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Volume 2, Issue 1                                                                                                     31 January 2013




      MPDA e-Newsletter
                     H    .     L   E    E    M   O   F   F   I   T   T   C   A   N   C   E   R   C   E    N    T   E   R


       S A V E T H E
         D A T E S                           S c i e n t i f i c              s u b m i s s i o n                   s t u d i o
                                                                                 ( S 3 )
  •      March 15, 2013
         Postdoc Town Hall              With all of the pressures in      editors and scientific writ-         grant to the review board,
         with Dr. Sellers               science to publish quality        ers).                                and distribute reviewer
  •      April 23, 2013                 work and to successfully                                               comments back to the sub-
         Career Workshop                acquire funding, don’t you        How does it work?                    mitter. The S3 board will
         and Interview Prepa-           wish that you had some-           An S3 request form with the          meet to review submissions
         ration Seminar
                                        thing that could boost your       following information: an            every 3rd Thursday of the
                                        chances while also provid-        abstract of the submission,          month. Individuals must
                                        ing you with the necessary        proposed journal of submis-          request an S3 review no
                                        developmental tools to im-        sion, and a proposed panel           less than two months be-
  I N S I D E T H I S
       I S S U E :
                                        prove your writing?               of reviewers (first and se-          fore the proposed submis-
                                                                          cond choice of Moffitt facul-        sion to allow substantial
Postdoc Spotlight               2       Where can I find something        ty) of the submitter’s choos-        time for review and distribu-
                                        like this?                        ing will be submitted to the         tion of comments back to
Town Hall Meeting               2
                                        The Moffitt Postdoctoral          S3 portal on the MPDA web-           the submitter.
Career Workshop;                        Association would like to         site. Potential reviewers will
Interview Preparation           3
Seminar                                 present S3 (Scientific Sub-       be asked to respond within           This sounds great. When
                                        mission Studio), an internal      a week of inquiry; upon              will it start?
Internship Opportunity          3       review board designed as a        acceptance, the submitter            The MPDA is currently in
                                        tool for junior scientists to     will provide a publication-          the planning process for S3
OSR Q&A Session                 4
                                        improve upon the quality of       ready manuscript to the              and are in need of eager
Scientific Communica-
                                4
                                        manuscripts and grant pro-        MPDA who will distribute             scientists ready to submit
tion Seminar Series
                                        posal submissions. With S3,       the work to the review               their work and senior Mof-
Research Colloquium             5       junior scientists at Moffitt      board members. Submit-               fitt members willing to pro-
                                        (including: postdoctoral          ters must have the permis-           vide their expertise and a
Career & Skill Develop-
                                5       fellows, graduate students,       sion and signature of ap-            little time to help review
ment Resource Library
                                        and research assistants)          proval from his or her pri-          submitted work. With a little
Featured Publications           6       can receive feedback on           mary mentor on the re-               help from our wonderful
                                        publication-ready manu-           quest. The MPDA will pro-            Moffitt team, we are hoping
MPDA Seminar Series             6
                                        scripts from a pre-approved       vide the request form, facili-       to launch this new service
MPDA Council, New                       committee comprised of            tate the assembling of the           this upcoming fall.
                                7
Leadership
                                        members of our Moffitt            review board members,                                      —L. Cook
New Postdocs                    7       team (experienced journal         distribute the manuscript or
V o l u m e   2 ,   I s s u e   1                                                                                              P a g e   2




                                    P o s t d o c              s p o t l i g h t
 This quarter’s Postdoc Spotlight fea-       and packed schedule, I was very grate-     of research. I am thankful for Dr. Yu’s
 tures Dr. Kelley M.K. Haarberg. Cur-        ful to have a chance to sit down with      support in my work and appreciate his
 rently, Kelley trains as a 3rd year re-     Kelley for a few minutes and ask her a     backing and mentorship.
 search fellow in the laboratory of a        few questions about her experiences
                                                                                        Q: What is your greatest daily chal-
 well-regarded Moffitt Cancer Center         here at Moffitt.
                                                                                        lenge?
 investigator, Dr. Yu. Dr. Yu’s laboratory
                                             Q: What are your research goals and
 is actively involved in ground-breaking                                                My greatest daily challenge is making
                                             tell us a bit about your project?
 research in the field of graft-versus-                                                 sure my experiments flow and that I
 host disease (GVHD). Dr. Haarberg has       We have just wrapped up a line of          have planned them correctly and I
 more than eight years of basic science      investigations involving genetic and       execute them with efficacy and dili-
 research experience in cellular and         pharmacologic PKCα and PKCθ inhibi-        gence. In my field of work, remaining
 molecular biology, microbiology and         tion to dampen detrimental alloreac-       focused is the key to success. It is very
 immunology and more                                               tivity in the con-   easy to get side-tracked as we get very
 than five years of clini-                                         text of acute        passionate about what we do.
 cal/patient care experi-                                          GVHD. I am most      Q: How do you like to spend your “Me
 ence. Her project cur-                                            recently opening     time”?
 rently is to develop                                              a new line of in-
                                                                   vestigation to       Well, I have been blessed with many
 genetic and pharmaco-
                                                                   explore the meta-    things in my life so far but, the most
 logic T-cell manipula-
                                                                   bolic profiles of    important thing in my life is my daugh-
 tion strategies to pre-
                                                                   alloreactive T       ter. I love spending time with her and
 vent acute GVHD. In
                                                                   cells and how T      my family. What completes me and
 addition to everyday
                                                                   cell metabolism      gives me the resolve to do what I do is
 laborious post-doctoral
                                                                   contributes to and   to maintain a balanced personal and
 research obligations,
                                                                   could be exploited   professional life.
 Kelley has thus far
 mentored three gradu-                                             or manipulated to    Q: Any words of wisdom to pass along
 ate students and con-                                             prevent acute        to your peers?
 tinues to train more                                              GVHD.
                                                                                        Be the master of your own career. Do
 students and interns in                                         Q: What inspires       not let negative people or negative
 the lab. Aside from numerous honors         you to come to work every day?             results side-track you from your goals.
 and awards during training, in 2012                                                    Science will give you a tough skin, but
                                             I absolutely LOVE my coworkers. Their
 alone Dr. Haarberg has received 1-the                                                  will also instill a sense of accomplish-
 top basic science poster award at the       insights and perpetual cooperation are
                                             encouragement for me. I come to work       ment for even the smallest of positive
 Moffitt Cancer Center Scientific Sym-
                                             every day looking forward to working       outcomes. Use those traits well and
 posium, 2- the abstract achievement                                                    you will do well.
 award at the American Society of He-        with them and to tackle challenges
 matology Annual Meeting, and 3- the         ahead whole-heartedly. I believe the
                                             field of immunology is dynamically
 top presentation award at the Univer-                                                                            —E. Sahakian
 sity of South Florida Postdoctoral Re-      evolving every day and it is an awe-
 search Colloquium. Given her busy           some time to be involved in this field




      Postdoc town hall meeting
 SAVE THE DATE: Dr. Tom Sellers will be hosting a Town Hall meeting for all Moffitt Postdocs
 on March 15, 2013. More details coming soon.
V o l u m e   2 ,   I s s u e   1                                                                                     P a g e   3



                            U p c o m i n g e v e n t :
              C a r e e r w o r k s h o p a n d i n t e r v i e w
                        p r e p a r a t i o n s e m i n a r
 Dara Wilson-Grant, Careers in             career management workshops             world renowned workshop at Mof-
 Bloom consultant, will be at Moffitt      and seminars that facilitate per-       fitt as well. Seating is limited for
 April 23, 2013 to give a seminar
 on Interview Preparation. Mrs Wil-
 son-Grant has over 15 years of                                                      • Learn general patterns in
 experience providing career coun-                                                     your interests.
 seling and career management
 education to students and profes-                                                   • Discover work
 sionals across a wide range of                                                        environments that fit your
 disciplines and career fields. She
 currently serves as the Associate
                                                                                       interests.
 Director at UNC Chapel Hill’s Of-                                                   • Explore careers that are
 fice of Postdoctoral Affairs, provid-
 ing personalized individual career                                                    consistent with your likes
 counseling to postdoctoral schol-                                                     and dislikes.
 ars. She holds a Master’s Degree
 in Counseling from Fordham Uni-                                                   the workshop. Stay tuned for more
 versity. She is also a National Cer-      sonal and profession growth, stra-      information.
 tified Counselor (NCC) and Li-            tegic planning and career ad-
 censed Professional Counselor             vancement. Her career manage-           The Interview Preparation Semi-
 Associate (LPCA).                         ment workshops have been pre-           nar, being held in the afternoon, is
                                           sented at universities, government      open to all. It is co-sponsored by
 Mrs Wilson-Grant is also the owner        agencies, and research institu-         the Moffitt Postdoctoral Associa-
 of Careers in Bloom, where she            tions, both nationally and interna-     tion and the USF Cancer Biology
 designs and presents a variety of         tionally. She will be presenting this   PhD Program.




                                    I n t e r n s h i p         o p p o r t u n i t y

 Did you know that Moffitt’s Office of Technology Manage-          resumés. Previous interns participating in the program
 ment and Commercialization (OTMC) has an internship               have leveraged this experience to gain employment in
 program?                                                          academic technology transfer offices and law firms, and
                                                                   some have even started their own businesses.
 OTMC is responsible for patenting and licensing, support-
 ing startups, and fostering industry collaborations. OTMC         Informational sessions on the OTMC internship program
 created an internship program in 2007 and to date has             are scheduled for March 19th and March 26th. Please
 hosted over 30 interns. The internship program provides           stay tuned for more information. Prior business and/or
 career development benefits to Moffitt post docs and              legal experience is not required for the internship. The
 PhD students interested in non-traditional careers (e.g.          time commitment is 4 hours per week. All postdocs and
 business development officer, patent agent, regulatory            PhD students having passed qualifying exams are eligible
 specialist, and business analyst). For interns wishing to         to apply. Additional information about the program and
 remain in academia, the experiences gained with patent-           testimonials from past interns are available at http://
 ing, licensing, and startups will be valuable and bolster         www.moffittip.com/Internship_Program.html.
V o l u m e   2 ,   I s s u e   1                                                                                              P a g e   4




        P a s t S e m i n a r : O f f i c e o f S p o n s o r e d
              R e s e a r c h ( O S R ) Q & A s e s s i o n
 On June 28th Moffitt postdocs had an          people not only asked her questions        be more than happy for postdocs to
 opportunity to have a Q & A session           but also discussed amongst each oth-       share or forward to her other postdoc-
 with Linda Nolan from OSR. This was           er the different views about applica-      toral funding opportunities as they
 a tremendous opportunity for those in         tion processes. The knowledge in the       come across them. Linda will publish
 attendance to get a better grasp of the       audience varied and provided the           those opportunities in the MRI Signals
 workings of the grants processing here        opportunity to vent the frustrations of    with other funding opportunities.
 at Moffitt as it pertains to this particu-    trying to go through this road. In this    Please feel free to forward funding
 lar time in our careers. More im-             climate of funding shortages, it is im-    opportunities that you are aware of to
 portantly, based on the changes that I        perative to give the next step in secur-   Linda (Linda.Nolan@moffitt.org).
 have seen in the MRI signals and in           ing your own funding to help your men-
                                                                                          When applying for any grant, do not
 OSR, I can say that she was very re-          tor as well as further advance your
                                                                                          wait for the submission day to contact
 ceptive to all the questions asked; she       career. It was good to learn that Linda
                                                                                          the OSR. While Linda and her team
 answered all and implemented some             and her group are ready with a helping
                                                                                          are involved in the actual processing
 suggestions made into the depart-             hand.
                                                                                          of the application, what she enjoys
 ment, such as providing more infor-
                                               Thus far, Linda and her team have          most is assisting individuals who are
 mation to us about fellowship and
                                               only been providing postdoctoral fund-     new to this research enterprise.
 career opportunities. She is very warm
                                               ing opportunities they, themselves,
 and open and hence the session took
                                               were aware of. Linda stated she would
 on a very relaxed atmosphere where




               Save the date, March 15
              Postdoc Town Hall meeting
                with Dr. Tom Seller s!!!

                          P a s t             s e m i n a r : S c i e n t i f i c
                                              c o m m u n i c a t i o n
 On November 7, 2012, the Moffitt              components of quality oral and poster      cussion, Dr. Carver provided clear
 Postdoctoral Association invited Dr.          presentations. First, she reviewed the     examples of good quality slides/
 Jane Carver to present, “Creating and         visual esthetics surrounding a presen-     posters along with some examples of
 Delivering Effective Slide Presenta-          tation, including proper font styles,      presentations that could benefit from
 tions and Posters” as a part of her           text sizes, colors, spacing, and other     the lessons learned in this seminar.
 Scientific Communication Seminar              formatting guidelines. Dr. Carver also
                                                                                          Lastly, Dr. Carver provided tips on
 Series. Preparing and delivering an           provided useful information on pre-
                                                                                          delivering an oral or poster presenta-
 oral or poster presentation is more           senting conflicts of interest, citing
                                                                                          tion. My personal favorites included
 complex than most scientists realize.         literature and borrowed materials
                                                                                          using pauses rather than ums & ahs,
 In fact, there are subtle details that        (e.g., web images), and using a critical
                                                                                          avoiding jargon, and having physical
 can substantially improve the clarity         yet often overlooked tool, SPELL-
                                                                                          copies of the abstract and/or supple-
 and effectiveness of every presenta-          CHECK! We also discussed the appro-
                                                                                          mental information in hand.
 tion.                                         priate and effective use of images,
                                               including tables, graphs, clip art, and
 In this seminar, Dr. Carver discussed
                                               photos. For nearly every point of dis-                       —C. Pierce Campbell
 the general guidelines and essential
V o l u m e   2 ,   I s s u e   1                                                                                                              P a g e   5




  U s f        p o s t d o c t o r a l                         r e s e a r c h                         c o l l o q u i u m
 The University of South Florida Post-       Allison Cohen (Cancer Imaging & Me-                  Mailloux (Immunology, PI: P.K. Epling-
 doctoral Scholar Association (USF-          tabolism, PI: David L. Morse), Yolaine               Burnette), and Eva Sahakian
 PSA) hosted their 2nd annual Postdoc-       Jeune-Smith (Cancer Imaging & Me-                    (Immunology, PIs: Eduardo M. So-
 toral Research Colloquium on Novem-         tabolism, PI: David L. Morse), Adam                  tomayor and Javier Pinella-Ibarz). The
 ber 15, 2012 at the USF Marshall                                                                                Office of Postdoctoral
 Student Center. The colloquium                                                                                  Affairs sponsored four
 brought together postdoctoral schol-                                                                            $500 travel awards to
 ars in a variety of disciplines from USF,                                                                       the posters/
 USF Health, and Moffitt Cancer Cen-                                                                             presentations that were
 ter. The purpose of the colloquium                                                                              judged to be the most
 was to provide a professional and                                                                               outstanding by a com-
 informal forum for the exchange of                                                                              mittee of faculty mem-
 ideas, research, and practice. Four                                                                             bers. Kelley Haarberg
 applicants were invited by the PSA to                                                                           was selected as one of
 give oral presentations. Kelley Haar-                                                                           the winners. The other
 berg from Xue-Zhong Yu’s group in the                                                                           winners were Ronan
 Department of Immunology was one of                                                                             Carroll (CMMB), Sandra
 the postdocs chosen. Her talk was                                                                               Acosta (Center for Ag-
 entitled “Prevention of Acute Graft-                                                                            ing), and Neha Woods
 Verses-Host Disease through Target-                                                                             (Molecular Medicine).
 ing PKC alpha and theta in Mice”. The         Left to right: A. Cohen, E. Sahakian, A. Mailloux, K. Haarberg and
                                               Y. Jeune-Smith
 colloquium also featured twenty post-
 er presentations. Among the poster                                                                                                 —A. Cohen
 presenters were four Moffitt postdocs:




          M P D A               c a r e e r           d e v e l o p m e n t                                l i b r a r y
 The Moffitt Postdoc Association has         Explaining Research: How to Reach
 created a Career Development Sec-           Key Audiences to Advance Your Work
 tion in the Moffitt Biomedical Library,     Author: Dennis Meredith
 located on the 1st floor of the MRC
                                             “So What Are You Going to Do with
 building. The MPDA has purchased
                                             That?": Finding Careers Outside Aca-
 several books, now available to loan
                                             demia
 to our postdocs. The selection in-
                                             Author: Susan Basalla and Maggie
 cludes:
                                             Debelius
 A PhD Is Not Enough!: A Guide to Sur-
                                             Marketing for Scientists – How to
 vival in Science
                                             Shine in Tough Times
 Author: Peter J. Feibelman
                                             Author: Marc Kuchner, PhD                             Career and Skill Development Books, located in
 Career Opportunities in Biotechnology                                                            the Moffitt Biomedical Library, 1st floor MRC.
                                             The Grant Application Writer's Work-
 and Drug Development
                                             book - National Institutes of Health
 Author: Toby Freedman
                                             Author: Stephen W. Russell and David
 Job Search in Academe: Strategic            C. Morrison                                          Come visit and check out the full se-
 Rhetorics for Faculty Job Candidates                                                             lection. If assistance is needed, ask
 Author: Formo Dawn M                                                                             Susan the Librarian.
V o l u m e   2 ,   I s s u e   1                                                                                           P a g e   6




                                F e a t u r e d             p u b l i c a t i o n s
 Christie J Quinn GP, Malo T, Lee JH, Zhao X, McIntyre J, Brzosowicz J, Jacobsen PB and Vadaparampil ST. Cognitive and psycho-
          J,
 logical impact of BRCA genetic counseling in before and after definitive surgery breast cancer patients. Annals of Surgical On-
 cology. 2012 Dec;19(13):4003-4011

 Jim HS, Phillips KM Chait S, Faul LA, Popa-McKiver MA, Lee YH, Hussin MG, Jacobsen PB and Small BJ. Meta-analysis of cogni-
                  KM,
 tive functioning in breast cancer survivors previously treated with standard-dose chemotherapy. Journal of Clinical Oncology.
 2012 Oct; 30(29):3578-3587

 Kang CW Sun Y and Del Valle JR. Substituted Imidazo[1,2-a]pyridines as B-strand peptidomimetics. Organic Letters. 2012 Oct;
      CW,
 14(24):6162-6165

 Kodumudi KN Weber A, Sarnaik AA, Pilon-Thomas S. Blockade of myeloid-derived suppressor cells after induction of lymphope-
           KN,
 nia improves adoptive T cell therapy in a murine model of melanoma. Journal of Immunology. 2012 Dec; 189(11):5147-5154

 Pierce Campbell CM, Menezes LJ, Paskett ED and Giuliano AR. Prevention of invasive cervical cancer in the United States: Past,
                  CM
 present, and future. Cancer Epidemiology Biomarkers & Prevention. 2012 Sep; 21(9):1402-1408

 Vadaparampil ST, Malo T, de la Cruz C and Christie J Do breast cancer patients tested in the oncology care setting share BRCA
                                                    J.
 mutation results with family members and health care providers? Journal of Cancer Epidemiology. 2012 July 15 [Epub ahead
 of print] DOI: 10.1155/2012/498062

 Vadaparampil ST, Staras SA, Malo TL, Eddleton KZ, Christie J Rodriguez M, Giuliano AR and Shenkman EA. Provider factors
                                                            J,
 associated with disparities in human papillomavirus vaccination among low-income 9-17-year-old girls. Cancer. 2012 Aug 1.
 [Epub ahead of print] DOI: 10.1002/cncr.27735

 Wang D, Iclozan C, Liu C, Xia C, Anasetti C and Yu XZ. LBH589 enhances T-cell activation in vivo and accelerates graft-versus-
                 C
 host disease in mice. Biology of Blood and Marrow Transplantion. 2012 Aug; 18(8): 1182-1190.e1

 Woods NT Mesquita RD, Sweet M, Carvalho MA, Li X, Liu Y, Nguyen H, Thomas CE, Iversen ES Jr., Marsillac S, Karchin R,
       NT,
 Koomen J and Monteiro AN. Charting the landscape of tandem BRCT domain–mediated protein interactions. Science Signaling.
 2012 Sep; 5(242):rs6

 Wu S Chen L, Becker A, Schonbrunn E and Chen J. Casein kinase 1α regulates an MDMX intramolecular interaction to stimu-
     S,
 late p53 binding. Molecular and Cellular Biology. 2012 Dec; 32(23):4821-4832

 Youn JI Kumar V Collazo M, Nefedova Y, Condamine T Cheng C, Villagra A, Antonia S, McCaffrey JC, Fishman M, Sarnaik A,
      JI,         V,                                  T,
 Horna P, Sotomayor E and Gabrilovich DI. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of
 myeloid cells in cancer. Nature Immunology. 2012 January 27 [Epub ahead of print] DOI: 10.1038/ni.2526




                                    M P D A        s e m i n a r              s e r i e s


 To give postdocs here at Moffitt an opportunity to practice their presentation skills, the Moffitt Postdoctoral Association has
 created a seminar series. Postdocs can sign up to present their research to the Moffitt scientific community during this month-
 ly seminar, generally the 3rd Thursday at 4pm. This provides a venue through which you can receive feedback on speaking
 skills and to foster collaborations with postdocs from other labs. If you are interested in participating, email Cathy Gaffney
 (Cathy.Gaffney@moffitt.org); please be sure to inform your mentor as this will be publicized in MRI Signals and on the electronic
 signs throughout Moffitt. This presentation can be added to your CV and included on your annual review in Halogen.
IT’S YOUR FUTURE, GET
                                                       INVOLVED!!!



  H .  L E E  M O F F I T T
  C A N C E R  C E N T E R                                        The mission of the Moffitt Postdoctoral Associa-
                                                                  tion (MPDA) is to foster professional development
  Moffitt Postdoctoral Association
  12902 Magnolia Drive                                            and social interaction and to provide a collective
  MRC 4                                                           voice and liaison between postdoctoral fellows,
  Tampa, Fl 33612
                                                                  faculty and administration.
  E-mail: pdaofmcc@moffitt.org
                                                                  CREDITS: A. Cohen, L. Cook, D. Cress, E. Eksioglu,
                                                                  C. Gaffney, Y. Jeune-Smith, C. Pierce Campbell,
                                                                  E. Sahakian and G. Shay

  Its your future. Get involved!!!




                        M p d a c o u n c i l l e a d e r s h i p
                            w i n t e r / s p r i n g 2 0 1 3
Chair: Leah M. Cook
PhD earned in Molecular and Cellular Pathology from the University of Alabama, Birmingham, AL
Current Lab: Conor Lynch, PhD Tumor Biology/Molecular Oncology
Current Research: One of the focuses of the Lynch Lab is to understand the molecular dynamics of prostate cancer metastasis
to bone. They aim to gain an understanding of mechanisms involved in the progression and survival of metastatic prostate
cancer within bone and are exploring novel therapeutic targets for treating this disease. Leah is currently working with David
Basanta, in the Department of Mathematical Oncology, to explore new methods for targeting prostate cancer metastasis.

Vice Chair: Gemma Shay
PhD earned in Medicine and Therapeutics from the University of Aberdeen, Scotland, UK
Current Lab: Conor Lynch, PhD Tumor Biology/Molecular Oncology
Current Research: Gemma is looking at the roles of MMPs in bone cancer metastasis and making use of novel bone-seeking
MMP-2 inhibitors for the treatment of myeloma




        N e w         p o s t d o c s               o f      s u m m e r / f a l l                     2 0 1 2
                     Name            Department                                                    PI/Lab
     Ying Han                Immunology                                               Burnette
     Arturo Araujo Gutierrez Mathematical Oncology                                    Basanta
     Zili Wang               Immunology                                               Celis
     Michael Emmons          Molecular Oncology                                       Hazlehurst
     Hua Wang                Imaging                                                  Gillies
     Manali Phadke           Molecular Oncology                                       Smalley
     Hemachander Subramanian Imaging                                                  Gatenby
     Jacob Scott             Mathematical Oncology                                    Anderson
     Yixuan Li               Molecular Oncology                                       Seto

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MPDA e-newlsetter 2013 jan 31

  • 1. Volume 2, Issue 1 31 January 2013 MPDA e-Newsletter H . L E E M O F F I T T C A N C E R C E N T E R S A V E T H E D A T E S S c i e n t i f i c s u b m i s s i o n s t u d i o ( S 3 ) • March 15, 2013 Postdoc Town Hall With all of the pressures in editors and scientific writ- grant to the review board, with Dr. Sellers science to publish quality ers). and distribute reviewer • April 23, 2013 work and to successfully comments back to the sub- Career Workshop acquire funding, don’t you How does it work? mitter. The S3 board will and Interview Prepa- wish that you had some- An S3 request form with the meet to review submissions ration Seminar thing that could boost your following information: an every 3rd Thursday of the chances while also provid- abstract of the submission, month. Individuals must ing you with the necessary proposed journal of submis- request an S3 review no developmental tools to im- sion, and a proposed panel less than two months be- I N S I D E T H I S I S S U E : prove your writing? of reviewers (first and se- fore the proposed submis- cond choice of Moffitt facul- sion to allow substantial Postdoc Spotlight 2 Where can I find something ty) of the submitter’s choos- time for review and distribu- like this? ing will be submitted to the tion of comments back to Town Hall Meeting 2 The Moffitt Postdoctoral S3 portal on the MPDA web- the submitter. Career Workshop; Association would like to site. Potential reviewers will Interview Preparation 3 Seminar present S3 (Scientific Sub- be asked to respond within This sounds great. When mission Studio), an internal a week of inquiry; upon will it start? Internship Opportunity 3 review board designed as a acceptance, the submitter The MPDA is currently in tool for junior scientists to will provide a publication- the planning process for S3 OSR Q&A Session 4 improve upon the quality of ready manuscript to the and are in need of eager Scientific Communica- 4 manuscripts and grant pro- MPDA who will distribute scientists ready to submit tion Seminar Series posal submissions. With S3, the work to the review their work and senior Mof- Research Colloquium 5 junior scientists at Moffitt board members. Submit- fitt members willing to pro- (including: postdoctoral ters must have the permis- vide their expertise and a Career & Skill Develop- 5 fellows, graduate students, sion and signature of ap- little time to help review ment Resource Library and research assistants) proval from his or her pri- submitted work. With a little Featured Publications 6 can receive feedback on mary mentor on the re- help from our wonderful publication-ready manu- quest. The MPDA will pro- Moffitt team, we are hoping MPDA Seminar Series 6 scripts from a pre-approved vide the request form, facili- to launch this new service MPDA Council, New committee comprised of tate the assembling of the this upcoming fall. 7 Leadership members of our Moffitt review board members, —L. Cook New Postdocs 7 team (experienced journal distribute the manuscript or
  • 2. V o l u m e 2 , I s s u e 1 P a g e 2 P o s t d o c s p o t l i g h t This quarter’s Postdoc Spotlight fea- and packed schedule, I was very grate- of research. I am thankful for Dr. Yu’s tures Dr. Kelley M.K. Haarberg. Cur- ful to have a chance to sit down with support in my work and appreciate his rently, Kelley trains as a 3rd year re- Kelley for a few minutes and ask her a backing and mentorship. search fellow in the laboratory of a few questions about her experiences Q: What is your greatest daily chal- well-regarded Moffitt Cancer Center here at Moffitt. lenge? investigator, Dr. Yu. Dr. Yu’s laboratory Q: What are your research goals and is actively involved in ground-breaking My greatest daily challenge is making tell us a bit about your project? research in the field of graft-versus- sure my experiments flow and that I host disease (GVHD). Dr. Haarberg has We have just wrapped up a line of have planned them correctly and I more than eight years of basic science investigations involving genetic and execute them with efficacy and dili- research experience in cellular and pharmacologic PKCα and PKCθ inhibi- gence. In my field of work, remaining molecular biology, microbiology and tion to dampen detrimental alloreac- focused is the key to success. It is very immunology and more tivity in the con- easy to get side-tracked as we get very than five years of clini- text of acute passionate about what we do. cal/patient care experi- GVHD. I am most Q: How do you like to spend your “Me ence. Her project cur- recently opening time”? rently is to develop a new line of in- vestigation to Well, I have been blessed with many genetic and pharmaco- explore the meta- things in my life so far but, the most logic T-cell manipula- bolic profiles of important thing in my life is my daugh- tion strategies to pre- alloreactive T ter. I love spending time with her and vent acute GVHD. In cells and how T my family. What completes me and addition to everyday cell metabolism gives me the resolve to do what I do is laborious post-doctoral contributes to and to maintain a balanced personal and research obligations, could be exploited professional life. Kelley has thus far mentored three gradu- or manipulated to Q: Any words of wisdom to pass along ate students and con- prevent acute to your peers? tinues to train more GVHD. Be the master of your own career. Do students and interns in Q: What inspires not let negative people or negative the lab. Aside from numerous honors you to come to work every day? results side-track you from your goals. and awards during training, in 2012 Science will give you a tough skin, but I absolutely LOVE my coworkers. Their alone Dr. Haarberg has received 1-the will also instill a sense of accomplish- top basic science poster award at the insights and perpetual cooperation are encouragement for me. I come to work ment for even the smallest of positive Moffitt Cancer Center Scientific Sym- every day looking forward to working outcomes. Use those traits well and posium, 2- the abstract achievement you will do well. award at the American Society of He- with them and to tackle challenges matology Annual Meeting, and 3- the ahead whole-heartedly. I believe the field of immunology is dynamically top presentation award at the Univer- —E. Sahakian sity of South Florida Postdoctoral Re- evolving every day and it is an awe- search Colloquium. Given her busy some time to be involved in this field Postdoc town hall meeting SAVE THE DATE: Dr. Tom Sellers will be hosting a Town Hall meeting for all Moffitt Postdocs on March 15, 2013. More details coming soon.
  • 3. V o l u m e 2 , I s s u e 1 P a g e 3 U p c o m i n g e v e n t : C a r e e r w o r k s h o p a n d i n t e r v i e w p r e p a r a t i o n s e m i n a r Dara Wilson-Grant, Careers in career management workshops world renowned workshop at Mof- Bloom consultant, will be at Moffitt and seminars that facilitate per- fitt as well. Seating is limited for April 23, 2013 to give a seminar on Interview Preparation. Mrs Wil- son-Grant has over 15 years of • Learn general patterns in experience providing career coun- your interests. seling and career management education to students and profes- • Discover work sionals across a wide range of environments that fit your disciplines and career fields. She currently serves as the Associate interests. Director at UNC Chapel Hill’s Of- • Explore careers that are fice of Postdoctoral Affairs, provid- ing personalized individual career consistent with your likes counseling to postdoctoral schol- and dislikes. ars. She holds a Master’s Degree in Counseling from Fordham Uni- the workshop. Stay tuned for more versity. She is also a National Cer- sonal and profession growth, stra- information. tified Counselor (NCC) and Li- tegic planning and career ad- censed Professional Counselor vancement. Her career manage- The Interview Preparation Semi- Associate (LPCA). ment workshops have been pre- nar, being held in the afternoon, is sented at universities, government open to all. It is co-sponsored by Mrs Wilson-Grant is also the owner agencies, and research institu- the Moffitt Postdoctoral Associa- of Careers in Bloom, where she tions, both nationally and interna- tion and the USF Cancer Biology designs and presents a variety of tionally. She will be presenting this PhD Program. I n t e r n s h i p o p p o r t u n i t y Did you know that Moffitt’s Office of Technology Manage- resumés. Previous interns participating in the program ment and Commercialization (OTMC) has an internship have leveraged this experience to gain employment in program? academic technology transfer offices and law firms, and some have even started their own businesses. OTMC is responsible for patenting and licensing, support- ing startups, and fostering industry collaborations. OTMC Informational sessions on the OTMC internship program created an internship program in 2007 and to date has are scheduled for March 19th and March 26th. Please hosted over 30 interns. The internship program provides stay tuned for more information. Prior business and/or career development benefits to Moffitt post docs and legal experience is not required for the internship. The PhD students interested in non-traditional careers (e.g. time commitment is 4 hours per week. All postdocs and business development officer, patent agent, regulatory PhD students having passed qualifying exams are eligible specialist, and business analyst). For interns wishing to to apply. Additional information about the program and remain in academia, the experiences gained with patent- testimonials from past interns are available at http:// ing, licensing, and startups will be valuable and bolster www.moffittip.com/Internship_Program.html.
  • 4. V o l u m e 2 , I s s u e 1 P a g e 4 P a s t S e m i n a r : O f f i c e o f S p o n s o r e d R e s e a r c h ( O S R ) Q & A s e s s i o n On June 28th Moffitt postdocs had an people not only asked her questions be more than happy for postdocs to opportunity to have a Q & A session but also discussed amongst each oth- share or forward to her other postdoc- with Linda Nolan from OSR. This was er the different views about applica- toral funding opportunities as they a tremendous opportunity for those in tion processes. The knowledge in the come across them. Linda will publish attendance to get a better grasp of the audience varied and provided the those opportunities in the MRI Signals workings of the grants processing here opportunity to vent the frustrations of with other funding opportunities. at Moffitt as it pertains to this particu- trying to go through this road. In this Please feel free to forward funding lar time in our careers. More im- climate of funding shortages, it is im- opportunities that you are aware of to portantly, based on the changes that I perative to give the next step in secur- Linda (Linda.Nolan@moffitt.org). have seen in the MRI signals and in ing your own funding to help your men- When applying for any grant, do not OSR, I can say that she was very re- tor as well as further advance your wait for the submission day to contact ceptive to all the questions asked; she career. It was good to learn that Linda the OSR. While Linda and her team answered all and implemented some and her group are ready with a helping are involved in the actual processing suggestions made into the depart- hand. of the application, what she enjoys ment, such as providing more infor- Thus far, Linda and her team have most is assisting individuals who are mation to us about fellowship and only been providing postdoctoral fund- new to this research enterprise. career opportunities. She is very warm ing opportunities they, themselves, and open and hence the session took were aware of. Linda stated she would on a very relaxed atmosphere where Save the date, March 15 Postdoc Town Hall meeting with Dr. Tom Seller s!!! P a s t s e m i n a r : S c i e n t i f i c c o m m u n i c a t i o n On November 7, 2012, the Moffitt components of quality oral and poster cussion, Dr. Carver provided clear Postdoctoral Association invited Dr. presentations. First, she reviewed the examples of good quality slides/ Jane Carver to present, “Creating and visual esthetics surrounding a presen- posters along with some examples of Delivering Effective Slide Presenta- tation, including proper font styles, presentations that could benefit from tions and Posters” as a part of her text sizes, colors, spacing, and other the lessons learned in this seminar. Scientific Communication Seminar formatting guidelines. Dr. Carver also Lastly, Dr. Carver provided tips on Series. Preparing and delivering an provided useful information on pre- delivering an oral or poster presenta- oral or poster presentation is more senting conflicts of interest, citing tion. My personal favorites included complex than most scientists realize. literature and borrowed materials using pauses rather than ums & ahs, In fact, there are subtle details that (e.g., web images), and using a critical avoiding jargon, and having physical can substantially improve the clarity yet often overlooked tool, SPELL- copies of the abstract and/or supple- and effectiveness of every presenta- CHECK! We also discussed the appro- mental information in hand. tion. priate and effective use of images, including tables, graphs, clip art, and In this seminar, Dr. Carver discussed photos. For nearly every point of dis- —C. Pierce Campbell the general guidelines and essential
  • 5. V o l u m e 2 , I s s u e 1 P a g e 5 U s f p o s t d o c t o r a l r e s e a r c h c o l l o q u i u m The University of South Florida Post- Allison Cohen (Cancer Imaging & Me- Mailloux (Immunology, PI: P.K. Epling- doctoral Scholar Association (USF- tabolism, PI: David L. Morse), Yolaine Burnette), and Eva Sahakian PSA) hosted their 2nd annual Postdoc- Jeune-Smith (Cancer Imaging & Me- (Immunology, PIs: Eduardo M. So- toral Research Colloquium on Novem- tabolism, PI: David L. Morse), Adam tomayor and Javier Pinella-Ibarz). The ber 15, 2012 at the USF Marshall Office of Postdoctoral Student Center. The colloquium Affairs sponsored four brought together postdoctoral schol- $500 travel awards to ars in a variety of disciplines from USF, the posters/ USF Health, and Moffitt Cancer Cen- presentations that were ter. The purpose of the colloquium judged to be the most was to provide a professional and outstanding by a com- informal forum for the exchange of mittee of faculty mem- ideas, research, and practice. Four bers. Kelley Haarberg applicants were invited by the PSA to was selected as one of give oral presentations. Kelley Haar- the winners. The other berg from Xue-Zhong Yu’s group in the winners were Ronan Department of Immunology was one of Carroll (CMMB), Sandra the postdocs chosen. Her talk was Acosta (Center for Ag- entitled “Prevention of Acute Graft- ing), and Neha Woods Verses-Host Disease through Target- (Molecular Medicine). ing PKC alpha and theta in Mice”. The Left to right: A. Cohen, E. Sahakian, A. Mailloux, K. Haarberg and Y. Jeune-Smith colloquium also featured twenty post- er presentations. Among the poster —A. Cohen presenters were four Moffitt postdocs: M P D A c a r e e r d e v e l o p m e n t l i b r a r y The Moffitt Postdoc Association has Explaining Research: How to Reach created a Career Development Sec- Key Audiences to Advance Your Work tion in the Moffitt Biomedical Library, Author: Dennis Meredith located on the 1st floor of the MRC “So What Are You Going to Do with building. The MPDA has purchased That?": Finding Careers Outside Aca- several books, now available to loan demia to our postdocs. The selection in- Author: Susan Basalla and Maggie cludes: Debelius A PhD Is Not Enough!: A Guide to Sur- Marketing for Scientists – How to vival in Science Shine in Tough Times Author: Peter J. Feibelman Author: Marc Kuchner, PhD Career and Skill Development Books, located in Career Opportunities in Biotechnology the Moffitt Biomedical Library, 1st floor MRC. The Grant Application Writer's Work- and Drug Development book - National Institutes of Health Author: Toby Freedman Author: Stephen W. Russell and David Job Search in Academe: Strategic C. Morrison Come visit and check out the full se- Rhetorics for Faculty Job Candidates lection. If assistance is needed, ask Author: Formo Dawn M Susan the Librarian.
  • 6. V o l u m e 2 , I s s u e 1 P a g e 6 F e a t u r e d p u b l i c a t i o n s Christie J Quinn GP, Malo T, Lee JH, Zhao X, McIntyre J, Brzosowicz J, Jacobsen PB and Vadaparampil ST. Cognitive and psycho- J, logical impact of BRCA genetic counseling in before and after definitive surgery breast cancer patients. Annals of Surgical On- cology. 2012 Dec;19(13):4003-4011 Jim HS, Phillips KM Chait S, Faul LA, Popa-McKiver MA, Lee YH, Hussin MG, Jacobsen PB and Small BJ. Meta-analysis of cogni- KM, tive functioning in breast cancer survivors previously treated with standard-dose chemotherapy. Journal of Clinical Oncology. 2012 Oct; 30(29):3578-3587 Kang CW Sun Y and Del Valle JR. Substituted Imidazo[1,2-a]pyridines as B-strand peptidomimetics. Organic Letters. 2012 Oct; CW, 14(24):6162-6165 Kodumudi KN Weber A, Sarnaik AA, Pilon-Thomas S. Blockade of myeloid-derived suppressor cells after induction of lymphope- KN, nia improves adoptive T cell therapy in a murine model of melanoma. Journal of Immunology. 2012 Dec; 189(11):5147-5154 Pierce Campbell CM, Menezes LJ, Paskett ED and Giuliano AR. Prevention of invasive cervical cancer in the United States: Past, CM present, and future. Cancer Epidemiology Biomarkers & Prevention. 2012 Sep; 21(9):1402-1408 Vadaparampil ST, Malo T, de la Cruz C and Christie J Do breast cancer patients tested in the oncology care setting share BRCA J. mutation results with family members and health care providers? Journal of Cancer Epidemiology. 2012 July 15 [Epub ahead of print] DOI: 10.1155/2012/498062 Vadaparampil ST, Staras SA, Malo TL, Eddleton KZ, Christie J Rodriguez M, Giuliano AR and Shenkman EA. Provider factors J, associated with disparities in human papillomavirus vaccination among low-income 9-17-year-old girls. Cancer. 2012 Aug 1. [Epub ahead of print] DOI: 10.1002/cncr.27735 Wang D, Iclozan C, Liu C, Xia C, Anasetti C and Yu XZ. LBH589 enhances T-cell activation in vivo and accelerates graft-versus- C host disease in mice. Biology of Blood and Marrow Transplantion. 2012 Aug; 18(8): 1182-1190.e1 Woods NT Mesquita RD, Sweet M, Carvalho MA, Li X, Liu Y, Nguyen H, Thomas CE, Iversen ES Jr., Marsillac S, Karchin R, NT, Koomen J and Monteiro AN. Charting the landscape of tandem BRCT domain–mediated protein interactions. Science Signaling. 2012 Sep; 5(242):rs6 Wu S Chen L, Becker A, Schonbrunn E and Chen J. Casein kinase 1α regulates an MDMX intramolecular interaction to stimu- S, late p53 binding. Molecular and Cellular Biology. 2012 Dec; 32(23):4821-4832 Youn JI Kumar V Collazo M, Nefedova Y, Condamine T Cheng C, Villagra A, Antonia S, McCaffrey JC, Fishman M, Sarnaik A, JI, V, T, Horna P, Sotomayor E and Gabrilovich DI. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Nature Immunology. 2012 January 27 [Epub ahead of print] DOI: 10.1038/ni.2526 M P D A s e m i n a r s e r i e s To give postdocs here at Moffitt an opportunity to practice their presentation skills, the Moffitt Postdoctoral Association has created a seminar series. Postdocs can sign up to present their research to the Moffitt scientific community during this month- ly seminar, generally the 3rd Thursday at 4pm. This provides a venue through which you can receive feedback on speaking skills and to foster collaborations with postdocs from other labs. If you are interested in participating, email Cathy Gaffney (Cathy.Gaffney@moffitt.org); please be sure to inform your mentor as this will be publicized in MRI Signals and on the electronic signs throughout Moffitt. This presentation can be added to your CV and included on your annual review in Halogen.
  • 7. IT’S YOUR FUTURE, GET INVOLVED!!! H . L E E M O F F I T T C A N C E R C E N T E R The mission of the Moffitt Postdoctoral Associa- tion (MPDA) is to foster professional development Moffitt Postdoctoral Association 12902 Magnolia Drive and social interaction and to provide a collective MRC 4 voice and liaison between postdoctoral fellows, Tampa, Fl 33612 faculty and administration. E-mail: pdaofmcc@moffitt.org CREDITS: A. Cohen, L. Cook, D. Cress, E. Eksioglu, C. Gaffney, Y. Jeune-Smith, C. Pierce Campbell, E. Sahakian and G. Shay Its your future. Get involved!!! M p d a c o u n c i l l e a d e r s h i p w i n t e r / s p r i n g 2 0 1 3 Chair: Leah M. Cook PhD earned in Molecular and Cellular Pathology from the University of Alabama, Birmingham, AL Current Lab: Conor Lynch, PhD Tumor Biology/Molecular Oncology Current Research: One of the focuses of the Lynch Lab is to understand the molecular dynamics of prostate cancer metastasis to bone. They aim to gain an understanding of mechanisms involved in the progression and survival of metastatic prostate cancer within bone and are exploring novel therapeutic targets for treating this disease. Leah is currently working with David Basanta, in the Department of Mathematical Oncology, to explore new methods for targeting prostate cancer metastasis. Vice Chair: Gemma Shay PhD earned in Medicine and Therapeutics from the University of Aberdeen, Scotland, UK Current Lab: Conor Lynch, PhD Tumor Biology/Molecular Oncology Current Research: Gemma is looking at the roles of MMPs in bone cancer metastasis and making use of novel bone-seeking MMP-2 inhibitors for the treatment of myeloma N e w p o s t d o c s o f s u m m e r / f a l l 2 0 1 2 Name Department PI/Lab Ying Han Immunology Burnette Arturo Araujo Gutierrez Mathematical Oncology Basanta Zili Wang Immunology Celis Michael Emmons Molecular Oncology Hazlehurst Hua Wang Imaging Gillies Manali Phadke Molecular Oncology Smalley Hemachander Subramanian Imaging Gatenby Jacob Scott Mathematical Oncology Anderson Yixuan Li Molecular Oncology Seto