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Neonatal nutrition




              MILI SARKAR
                Dietician
Goals


• Ensure continuation of growth by giving
  enough calories
• Provide balance in fluid homeostasis
• keep electrolytes normal range
• Avoid imbalance in macro-nutrients
• Provide micro-nutrients and vitamins
General facts about neonatal fluid
           and nutrition
• Last trimester of pregnancy
  – Fat and glycogen storing
  – Iron reserves
  – Calcium and phosphorous deposits
• Premature babies more fluid (85%-95%),
  10% protein, 0.1% fat. No glycogen stores
• Insufficient protein & calories is life
  threatening to the sick
Guidelines fluid management
• 80 cc/kg/day, increase to 100-120cc/kg/d with
  increase IWL
• Increase to 100cc/kg/d 2nd day
  – add sodium 2-4 mEq/kg/d and K= 2 mEq/kg/d.
  – Calcium may be added
• after 2nd day adjust according to
  –   urine output 2-3cc/kg/hour with 110-140cc/kg/d
  –   Specific gravidity 1.008-1.012,
  –   watch weight change,
  –   total in/out
Nutritional pathway for premature
                infant
• Day1, parenteral glucose 5-7mg/kg/minute
  – Watch blood sugar
  – Electrolytes check at 24 hours
  – Consider trophic feeding
• Day2, TPN if not feeding
• Day 3 or more: enteral feeding slowly increased
  20cc/kg/day
   – 1.5kg= 30cc/day =2.5cc every 2 hours
• Day10-20, full nutrition
Energy use in body
•   Resting energy use 45 kcal/kg/d
•   Minimal activity       4 kcal/kg/d
•   Occasional cold stress 10 kcal/kg/d
•   Fecal loss of energy 15 kcal/kg/d
•   Growth 4.5kcal/gm      40-45 kcal/kg/d

• Total                   110-120 kcal/kg/d
Distribution of energy sources

•   Glucose   16.3gm = 55 kcal/kg/d…. 50%
•   Protein    3.1gm =12.5 kcal/kg/d…12%
•   Fat         4gm = 40 kcal/kg/d…38%
•   Total               108 kcal/kg/d
Total parenteral nutrition (TPN)
• growth of 10-15gm/kg/day weight gain
  – 3gm/kg/d protein (amino acid)
  – 3gm/kg/d fat (Fatty acid)
  – 16gm/kg/d Dextrose 10-25%
    (carbohydrate)
• this will give100-120 k. calories /kg/day
others

• Minerals
  – Zinc, copper, molybdenum, chromium,
    selenium
  – Calcium, phosphorous, Magnesium
  – Na, K
• Vitamins
  – Fat soluble
  – Water soluble
Biochemical testing for patient on
                  TPN
•   Urine glucose
•   Triglyceride
•   BUN, Albumin
•   Ca, P, Mg, creatinine, Na, Cl, CO2
•   direct (conjugated) bilirubin, ALT
•   Trace element level
Complication of TPN

•   Infiltration under skin
•   Infection
•   Liver dysfunction
•   Renal overload
Feeding development
• Swallowing first detected at 11 weeks
• Sucking reflex at 24 weeks
• Coordinated suck-swallowing not
  present till 32-34 weeks
• Swallowing to coordinate with respiration
  – Respiration>60-80 NG feeding
  – Respiration>80 high risk for aspiration (NPO)
WHO – BREAST FEEDING
            Recommendation
The World Health Organization recommends
exclusive breastfeeding for the first six months
of life, with solids gradually being introduced
around this age when signs of readiness are
shown. Supplemented breastfeeding is
recommended until at least age two, as long
as mother and child wish.
Methods of feeding
• Oral feeding
  – >32 weeks
  – Respiration<60-80
  – Try 20 minutes
• Naso-gastric (NG) feeding bolus
• NG feeding continuous
• trans-pyloric
• Gastrostomy feeding
Trophic Feeding
• Keeping infant fasting (NPO)
  – Decrease in intestinal mass
  – Decrease in mucosal enzyme
  – Increase in gut permeability
• Trophic feeding:
  – small amount of feeding to prepare the intestine
  – release enteric hormones, better tolerance to feeds
Enteral feeding
• 40-45% of calories are coming from
  carbohydrates (Lactose or glucose
  polymer)
• Protein requirement of infant is 2.2-4.0
  gm/kg/d
• Protein is whey predominant 60:40
Breast feeding
• after delivery baby has metabolic reserves
     • Hepatic glycogen
     • Brown fat
     • Extracellular and extra vascular water
• milk production is stimulated
• Try to get baby onto the breast within first
  1-2 hours of life
• Colestrum ; high in protein &
  immunoglobulin
Breast feeding
• Q2-3 hours = 8-12 feeds per day
  – Quicker gastric emptying
  – frequent breast stimulation and emptying increase milk supply
  – Watch for feeding cues
• Duration
  – 10 minutes or longer
  – As long as swallowing continues
• Cluster feeds is normal
• Growth spurts
  – Baby may feeds more frequently for 1-2 days
  – Many growth spurts at 2wks, 6, wks, 2-3 months, and 5-6
    months they feed more during them
Breast feeding
• Ineffective if baby sucks from nipple only
• Nipple and areola must be drawn deeply
  into baby’s mouth
• Listen for infant swallowing
  – DOL#1: intermittent swallows
  – DOL#2 on: 1 swallow : 1-3 jaw excursions
Maternal factor of low milk
• Gestational diabetes
• Hypothyroid
• Retained placental fragments
• Dehydration, hemorrhage, hypertension, infection
• Previous breast surgery
• Lack of prenatal engorgement
• Psychosocial
   –   Previous unsatisfactory experience
   –   Lack of partner support
   –   Post-partum depression
   –   Separation from infant
Milk is what you eat
• Mom’s need extra 500kcal/day if breast
  feeding
• Caffeine
  – Limit to 1-2 cups/day
  – Babies may become overstimulated, fussy


• Spicy and gassy foods reflects
Infant illness that affect breast
                   feeding
• Prematurity
     – Co-ordinated suck-swallow-breathing reflexes at 32-34 weeks
• SGA, IUGR
• Twins
•   Cleft lip and Palate, Micrognathia, Ankyloglossia, Macroglossia
•   Jaundice
•   Neuromotor problems
•   Birth asphyxia
•   Cardiac lesions
•   Infection
•   Surgical problems
Do I have to wake my baby to
               feed?
• Should wake baby during first 2-3 weeks
  while milk supply is being established
• Once milk supply good and baby back to
  birth weight can allow baby to go 5 hours
  during a 24 hour period without a feed
• If milk supply decreasing should reinstitute
  night time feed
Is my milk enough???
• 8-12 feeds per day to 6-8 weeks of age
• Frequent swallowing
• Adequate urine output (2-6 times/day)
• Adequate stooling
•   Yellow stools by DOL#4
•   Weight loss no greater than 8% of BWT
•   Weight gain 15-30 grams/day
•   Good skin turger, moist mucous membranes
•   Contentment 1.5-2 hours after feeds
Enough milk
• Breasts feel full before and softer after
  feeds
• Milk leaks from contralateral breast during
  suckling
• Sensation of milk ejection ⇒ pins and
  needles
• Absent nipple trauma and pain
• Profound state of relaxation in mom during
  suckling
Human milk
• Human milk is Ideal food for full term
  infant
• Inadequate components for premature
  infant <1500gm (human milk fortifier
  needed to be added)
  – Protein
  – Vitamin D
  – Calcium
  – Phosphorous
  – Sodium
Breast feeding


• Foremilk
• Hind milk
Nonnutritive sucking
• Pacifier
  – In premature
     • ?/ no effect (wt gain, hospitalization, improved
       oxygenation, faster oral feeding)
• May give infant comfort and calm more
  quickly
• In term infant nipple confusion with bottle
  and pacifier against breast feeding
Breast milk substitutes
Exactly there is no equal substitute for
 Mothers Milk
Occasionally the artificial milk have to be
 given to adopted babies or those who lost
 mother .
Liquid milk consumed by the family should
 be utilized, the powder should be strongly
 discouraged.
Premature formulas
• lack natural standard
• 50% lactose and rest glucose polymer
• Protein
  – 150% in amount of term formula
  – Whey predominant
• Fat 50% LCT 50%MCT.
• Higher Ca, P, higher Ca : P ratio of 2:1
• Long chain polyunsaturated fatty acids
Standard infant formula
• 100% lactose
• Fat is all long chain triglyceride
• Protein is whey 60%, casein 40%
• Iron fortified 12mg/liter and low iron versus
  low 1.5mg/liter (should not give it)
• Ready to feed or prepare from powder
Soy formulas
• Lactose free
  – Primary and secondary lactase defeciency
  – Galactosemia
• Carbohydrate is sucrose or corn syrup
• Fat is vegetable oil such as coconut oil
• Not recommended in very low birth weight
  infant related to weight gain and
  osteopenia.
Case two
• 3.5 Kg mother wants to breast feed her
  infant. She is primi-gravida
  – Is small amount of milk in first 3ds enough
  – How to encourage her to continue breast
    feeding
  – Signs of successful breast feeding
  – For how long breast feeding to continue
  – Discuss AAP guideline
  – Baby jaundice at 2 weeks
Case 3
• 1.4 kg baby born at 30 week and has RDS
  – Discuss fluid management in first 3 days
  – How to feed him
    •   Amount
    •   Rate of increase
    •   Type of formula
    •   Risks of fast feeding
Conclusion
I have insufficient milk to feed my child" or "my baby is
having an aversion to breast. He simply turns his face
away "Scientists have proven from time to time that these
statements are not true.
Many mothers expect that breast milk must flow just like
bottle milk.
THEY OFTEN FORGET THAT BOTTLE MILK IS
LIFELESS & BREAST Milk ARE FULL OF LIFE.
"IF THERE IS A WILL THERE IS MILK ALWAYS" is a
                                           ALWAYS
medical dictum
The end !

Thank you for
completing this
module

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Neonatal Nutrition Essentials

  • 1. Neonatal nutrition MILI SARKAR Dietician
  • 2. Goals • Ensure continuation of growth by giving enough calories • Provide balance in fluid homeostasis • keep electrolytes normal range • Avoid imbalance in macro-nutrients • Provide micro-nutrients and vitamins
  • 3. General facts about neonatal fluid and nutrition • Last trimester of pregnancy – Fat and glycogen storing – Iron reserves – Calcium and phosphorous deposits • Premature babies more fluid (85%-95%), 10% protein, 0.1% fat. No glycogen stores • Insufficient protein & calories is life threatening to the sick
  • 4. Guidelines fluid management • 80 cc/kg/day, increase to 100-120cc/kg/d with increase IWL • Increase to 100cc/kg/d 2nd day – add sodium 2-4 mEq/kg/d and K= 2 mEq/kg/d. – Calcium may be added • after 2nd day adjust according to – urine output 2-3cc/kg/hour with 110-140cc/kg/d – Specific gravidity 1.008-1.012, – watch weight change, – total in/out
  • 5. Nutritional pathway for premature infant • Day1, parenteral glucose 5-7mg/kg/minute – Watch blood sugar – Electrolytes check at 24 hours – Consider trophic feeding • Day2, TPN if not feeding • Day 3 or more: enteral feeding slowly increased 20cc/kg/day – 1.5kg= 30cc/day =2.5cc every 2 hours • Day10-20, full nutrition
  • 6. Energy use in body • Resting energy use 45 kcal/kg/d • Minimal activity 4 kcal/kg/d • Occasional cold stress 10 kcal/kg/d • Fecal loss of energy 15 kcal/kg/d • Growth 4.5kcal/gm 40-45 kcal/kg/d • Total 110-120 kcal/kg/d
  • 7. Distribution of energy sources • Glucose 16.3gm = 55 kcal/kg/d…. 50% • Protein 3.1gm =12.5 kcal/kg/d…12% • Fat 4gm = 40 kcal/kg/d…38% • Total 108 kcal/kg/d
  • 8. Total parenteral nutrition (TPN) • growth of 10-15gm/kg/day weight gain – 3gm/kg/d protein (amino acid) – 3gm/kg/d fat (Fatty acid) – 16gm/kg/d Dextrose 10-25% (carbohydrate) • this will give100-120 k. calories /kg/day
  • 9. others • Minerals – Zinc, copper, molybdenum, chromium, selenium – Calcium, phosphorous, Magnesium – Na, K • Vitamins – Fat soluble – Water soluble
  • 10. Biochemical testing for patient on TPN • Urine glucose • Triglyceride • BUN, Albumin • Ca, P, Mg, creatinine, Na, Cl, CO2 • direct (conjugated) bilirubin, ALT • Trace element level
  • 11. Complication of TPN • Infiltration under skin • Infection • Liver dysfunction • Renal overload
  • 12. Feeding development • Swallowing first detected at 11 weeks • Sucking reflex at 24 weeks • Coordinated suck-swallowing not present till 32-34 weeks • Swallowing to coordinate with respiration – Respiration>60-80 NG feeding – Respiration>80 high risk for aspiration (NPO)
  • 13. WHO – BREAST FEEDING Recommendation The World Health Organization recommends exclusive breastfeeding for the first six months of life, with solids gradually being introduced around this age when signs of readiness are shown. Supplemented breastfeeding is recommended until at least age two, as long as mother and child wish.
  • 14. Methods of feeding • Oral feeding – >32 weeks – Respiration<60-80 – Try 20 minutes • Naso-gastric (NG) feeding bolus • NG feeding continuous • trans-pyloric • Gastrostomy feeding
  • 15. Trophic Feeding • Keeping infant fasting (NPO) – Decrease in intestinal mass – Decrease in mucosal enzyme – Increase in gut permeability • Trophic feeding: – small amount of feeding to prepare the intestine – release enteric hormones, better tolerance to feeds
  • 16. Enteral feeding • 40-45% of calories are coming from carbohydrates (Lactose or glucose polymer) • Protein requirement of infant is 2.2-4.0 gm/kg/d • Protein is whey predominant 60:40
  • 17. Breast feeding • after delivery baby has metabolic reserves • Hepatic glycogen • Brown fat • Extracellular and extra vascular water • milk production is stimulated • Try to get baby onto the breast within first 1-2 hours of life • Colestrum ; high in protein & immunoglobulin
  • 18. Breast feeding • Q2-3 hours = 8-12 feeds per day – Quicker gastric emptying – frequent breast stimulation and emptying increase milk supply – Watch for feeding cues • Duration – 10 minutes or longer – As long as swallowing continues • Cluster feeds is normal • Growth spurts – Baby may feeds more frequently for 1-2 days – Many growth spurts at 2wks, 6, wks, 2-3 months, and 5-6 months they feed more during them
  • 19. Breast feeding • Ineffective if baby sucks from nipple only • Nipple and areola must be drawn deeply into baby’s mouth • Listen for infant swallowing – DOL#1: intermittent swallows – DOL#2 on: 1 swallow : 1-3 jaw excursions
  • 20. Maternal factor of low milk • Gestational diabetes • Hypothyroid • Retained placental fragments • Dehydration, hemorrhage, hypertension, infection • Previous breast surgery • Lack of prenatal engorgement • Psychosocial – Previous unsatisfactory experience – Lack of partner support – Post-partum depression – Separation from infant
  • 21. Milk is what you eat • Mom’s need extra 500kcal/day if breast feeding • Caffeine – Limit to 1-2 cups/day – Babies may become overstimulated, fussy • Spicy and gassy foods reflects
  • 22. Infant illness that affect breast feeding • Prematurity – Co-ordinated suck-swallow-breathing reflexes at 32-34 weeks • SGA, IUGR • Twins • Cleft lip and Palate, Micrognathia, Ankyloglossia, Macroglossia • Jaundice • Neuromotor problems • Birth asphyxia • Cardiac lesions • Infection • Surgical problems
  • 23. Do I have to wake my baby to feed? • Should wake baby during first 2-3 weeks while milk supply is being established • Once milk supply good and baby back to birth weight can allow baby to go 5 hours during a 24 hour period without a feed • If milk supply decreasing should reinstitute night time feed
  • 24. Is my milk enough??? • 8-12 feeds per day to 6-8 weeks of age • Frequent swallowing • Adequate urine output (2-6 times/day) • Adequate stooling • Yellow stools by DOL#4 • Weight loss no greater than 8% of BWT • Weight gain 15-30 grams/day • Good skin turger, moist mucous membranes • Contentment 1.5-2 hours after feeds
  • 25. Enough milk • Breasts feel full before and softer after feeds • Milk leaks from contralateral breast during suckling • Sensation of milk ejection ⇒ pins and needles • Absent nipple trauma and pain • Profound state of relaxation in mom during suckling
  • 26. Human milk • Human milk is Ideal food for full term infant • Inadequate components for premature infant <1500gm (human milk fortifier needed to be added) – Protein – Vitamin D – Calcium – Phosphorous – Sodium
  • 28. Nonnutritive sucking • Pacifier – In premature • ?/ no effect (wt gain, hospitalization, improved oxygenation, faster oral feeding) • May give infant comfort and calm more quickly • In term infant nipple confusion with bottle and pacifier against breast feeding
  • 29. Breast milk substitutes Exactly there is no equal substitute for Mothers Milk Occasionally the artificial milk have to be given to adopted babies or those who lost mother . Liquid milk consumed by the family should be utilized, the powder should be strongly discouraged.
  • 30. Premature formulas • lack natural standard • 50% lactose and rest glucose polymer • Protein – 150% in amount of term formula – Whey predominant • Fat 50% LCT 50%MCT. • Higher Ca, P, higher Ca : P ratio of 2:1 • Long chain polyunsaturated fatty acids
  • 31. Standard infant formula • 100% lactose • Fat is all long chain triglyceride • Protein is whey 60%, casein 40% • Iron fortified 12mg/liter and low iron versus low 1.5mg/liter (should not give it) • Ready to feed or prepare from powder
  • 32. Soy formulas • Lactose free – Primary and secondary lactase defeciency – Galactosemia • Carbohydrate is sucrose or corn syrup • Fat is vegetable oil such as coconut oil • Not recommended in very low birth weight infant related to weight gain and osteopenia.
  • 33. Case two • 3.5 Kg mother wants to breast feed her infant. She is primi-gravida – Is small amount of milk in first 3ds enough – How to encourage her to continue breast feeding – Signs of successful breast feeding – For how long breast feeding to continue – Discuss AAP guideline – Baby jaundice at 2 weeks
  • 34. Case 3 • 1.4 kg baby born at 30 week and has RDS – Discuss fluid management in first 3 days – How to feed him • Amount • Rate of increase • Type of formula • Risks of fast feeding
  • 35. Conclusion I have insufficient milk to feed my child" or "my baby is having an aversion to breast. He simply turns his face away "Scientists have proven from time to time that these statements are not true. Many mothers expect that breast milk must flow just like bottle milk. THEY OFTEN FORGET THAT BOTTLE MILK IS LIFELESS & BREAST Milk ARE FULL OF LIFE. "IF THERE IS A WILL THERE IS MILK ALWAYS" is a ALWAYS medical dictum
  • 36. The end ! Thank you for completing this module