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Evolutionary Symbolic Discovery for Bioinformatics Models

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Natalio Krasnogor
Natalio Krasnogor

I gave this talk at the Symbolic Regression Workshop that took place in GECCO 2010

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1 von 20
Evolutionary Symbolic Discovery for Bioinformatics, Systems and Synthetic Biology ,[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Synthesis of effective energy functions for PSP
Synthesis of effective Systems/Synthetic Biology models ,[object Object],[object Object],[object Object]
Motivation ,[object Object],[object Object],function f1(p1,p2,p3,p4) { if (p1<p2) and (rand<0.5) print p3 else print p4 } function f1(p1,p2,p3,p4) { if (p1<p2) RND print p3 RND else RND print p4 RND }
P Systems ,[object Object],[object Object],[object Object],[object Object],[object Object]
P Systems ,[object Object],[object Object],[object Object]
Modular Assembly of P Systems ,[object Object],[object Object],[object Object],[object Object]
Experimental Setup ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Target Models
Average Model Fit ,[object Object],[object Object]
Average Model Fit ,[object Object],For protein1, all algorithms have similar output to the target.
Average Model Fit ,[object Object]
Discussions & Conclusions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acknowledgements ,[object Object],[object Object],[object Object],[object Object],[object Object],/136 Integrated Environment Machine Learning & Optimisation Modeling & Model Checking Molecular Micro-Biology Stochastic Simulations Members of my team working on SB 2 EP/E017215/1 EP/H024905/1 BB/F01855X/1 BB/D019613/1 University of Nottingham Prof. M. Camara, Dr. S. Heeb, Dr. G. Rampioni, Prof. P. Williams Weizmann Institute of Science Prof. D. Lancet, Prof. I. Pilpel This Workshop Organisers You for listening!
Any Questions? ,[object Object],/136 Become a member and have access to a large international community of Synthetic Biologists

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