Dr. Emil Chynn was the 1st eye surgeon in NYC to have LASIK himself (in 1999) but switched to the safer, noncutting SafeSight procedure in 2005 to avoid the night glare and dry eyes he and his patients had after LASIK. By avoiding cutting a flap, Dr. Chynn avoids cutting the corneal nerves, which causes dry eyes--so no dry eyes after LASEK!

1. Delighting irritated,
dry feeling eyes

2. Delighting eyes everywhere
As an expert in refractive eye care, Abbott Medical Optics Inc.
understands the importance of protecting the tear film from
drying conditions.
• The tear film is the first refractive surface of the eye. It provides a natural defence
against infection and is a highly effective lubricating device1
• Loss of moisture from the tear film can lead to reduced visual acuity as well as
irritated, uncomfortable eyes2
• The blink eye drop range has a solution to suit most of your customer needs,
from the lightly moisturising blink refreshing eye drops to the viscosity
enhanced longer lasting blink intensive tears. For the contact lens wearer there
is the specifically formulated blink contacts eye drops designed to keep eyes
feeling fresh and comfortable.

3. blink refreshing daily eye drops
• Instantly awakens tired feeling eyes
• Designed for those occasions when
your eyes natural moisture needs
a boost - such as after late nights
out or long periods of working at a
computer
blink contacts soothing eye drops
• Specifically formulated for contact
lens wearers
• The visco-elastic formulation
increases tear film stability for longer,
comfortable contact lens wear
blink intensive tears protective eye drops
• For longer lasting relief from irritated,
dry feeling eyes
• Formulated for those experiencing
more frequent feelings of irritated,
dry feeling eyes

4. Long lasting relief from
irritated, dry feeling eyes
blink intensive tears helps bring long lasting relief from irritated, dry
feeling eyes through its triple action formula
1 The hypotonic formulation lowers the tear film osmolarity3 to help bring
greater stability4
2 Contains a lubricating demulcent to soothe and protect
3 Viscosity enhanced for a longer lasting effect - can hold moisture in the eye
for more than 60 minutes with less blurring4,5

5. 1 Hypotonic blink intensive tears helps to stabilise the
tear film – breaking the negative cycle of ocular irritation
Inflammation can result in reduced
tear production so increasing tear Drying environments take
film osmolarity and potential ocular moisture from the eye
surface damage6 increasing tear film osmolarity7
Hypotonic blink
intensive tears helps
maintain the tear
film osmolarity
better than other
eye drops3
Results in
the release of
inflammatory
agents
Cycle of ocular irritation
Change in tear film osmolarity over a 30-day period3 (n = 20 per eye drop)
325
320
• An increased tear film osmolarity may
315
be linked to ocular surface damage
and dry feeling eyes6,8
310
mOsmol/l
• blink intensive tears significantly
305 reduced the tear film osmolarity over
the 30-day study period compared to
300 competitor drops3
295
290
Day 1 Day 1 Day 30 Day 30
before drop 5 minutes after before drop 5 minutes after
instillation drop instillation instillation drop instillation
17411 blink intensive tears 28811 Eye drop A 31211 Eye drop B
mOsmol/l mOsmol/l mOsmol/l
Normal tear film 308 mOsmol/l12

6. 2 Demonstrated to soothe dry, irritated eyes
• In a recent study of VDT users after 3 weeks of using blink intensive tears, a 32%
reduction in OSDI score was observed. In the same study the NIBUT was seen to
increase by 5 seconds during the study period.9
blink intensive tears were significantly more
soothing than a competitor eye drop4
80
70
69*
% of patients who ‘highly agreed’ that the
60
study eye drop was soothing
50
40
30
20
18 A significant fall in OSDI score for
10 blink intensive tears users9
40
0
blink intensive tears A competitor
35
* P = .021 eye drop
30
25
OSDI score
20
15
10
5
0
Baseline After 3 weeks

7. 3 Demonstrated to hold moisture in the eye for over
60 minutes for lasting comfort without blurring4,5
• In a further study, blink intensive tears users reported improved eye comfort over time
with an initial average improvement of 20%10
• After using blink intensive tears a statistically significant reduction in visual aberrations
was found11
Increasing comfort over time10
8
where 0 = poor and 10 = excellent
7
Comfort ratings
6
5
4
Start Day 7 Day 14 Day 21
• After just 21 days, 48% of blink intensive users reported an
improvement in vision quality10
• In a comparative study, a combined 89% of those using a
competitor eye drop experienced blurring compared to only
20% with blink intensive tears.4

8. blink eye drop range
blink blink blink
refreshing contacts blink-n-clean intensive tears
daily eye drops soothing eye drops eye drops protective eye drops
10ml multi-dose 10ml multi-dose 10ml multi-dose
Pack size 20 x 0.5ml 20 x 0.35ml 15ml multi-dose 20 x 0.4ml
single use vials single use vials single use vials
Polyvinyl Sodium Hydroxypropyl- Polyethylene glycol
Lubricant alcohol hyaluronate methylcellulose (PEG 400)
1.4% 0.15% (HMPC) 0.15% 0.25%
Viscosity Sodium hyaluronate
- - -
enhancer 0.2%
Tromethamine 1.2%
Cleaning agent - - -
Tyloxapol 0.025%
pH close to
Yes Yes Yes Yes
natural tears
Viscosity (CP) 3.612 5.5512 - 12.212
Osmolarity
30512 26712 - 17412
(mOsmol/l)
Buffer Phosphate Phosphate Phosphate Borate
Preservative Chlorite/peroxy OcuPure Polyhexamethylene OcuPure
(multi-dose only) compound (CPC) preservative biguanide preservative
10ml - 45 days 10ml - 45 days 10ml - 45 days
Discard Vials - Immediately Vials - Immediately 60 days Vials - Immediately
after use after use after use
References:
1. Craig J. Structure and function of the preocular tear film. In: Korb D, et al. Tear film: structure, function and clinical examination. Butterworth-Heinemann Ltd; 2002.
p18–50. 2. Reiger G. BJO 1992; 76: 157–8. 3. Albert T, Benelli U, Posarelli C. Evaluation of the change in tear osmolarity after using different eye drops. Manufacturer’s
showcase presentation. BCLA Conference & Exhibition 2009. 4. Thomas Kislan MD. Randomized, Cross-Over Evaluation of PEG-400 based Artificial Tear (blink) versus HP-Guar
based Artificial Tear (Systane) for Signs and Symptoms of Dry Eye. Hazleton Eye Specialists, PA. USA. Poster presented at the Annual Meeting of the American Academy of
Optometry, October 22-25,2008, Anaheim, CA. 5. Wavelength-Dependent Optical Interferometry Measurements of Change in Thickness of Apical Corneal Tear Film Following
Eye Drop Instillation S. Huth*, D. Tran*, C. Skotnitsky ‡, L. Lasswell‡, P. Mahmud†, T. Kim‡. *Advanced Medical Optics, Inc. (CR: E, P) ‡ Advanced Medical Optics, Inc. (CR: E)
†spherion, Inc., Santa Ana, CA (CR: N). POSTER ARVO. 6. THE OCULAR SURFACE. Dews. Management and Therapy. April. 2007; 5(2): 87. 7. Santosh Khanal et al. Dry Eye
Diagnosis. Ophthalmology and Visual Science. April 2008. 8. Katsuyama I, Arakawa T. A convenient rabbit model of ocular epithelium damage induced by osmotic dehydration.
J Ocul Pharmacol Ther. 2003 Jun;19(3):281-9. 9. Montani G, lndrio P. Effect of blink intensive and blink contacts on the Ocular Dryness in VDT Users. University of Salento.
Presentation at Assottica Meeting, Rome Nov. 2008. 10. Consumer assessment of blink intensive tears over time. A study commissioned by Abbott Medical Optics Inc. AMO data
on file. 11. Robert Montés-Micó, Alejandro Cerviño, Teresa Ferrer-Blasco, Santiago García-Lázaro, Susana Ortí-Navarro. Optical Quality of the Interface Air-tear Film Following
Instillation of Eye Drops in Dry Eyes. J Cataract Refract Surg June 2010. 12. Eye drop comparison. Data on File Abbott Medical Optics Inc.
OcuPure, blink and blink-n-clean are trademarks owned by or licensed to Abbott Laboratories, its subsidiaries or affiliates.
© 2010 Abbott Medical Optics Inc. 2010.10.25-CN2493 DoC:01Nov10.v6