Louisville CyberKnife is a radiosurgery service located at the James Graham Brown Cancer Center in Louisville, Kentucky. It uses the CyberKnife system to precisely deliver high doses of radiation to tumors using a robotic arm. Treatments are non-invasive, painless, and take 30-90 minutes to complete over 3-5 sessions. The center is part of a national network and works with experienced physicians to provide exceptional care for cancer patients.

1. Louisville
CyberKnife
is
a
service
of
the
James
Graham
Brown
Cancer
Center,
home
of
the
first
na<onally
accredited
radia<on
oncology
program
in
Louisville.
529 S. Jackson St. Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com

2. What is CyberKnife?
CyberKnife®
treats
pa0ents
with
a
procedure
called
stereotac(c
radiosurgery.
Stereotac0c
radiosurgery
is
a
noninvasive
method
of
trea0ng
tumors
with
high-­‐dose
radia0on
precisely
aimed
from
different
angles.
How
does
CyberKnife
work?
CyberKnife
does
not
require
surgery
and
there
is
no
cu7ng
or
anesthesia
required.
CyberKnife
is
comprised
of
a
compact
linear
accelerator
—
a
machine
that
generates
a
radia0on
beam
—
aCached
to
a
highly
maneuverable
robo0c
arm.
• During
treatment,
the
machine’s
robo0c
arm
moves
around
you,
aiming
and
firing
targeted
radia0on
beams
from
numerous
angles.
• The
imaging
and
tracking
system
con0nually
updates
the
tumor
loca0on
throughout
the
treatment
procedure,
compensa0ng
for
pa0ent
movements
like
breathing.
• Treatment
sessions
typically
last
30
-­‐
90
minutes.
529 S. Jackson St. Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com

3. 529 S. Jackson St. Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com

4. Why Choose CyberKnife?
CyberKnife
Conven(onal
Linac
Proton
Therapy
Stereotac(c
Radia(on
Stereotac(c
Radiosurgery
Therapy
Radiosurgery
Daily
dose
5.0-­‐2.0
1.8-­‐3.0
5.0-­‐20
1.8-­‐2.0
Gy
per
frac0on
Gy
per
frac0on
Gy
per
frac0on
Gy
per
frac0on
Number
of
3-­‐5
days
6-­‐7
weeks
3-­‐5
days
6-­‐7
weeks
treatments
Accuracy
((ssue
20-­‐30
20-­‐30
1.5
millimeters
1-­‐5
millimeters
margin)
millimeters
millimeters
Number
of
radia(on
beams
100-­‐200+
beams
2-­‐7
beams
5-­‐15
beams
2-­‐3
beams
Con(nuous
correc(on
for
breathing
and
YES
NO
NO
NO
movement
• Treats
pa0ents
in
as
few
as
five
visits
• Reaches
most
tumors
from
virtually
unlimited
• Pain-­‐free
and
requires
no
anesthesia
direc0ons
with
robo0c
mobility
• Minimal
side
effects
• Minimizes
radia0on
exposure
to
healthy
0ssue
• Outpa0ent
procedure
surrounding
a
tumor
site
• Constantly
corrects
for
tumor
or
pa0ent
movement
• Lesions
previously
treated
with
maximum
allowed
throughout
procedures
radia0on
doses
may
be
treated
529 S. Jackson St. Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com

5. What does CyberKnife treat?
• Arteriovenous
malforma0on
• Bone
metastases
• Brain
tumors
• Acous0c
neuroma
• Brain
metastases
• Gliomas
• Astrocytoma
• Glioblastoma
mul0forme
• Glioma
• oligodendroglioma
• Meningioma
• Pituitary
adenoma
• Kidney
tumors
• Liver
tumors
• Lung
tumors
• Ocular/orbital
tumors
• Prostate
cancer
• Pancrea0c
cancer
• Spinal
tumors
• Trigeminal
neuralgia
529 S. Jackson St. Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com

6. What is the treatment process?
Consulta0on
Meet
with
the
Create
an
individualized
Appointment
CyberKnife
team
treatment
plan
Poten0al
Tissue
Markers
Pretreatment
CT
Scan
MRI
Lab
Studies
(extracranial
tumors
or
lesions)
Procedures*
The
advanced
tracking
CyberKnife’s
system
takes
X-­‐ray
CyberKnife
Technicians
help
you
onto
the
robo0c
arm
moves
around
you
firing
images
to
ensure
the
If
needed,
you
return
for
up
to
4
Treatment
treatment
table
targeted
radia0on
beams
radia0on
beam
remains
locked
on
the
more
treatments.
tumor
Follow-­‐up
imaging
and
physical
Follow-­‐up
consulta0on
to
monitor
tumor’s
progress
*The
procedures
required
as
part
of
your
individualized
treatment
plan,
and
the
order
in
which
they
will
occur,
will
be
explained
during
your
consulta0on
visit.
529 S. Jackson St. Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com

7. Our Center
Louisville
CyberKnife
is
part
of
the
renowned
James
Graham
Brown
Cancer
Center,
home
of
the
first
na0onally
accredited
radia0on
oncology
program
in
Louisville.
Our
center
brings
together
experienced
physicians
and
the
latest
medical
advances
to
provide
pa0ents
with
excep0onal
care.
Our
center
u0lizes
the
CyberKnife®
9.6
system,
which
features
a
device
that
controls
the
width
of
the
machine’s
radia0on
beam,
allowing
clinicians
to
vary
the
beam
size
and
treat
a
larger
variety
of
tumors
throughout
the
body.
Medical
Director:
Shiao
Woo,
M.D.
M.B.B.S.
F.A.C.R.
Radia(on
Oncologist:
Moataz
El-­‐Ghamry,
M.D.
CyberKnife
Nurse
Navigator:
Anna
Murphy,
R.N.
Connect
with
us
529 S. Jackson St. Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com

8. The US Radiosurgery Network
In
partnership
with
the
James
Graham
Brown
Cancer
Center,
Louisville
CyberKnife
is
a
US
Radiosurgery
facility.
Based
in
Nashville,
Tennessee,
US
Radiosurgery
is
a
division
of
Alliance
Oncology
and
partners
with
hospitals
and
physician
groups
around
the
U.S.
to
develop
and
operate
full-­‐body
radiosurgical
centers.
Collec(vely,
the
US
Radiosurgery
network
of
centers
has
treated
thousands
of
pa(ents
since
the
opening
of
the
company’s
first
center
in
2003.
The
group
of
facili0es
is
ac0vely
engaged
in
research,
with
physicians
regularly
presen0ng
papers
and
authoring
ar0cles
related
to
the
efficacy
of
CyberKnife
treatment
for
various
types
of
tumors
and
lesions.
Tumors
of
the
lung,
brain
and
prostate,
as
well
as
certain
func0onal
disorders
such
as
trigeminal
neuralgia,
have
become
key
treatment
areas
throughout
the
network
of
centers.
529 S. Jackson St. Louisville, KY 40202 (502) 217-8200 www.louisvilleck.com