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CHOLERA
By
Dr. ANUGOM Emeka.
1. WHAT IS CHOLERA?
•

An acute diarrhoeal disease that can kill within hours if untreated in both children and adults.

•

There are 3-5 million cases every year, with 100,000 to 120, 000 deaths from cholera every year. Common in Asia and Africa

•

Incubation period is from 6 hours to 5 days.

•

It’s caused by bacteria Vibrio cholerae, with two serotypes O1 (mainly) and O139 having the potential of causing outbreaks

2
2. HOW IS CHOLERA SPREAD?
•

Poor Sanitation

•

Drinking Contaminated Water

•

Eating Contaminated Food

•

COMMON SOURCES

•

- Raw or poorly cooked seafood

•

- Raw fruit and Vegetables

•

- Other foods contaminated during preparation and
storage.

•

Main source is bacteria in faeces of infected person.

•

Poor sewage and water treatment.

•

Over populated areas have highest risk.
3
3. THE SITUATION IN NIGERIA
•

Nigeria reported Cholera epidemics in 2010 and 2011, with an estimated 2000 deaths during
this period.

•

This was mainly due to poor sanitation and over population, scarcity of clean drinking water

•

It is usually prevalent in the rainy seasons between April to October.

•

Currently in 2013, there have been over 1600 reported cases, with an estimated 86 deaths from
cholera.

•

Zamfara and Nasarawa states in Nigeria are the worst hit states.

•

However cases have also been reported in Kebbi, Sokoto, Plateau, Lagos, Ogun and Oyo state

4
4. THE SITUATION IN NIGERIA

5
5. SYMPTOMS OF CHOLERA
•

Mostly mild diarrhoea or no symptoms at all.

•

However in 5-10% of patients, very severe
watery diarrhoea (rice-water stool) and
vomiting may occur

•

If untreated, this leads to:

•

Severe dehydration from fluid loss and

•

Death within hours.

6
6. PREVENTION OF CHOLERA
•

Simple Rule:

•

Boil it – Cook it – Peel it OR Forget it.

•

1. Drink only properly treated water

•

N:B Beverages (tea/coffee), Wine, Beer, Carbonated water and Soft
drinks, Bottled/packaged fruit juices are usually safe to drink.

•

2. Avoid Ice unless you’re sure it’s from safe water source.

•

3. Eat food that has been well cooked and served still hot.

•

(food at room temperature for several hours and served without
reheating is a source of infection)

7
7. PREVENTION OF CHOLERA
•

4. Avoid raw seafood and other raw foods. (Fruits and
Vegetables properly peeled and shelled by you is an
exception)

•

5. Boil unpasteurized milk before drinking it.

•

6. If in doubt of reliability of source of ice cream, avoid it .

•

7. Ensure meals bought from street vendors are thoroughly
cooked in your presence and do not contain uncooked foods.

•

8. Proper hand washing , especially before food preparation,
during meals, work and after use of sanitary facilities

8
8. TREATMENT FOR CHOLERA
•

1. SEEK MEDICAL HELP URGENTLY

•

2. REHYDRATION:

•

MOST important, especially for diarrhoea and
vomiting, to replace water and salt lost early.

•

A. Use oral rehydration salts, if unavailable take water
and other non-sweetened fluids e.g. soup.

•

B. Give intravenous fluid infusion in the severely
dehydrated.

9
9. TREATMENT OPTIONS FOR CHOLERA
•

3. ANTIBIOTICS:

•

May be used in some cases to shorten illness
duration.

•

However not recommended for MASS treatment as it
doesn’t limit the spread

•

ANTIDIAARHOEAL DRUGS:

•

Loperamide (Imodium) use is NOT recommended and
should NOT be given.

10
10. IMMUNIZATION FOR CHOLERA
•

VACCINATION:

•

INJECTABLE CHOLERA VACCINE:

•

Formerly used and gives incomplete, unreliable protection for
short period. With adverse effects and thus no longer
recommended.

•

ORAL CHOLERA VACCINE:

•

There are two types that give good protection for up to 3years.

•

But doesn’t give 100% protection. Hygiene and sanitary
precautions should also be applied.

•

Given in 2 doses for those above 6yrs old and 3 doses for those
2-6yrs old, 7days to 6 weeks apart.

11
11. IMMUNIZATION FOR CHOLERA
•

They are both whole-cell killed vaccines, licensed for use in over 60
countries by WHO.

•

No meal should be taken 1 hour before and after taking it to ensure
gut absorption.

•

No country requires proof of this vaccination.

•

SHANCHOL

•

This is gives long-term protection against V cholerae O1 and O139 in
children under 5years.

•

DUKORAL

•

This has recombinant B-sub unit, with short term protection 85-90%
against V. cholerae O1 in all age groups 4-6mths of immunization

•

Given in 150ml of water

•

Also useful in diarrhoea caused by Enterotoxigenic E.Coli (ETEC)
12
12. REFERENCES
•

http://www.who.int/mediacentre/factsheets/fs107/en/

•

http://www.who.int/topics/cholera/faq/en/

•

http://www.patient.co.uk/health/cholera-immunisation

•

https://www.internationalsos.com/en/country-guides.htm

•

https://www.internationalsos.com/demo/CountryGuides/DiseasesPrevention.cfm?Img=Dp&Pg=Diseases%20Prevention

•

http://www.niaid.nih.gov/topics/cholera/Documents/CholeraFactSheet.pdf

•

http://news.yahoo.com/cholera-kills-nine-100-hospitalised-nigeria-195406146.html

•

http://www.npr.org/blogs/health/2010/10/29/130923065/tracking-the-origins-of-haiti-s-cholera-strain

•

http://liveshots.blogs.foxnews.com/2011/01/10/haiti-one-year-later-the-cholera-crisis/

•

http://www.cdc.gov/cholera/

•

http://minustahphoto.blogspot.com/2010/11/cholera.html

•

http://intrd187-f11-grosovsky.wikispaces.umb.edu/Cholera

•

http://www.bbc.co.uk/news/world-africa-11093831

•

http://telegraphng.com/2013/10/cholera-outbreak-kills-47-zamfara/

•

http://evatese.wordpress.com/

•

http://www.bbc.co.uk/blogs/africahaveyoursay/2010/08/what-do-you-know-about-cholera-1.shtml

•

http://edition.cnn.com/2010/WORLD/africa/10/26/nigeria.cholera/

•

http://scannewsnigeria.com/breaking-news/cholera-kills-50-in-northern-nigeria/

•

http://www.nigeriahealthwatch.com/2010/09/nigeria-at-50-cholera-outbreak-and.html

•

http://www.un.org/apps/news/story.asp?NewsID=39145&Cr=cholera&Cr1

•

http://www.rayur.com/cholera-causes-symptoms-and-treatment.html

•

http://www.msf.org.au/from-the-field/field-news/field-news/article/cameroon-chad-niger-nigeria-medecins-sans-frontieres-intervenes-in-several-cholera-outbreaks.html

•

http://newshopper.sulekha.com/nigeria-cholera_photo_1502991.htm

•

http://www.haiti.mphise.info/health-education?page=1

13
QUESTIONS

14

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