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Medical Image
Processing-
Introduction
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Medical Imaging
• The study of medical imaging is concerned with
Interaction of all forms of radiation with
tissue.
• The development of appropriate technology to
extract clinically useful information, usually in the
form of an image from the observed
technology.
• Non-invasive visualization of internal organs, tissue,
etc.
– Is endoscopy an imaging modality?
• Image – a 2D signal f(x,y) or 3D f(x,y,z)
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Major Modalities
• Projection X-ray (Radiography)
• X-ray Computed Tomography (CT)
• Magnetic Resonance Imaging
• Ultrasound
• Nuclear Medicine ( PET)
• Magnetic Resonance Angiography
• Fundus Images
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
X-ray
• Image Formation
• A beam of X-rays is directed through a patient
onto a film.
• The film provides a measure of the ray attenuation in tissue.
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Sample X-ray Slices
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Computer Tomography
• Image Formation The object is viewed from a number of
different angles and then a cross-sectional image of it can be
computed (reconstructed).
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
3D Reconstruction in CT
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Sample CT Slices
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Magnetic Resonance
Imaging (MRI)
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Sample MRI
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Ultrasound
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Sample Ultrasound Image
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Positron Emission Tomography
(PET)
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Sample PET Images
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Magnetic Resonance Angiography
• Image Formation Imagine the blood vessels (moving spins)
using MRI scanner.
 PCA -(phase contract angiography)
 CEA -(contrast enhanced angiography)
 CTA -(computer tomography angiography)
 DSA- (digital subtraction angiography)
 TOF -(time-of-flight)
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Samples of Angiography
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Fundus photography
• Fundus photography (also called fundography[
) is the creation of a
photograph of the interior surface of the eye, including the retina, optic disc,
macula,
• Fundus photography is performed by a fundus camera, which basically
consists of a specialized low power microscope with an attached camera. and
posterior pole
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Sample Fundus Images
Fundus photography is used by optometrists,
ophthalmologists, and trained medical professionals for
monitoring progression of a disease, diagnosis of a disease
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Basic Medical Image
Processing System
Acquisition
Processing
Visualizing/Reporting
Pre processing
Segmentation
Detection
Analyzing
Diagnosis
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Acquisition of Images
• X-RAY
• MRI
• CT
• MRA
• PET
• MAMMOGRAM
• ULTRASOUND…..and More.
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Preprocessing of Images
• Filtering
• Image Denoising
• Image Registration
• Image enhancement
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
List of algorithms for
Preprocessing
• Median filter
• Mean filter
• Wavelet Based Denoising
• Wavelet based Image registration
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Segmentation
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
List of Segmentation
Algorithms
• K Means
• Fuzzy
• Neuro Fuzzy
• Neural Network based Segmentation
• Snake algorithm
• Thresholding based Segmentation
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Detection
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Analysis
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Classification/Diagnoses
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
List of Applications
• Medical Image Compression
• Medical Image Denosing
• Image Filtering
• Medical Image Retrieval
• Mammograms
• Tumor detection
• Medical Image fusion
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Medical Image Compression
Why Compress Medical Images ?
• Growing need for storage
• Efficient data transmission
• Telemedicine
• Tele-radiology applications
• Real time Tele-consultation.
• PACS (Picture archiving and communication
systems)
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Challenges unique to medical
images.
• Compression Algorithms
• Lossy / Lossless
• Medical Images should always be stored in
lossless format.
• Erroneous Diagnostics and its legal implications.
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Low motion areas  lossy
High motion areas  lossless
Future improvements
Lossless
Lossy
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Encoding using “slices” (group of macroblocks):
– First slice for high motion areas
– Second slice for low motion areas
Slices may be encoded at different rates
Future improvements
First slice
Second
slice
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Medical Image Fusion-
PET/CT
PET Image of the
Chest
CT Image of the
Chest
PET/CT Fused
Image of the
Chest
Multiple Modality images are registered and overlaid or
merged to provide additional information
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Medical Image Retrieval
What for ?
• Medical assistance
– Use of similar cases in order to assist medical
detection/diagnosis, treatment, …
• Difficult cases detection/diagnosis assistance
• Treatment choice assistance
 Education
• Better understanding of diseases and
phenomena using multiple similar
examples
• Better training by the recognition of similar
symptoms – different origins cases
• Updating and creating medical multimedia
atlases
 Research
• Medical Image Data mining
• New pathological trends,
• Extract new global characteristics by type of
population and geographic regions
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Medical Image Retrieval - Example
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
1. Differentiation of benign from malignant lessions
2. Staging of malignant disease
3. Differentiation of reccurent malignant disease
from therapy induced changes
4. Monitoring the response to therapy
Tumor Imaging
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
- Weight lost (15 kg)
- CT and endo ultrasound suspicion
of malignancy
- high risk patient undergoing dialysis
- PET negative
- clinical follow up without progression
Differentiation of benign from malignant lessions
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Differentiation of reccurent malignant disease from
therapy induced changes
MRI PET
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
• At least one microaneurysm - earliest clinically detectable lesion
• Retinal hemorrhages
• Hard or soft exudates
Diabetic Retinopathy-Ultrasound
Imaging
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Healthy Retina Diabetic Retinopathy
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Most of the Medical Image processing system consist of
1)Preprocessing
2)Enhancement
3)Filtering , Denoising and Morphological Operations
4)Segmentation
5)Detection
Conclusion
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
Thank you!Thank you!
Any doubts?
Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt
For more details
– www.pantechsolutions.net
– http://www.slideshare.net/pantechsolutions
– http://www.scribd.com/pantechsolutions
– http://www.youtube.com/pantechsolutions

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Medical Image Processing

  • 2. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Medical Imaging • The study of medical imaging is concerned with Interaction of all forms of radiation with tissue. • The development of appropriate technology to extract clinically useful information, usually in the form of an image from the observed technology. • Non-invasive visualization of internal organs, tissue, etc. – Is endoscopy an imaging modality? • Image – a 2D signal f(x,y) or 3D f(x,y,z)
  • 3. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Major Modalities • Projection X-ray (Radiography) • X-ray Computed Tomography (CT) • Magnetic Resonance Imaging • Ultrasound • Nuclear Medicine ( PET) • Magnetic Resonance Angiography • Fundus Images
  • 4. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt X-ray • Image Formation • A beam of X-rays is directed through a patient onto a film. • The film provides a measure of the ray attenuation in tissue.
  • 5. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Sample X-ray Slices
  • 6. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Computer Tomography • Image Formation The object is viewed from a number of different angles and then a cross-sectional image of it can be computed (reconstructed).
  • 7. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt 3D Reconstruction in CT
  • 8. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Sample CT Slices
  • 9. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Magnetic Resonance Imaging (MRI)
  • 10. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Sample MRI
  • 11. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Ultrasound
  • 12. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Sample Ultrasound Image
  • 13. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Positron Emission Tomography (PET)
  • 14. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Sample PET Images
  • 15. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Magnetic Resonance Angiography • Image Formation Imagine the blood vessels (moving spins) using MRI scanner.  PCA -(phase contract angiography)  CEA -(contrast enhanced angiography)  CTA -(computer tomography angiography)  DSA- (digital subtraction angiography)  TOF -(time-of-flight)
  • 16. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Samples of Angiography
  • 17. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Fundus photography • Fundus photography (also called fundography[ ) is the creation of a photograph of the interior surface of the eye, including the retina, optic disc, macula, • Fundus photography is performed by a fundus camera, which basically consists of a specialized low power microscope with an attached camera. and posterior pole
  • 18. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Sample Fundus Images Fundus photography is used by optometrists, ophthalmologists, and trained medical professionals for monitoring progression of a disease, diagnosis of a disease
  • 19. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Basic Medical Image Processing System Acquisition Processing Visualizing/Reporting Pre processing Segmentation Detection Analyzing Diagnosis
  • 20. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Acquisition of Images • X-RAY • MRI • CT • MRA • PET • MAMMOGRAM • ULTRASOUND…..and More.
  • 21. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Preprocessing of Images • Filtering • Image Denoising • Image Registration • Image enhancement
  • 22. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt List of algorithms for Preprocessing • Median filter • Mean filter • Wavelet Based Denoising • Wavelet based Image registration
  • 23. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Segmentation
  • 24. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt List of Segmentation Algorithms • K Means • Fuzzy • Neuro Fuzzy • Neural Network based Segmentation • Snake algorithm • Thresholding based Segmentation
  • 25. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Detection
  • 26. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Analysis
  • 27. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Classification/Diagnoses
  • 28. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt List of Applications • Medical Image Compression • Medical Image Denosing • Image Filtering • Medical Image Retrieval • Mammograms • Tumor detection • Medical Image fusion
  • 29. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Medical Image Compression Why Compress Medical Images ? • Growing need for storage • Efficient data transmission • Telemedicine • Tele-radiology applications • Real time Tele-consultation. • PACS (Picture archiving and communication systems)
  • 30. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Challenges unique to medical images. • Compression Algorithms • Lossy / Lossless • Medical Images should always be stored in lossless format. • Erroneous Diagnostics and its legal implications.
  • 31. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Low motion areas  lossy High motion areas  lossless Future improvements Lossless Lossy
  • 32. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Encoding using “slices” (group of macroblocks): – First slice for high motion areas – Second slice for low motion areas Slices may be encoded at different rates Future improvements First slice Second slice
  • 33. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Medical Image Fusion- PET/CT PET Image of the Chest CT Image of the Chest PET/CT Fused Image of the Chest Multiple Modality images are registered and overlaid or merged to provide additional information
  • 34. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Medical Image Retrieval What for ? • Medical assistance – Use of similar cases in order to assist medical detection/diagnosis, treatment, … • Difficult cases detection/diagnosis assistance • Treatment choice assistance  Education • Better understanding of diseases and phenomena using multiple similar examples • Better training by the recognition of similar symptoms – different origins cases • Updating and creating medical multimedia atlases  Research • Medical Image Data mining • New pathological trends, • Extract new global characteristics by type of population and geographic regions
  • 35. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Medical Image Retrieval - Example
  • 36. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt 1. Differentiation of benign from malignant lessions 2. Staging of malignant disease 3. Differentiation of reccurent malignant disease from therapy induced changes 4. Monitoring the response to therapy Tumor Imaging
  • 37. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt - Weight lost (15 kg) - CT and endo ultrasound suspicion of malignancy - high risk patient undergoing dialysis - PET negative - clinical follow up without progression Differentiation of benign from malignant lessions
  • 38. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Differentiation of reccurent malignant disease from therapy induced changes MRI PET
  • 39. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt • At least one microaneurysm - earliest clinically detectable lesion • Retinal hemorrhages • Hard or soft exudates Diabetic Retinopathy-Ultrasound Imaging
  • 40. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Healthy Retina Diabetic Retinopathy
  • 41. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Most of the Medical Image processing system consist of 1)Preprocessing 2)Enhancement 3)Filtering , Denoising and Morphological Operations 4)Segmentation 5)Detection Conclusion
  • 42. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt Thank you!Thank you! Any doubts?
  • 43. Technology beyond the Dreams™ Copyright © 2006 Pantech Solutions Pvt For more details – www.pantechsolutions.net – http://www.slideshare.net/pantechsolutions – http://www.scribd.com/pantechsolutions – http://www.youtube.com/pantechsolutions