Our Aim was to bridge the gap between us and other departments through highlighting who the ClinChem dept is, what it does and how it does it. It shines light on some of our latest achievements during 2011 in the areas of Teaching & Training, Research & Laboratory Services.

1. 1
ABOUT US
Dr. Nelly Abulata
Lecturer of Clinical Pathology
MD, MBA, DTQM
Annual Conference Kasr Al-Ainy Faculty of Medicine – Cairo Univ
22nd April, 2012

2. I. Faculty & staff
II. Education
III. Research
IV. Patient care

3. Faculty & Staff

4. CHAIR OF THE CLINICAL & CHEMICAL
PATHOLOGY DEPARTMENT
Prof. Safaa Al-Karaksy

5. Mission
“Is to provide excellence in
Laboratory services, Teaching,
Training, and Research activities”.

6. Organizational Changes
6
1. Plans, organization charts and job descriptions
2. Operational issues & Projects were monitored, analyzed, evaluated
and reported.
3. Website, Data base and Annual progress reports for the Department
4. Deputies to the Chair:
 Scientific Research
 Teaching & Training
 Examination
5. Executive Committees:
 Laboratory Executive Committee
 Blood Bank Executive Committee
 Conference Organizing Committee
 2 Quality Assurance Committee; 1 Lab service, 1 Education
 Scientific Research Committee

7. Organizational Chart
7
Chairman of the Board of the
Haematology Clinical & Chemical Pathology
Department
Immunology
Microbiology Routine
Cytogenetics Hormones
Molecular Head of the Head of the
Electrolytes
Clinical Chemical
Pathology Pathology Proteins
Abou Maternity ER
Manial Japanese Internal King Sharm Hospital
Lab
Elrish French 4th Floor Psychiatry Hospital
Labs Medicine ElSheikh
Lab
Lab Lab. Lab Fahd Lab. Hospital
Lab. Lab. Lab
Oncology & Nuclear
Blood Bank Medicine Lab

8. Organogram (2011-2012)
8
Main Lab at Manial Hospital
Laboratory Head of Lab. Lab Director Head of Head of Head of Head of the Head of
(Technical) (Administrative) Hematology Immunology Genetics unit Molecular Unit Microbiology
Unit Unit Unit
Manial Prof. Dr. Prof. Dr. Mona Prof. Dr. Prof. Dr. Prof. Dr. Hala Prof. Dr. Mona A. Prof. Dr.
Clinical Mervat Al- Salah Naguib Mervat Al- Farawella Salah Nada Nawar
Pathology Ansary Zoheir Ansary
Lab.
Laboratory Head of Lab. Lab Director Head of Head of Head of Head of
(Technical) (Administrative) Trace Chemistry Proteins Unit Hormones Unit
Elements Routine Unit
Unit
Manial Chemical Prof. Dr. Fatma Prof. Dr. Prof. Dr. Prof. Dr. Prof. Dr. Sahar Prof. Dr. Nadida
Pathology Lab. El-Mougy Badawy Al- Badawy Al- Lamia Abdel-Atty Gohar
Khouly Khouly Mansour

9. Laboratory Head of Lab. Lab Director Head of Head of Head of Head of Chemical
(Technical) (Administrative) Hematology Immunology Microbiology Pathology
Internal Medicine Prof. Dr. Dr. Magda Negm Prof. Dr. Sahar Dr. Mohamed A. Prof. Dr. Nahla
Hospital Lab. Sahar Kamal Kamal Abdul‫م‬ah Fawzy
Japanese Hospital Lab.
9 Prof. Dr. A. Prof. Doha Prof. Dr. Dr. Rabab El- A.Prof. Dr. Prof. Dr. Ola
Hanaa Abdel Hamid Hanaa Hawary Mona Mohie ElSissy
Arnaout Arnaout El-Din
Abou-Elrish Mounira Prof. Dr. Azza Prof. Dr. Hala Prof. Dr. Hala A. Prof. Dr. Dr. Hanan Madany
Hospital Lab. Abou ElEnain Gabr Gabr Maha Gaafar
Specialized Hospital Lab. Prof. Dr. Dr. Sheriene Prof. Dr. A. Prof. Aya Prof. Dr. Walaa Prof. Dr. Iman
(4th floor) Taysir Eyada Abdel-Kader Hanaa Nassef Gad Mandour
Arnaout
French Hospital Lab. Prof. Dr. Laila Dr. Hanan Prof. Dr. Prof. Dr. Nancy Prof. Dr. Amani Prof. Dr. Hazem
Hegazy Ibrahim Nabil El- ElGuindy ElKholy Abou Youssef
Danasoury
King Fahd Hospital Lab. A. Prof. Manal Kamal
Psychiatric Hospital Lab. Prof. Dr. Badawy Al-Khouly
New ER Hospital Lab Prof. Dr. Badawy Al-Khouly
Maternity Hospital Lab. Prof. Dr. Assistant Prof. TBD TBD Prof. Dr. Iman
Iman Aya Nassef Mandour
Mandour
Sharm ElSheikh Int. Hosp. Assistant Prof. Mohamed Shehata
Blood Bank Prof. Dr. Dr. Sahar Azab
Mervat Al-
Ansary

10. Manpower of 1000
44
24 Faculty staff
Specialists
Residents
250
450
393
400
350
318
300
250
200
150 141
100 89
62
50
0
Doctors Technologists & Nurses Administration Cleaners
Technicians

11. Role of the Department
Patient care
(Laboratory
Service)
Education
(Teaching Research
& Training)

12. Education

13. Teaching & Training Programs
Undergraduates:
 The Department provides teaching to the 6th year students
(Clinical & Chemical Pathology curriculum)
 Recently we have delivered Summer training to Undergraduates
Postgraduates:
 The Department is committed to providing strong and balanced teaching and training
programs mainly to Postgraduate students, principally in the Master and Doctorate
degrees in Clinical and Chemical Pathology tailored to each student subspecialty:
 Hematology
 Clinical Immunology
 Clinical Microbiology
 Clinical Chemistry
 The Department is also partly involved in the teaching & training of Postgraduate students
of other Departments enrolled in Master, Diplomas & Doctorate degrees.
 Egyptian Fellowship Board training

14. Seminars & Conferences
Weekly Seminars:
 Immunology: Every Sunday of the week
 Hematology: Every Monday of the week
 Chemical Pathology: Every Monday of the
week
 Microbiology: Every Tuesday of the week
Yearly:
 Scientific ClinChem Conferences
 1st CLINCHEM 2010 Conference"
Molecular Biology: Into the future" 31st of
March -2nd of April
 2nd CLINCHEM 2010 Conference
"Transfusion Medicine & Quality updates:
Revolution not evolution" 24th of October,
2010
 3rd CLINCHEM 2011 “Genetics and Tissue
Engineering”, 3rd - 5th of April, 2011.
 CLINCHEM 2012 Course “Regenerative Medicine” in collaboration with the University
of Toronto starting from September 2012 to May 2013 (organization in process)

15.  In collaboration with the ESLM, the
ClinChem Kasr Al-Ainy Team organized
the ESLM 2012 Conference 18-20
April 2012 at CICC
Workshops (currently running at our Labs):
 Microbiology (17/4)
 Parasitology (21/4)
 Stem cells (22/4- 24/4)
 DNA sequencing (22/4- 24/4)

16. 2011 Training workshops
 “Screening metabolic disorders by Tandem Mass Spectrometry” Workshops
Organized via a collaboration between the Chemical Pathology team (Prof. Dr.
Fayza A Hassan Prof. Dr. Fatma El-Mougy Prof. Dr. Sahar Abdel-Atty Prof. Dr. Iman
Mandour A. Prof. Dr. Marian Morgan Dr. Dina Mehaney Dr. Mohammed A. Monem)
and the Pediatric Endocrinology team at Pediatric Hospital.
 2 workshops Infection Control Team (Lead Prof. Amani Al-Kholy & her team A.
Prof. Mervat Gaber Al-Anainy, A.Prof. Mona Mohieddin Abdel Halim, Dr. Mariam
Adel, A. Lecturer Mai Sherief) in collaboration with:
 NAMRU-3 on: Practical Approach to prevention of Healthcare associated
infections in Cairo University Hospitals
 NAMRU-3, USAID, CDC and Cornell University on: Advanced training on
Infection prevention and control

17. Research

18. According to our Research plan
Key research subjects
1. HCV
2. Stem Cell Research
3. Neurodegenerative diseases
4. Infection prevention and control
5. Molecular basis of Hematological disorders
6. Juvenile Diabetes Mellitus.

19. 2011 Research Awards
1. Prof Heba Abdel Razik has won:
 The National Egyptian Promotional Award
 The Cairo University Encouragement Award
2. Prof. Dr. Hala Gabr won the “University Award for
the Highest impact factor”

20. 2011 Research Projects & Grants
1. Several projects received funding from the Faculty
2. STDF grant:
1. "Stem Cell Therapy in End stage liver cell failure". (Principle investigator: Prof.
Dr. Hala Gabr)
2. "Phase I-II clinical trial autologous dendtritic cell vaccine in patient with acute
myeloid leukemia in remission. (Principle investigator: Prof. Dr. Mervat Al-
Ansary)
3. Cairo University grant:
1. "Isolation and identification of Limbal Stem Cells“ (Co-investigator Prof. Dr.
Hala Gabr)
2. "Study of the pluripotent stem cell potential of Peripheral blood mononuclear
cells “ (Principal Investigator Prof. Dr. Mervat Al-Ansary)
4. Joint projects:
1. NAMRU-3 project “Study of the sentinel surveillance for severe respiratory
illness (SARI) (Project Manager: Prof. Dr Amani El Kholy)
2. NAMRU-3, USAID & Cornell University National project: “ Quality
improvement and patient safety (Project Coordinator: Prof. Dr Amani El Kholy)

21. International Publications in 2011
>20
Paper Title Research Team Journal Name Impact
factor
FcgRIIa and FcgRIIIa genetic Tayseer K. Eyada, Hala M. Farawela, Blood
polymorphisms in a group of Mervat M. Khorshied, Iman A. Shaheen, Coagulation 1.4
pediatric immune Neama M. Selim and Iman A.S. Khalifa and Fibrinolysis
thrombocytopenic purpura in
Egypt
Association of C46T genetic Naguib M. Zoheir, Mona S. Hamdy, Comp Clin
polymorphism of coagulation Mervat M. Khorshied, Nelly N. Abulata, Pathol 0.3
factor XII with deep venous Mehry El Sobky, Amr M. Saleh, Hussein
thrombosis: a cohort study on M. Khairy
Egyptian patients
Quantitative Assessment of Wilms Hoda Ali Sadek, Wafaa Hassan El- Journal of
Tumor 1 (WT1) Gene Transcripts in Metnawey, Iman Abdel-Mohsen Investigative 1.598
Egyptian Acute Lymphoblastic Shaheen, Mervat Mamdouh Korshied, Medicine
Leukemia Patients Azza Sobieh Mohamed

22. Paper Title Research Team Journal Name Impact
factor
Mannose binding lectin (MBL2) gene Menat Allah Kamal El Deen, Comp Clin 0.3
polymorphism in sickle cell anaemia: an Mervat M. Khorshied, Zeinab A. Pathol
Egyptian study El Sadani, Yasmine M. Amrousy,
Nermeen M. Galal
CD200 Expression in B-Cell Chronic Nermeen Ahmed El Desoukey, Journal of 1.536
Lymphoproliferative Disorders Reham Abd Aleem Afify, Dalia Investigative
Gamil Amin, Rasha Faragaly Medicine
Mohammed,
Clinical and laboratory evaluation of Amer ME, El-Sayed SZ, El-Kheir Eur J 1.598
patients with end-stage liver cell failure WA, Gabr H, Gomaa AA, El- Gastroenterol
injected with bone marrow-derived Noomani N Hegazy M Hepatol
hepatocyte-like cells
Limb salvage using intramuscular injection Gabr H, Hedayet A Imam U, Exp Clin 0.6
of unfractionated autologous bone marrow Nasser M Transplant
mononuclear cells in critical limb ischemia:
a prospective pilot clinical trial

23. Paper Title Research Team Journal Name Impact
factor
Effect of stem cell therapy on Zaghloul S, Zickri M,Abd El Aziz Int J Stem Cells
amiodarone induced interstitial D, Mabrouk D, Gabr H
lung fibrosis in albino rats
Autologous Mesenchymal Stem Gabr, Hala; Ghannam, American Journal
Cell Therapy for Spinal Cord Osama; Awad, Mohamed of Neuroprotection
Injury: Long Term Safety and Reda; von Wild, Klaus; El-Kheir, and
Clinical Efficacy Wael Abo; Ewes, Ibrahim Neuroregeneration
Viability and neural Aly H, Mohsen I,Badrawi N, Journal of 2.003
differentiation of mesenchymal Gabr H, Ali Z, Akmal D Perinatology
stem cells derived from umbilical
cord following perinatal asphyxia
Tumor necrosis factor Azza Ibrahima, Hala Abdel Leuk Res 2.33
alpha−308 and Lymphotoxin Rahmana, Mervat
alpha+252 genetic Khorshieda, Rania Samia,
polymorphisms and the Nelly Nasra, Ola Khorshid
susceptibility to non-Hodgkin

24. Paper Title Research Team Journal Impact factor
Name
Do Serum Angiopoietin-1, Angiopoietin-2, Manal Kamal and Journal of 1.536
and Their Receptor Tie-2 and 4G/5G Waleed El-Khayat Investigative
Variant of Medicine,
PAI-1 Gene Have a Role in the Pathogenesis
of Preeclampsia?
Phase II Trial: Undifferentiated Versus Mervat El-Ansary, Iman Stem Cell 3.76
Differentiated Autologous Mesenchymal Stem Abdel-Aziz, Sherif Rev and Rep
Cells Transplantation in Egyptian Patients with Mogawer, Samah Abdel-
HCV Induced Liver Cirrhosis Hamid, Olfat Hammam,
Salwa Teaema, Marwa
Wahdan

25. Paper Title Research Team Journal Impact
Name factor
Flow cytometric detection of Manal W. El-Masry, Comp Clin 0.3
leukemic stem cells (LSCs) in Mervat M. Khorshied Pathol
Egyptian pediatric B-acute Iman A. Shaheen, Nelly
lymphoblastic leukemia N. Abulata & Tarek A.
Hashem
Mesenchymal stem cells expanded AbdelRazik H., Eu J Immu 4.942
in human platelet lysate display a Spaggiari GM,
decreased inhibitory capacity on T Chiossone L., Moretta L.
and NK proliferation and function
Direct contact of umbilical cord Lupu M, Khalil M, J Cell Mol 4.608
blood endothelial progenitors with Iorache F, Andrei E, Med
living cardiac tissue is a Pfannkuche K,
requirement for vascular tube-like Spitkovsky D,
structures formation Baumgarrtner S, Rubach
M, Abdel Razik H

26. Paper Title Research Team Journal Impact
Name factor
Antimicrobial Resistance in Pathogens Tamer Saied, Amany El Am J Infect 3.077
causing Nosocomial Bloodstream kholy, Soad F. Hafez, Hadia control.
Infections in University Hospitals Basim, Momtaz O. Wasfy,
Waleed El-Shoubary,
Ahmed Samir, Guillermo
Pimentel and Maha Talaat
Prospective study of healthcare- Amani El Kholy, Mariam Arab Society 0.697
associated bloodstream infections in Younan. for
pediatric intensive care units in Cairo Laboratory
University Hospitals Medicine.
Assessment of the role of Manal Kamal, Mona M Annals Of
paraoxonase gene polymorphism Fathy, Eman Taher, Manal Saudi
(Q192R) and paraoxonase activity Hasan, May Tolba Medicine.
in the susceptibility to atherosclerosis
among lead-exposed workers.

27. This is the First Edition of the Eastern Mediterranean
Acute Respiratory Infection Surveillance (EMARIS)
27
Network Bulletin!
Participants from our Dept.
 Lead by Prof. Amani ElKholy
 Infection control team
Partnership between
 CDC's Egypt Global Disease Detection and Response Center (GDDRC)
 U.S. Navy
Medical Research Unit No. 3 (NAMRU-3),
 the WHO Office of the Eastern
Mediterranean (EMRO
With the support of the
 World Health Organization (WHO),
 U.S. Centers for Disease Control Prevention (CDC),
 U.S. Department of State, and the U.S. Department of
Defense.

28. Patient care

29. Laboratory services
 Our Laboratories provide an extensive menu of routine &
specialized laboratory tests to the patients who seek care at Kasr
Al-Ainy Hospitals.
 Lab Specialties
 Hematology Laboratory
 Clinical Immunology & Molecular Diagnostics
 Clinical Microbiology
 Clinical Chemistry
 Working Hours:
 8am-2pm at the Main Labs at the Hospitals
 2pm-8am through the Emergency Labs
 Lab tests we provide
(www.clinchemcairo.org)

30. 2011 Annual Productivity
30
4.5million tests
6,000,000
(318)
4,598,604
5,000,000
Total no. of tests & Doctors
4,000,000
3,000,000
(142)
1,888,911
2,000,000
(65)
1,058,813
(16)
1,000,000 595,114 (24)
550,338 (30)
363,137 (24) (2)
170,949 142,291
0
Total Manial French Japanese Internal Abou ElRish 4th floor King Fahd
Medicine
Laboratory

31. Kasr Al- Ainy lab in the 1940’s

32. Hematology Laboratory
Cell Counters Unit Coagulation Unit

33. Hematology (Manial Main Lab)

34. Immunology Laboratory
Axym Unit
ELISA unit

35. Cytogenetics Laboratory
Flowcytometry unit
Karyotyping Unit

36. Molecular Diagnostics Laboratory
PCR unit

37. Microbiology Laboratory
Verification area Working area

38. Chemistry Laboratory
Chemistry routine Unit Trace elements Unit
Hormones Unit

39. Contact us
39
clinchem@kasralainy.edu.eg
www.clinchemcairo.org