1. Volume 2, Issue 1 31 January 2013
MPDA e-Newsletter
H . L E E M O F F I T T C A N C E R C E N T E R
S A V E T H E
D A T E S S c i e n t i f i c s u b m i s s i o n s t u d i o
( S 3 )
• March 15, 2013
Postdoc Town Hall With all of the pressures in editors and scientific writ- grant to the review board,
with Dr. Sellers science to publish quality ers). and distribute reviewer
• April 23, 2013 work and to successfully comments back to the sub-
Career Workshop acquire funding, don’t you How does it work? mitter. The S3 board will
and Interview Prepa- wish that you had some- An S3 request form with the meet to review submissions
ration Seminar
thing that could boost your following information: an every 3rd Thursday of the
chances while also provid- abstract of the submission, month. Individuals must
ing you with the necessary proposed journal of submis- request an S3 review no
developmental tools to im- sion, and a proposed panel less than two months be-
I N S I D E T H I S
I S S U E :
prove your writing? of reviewers (first and se- fore the proposed submis-
cond choice of Moffitt facul- sion to allow substantial
Postdoc Spotlight 2 Where can I find something ty) of the submitter’s choos- time for review and distribu-
like this? ing will be submitted to the tion of comments back to
Town Hall Meeting 2
The Moffitt Postdoctoral S3 portal on the MPDA web- the submitter.
Career Workshop; Association would like to site. Potential reviewers will
Interview Preparation 3
Seminar present S3 (Scientific Sub- be asked to respond within This sounds great. When
mission Studio), an internal a week of inquiry; upon will it start?
Internship Opportunity 3 review board designed as a acceptance, the submitter The MPDA is currently in
tool for junior scientists to will provide a publication- the planning process for S3
OSR Q&A Session 4
improve upon the quality of ready manuscript to the and are in need of eager
Scientific Communica-
4
manuscripts and grant pro- MPDA who will distribute scientists ready to submit
tion Seminar Series
posal submissions. With S3, the work to the review their work and senior Mof-
Research Colloquium 5 junior scientists at Moffitt board members. Submit- fitt members willing to pro-
(including: postdoctoral ters must have the permis- vide their expertise and a
Career & Skill Develop-
5 fellows, graduate students, sion and signature of ap- little time to help review
ment Resource Library
and research assistants) proval from his or her pri- submitted work. With a little
Featured Publications 6 can receive feedback on mary mentor on the re- help from our wonderful
publication-ready manu- quest. The MPDA will pro- Moffitt team, we are hoping
MPDA Seminar Series 6
scripts from a pre-approved vide the request form, facili- to launch this new service
MPDA Council, New committee comprised of tate the assembling of the this upcoming fall.
7
Leadership
members of our Moffitt review board members, —L. Cook
New Postdocs 7 team (experienced journal distribute the manuscript or
2. V o l u m e 2 , I s s u e 1 P a g e 2
P o s t d o c s p o t l i g h t
This quarter’s Postdoc Spotlight fea- and packed schedule, I was very grate- of research. I am thankful for Dr. Yu’s
tures Dr. Kelley M.K. Haarberg. Cur- ful to have a chance to sit down with support in my work and appreciate his
rently, Kelley trains as a 3rd year re- Kelley for a few minutes and ask her a backing and mentorship.
search fellow in the laboratory of a few questions about her experiences
Q: What is your greatest daily chal-
well-regarded Moffitt Cancer Center here at Moffitt.
lenge?
investigator, Dr. Yu. Dr. Yu’s laboratory
Q: What are your research goals and
is actively involved in ground-breaking My greatest daily challenge is making
tell us a bit about your project?
research in the field of graft-versus- sure my experiments flow and that I
host disease (GVHD). Dr. Haarberg has We have just wrapped up a line of have planned them correctly and I
more than eight years of basic science investigations involving genetic and execute them with efficacy and dili-
research experience in cellular and pharmacologic PKCα and PKCθ inhibi- gence. In my field of work, remaining
molecular biology, microbiology and tion to dampen detrimental alloreac- focused is the key to success. It is very
immunology and more tivity in the con- easy to get side-tracked as we get very
than five years of clini- text of acute passionate about what we do.
cal/patient care experi- GVHD. I am most Q: How do you like to spend your “Me
ence. Her project cur- recently opening time”?
rently is to develop a new line of in-
vestigation to Well, I have been blessed with many
genetic and pharmaco-
explore the meta- things in my life so far but, the most
logic T-cell manipula-
bolic profiles of important thing in my life is my daugh-
tion strategies to pre-
alloreactive T ter. I love spending time with her and
vent acute GVHD. In
cells and how T my family. What completes me and
addition to everyday
cell metabolism gives me the resolve to do what I do is
laborious post-doctoral
contributes to and to maintain a balanced personal and
research obligations,
could be exploited professional life.
Kelley has thus far
mentored three gradu- or manipulated to Q: Any words of wisdom to pass along
ate students and con- prevent acute to your peers?
tinues to train more GVHD.
Be the master of your own career. Do
students and interns in Q: What inspires not let negative people or negative
the lab. Aside from numerous honors you to come to work every day? results side-track you from your goals.
and awards during training, in 2012 Science will give you a tough skin, but
I absolutely LOVE my coworkers. Their
alone Dr. Haarberg has received 1-the will also instill a sense of accomplish-
top basic science poster award at the insights and perpetual cooperation are
encouragement for me. I come to work ment for even the smallest of positive
Moffitt Cancer Center Scientific Sym-
every day looking forward to working outcomes. Use those traits well and
posium, 2- the abstract achievement you will do well.
award at the American Society of He- with them and to tackle challenges
matology Annual Meeting, and 3- the ahead whole-heartedly. I believe the
field of immunology is dynamically
top presentation award at the Univer- —E. Sahakian
sity of South Florida Postdoctoral Re- evolving every day and it is an awe-
search Colloquium. Given her busy some time to be involved in this field
Postdoc town hall meeting
SAVE THE DATE: Dr. Tom Sellers will be hosting a Town Hall meeting for all Moffitt Postdocs
on March 15, 2013. More details coming soon.
3. V o l u m e 2 , I s s u e 1 P a g e 3
U p c o m i n g e v e n t :
C a r e e r w o r k s h o p a n d i n t e r v i e w
p r e p a r a t i o n s e m i n a r
Dara Wilson-Grant, Careers in career management workshops world renowned workshop at Mof-
Bloom consultant, will be at Moffitt and seminars that facilitate per- fitt as well. Seating is limited for
April 23, 2013 to give a seminar
on Interview Preparation. Mrs Wil-
son-Grant has over 15 years of • Learn general patterns in
experience providing career coun- your interests.
seling and career management
education to students and profes- • Discover work
sionals across a wide range of environments that fit your
disciplines and career fields. She
currently serves as the Associate
interests.
Director at UNC Chapel Hill’s Of- • Explore careers that are
fice of Postdoctoral Affairs, provid-
ing personalized individual career consistent with your likes
counseling to postdoctoral schol- and dislikes.
ars. She holds a Master’s Degree
in Counseling from Fordham Uni- the workshop. Stay tuned for more
versity. She is also a National Cer- sonal and profession growth, stra- information.
tified Counselor (NCC) and Li- tegic planning and career ad-
censed Professional Counselor vancement. Her career manage- The Interview Preparation Semi-
Associate (LPCA). ment workshops have been pre- nar, being held in the afternoon, is
sented at universities, government open to all. It is co-sponsored by
Mrs Wilson-Grant is also the owner agencies, and research institu- the Moffitt Postdoctoral Associa-
of Careers in Bloom, where she tions, both nationally and interna- tion and the USF Cancer Biology
designs and presents a variety of tionally. She will be presenting this PhD Program.
I n t e r n s h i p o p p o r t u n i t y
Did you know that Moffitt’s Office of Technology Manage- resumés. Previous interns participating in the program
ment and Commercialization (OTMC) has an internship have leveraged this experience to gain employment in
program? academic technology transfer offices and law firms, and
some have even started their own businesses.
OTMC is responsible for patenting and licensing, support-
ing startups, and fostering industry collaborations. OTMC Informational sessions on the OTMC internship program
created an internship program in 2007 and to date has are scheduled for March 19th and March 26th. Please
hosted over 30 interns. The internship program provides stay tuned for more information. Prior business and/or
career development benefits to Moffitt post docs and legal experience is not required for the internship. The
PhD students interested in non-traditional careers (e.g. time commitment is 4 hours per week. All postdocs and
business development officer, patent agent, regulatory PhD students having passed qualifying exams are eligible
specialist, and business analyst). For interns wishing to to apply. Additional information about the program and
remain in academia, the experiences gained with patent- testimonials from past interns are available at http://
ing, licensing, and startups will be valuable and bolster www.moffittip.com/Internship_Program.html.
4. V o l u m e 2 , I s s u e 1 P a g e 4
P a s t S e m i n a r : O f f i c e o f S p o n s o r e d
R e s e a r c h ( O S R ) Q & A s e s s i o n
On June 28th Moffitt postdocs had an people not only asked her questions be more than happy for postdocs to
opportunity to have a Q & A session but also discussed amongst each oth- share or forward to her other postdoc-
with Linda Nolan from OSR. This was er the different views about applica- toral funding opportunities as they
a tremendous opportunity for those in tion processes. The knowledge in the come across them. Linda will publish
attendance to get a better grasp of the audience varied and provided the those opportunities in the MRI Signals
workings of the grants processing here opportunity to vent the frustrations of with other funding opportunities.
at Moffitt as it pertains to this particu- trying to go through this road. In this Please feel free to forward funding
lar time in our careers. More im- climate of funding shortages, it is im- opportunities that you are aware of to
portantly, based on the changes that I perative to give the next step in secur- Linda (Linda.Nolan@moffitt.org).
have seen in the MRI signals and in ing your own funding to help your men-
When applying for any grant, do not
OSR, I can say that she was very re- tor as well as further advance your
wait for the submission day to contact
ceptive to all the questions asked; she career. It was good to learn that Linda
the OSR. While Linda and her team
answered all and implemented some and her group are ready with a helping
are involved in the actual processing
suggestions made into the depart- hand.
of the application, what she enjoys
ment, such as providing more infor-
Thus far, Linda and her team have most is assisting individuals who are
mation to us about fellowship and
only been providing postdoctoral fund- new to this research enterprise.
career opportunities. She is very warm
ing opportunities they, themselves,
and open and hence the session took
were aware of. Linda stated she would
on a very relaxed atmosphere where
Save the date, March 15
Postdoc Town Hall meeting
with Dr. Tom Seller s!!!
P a s t s e m i n a r : S c i e n t i f i c
c o m m u n i c a t i o n
On November 7, 2012, the Moffitt components of quality oral and poster cussion, Dr. Carver provided clear
Postdoctoral Association invited Dr. presentations. First, she reviewed the examples of good quality slides/
Jane Carver to present, “Creating and visual esthetics surrounding a presen- posters along with some examples of
Delivering Effective Slide Presenta- tation, including proper font styles, presentations that could benefit from
tions and Posters” as a part of her text sizes, colors, spacing, and other the lessons learned in this seminar.
Scientific Communication Seminar formatting guidelines. Dr. Carver also
Lastly, Dr. Carver provided tips on
Series. Preparing and delivering an provided useful information on pre-
delivering an oral or poster presenta-
oral or poster presentation is more senting conflicts of interest, citing
tion. My personal favorites included
complex than most scientists realize. literature and borrowed materials
using pauses rather than ums & ahs,
In fact, there are subtle details that (e.g., web images), and using a critical
avoiding jargon, and having physical
can substantially improve the clarity yet often overlooked tool, SPELL-
copies of the abstract and/or supple-
and effectiveness of every presenta- CHECK! We also discussed the appro-
mental information in hand.
tion. priate and effective use of images,
including tables, graphs, clip art, and
In this seminar, Dr. Carver discussed
photos. For nearly every point of dis- —C. Pierce Campbell
the general guidelines and essential
5. V o l u m e 2 , I s s u e 1 P a g e 5
U s f p o s t d o c t o r a l r e s e a r c h c o l l o q u i u m
The University of South Florida Post- Allison Cohen (Cancer Imaging & Me- Mailloux (Immunology, PI: P.K. Epling-
doctoral Scholar Association (USF- tabolism, PI: David L. Morse), Yolaine Burnette), and Eva Sahakian
PSA) hosted their 2nd annual Postdoc- Jeune-Smith (Cancer Imaging & Me- (Immunology, PIs: Eduardo M. So-
toral Research Colloquium on Novem- tabolism, PI: David L. Morse), Adam tomayor and Javier Pinella-Ibarz). The
ber 15, 2012 at the USF Marshall Office of Postdoctoral
Student Center. The colloquium Affairs sponsored four
brought together postdoctoral schol- $500 travel awards to
ars in a variety of disciplines from USF, the posters/
USF Health, and Moffitt Cancer Cen- presentations that were
ter. The purpose of the colloquium judged to be the most
was to provide a professional and outstanding by a com-
informal forum for the exchange of mittee of faculty mem-
ideas, research, and practice. Four bers. Kelley Haarberg
applicants were invited by the PSA to was selected as one of
give oral presentations. Kelley Haar- the winners. The other
berg from Xue-Zhong Yu’s group in the winners were Ronan
Department of Immunology was one of Carroll (CMMB), Sandra
the postdocs chosen. Her talk was Acosta (Center for Ag-
entitled “Prevention of Acute Graft- ing), and Neha Woods
Verses-Host Disease through Target- (Molecular Medicine).
ing PKC alpha and theta in Mice”. The Left to right: A. Cohen, E. Sahakian, A. Mailloux, K. Haarberg and
Y. Jeune-Smith
colloquium also featured twenty post-
er presentations. Among the poster —A. Cohen
presenters were four Moffitt postdocs:
M P D A c a r e e r d e v e l o p m e n t l i b r a r y
The Moffitt Postdoc Association has Explaining Research: How to Reach
created a Career Development Sec- Key Audiences to Advance Your Work
tion in the Moffitt Biomedical Library, Author: Dennis Meredith
located on the 1st floor of the MRC
“So What Are You Going to Do with
building. The MPDA has purchased
That?": Finding Careers Outside Aca-
several books, now available to loan
demia
to our postdocs. The selection in-
Author: Susan Basalla and Maggie
cludes:
Debelius
A PhD Is Not Enough!: A Guide to Sur-
Marketing for Scientists – How to
vival in Science
Shine in Tough Times
Author: Peter J. Feibelman
Author: Marc Kuchner, PhD Career and Skill Development Books, located in
Career Opportunities in Biotechnology the Moffitt Biomedical Library, 1st floor MRC.
The Grant Application Writer's Work-
and Drug Development
book - National Institutes of Health
Author: Toby Freedman
Author: Stephen W. Russell and David
Job Search in Academe: Strategic C. Morrison Come visit and check out the full se-
Rhetorics for Faculty Job Candidates lection. If assistance is needed, ask
Author: Formo Dawn M Susan the Librarian.
6. V o l u m e 2 , I s s u e 1 P a g e 6
F e a t u r e d p u b l i c a t i o n s
Christie J Quinn GP, Malo T, Lee JH, Zhao X, McIntyre J, Brzosowicz J, Jacobsen PB and Vadaparampil ST. Cognitive and psycho-
J,
logical impact of BRCA genetic counseling in before and after definitive surgery breast cancer patients. Annals of Surgical On-
cology. 2012 Dec;19(13):4003-4011
Jim HS, Phillips KM Chait S, Faul LA, Popa-McKiver MA, Lee YH, Hussin MG, Jacobsen PB and Small BJ. Meta-analysis of cogni-
KM,
tive functioning in breast cancer survivors previously treated with standard-dose chemotherapy. Journal of Clinical Oncology.
2012 Oct; 30(29):3578-3587
Kang CW Sun Y and Del Valle JR. Substituted Imidazo[1,2-a]pyridines as B-strand peptidomimetics. Organic Letters. 2012 Oct;
CW,
14(24):6162-6165
Kodumudi KN Weber A, Sarnaik AA, Pilon-Thomas S. Blockade of myeloid-derived suppressor cells after induction of lymphope-
KN,
nia improves adoptive T cell therapy in a murine model of melanoma. Journal of Immunology. 2012 Dec; 189(11):5147-5154
Pierce Campbell CM, Menezes LJ, Paskett ED and Giuliano AR. Prevention of invasive cervical cancer in the United States: Past,
CM
present, and future. Cancer Epidemiology Biomarkers & Prevention. 2012 Sep; 21(9):1402-1408
Vadaparampil ST, Malo T, de la Cruz C and Christie J Do breast cancer patients tested in the oncology care setting share BRCA
J.
mutation results with family members and health care providers? Journal of Cancer Epidemiology. 2012 July 15 [Epub ahead
of print] DOI: 10.1155/2012/498062
Vadaparampil ST, Staras SA, Malo TL, Eddleton KZ, Christie J Rodriguez M, Giuliano AR and Shenkman EA. Provider factors
J,
associated with disparities in human papillomavirus vaccination among low-income 9-17-year-old girls. Cancer. 2012 Aug 1.
[Epub ahead of print] DOI: 10.1002/cncr.27735
Wang D, Iclozan C, Liu C, Xia C, Anasetti C and Yu XZ. LBH589 enhances T-cell activation in vivo and accelerates graft-versus-
C
host disease in mice. Biology of Blood and Marrow Transplantion. 2012 Aug; 18(8): 1182-1190.e1
Woods NT Mesquita RD, Sweet M, Carvalho MA, Li X, Liu Y, Nguyen H, Thomas CE, Iversen ES Jr., Marsillac S, Karchin R,
NT,
Koomen J and Monteiro AN. Charting the landscape of tandem BRCT domain–mediated protein interactions. Science Signaling.
2012 Sep; 5(242):rs6
Wu S Chen L, Becker A, Schonbrunn E and Chen J. Casein kinase 1α regulates an MDMX intramolecular interaction to stimu-
S,
late p53 binding. Molecular and Cellular Biology. 2012 Dec; 32(23):4821-4832
Youn JI Kumar V Collazo M, Nefedova Y, Condamine T Cheng C, Villagra A, Antonia S, McCaffrey JC, Fishman M, Sarnaik A,
JI, V, T,
Horna P, Sotomayor E and Gabrilovich DI. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of
myeloid cells in cancer. Nature Immunology. 2012 January 27 [Epub ahead of print] DOI: 10.1038/ni.2526
M P D A s e m i n a r s e r i e s
To give postdocs here at Moffitt an opportunity to practice their presentation skills, the Moffitt Postdoctoral Association has
created a seminar series. Postdocs can sign up to present their research to the Moffitt scientific community during this month-
ly seminar, generally the 3rd Thursday at 4pm. This provides a venue through which you can receive feedback on speaking
skills and to foster collaborations with postdocs from other labs. If you are interested in participating, email Cathy Gaffney
(Cathy.Gaffney@moffitt.org); please be sure to inform your mentor as this will be publicized in MRI Signals and on the electronic
signs throughout Moffitt. This presentation can be added to your CV and included on your annual review in Halogen.
7. IT’S YOUR FUTURE, GET
INVOLVED!!!
H . L E E M O F F I T T
C A N C E R C E N T E R The mission of the Moffitt Postdoctoral Associa-
tion (MPDA) is to foster professional development
Moffitt Postdoctoral Association
12902 Magnolia Drive and social interaction and to provide a collective
MRC 4 voice and liaison between postdoctoral fellows,
Tampa, Fl 33612
faculty and administration.
E-mail: pdaofmcc@moffitt.org
CREDITS: A. Cohen, L. Cook, D. Cress, E. Eksioglu,
C. Gaffney, Y. Jeune-Smith, C. Pierce Campbell,
E. Sahakian and G. Shay
Its your future. Get involved!!!
M p d a c o u n c i l l e a d e r s h i p
w i n t e r / s p r i n g 2 0 1 3
Chair: Leah M. Cook
PhD earned in Molecular and Cellular Pathology from the University of Alabama, Birmingham, AL
Current Lab: Conor Lynch, PhD Tumor Biology/Molecular Oncology
Current Research: One of the focuses of the Lynch Lab is to understand the molecular dynamics of prostate cancer metastasis
to bone. They aim to gain an understanding of mechanisms involved in the progression and survival of metastatic prostate
cancer within bone and are exploring novel therapeutic targets for treating this disease. Leah is currently working with David
Basanta, in the Department of Mathematical Oncology, to explore new methods for targeting prostate cancer metastasis.
Vice Chair: Gemma Shay
PhD earned in Medicine and Therapeutics from the University of Aberdeen, Scotland, UK
Current Lab: Conor Lynch, PhD Tumor Biology/Molecular Oncology
Current Research: Gemma is looking at the roles of MMPs in bone cancer metastasis and making use of novel bone-seeking
MMP-2 inhibitors for the treatment of myeloma
N e w p o s t d o c s o f s u m m e r / f a l l 2 0 1 2
Name Department PI/Lab
Ying Han Immunology Burnette
Arturo Araujo Gutierrez Mathematical Oncology Basanta
Zili Wang Immunology Celis
Michael Emmons Molecular Oncology Hazlehurst
Hua Wang Imaging Gillies
Manali Phadke Molecular Oncology Smalley
Hemachander Subramanian Imaging Gatenby
Jacob Scott Mathematical Oncology Anderson
Yixuan Li Molecular Oncology Seto