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Imaging                                                                          IMAGING CENTRE
  Redefined
     Vol : 4 Iss : 3
                                                             The Sound Of Babies…
                          R

                                                               11 – 14 week USG!
           Excellence in                                       FIRST TRIMESTER ULTRASOUND SCREENING
          ULTRASOUND
            @ VITAL                                       11-14 WK SCAN is examination of the fetal profile in its
                                                          first trimester to screen for Downs syndrome with the use
At VITAL Imaging a dedicated protocol for                 of maternal age & nuchal translucency (NT). A blood test
First Trimester Nuchal Translucency                       (free beta-HCG & PAPP-A) also can be added to the
Measurement laid by the Fetal Medicine                    screening as it is associated with a higher detection rate &
Foundation is followed for the                            lower false positive rate compared to triple screening.
11-14 wk Screening.
                                                          Extensive research has now established that
                                                          screening by NT can detect about 80% of affected
In the 1st Trimester, Nuchal Translucency
                                                          fetuses for a screen positive rate of 5%. The
is taken in the sagittal plane of the fetus.
                                                          combination of NT & maternal serum free Ăź-hCG &
In the 2nd Trimester, Nuchal Fold is taken
                                                          PAPP-A improves the detection to 90%.
in the transverse plane of the fetus.

                                                                                           MEASUREMENT OF NT
Who should be offered 11-14 wk scan?
It should be offered to all pregnant women who are
                                                                                           CRL 45-84 mm
at a high risk as well as low risk for the disorders to
                                                                                           MID – SAG View, Neutral
be screened. Therefore, the screening program
                                                                                           position
described here is also for women who are under 35
                                                                                           Image Size – Head & thorax
years of age at the time of delivery & who do not
                                                                                           Widest lucency away from
have a positive history of a chromosomal
                                                                                           amnion
abnormality.


                                                                                           NASAL BONE
                                                                                           CRL 45-84 mm
        VITAL PREGNANCY                                                                    MID – SAG VIEW
                                                                                           Image Size – Head & thorax
     SONOGRAPHY PACKAGES
                                                                                           Equal sign- Two parallel
                                                                                           horizontal lines:
      DATING SCAN at 6 – 8 wks                                                             Top line – Skin
                                                                                                 Bottom line – Nasal bone
      FIRST TRIMESTER at 11 – 14 wks                                                             Third line – Tip of the nose
      SCREENING
                                                          Optimum 1st trimester screening test is provided by
      ANOMALY SCAN at 18 - 20 wks
                                                          a combination of:
                                                              • Age of the mother
      3D / 4D SCAN at 18 - 20 wks
                                                              • Nuchal Translucency measurement
                                                              • Nasal Bone (Present / Absent)
      3D / 4D SCAN at 28 - 34 wks
                                                              • Free b-HCG and PAPP-A levels in the mother
                                                              • Tricuspid Regurgitation (Present / Absent)
      COLOUR DOPPLER at 30 - 40 wks
                                                              • Physical abnormality (Present / Absent)

                                                                                                         Pg: 1
Website: www.vitalradiology.com                               Ph: 26301184            EXCELLENCE IN IMAGING…
Blog: http://soundofbabies.blogspot.com                             26301185                     ALWAYS…
Imaging
                                                                                             IMAGING CENTRE
Redefined
   Vol : 4 Iss : 3
                                                               The Sound Of Babies…
                                                                11 – 14 week USG!
NUCHAL TRANSLUCENCY (NT) -                                                            NASAL BONE (NB) -
                                                                                      The presence of fetal nasal bone is
NT is the sonographic appearance of subcutaneous
                                                                                      reassuring & is particularly useful for
accumulation of fluid behind the fetal neck in first trimester.
                                                                                      patients with risks between 1 in 150 & 1
         The term translucency is used, irrespective of
                                                                                      in 300 who are traditionally classified as
         whether it is septated or not & whether it is confined
                                                                                      screen positive, but with the presence of
         to the neck or envelopes the whole fetus.                                    the nasal bone confirmed, may be
         The incidence of chromosomal & other abnormalities                           sufficiently reassured.
         is related to the size, rather than the appearance.
         During the second trimester, the translucency                                An absent nasal bone will increase
         usually resolves &, in a few cases, it evolves into                          dramatically the risk for Trisomy 21, but
         either nuchal edema or cystic hygromas with or                               our advice is that such patients are
                                                                                      rescanned in one week & action is only
         without generalized hydrops.
                                                                                      taken at that point if there is persistence
         NT increases with the gestational age, approx
                                                                                      of the absence of the nasal bone.
         17% per wk.
                                                                                      At 11–14 wks the nasal bone is not
NT is increased in fetuses with
                                                                                      visible by USG in about 60–70% of
                                                                                      fetuses with trisomy 21 & in about 2% of
         Chromosomal & other abnormalities                                            chromosomally normal fetuses.
         (Trisomies 21, 18 & 13, Triploidy & Turner’s syndrome)                       .
         Cardiac defects(septal defects)
         Pulmonary (diaphragmatic hernia)
         Renal & abdominal wall defects
         Certain genetic syndromes & perinatal risks

METHOD OF SCREENING                                        SENSITIVITY (%)
Maternal age (MA)                                                           30
MA & maternal triple marker at 15–18 weeks                               50–70
MA & fetal NT at 11–14 wks                                               70–80
MA & fetal NT, maternal free b-hCG & PAPP-A
at 11–14 wks                                                             85–90
MA & fetal NT & fetal NB at 11–14 wks                                       90
MA & fetal NT, NB, maternal free b-hCG & PAPP-A
at 11–14 wks                                                                     95   (For Private Circulation Only)
                                                                                      For more information, questions or
(NT: Nuchal Translucency, NB: Nasal Bone, b-hCG: human chorionic gonadotropin,
                                                                                      Suggestions please call us on 26301184 / 85
PAPP-A: pregnancy-associated plasma protein A)
                                                                                      Or email us at newsletter@vitalradiology.com

                                                                                                                         Pg: 2

MULTI SLICE CT SCAN                       DIGITAL X-RAY            PATHOLOGY                                24 x 7
MULTI SLICE SONOGRAPHY                    DIGITAL OPG              ECG                             VITAL MOBILE IMAGING!
3D / 4D SONOGRAPHY                        2D ECHO                  PFT
COLOR DOPPLER                             STRESS TEST              HEALTH CHECK UPS                       Ph: 26301184 / 85

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11-14 Wks Sonography

  • 1. Imaging IMAGING CENTRE Redefined Vol : 4 Iss : 3 The Sound Of Babies… R 11 – 14 week USG! Excellence in FIRST TRIMESTER ULTRASOUND SCREENING ULTRASOUND @ VITAL 11-14 WK SCAN is examination of the fetal profile in its first trimester to screen for Downs syndrome with the use At VITAL Imaging a dedicated protocol for of maternal age & nuchal translucency (NT). A blood test First Trimester Nuchal Translucency (free beta-HCG & PAPP-A) also can be added to the Measurement laid by the Fetal Medicine screening as it is associated with a higher detection rate & Foundation is followed for the lower false positive rate compared to triple screening. 11-14 wk Screening. Extensive research has now established that screening by NT can detect about 80% of affected In the 1st Trimester, Nuchal Translucency fetuses for a screen positive rate of 5%. The is taken in the sagittal plane of the fetus. combination of NT & maternal serum free Ăź-hCG & In the 2nd Trimester, Nuchal Fold is taken PAPP-A improves the detection to 90%. in the transverse plane of the fetus. MEASUREMENT OF NT Who should be offered 11-14 wk scan? It should be offered to all pregnant women who are CRL 45-84 mm at a high risk as well as low risk for the disorders to MID – SAG View, Neutral be screened. Therefore, the screening program position described here is also for women who are under 35 Image Size – Head & thorax years of age at the time of delivery & who do not Widest lucency away from have a positive history of a chromosomal amnion abnormality. NASAL BONE CRL 45-84 mm VITAL PREGNANCY MID – SAG VIEW Image Size – Head & thorax SONOGRAPHY PACKAGES Equal sign- Two parallel horizontal lines: DATING SCAN at 6 – 8 wks Top line – Skin Bottom line – Nasal bone FIRST TRIMESTER at 11 – 14 wks Third line – Tip of the nose SCREENING Optimum 1st trimester screening test is provided by ANOMALY SCAN at 18 - 20 wks a combination of: • Age of the mother 3D / 4D SCAN at 18 - 20 wks • Nuchal Translucency measurement • Nasal Bone (Present / Absent) 3D / 4D SCAN at 28 - 34 wks • Free b-HCG and PAPP-A levels in the mother • Tricuspid Regurgitation (Present / Absent) COLOUR DOPPLER at 30 - 40 wks • Physical abnormality (Present / Absent) Pg: 1 Website: www.vitalradiology.com Ph: 26301184 EXCELLENCE IN IMAGING… Blog: http://soundofbabies.blogspot.com 26301185 ALWAYS…
  • 2. Imaging IMAGING CENTRE Redefined Vol : 4 Iss : 3 The Sound Of Babies… 11 – 14 week USG! NUCHAL TRANSLUCENCY (NT) - NASAL BONE (NB) - The presence of fetal nasal bone is NT is the sonographic appearance of subcutaneous reassuring & is particularly useful for accumulation of fluid behind the fetal neck in first trimester. patients with risks between 1 in 150 & 1 The term translucency is used, irrespective of in 300 who are traditionally classified as whether it is septated or not & whether it is confined screen positive, but with the presence of to the neck or envelopes the whole fetus. the nasal bone confirmed, may be The incidence of chromosomal & other abnormalities sufficiently reassured. is related to the size, rather than the appearance. During the second trimester, the translucency An absent nasal bone will increase usually resolves &, in a few cases, it evolves into dramatically the risk for Trisomy 21, but either nuchal edema or cystic hygromas with or our advice is that such patients are rescanned in one week & action is only without generalized hydrops. taken at that point if there is persistence NT increases with the gestational age, approx of the absence of the nasal bone. 17% per wk. At 11–14 wks the nasal bone is not NT is increased in fetuses with visible by USG in about 60–70% of fetuses with trisomy 21 & in about 2% of Chromosomal & other abnormalities chromosomally normal fetuses. (Trisomies 21, 18 & 13, Triploidy & Turner’s syndrome) . Cardiac defects(septal defects) Pulmonary (diaphragmatic hernia) Renal & abdominal wall defects Certain genetic syndromes & perinatal risks METHOD OF SCREENING SENSITIVITY (%) Maternal age (MA) 30 MA & maternal triple marker at 15–18 weeks 50–70 MA & fetal NT at 11–14 wks 70–80 MA & fetal NT, maternal free b-hCG & PAPP-A at 11–14 wks 85–90 MA & fetal NT & fetal NB at 11–14 wks 90 MA & fetal NT, NB, maternal free b-hCG & PAPP-A at 11–14 wks 95 (For Private Circulation Only) For more information, questions or (NT: Nuchal Translucency, NB: Nasal Bone, b-hCG: human chorionic gonadotropin, Suggestions please call us on 26301184 / 85 PAPP-A: pregnancy-associated plasma protein A) Or email us at newsletter@vitalradiology.com Pg: 2 MULTI SLICE CT SCAN DIGITAL X-RAY PATHOLOGY 24 x 7 MULTI SLICE SONOGRAPHY DIGITAL OPG ECG VITAL MOBILE IMAGING! 3D / 4D SONOGRAPHY 2D ECHO PFT COLOR DOPPLER STRESS TEST HEALTH CHECK UPS Ph: 26301184 / 85