyroid agent while nursing.
- 35. Children:Hepatotoxicity has occurred in pediatric patients. Discontinue drug immediately if signs and symptoms of hepatic dysfunction develop
- 38. Caution patient not to take OTC or other prescribed medications without consulting physician .
- 39. Instruct patient to check pulse daily
- 40. Do not switch from one brand to another without comparison studies of bioavailability.Lipid lowering agents : rapid review
- 42. Advise patient to monitor weight at least 2 to 3 times/wk or per physician instruction, obtaining weight at same time, using same scale. Encourage patient to keep recorded chart.
- 43. Instruct patient to notify dentist or physician of drug regimen before surgical or dental procedures. secretion of thyroxin hormone : video
- 45. Caution patient not to take levothyroxine for weight control.
- 46. Explain that partial hair loss may be experienced by child in first few months of therapy but that this side effect is transient
- 47. In pregnancy, dosage may need to be increased to maintain TSH in desired range.Mechanism of action of fluoxetine (prozac) : video
- 49. For infants and children who cannot swallow intact tablets, crush proper dose tablet and suspend freshly crushed tablet in small amount offormula or water; give by spoon or dropper. Do not store suspension for any period of time. Crushedtablet may also be sprinkled over small amount of food (eg, cooked cereal, applesauce(
- 50. IV therapy is preferred in emergency treatment of myxedema coma.Understanding of diabetes : video
- 52. Inform patient that response to therapy may take months.
- 53. Instruct patient to report these symptoms to physician: rash, fever, sore throat, bruising or signs of infection or jaundice.
- 54. Advise patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness. Understanding of pneumonia : video
- 55. Rapid review
- 57. Hypothyroidism (Hyposecretion of thyroid hormone) causes cretinism in children ,and myxoedema in adults .
- 58. Hypothyroidism is treated by levothyroxine (T4) once daily. Understanding of allergy : video
- 60. Treatment can be by surgery or with drugs, for example carbimazole, to reduce the amount of thyroid hormone being produced.
- 61. Radioactive iodine is also used to treat thyrotoxicosis and to assess thyroid function.Gallstones : rapid review
- 62. Test yourself Pharmacist Development Enjoy learning www.pharmacist-development.com
- 64. A. tachycardia.
- 65. B. nervousness.
- 66. C. poor resistance to cold.
- 67. D. body wasting.
- 68. E. tremor. Understanding of myocardial infarction : video
- 70. A. It blocks the release of thyrotropin-releasing hormone.
- 71. B. It inhibits uptake of iodide by thyroid cells.
- 72. C. It prevents the release of thyroid hormone from thyroglobulin.
- 73. D. It blocks iodination and coupling of tyrosines in thyroglobulin to form thyroid hormones.
- 74. E. It blocks the release of hormones from the thyroid gland. Erectile dysfunction : video
- 77. B. Surgical removal of the thyroid gland
- 78. C. Iodide
- 80. E. carbimazoleUnderstanding of osteoporosis : video
- 82. Master (2008) .
- 83. Lippincott review in pharmacology .
- 84. Colour atlas of disease .
- 85. Drugs and Drugs: A Practical Guide to the Safe Use of Common Drugs in Adults .