1. Noorahmah Adiany Ansari 110 207 005
Eko Wahyuddin S 110 208 063
Counselor supervisor : dr. A.M.Adam, Sp.KK (K)
Adviser : dr. Sari Handayani P.
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2. Candidiasis is a fungal disease, which is acute or subacute
caused by Candida species usually by the species Candida
albicans, and can affect the mucous membranes, skin, nails,
GI tract, and can also infect the organ in systemic.
The synonim of Candidiasis are Candidosis or Moniliasis
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3. Candidiasis disease found worldwide, can affect all ages, both male
and female. Candidiasis also associated with predisposing factors
Chronic Disease
Contact with
patients with
sexually AGE
transmitted
diseases
endogenous
and Temperature and high
pregnancy, obesity,
Endokrinopati, exogenous humidity, Hygiene of
skin
predisposing
factors
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4. Candida albicans is the yeast in the oval size 2-6 × 3-9 μM
that can produce stem cells, pseudohyphae, and true
hyphae.
Figure 1. Candida in Pottasium hydroxide preparation.
Pseudomycelia in clusters of grape-like yeast cells
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5. Classification of Candidiasis infection based on the
site of predilection which is on mucocutan candidiasis,
systemic candidiasis, cutis candidiasis, and chronic
mucocutaneus candidiasis.
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6. Based on an exposed spot, Conant et al (1971) share as a local
candidosis which can be distinguished clinically:
Candidiasis of mucous membranes (mucocutaneous):
1. Oral candidiasis (thrush)
2. Perleche
3. Vaginalis candidiasis (vulvovaginitis)
4. Balanitis or balanopostitis
5. Chronic mucocutaneous candidiasis
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7. C.Albicans invasion
decreased
immunity into the tissue
predisposing holding the patient's
factors body
Tissue
damage Attachment of
microorganisms in
the host cell tissue
supported by molecular enzymes of
candida albicans
Blastospora develop into C. albicans penetrate
the mucosal epithelial
hyphae and pseudo-hyphae
cells
apparent pressure from the
tissue damage, so the
invasion into the tissue can
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occur.
8. Oral Candidiasis (Thrush).
white looks gray pseudomembrane that covers the
tongue, palate mole, inner cheek, and other oral cavity
surfaces
Figure 2. Oral candidiasis: thrush Extensive cottage cheeselike plaques, colonies of
Candida (pseudomembranous), Patches of erythema between the white plaques
represent erythematous (atrophic) candidiasis.
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9. Perleche
Lesions in the form of fissures or cracks in the skin at
an angle of mouth; lesions underwent maceration, erosion,
wet, and basically erythematous.
Figure 3. Candida perleche with erythema and fissuring at the corners of the
mouth.
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10. Vulvovaginitis.
white patches on erythematous mucosa erosive, ranging from the
cervix to the introitus vagina, and especially the vagina 1/3 bottom. the
lump apart from the mass of the vulva or vagina wall is composed of
necrotic material, epithelial cells, and fungi.
Figure 4. Vulvovaginal candidiasis. Figure 5. Vulvovaginal candidiasis.
White patches appear on the White patches appear on the
erythematous mucosa in the labia major erythematous mucosa in the cervix
and minor 10
11. Balanitis or balanopostitis
white patches on the membrane of the glans penis is often
entirely become erythematous and erosive
Figure 6. candidiasis : balanoposthitis. Figure 7 .Erythema and white plaques
several discrete pustules on the glans seen on the glans penis
penis and in the prepusium. and prepusium
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12. Chronic mucocutaneous candidiasis.
This disease arises because of the lack of leukocyte function or
hormonal systems, usually found in patients with a variety of genetic
deficiency, generally found in children - children.
Figure 7. Mucocutaneous candidiasis of the scalp of patients with chronic. 12
13. 1. Anamnesis and Physical Examination
2. Direct examination.
Mucocutaneous swabs examined with 10% KOH solution
or by Gram staining : yeast cells, blastospora, or pseudo
hyphae.
Figure 8. Candida albicans: KOH preparation: Budding yeast forms and
sausage-like form of pseudo hyphae
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14. 2. Examination of cultures
Material to be examined in order to be planted in
Sabouraud dextrose glucose, can also be affixed to these
antibiotics (chloramphenicol) to prevent bacterial
growth.
Figure 9. Colonies of Candida albicans.
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15. 1. Oral Candidiasis (Thrush)
Leukoplakia is a clinical term
that refers to an oral mucosal
white patch that will not be
contagious.
Figure 10. Hairy leukoplakia appears as a broader and plaques on
the lateral folds of the tongue
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16. 2. Trichomonas vaginalis
Vulvovaginitis with vaginal secretions
There is a yellow-green
secretions, smells bad and
frothy, vaginal walls are reddish, and
there are strawberry appereance of the
cervix.
Figure 11. This patient presented with a "strawberry cervix" due to
a Trichomonas vaginalis infection, or trichomoniasis. The term
"strawberry cervix" is used to describe the appearance of the
cervix . The cervical mucosa reveals punctate hemorrhages along
with accompanying vesicles or papules. 16
17. 2. Lichen Planus
lichen planus occurs mainly on
the buccal mucosa, often
bilateral, and sometimes on the
tongue dorsal or lateral.
Figure 12. Oral Lichen planus
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18. 1. Avoid or eliminate the predisposing factors.
2. Topical
3. Systemic
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19. Leukoplakia patients can be a squamous carcinoma,
although rarely.
Patients with AIDS oral candidiasis, chronic
mucocutaneous candidiasis, can be an esophageal candidiasis.
Candidiasis Vulvovaginalis or who have chronic
Candidiasi Vulvovaginalis can lead to chronic dyspareunia to
disrupt the marital relationship.
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20. Prognosis of mucocutaneous candidiasis is
generally good and depends on the severity of
the predisposing factors.
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