SlideShare ist ein Scribd-Unternehmen logo
1 von 75
Downloaden Sie, um offline zu lesen
Fibrin sheath
Atlas of Dialysis Vascular Access
Tushar J. Vachharajani, MD, FASN, FACP
Dedicated to all dialysis patients and hard-working staff
Editorial Assistance - Amanda Goode, MA
Research Programs Development Manager
Department of Internal Medicine
Wake Forest University School of Medicine
Medical Illustration and atlas production
Creative Communications
Wake Forest University School of Medicine
www.wfubmc.edu/creative
Cover design – Vipul Vachharajani
Schematic representation
of arteriovenous fistula
overlapped by a tunneled
central venous catheter
© 2010 by Tushar J. Vachharajani. All rights reserved
ATLAS OF DIALYSIS VASCULAR ACCESS
i
ii
Anatomy of Dialysis Vascular Access ..................................................... 1
Tunneled Catheters ............................................................................. 11
Arteriovenous Fistulas ........................................................................ 26
Arteriovenous Grafts .......................................................................... 51
Glossary ................................................................................................ 65
Bibliography ..................................................................................... 66
TABLE OF CONTENTS
iii
iv
v
I have a passion for improving the basic understanding of the dialysis vascular access. A patient’s survival
depends on proper functioning of this lifeline, yet the dialysis vascular access remains the Achilles’ heel for
hemodialysis patients. Unfortunately, because of the myriad medical problems faced by a patient with renal
failure, the dialysis access gets the least amount of attention.
The current practice of dialysis treatment in the United States depends heavily on an ancillary staff remotely
supervised by a nephrologist. The training curriculum for physicians provides minimal cross-training in
different specialties involved in the creation and maintenance of a dialysis vascular access. Moreover, the
ancillary staffs that provide and supervise the bulk of the care are inadequately trained in the proper handling
of the vascular access.
Diagnostic accuracy and active and timely intervention depend heavily on visual clues that are frequently
missed. There is a need to improve the understanding and visual skills related to the vascular access. The Atlas
of Dialysis Vascular Access is a sincere effort in pursuit of this goal. “A picture is worth a thousand words” - a
common adage that can be aptly used to describe this bedside tool for education. Images express a concept
faster and with greater impact than do pages of textbooks or hours of lectures. This atlas highlights the basic
anatomy of the most frequently used vascular accesses and their associated problems. The images have been
collected from patients who have endured the problems and have graciously consented to be photographed.
The primary intended audiences for the atlas are physicians involved in dialysis vascular access management,
physician extenders, dialysis nurses, patient care technicians, medical students and residents, and clinical
educators involved in training the future generation of dialysis care providers. I hope that this atlas will
ultimately lead towards improved quality of vascular access care.
I would like to thank the Dialysis Access Group of Wake Forest University School of Medicine (www.dagwfu.com)
and its staff (Jean Jordan, RN, Tina Kaufman, RN, Sherry Crawford, RN, Leann Hooker, RN, Wendy Mundy, LPN,
Joyce Jackson, PCT, Margaret Bordner, RT-R and Andrea Roark, RT-R) for their assistance with this project. I am
grateful to Health Systems Management, Inc. for providing me with the basic resources needed to collect the
pictures. And lastly, I would like to thank my son, Vipul Vachharajani, who spent his valuable high school vacation
time to help me with the cover design and with the atlas layout.
Tushar J. Vachharajani, MD, FACP, FASN
Dialysis Access Group of Wake Forest University School of Medicine
PREFACE
vi
ANATOMY OF DIALYSIS VASCULAR ACCESS
1
•	 A basic understanding of the anatomy of vessels utilized to create the vascular access is
crucial for proper handling and care of an access during dialysis therapy.
•	 The venous system of an extremity includes superficial and deep veins. The superficial
system is most important for access creation.
•	 The superficial vein in the upper extremity that is preferred and most commonly utilized
for arteriovenous fistula creation is the cephalic vein.
•	 The radiocephalic arteriovenous fistula at the wrist is the first choice hemodialysis access
and utilizes the forearm segment of the cephalic vein.
•	 The brachiocephalic fistula at the elbow utilizes the upper arm segment of the cephalic
vein and generally is the second choice site for arteriovenous fistula creation.
•	 The other superficial veins in the forearm (the basilic vein on the ulnar side and the median
basilic vein near the elbow) are occasionally used for arteriovenous fistula creation.
•	 The deep veins in the forearm are not ideal for arteriovenous fistula creation. The deep veins
in the upper arm are the brachial and basilic veins that run parallel to the brachial artery.
•	 The basilic vein in the medial aspect of the upper arm is the most common deep vein
utilized for arteriovenous fistula creation. The basilic vein is mobilized from its usual
location and transposed superficially through the deep fascia in the upper arm to create
the “transposed basilic vein” arteriovenous fistula.
•	 The brachial veins in the upper arm are used for dialysis access as a last resort. The brachial
veins and the basilic vein join and continue as the axillary vein until the outer border of the
first rib. The axillary vein continues as subclavian vein from the outer border of the first rib
and extends to the sternal end of the clavicle.
•	 A graft made from synthetic material like polytetrafluoroethylene (PTFE) is utilized for
dialysis access creation if the native vessels are not suitable for creating an arteriovenous
fistula. The forearm loop, upper arm straight and thigh loop grafts are commonly utilized
configurations for creating a dialysis access.
Brachial a.
BICEPS
DELTOID
Cephalic arch
segment
Upper arm
cephalic v.
Forearm
cephalic v.
Radial a.
Palmar arch
Ulnar a.
Basilic v.
Brachial v.
Axillary v.
Subclavian v.
Carotid a.
Internal jugular v.
2
Anatomy of Upper Extremity Vessels
3
Radiocephalic Arteriovenous Fistula (Brescia-Cimino)
 
4
Snuff-box Arteriovenous Fistula
5
Brachiocephalic Arteriovenous Fistula
6
Transposed Basilic Vein Arteriovenous Fistula
Inset: “swing point”
depicting the basilic
vein mobilization from
the deeper location to
the superficial tunnel
7
Forearm Loop Arteriovenous Graft
8
Upper Arm Arteriovenous Graft
9
Thigh Arteriovenous Graft
10
The catheter is placed in
the right internal jugular
vein with a smooth curve in
the subcutaneous tunnel.
The tip of the catheter is
placed in the right atrium
to achieve adequate blood
flow during hemodialysis.
11
Tunneled central vein catheters are often used as temporary accesses for hemodialysis. Tunneled
catheters can be placed at several sites. The preferred site is the right internal jugular vein.
Other sites often used are the left internal jugular vein and femoral vein. Subclavian vein is
accessed only if the possibility of placing an ipsilateral permanent arteriovenous access in the
upper extremity is unavailable. The risk of developing central vein stenosis is very high with a
subclavian vein catheter.
Rarely, tunneled catheters are placed in the inferior vena cava through a translumbar or
transhepatic approach.
Potential complications of a tunneled catheter are:
•	 Malfunction due to mechanical causes like
	 – Poor placement technique
	 – Retraction with or without exposure of the cuff
	 – Cracked hub or broken clamps
	 – Thrombosis/Fibrin sheath formation
•	 Infection
	 – Exit site
	 – Tunnel infection
•	 Central vein stenosis
Early recognition of these complications is important to prevent:
•	 Loss of the vascular site if the catheter falls out
•	 Inadequate dialysis clearance
•	 Bacteremia- and sepsis-related morbidity and mortality
The photographs in this chapter provide adequate tools to enable dialysis access physicians
and staff to recognize and identify common problems associated with tunneled catheters.
TUNNELED CATHETERS
12
Left-sided Catheter
Actual left internal jugular vein
tunneled catheter removed
from a patient showing multiple
angulations along its course.
The complex anatomical path-
way traversed by left internal
jugular vein catheters may be
responsible for higher inci-
dence of catheter malfunction
and thrombosis.
B: Schematic representation of
the additional angulation,
as the catheter traverses
mediastinum and is not vi-
sualized on frontal projec-
tion radiograph.
A: Schematic representation of
the angulations caused by
the left internal jugular vein,
left brachiocephalic vein
and superior vena cava.
A B
Computer generated figures designed by Vipul Vachharajani
13
Right-sided Catheter
Computer generated figures designed by Vipul Vachharajani
Actual right internal jugular vein
tunneled catheter removed from
a patient showing a single smooth
curve.
A: Schematic representation of the
smooth curve
B: Cross-sectional schematic repre-
sentation of the smooth curve
A B
14
Kinked Catheter
The catheter in the
subcutaneous tunnel is
acutely kinked causing
mechanical obstruction
to the blood flow.
15
Malpositioned Tip of Catheter
Left internal jugular
catheter with kink in the
subcutaneous tunnel (ar-
row). The tip is placed
in the left innominate
(brachiocephalic) vein.
The catheter is unlikely
to provide adequate
blood flows for dialysis.
Catheter tip
16
Malpositioned Tip of Catheter
Tesio catheter with malpositioned
tips. Catheter tips are in the proxi-
mal superior vena cava.
Catheter tip
Catheter tip
17
Catheter Tip Retraction
The catheter tip often retracts from a supine to an erect position, especially if it is anchored on
breast or pectoral fat. Thus, the tip of the catheter should be placed in the right atrium.
7th rib 7th rib
18
Catheter Tip in Azygos Vein
A: The tip of the left internal jugular cath-
eter is placed in the azygos vein. An
acute angle curve is noted with twist-
ing of the catheter at the junction of the
superior vena cava and azygos vein.
B: The catheter tip has been repositioned in
the right atrium.
Catheter
tip
A B
19
Fibrin Sheath Formation
Fibrin sheath develops around the catheter. The sheath acts like a one-way valve and prevents
adequate and free pulling of blood through the catheter. The fibrin sheath can be disrupted
either with an angioplasty or can be stripped using a snare device. The pre-angioplasty image
above (A) shows poor filling of the right atrium and the contour of the catheter is maintained
beyond the catheter tip. Post-angioplasty image above (B) shows the contrast flowing freely
in to right atrium. The fibrin sheath can extend from the cuff to beyond the catheter tip.
A B
20
Fibrin sheath
An intact fibrin sheath pulled
out along with the catheter.
A fibrin sheath is a flimsy
fibroepithelial tissue that
extends from the cuff (A) to
the tip of the catheter (B).
A
B
21
Intraluminal Thrombus
Fibrin sheath extending
beyond the tip of the
catheter and occluding it
completely.
An organized thrombus
occluding the tip of the
catheter.
The organized clot ex-
truded from the catheter.
A
B
C
22
Split Tip catheter
A split tip tunneled cath-
eter placed in the left in-
ternal jugular vein. The
arterial tip is curled up
(arrowheads) and kinked
leading to high dialysis
arterial pressures and
poor delivery of blood
flow during dialysis.
 
 
23
Exposed Cuff
A: The cuff of the catheter is exposed
at the exit site. The exit site should
be evaluated prior to each dialy-
sis session. A catheter with an ex-
posed cuff can be easily pulled
out and can lead to loss of a vital
vascular access site. The exposed
catheter cuff would also suggest
that the tip is no longer at the
proper location and delivery of
blood through this catheter may
not be adequate. The replace-
ment of the catheter over a guide
wire can be easily performed with
proper anchoring and the patient
can return for dialysis therapy on
the same day.
B: Disrupted subcutaneous tunnel
(arrowheads) with exposed cath-
eter cuff at the exit site.
A
B
24
Exit Site Infection
Exit site erythema with crusting
suggestive of infection or allergic
reaction to topical ointment or
tape. The exit site should be
evaluated prior to every dialysis
therapyforearlysignsofinfection.
The exit site infection can spread
through the subcutaneous tunnel
causing bacteremia, sepsis and
worsening morbidity and mortality.
25
Tunnel Infection
A: Purulent fluid collection under the
dressing suggestive of infection .
B: Purulent secretion, erythema over the
tunnel and skin changes secondary to
infection in the subcutaneous tunnel.
	 The catheter must be removed promptly
for effective antibiotic therapy and mor-
bidity reduction.
A
B
26
Arteriovenous fistula (AVF) is the preferred dialysis access because of a lower incidence
of associated morbidity and mortality. An AVF is surgically created by connecting the
artery and vein. Approximately 8-12 weeks are required for an AVF to mature completely.
The sites available for creating an AVF are limited, requiring proper handling and care
during hemodialysis therapy.
The common problems associated with an AVF are:
•	 Poor or delayed maturation
•	 Infiltration and hematoma formation during hemodialysis secondary to improper
cannulation technique
•	 Stenosis at the “swing site”, the segment of the vein mobilized for arterial anastomosis
in the creation of an arteriovenous fistula
•	 Stenosis due to neo-intimal hyperplasia, eventually leading to thrombosis
•	 Aneurysmal dilatation either due to vessel trauma from frequent needle punctures
and/or a proximal stenosis
•	 Infection
•	 Steal syndrome due to ischemia of the distal extremity
•	 Central vein stenosis
Many of these problems can be prevented with proper cannulation techniques and
regular monitoring and surveillance during hemodialysis therapy. Early diagnosis and
timely referral requires understanding and recognizing the pathology.
ARTERIOVENOUS FISTULA
The current chapter provides visual aids to commonly seen pathology related to
arteriovenous fistulas and some of the endovascular interventions that can help maintain
their patency. The chapter opens with photographs showing normal vasculature suitable
for creating an AVF. Ideally, an AVF should be created early enough to allow the AVF
to mature and avoid the need to place a central venous catheter for dialysis therapy.
The preservation of vessels in chronic kidney disease patients is the key to creating a
functional AVF.
The remaining images highlight some of the common problems encountered in a busy
hemodialysis clinic.
27
28
Well-preserved Forearm Veins
Well-preserved veins in the forearm and upper arm for creating a functional arte-
riovenous fistula. Vessel preservation is essential in chronic kidney disease patients.
29
Well-preserved Upper Arm Cephalic Vein
Avoiding venipuncture in the forearm and elbow and refraining from placing pe-
ripherally introduced central catheters (PICC) are two methods to preserve veins.
30
Snuff-box AVF
The anastomosis is generally distal to the wrist joint in the snuff-box.
31
Radiocephalic AVF
A normal radiocephalic fistula with the anastomosis proximal to the wrist joint.
32
Transposed Forearm Basilic Vein AVF
The forearm basilic vein is
transposed to create a radio-
basilic vein AVF.
The forearm basilic vein (marked
by arrows) is transposed to the
volar surface of the forearm and
anastomosed to the radial artery
at the wrist.
33
Transposed Forearm Cephalic Vein AVF
The forearm cephalic vein (marked by arrows) is transposed to create a loop configuration
and anastomosed to the brachial artery at the elbow.
34
Brachiocephalic AVF
A normal brachiocephalic fistula
with a horizontal scar at the elbow.
35
Transposed Basilic Vein AVF
A normal transposed basilic vein
arteriovenous fistula showing
the scar extending from the
axilla to the elbow on the medial
aspect of the upper arm.
36
Massive Infiltration
Eighty-year-old patient who had
a functioning right brachioce-
phalic fistula placed well before
the need for dialysis. Unfortu-
nately during his first treatment
the fistula infiltrated due to im-
proper cannulation technique
resulting in a large hematoma
almost encircling his upper arm.
Fortunately for the patient the
fistula was still functional and af-
ter 4 weeks of rest to the arm
the hematoma resolved com-
pletely and the access could be
used for dialysis.
37
Complication of PICC Line
A fistulogram performed on a
non-maturing brachiocephalic
fistula. The entire cephalic vein
segment in the upper arm was
small and sclerosed secondary
to a previous placement of a
peripherally introduced central
catheter (PICC). The devastat-
ing results of a PICC line can be
clearly appreciated in this case.
38
“Swing site” Stenosis
The fistulogram showing a long inflow segment stenosis which was successfully balloon
angioplastied. A: Pre-angioplasty. B: Waist on the balloon. C: Post-angioplasty image.
Thirty-five-year-old patient with a forearm basilic vein to radial artery fistula. The forearm
basilic vein was mobilized surgically leading to significant stenosis in the “swing site”.
The patient presented with inability to achieve prescribed blood flows during dialysis and
with high dialysis arterial pressures. On physical examination the inflow augmentation was
poor with a very weak pulse and bruit.
BA C
Wrist
Radial
artery
Stenosed
forearm
basilic vein
39
A:TransposedbasilicveinAVFwithatightstenosisatthe“swingsite”(arrowhead).B:Waiston
the balloon shown during percutaneous angioplasty. C: Complete resolution of the stenosis.
D: Recurrence of the stenosis 4 months later.
A “swing site” stenosis typically presents as a highly pulsatile fistula with a high pitched bruit
on physical examination. The dialysis venous pressures are recorded to be high and often the
patient continues to bleed for a prolonged period of time once the needle is withdrawn post
dialysis therapy.
BA C D
40
Aneurysm
Brachiocephalic fistula with an
aneurysm at the arterial anas-
tomotic site. The aneurysm has
a tight, shiny skin. The patient
needs to be referred for an ur-
gent surgical evaluation before
a catastrophic event occurs.
 
 
 
41
Mushroom-shaped Aneurysm
Eighty-six-year-old female with a large
“mushroom”-shaped aneurysm at
the anastomosis in a brachiocephalic
fistula. The aneurysm measures
approximately 8cm x 6cm with a shiny
and tense-appearing superficial skin.
An aneurysm needs to be monitored
on a regular basis to avoid reaching
a size as seen in this patient. As per
K/DOQI guidelines the patient with
an aneurysm 1.5 to 2 times the native
vein should be referred for surgical
evaluation and monitored at frequent
intervals for any changes.
A B C
 
 
 
42
Steal syndrome
Eighty-seven-year-old female with a
brachiocephalic fistula created ap-
proximately 9 months prior to pho-
tograph who complained of pain
and numbness over her right hand
during dialysis. On examination the
fingerswereblueandcold(A).PanelB
compares the color of her hand to a
normal pink color.
Upper arm fistulae are more like-
ly to cause ischemic symptoms
compared to forearm fistulae. The
presence of poor peripheral vas-
culature secondary to diabetes,
calcification and peripheral arterial
disease is the primary etiological
factor. A salvage surgical procedure
can sometimes be attempted. This
patient had extensive peripheral
arterial disease requiring ligation of
thefistulatopreservedistalcirculation.
A
B
43
Hematoma
Sixty-one-year-old female with a
recently placed left radiocephalic
fistula, developed a large hematoma
7 days after the surgery. Patients
with chronic kidney disease have
an increased tendency to bleed,
especiallyiftheyaretakingadditional
anti-platelet agents such as aspirin
or clopidrogel or are being anti-
coagulated with warfarin.
Development of a large hematoma
andeasybruisingisfrequentlyobserved
in the dialysis population.
B C
44
Hematoma 
 
Seventy-three-year-old female
patient with a recent surgical
revision of brachiocephalic fis-
tula presented with an acute
golf ball sized hematoma and a
slow leaking pseudoaneurysm.
The steristrips were partially
supporting the gaping surgi-
cal wound. The patient was re-
ferred to the vascular surgeon
for emergent ligation.
45
Central Vein Stenosis
Sixty-seven-year-old man who pre-
sented with left upper arm swell-
ing. He had a transposed basilic
veinfistulaplacedabout18months
prior to photograph. He also had
a history of several central venous
catheters. On examination, he had
prominent collateral veins on his
shoulder and chest wall (Panel A).
The forearm and hand were swol-
len significantly (B).
A fistulogram revealed a 70% ste-
nosis at the “swing site” and 80%
stenosis in the left subclavian vein
accounting for the collateral veins
on the chest wall. The patient was
treated successfully with percuta-
neous angioplasty.
CA
B
46
Skin Rash
Forty-five-year-old male who recently started hemodialysis developed an
allergic reaction to betadine. The rash as seen above was erythematous
and maculo-papular in nature. The patient complained of severe itching
and required therapy with anti-histaminic medications.
Allergic reaction to betadine, iodine, antibiotic cream and tape are not
uncommon and need to be well documented in the patient’s chart for
future reference.
47
Stable Aneurysm
Thirty-six-year-old man with a right brachiocephalic fistula created in
2004. The fistula has several small aneurysms which have been stable.
The overlying skin is intact without any change in pigmentation. The
fistula did not have any evidence of outflow obstruction on physical
examination. A central vein stenosis was ruled out on fistulogram. The
fistula needs to be monitored and patient was educated to inform about
any increase in size or skin changes. The fistula size should be measured
and documented in the medical records for future reference.
C
48
Arm Elevation Test
Seventy-four-year-old male with a radiocephalic fistula
created in 2007. Panel A shows the fullness (arrow)
near the anastomosis due a small aneurysm.
The fullness collapses completely on arm elevation
(Panel B, arrow) suggesting an absence of significant
outflow obstruction. A simple bedside examination that
needs to be performed prior to every dialysis session.
A B
49
Red Hand Syndrome
Twenty-four-year-old male with a radiocephalic fistula that was created
in 2007. The patient presented after having noticed increased swelling,
warmth and difficulty cannulating during dialysis. On examination the
forearm and hand were swollen and erythematous. A bruit was heard
distal to the fistula. The patient was treated with antibiotics for cellulitis.
The arm remained swollen even after the resolution of cellulitis.
A fistulogram revealed multiple collateral veins without any significant
outflow stenosis with increased distal blood flow causing “red hand”
syndrome from venous stasis. The patient was sent for surgical ligation
of multiple collateral veins, which resulted in complete resolution of his
symptoms. The fistula was salvaged.
C
50
Central Vein Stenosis
A: Massively swollen right upper extremity from com-
pletely occluded right subclavian vein. The transposed
basilic vein arteriovenous fistula is patent.
B: Extensive network of collateral
veins over the right shoulder
and chest area.
A B
51
Arteriovenous grafts (AVG) are used for patients who do not have adequate native veins
for creating a fistula. An AVG is the second best option for hemodialysis.
Several sites are used for AVG placement. Forearm loop AVG is the most common.
Upper arm grafts are generally placed as a straight connection between the brachial
artery and the basilic or axillary vein. A thigh AVG is generally a last resort when all other
options in the upper torso are unavailable due to variety of reasons.
AVG are rarely placed across the chest wall, connecting the axillary artery and axillary
vein or axillary artery and a suitable vein on the opposite site. AVG have also been rarely
connected to the right atrial appendage.
The common problems associated with an AVG are:
•	 Venous anastomotic stenosis from neo-intimal hyperplasia
•	 Development of pseudoaneurysms
•	 Thrombosis
•	 Infection
•	 Central vein stenosis, especially with history of multiple central venous catheters
Using a tourniquet is not required while cannulating a graft but it is absolutely essential
for an AVF.
The current chapter highlights some of the common problems associated with an AVG.
ARTERIOVENOUS GRAFTS
52
Tourniquet Use
Using a tourniquet is an absolute must for an arteriovenous fistula (Panel A), which is not
required for an arteriovenous graft (B).
A B
53
Forearm Loop Arteriovenous Graft
A normal forearm loop arteriovenous graft.
54
Upper Arm AVG
A normal upper arm arteriove-
nous graft.
55
Thigh AVG
Photo courtesy of Jack Work, MD
Femur
A. Arteriogram showing the patent arteriovenous
graft in the thigh.
B. A normal thigh arteriovenous graft being used
for dialysis.
A B
56
Pseudoaneurysm
Developmentofpseudoaneurysms
over time in an arteriovenous graft
is not uncommon. The pseudoa-
neurysms develop at frequently
punctured sites and may worsen in
the presence of proximal stenosis.
The needle puncture sites should
be rotated to minimize this compli-
cation. Smaller pseudoaneurysms
can be treated endovascularly with
a covered stent as along as it does
not compromise the cannulation
segment, as shown in the next
image. Larger pseudoaneurysms
need to be treated surgically.
Pseudoaneurysms tend to develop
clots and can lead to thrombosis
of the access. The risk of bleeding
is higher if the pseudoaneurysm is
cannulated for dialysis.
57
Smaller pseudoaneurysms with
superficial skin changes can be at
an increased risk of rupture and
bleeding. Panel A shows mul-
tiple pseudoaneurysms in a pa-
tient with significant skin chang-
es. Due to multiple medical
problems she was a high risk for
surgical intervention and hence
an endovascular procedure was
performed.
Patient underwent an endovas-
cular procedure involving a de-
ployment of a covered stent (B)
resulting in salvaging the graft
and preventing the pseudoaneu-
rysms from expanding further.
A covered stent is a stent coated
with PTFE-like material making
it suitable for cannulation during
dialysis, if absolutely necessary.
A B
58
Multiple Arteriovenous Grafts
Eighty-six-year-old female with a failed forearm loop AVG (inner loop). A new
AVG was placed successfully, utilizing the same arterial inflow and venous outflow
anastomosis (outer loop). Using a long forearm loop of PTFE can increase the
risk of thrombosis due to increased resistance, but fortunately this patient has
had a functioning access one year after surgery.
59
“Sleeves Up” Examination
“Sleeves Up” Examination for every AVG:
All patients with forearm AVGs should have a routine “sleeves up” examination of
the upper arm as seen in this patient. The upper arm cephalic vein (arrow heads) is
nicely developed and can be utilized for future conversion to a secondary arterio-
venous fistula.
60
Central Vein Stenosis
Forty-five-year-old male with a right forearm loop AVG placed in 2003 has marked
central vein stenosis. The collateral veins are visualized on his shoulder and chest
(arrowheads).
The patient has a right subclavian vein stent with recurrent stenosis as shown in
next image.
61
Central Venogram
A: Intrastent stenosis (arrowhead)
in the right subclavian vein.
B: Waist on the balloon used for
angioplasty.
C: Post-angioplasty complete
resolution of the stenosis.
A B C
62
Venous Outflow Stenosis
Ninety-three-year-old male with a left upper arm straight AVG with classic venous outflow
stenosis. The patient was referred for a fistulogram based on clinical findings of pulsatile
character to AVG and prolonged bleeding (more than 30 min.) following dialysis needle
withdrawal.
An 8 cm long segment of stenosis extending from the graft in to the axillary vein was noted
on fistulogram (arrowheads in Panel A). The stenosis was successfully angioplastied using
an 8 mm balloon without any residual stenosis (B).
A B
63
Pseudoaneurysm
Sixty-five-year-old female patient
presented with left upper arm
AVG with large pseudoaneurysms
measuring 4 cm in diameter. The
aneurysms are close to the arterial
anastomosis and were being
frequently punctured for dialysis
cannulation (arrows).
The AVG in the upper extremity has
a lumen diameter of 0.6cm. The
current recommendation from K/
DOQI is to refer patients for surgical
evaluation if the diameter is 1.5-2
times the normal, i.e. 1.2-1.5 cm.
64
Pseudoaneurysm
A fistulogram of a left upper
arm AVG is shown. The
brachial artery (thin black
arrow) is smooth with a widely
patent arterial anastomosis
(thick black arrow). The AVG
has multiple pseudoaneurysms
(white arrow heads) that
are large and at frequently
punctured sites. A surgical
revision of the graft would be
the best available option.
65
Glossary
AVF - Arteriovenous fistula
AVG - Arteriovenous graft
CVC - Central venous catheter
TCC - Tunneled cuffed catheter (same as CVC)
Fistulogram - A radiological test performed using
	 an iodinated radiocontrast material to evaluate 	
	 the access
PTA - Percutaneous transluminal angioplasty or
	 balloon angioplasty
PTFE - Polytetrafluoroethylene graft , the synthetic 		
	 material used for AVG
tPA - Tissue plasminogen activator a thrombolytic 		
	 agent used for clot lysis
Terminologies used for a central vein catheter:
Venotomy site - The site where the catheter enters 		
	 the vein
Exit site - Site where the catheter exits from the skin
Tunnel - The subcutaneous section of the catheter 		
	 between the venotomy and exit sites
Butterfly - The wing beyond the exit site on the cath-	
	 eter used for anchoring the catheter to the skin
Terminologies used for dialysis access examination:
Inflow or upstream - indicates the arterial side of
	 the access
Outflow or downstream - indicates the venous side 	
	 of the access all the way to the right atrium
Arterial anastomosis - Point where the native vein is 	
	 surgically connected to the feeding artery or 		
	 where the PTFE is connected to the artery
Venous anastomosis - Native fistulae do not have a 		
	 venous anastomosis. The AVG connection to 	
	 the outflow vein is called venous anastomosis
Proximal - Anything towards the heart from a
	 reference point
Distal - Anything away from the heart from a
	 reference point
Bifurcation - Forking of a vein or an artery
Collateral veins - Accessory veins that are prominent 	
	 and may prevent maturation of the fistula
66
•	 Badero, OJ, Salifu, MO, Wasse, H & Work, J: Frequency of swing-segment stenosis in referred dialysis
patients with angiographically documented lesions. Am J Kidney Dis, 51:93-8, 2008.
•	 Balaz, P, Rokosny, S, Klein, D & Adamec, M: Aneurysmorrhaphy is an easy technique for arteriovenous fistula salvage.
J Vasc Access, 9:81-4, 2008.
•	 Barshes, NR, Annambhotla, S, Bechara, C, Kougias, P, Huynh, TT, Dardik, A, Silva, MB, Jr. & Lin, PH: Endovas-
cular repair of hemodialysis graft-related pseudoaneurysm: an alternative treatment strategy in salvaging failing
dialysis access. Vasc Endovascular Surg, 42:228-34, 2008.
•	 Beathard, GA: Catheter thrombosis. Semin Dial, 14:441-5, 2001.
•	 Berman, SS, Gentile, AT, Glickman, MH, Mills, JL, Hurwitz, RL, Westerband, A, Marek, JM, Hunter, GC, McEnroe,
CS, Fogle, MA & Stokes, GK: Distal revascularization-interval ligation for limb salvage and maintenance of dialy-
sis access in ischemic steal syndrome. J Vasc Surg, 26:393-402; discussion 402-4, 1997.
•	 Bourquelot, P, Gaudric, J, Turmel-Rodrigues, L, Franco, G, Van Laere, O & Raynaud, A: Transposition of
radial artery for reduction of excessive high-flow in autogenous arm accesses for hemodialysis. J Vasc
Surg, 49:424-8, 428 e1, 2009.
•	 Cavallaro, G, Taranto, F, Cavallaro, E & Quatra, F: Vascular complications of native arteriovenous fistulas
for hemodialysis: role of microsurgery. Microsurgery, 20:252-4, 2000.
•	 Clark, TW, Cohen, RA, Kwak, A, Markmann, JF, Stavropoulos, SW, Patel, AA, Soulen, MC, Mondschein,
JI, Kobrin, S, Shlansky-Goldberg, RD & Trerotola, SO: Salvage of non-maturing native fistulas by using
angioplasty. Radiology, 242:286-92, 2007.
•	 Faintuch, S & Salazar, GM: Malfunction of dialysis catheters: management of fibrin sheath and related
problems. Tech Vasc Interv Radiol, 11:195-200, 2008.
•	 Hausegger, KA, Tiessenhausen, K, Klimpfinger, M, Raith, J, Hauser, H & Tauss, J: Aneurysms of hemodi-
alysis access grafts: treatment with covered stents: a report of three cases. Cardiovasc Intervent Radiol,
21:334-7, 1998.
•	 Janne d’Othee, B, Tham, JC & Sheiman, RG: Restoration of patency in failing
•	 tunneled hemodialysis catheters: a comparison of catheter exchange, exchange and bal-loon disruption
of the fibrin sheath, and femoral stripping. J Vasc Interv Radiol, 17:1011-5, 2006.
•	 Keeling, AN, Naughton, PA, McGrath, FP, Conlon, PJ & Lee, MJ: Successful endovascular treatment of a
hemodialysis graft pseudoaneurysm by covered stent and direct percutaneous thrombin injection. Semin
Dial, 21:553-6, 2008.
•	 Minion, DJ, Moore, E & Endean, E: Revision using distal inflow: a novel approach to dialysis-associated
steal syndrome. Ann Vasc Surg, 19:625-8, 2005.
Reference
67
•	 Muhm, M, Sunder-Plassmann, G, Apsner, R, Pernerstorfer, T, Rajek, A, Lassnigg, A, Prokesch, R, Derfler,
K & Druml, W: Malposition of central venous catheters. Incidence, management and preventive prac-
tices. Wien Klin Wochenschr, 109:400-5, 1997.
•	 Najibi, S, Bush, RL, Terramani, TT, Chaikof, EL, Gunnoud, AB, Lumsden, AB & Weiss, VJ: Covered stent
exclusion of dialysis access pseudoaneurysms. J Surg Res, 106:15-9, 2002.
•	 Rajan, DK, Bunston, S, Misra, S, Pinto, R & Lok, CE: Dysfunctional autogenous hemodialysis fistulas:
outcomes after angioplasty--are there clinical predictors of patency? Radiology, 232:508-15, 2004.
•	 Rajan, DK, Clark, TW, Patel, NK, Stavropoulos, SW & Simons, ME: Prevalence and treatment of cephalic
arch stenosis in dysfunctional autogenous hemodialysis fistulas. J Vasc In-terv Radiol, 14:567-73, 2003.
•	 Rodriguez, HE, Leon, L, Schalch, P, Labropoulos, N, Borge, M & Kalman, PG: Arteriovenous access:
managing common problems. Perspect Vasc Surg Endovasc Ther, 17:155-66, 2005.
•	 Salik E, Daftary A, Tal MG Three-dimensional anatomy of the left central veins: implications for dialysis
catheter placement. J Vasc Interv Radiol. 2007 Mar;18(3):361-4.
•	 Schon, D & Whittman, D: Managing the complications of long-term tunneled dialysis catheters. Semin
Dial, 16:314-22, 2003.
•	 Silas, AM & Bettmann, MA: Utility of covered stents for revision of aging failing synthetic hemodialysis
grafts: a report of three cases. Cardiovasc Intervent Radiol, 26:550-3, 2003.
•	 Spergel, LM, Ravani, P, Roy-Chaudhury, P, Asif, A & Besarab, A: Surgical salvage of the auto-genous
arteriovenous fistula (AVF). J Nephrol, 20:388-98, 2007.
•	 Suojanen, JN, Brophy, DP & Nasser, I: Thrombus on indwelling central venous catheters: the histopa-
thology of “Fibrin sheaths”. Cardiovasc Intervent Radiol, 23:194-7, 2000.
•	 Tessitore, N, Mansueto, G, Lipari, G, Bedogna, V, Tardivo, S, Baggio, E, Cenzi, D, Carbognin, G, Poli, A
& Lupo, A: Endovascular versus surgical preemptive repair of forearm arteriovenous fistula juxta-anas-
tomotic stenosis: analysis of data collected prospectively from 1999 to 2004. Clin J Am Soc Nephrol,
1:448-54, 2006.
•	 Vernhet, H, Dogas, G & Senac, JP: [Dysfunctioning of central venous catheters: role of the radiologist].
Nephrologie, 22:425-7, 2001.
•	 Wong, JK, Sadler, DJ, McCarthy, M, Saliken, JC, So, CB & Gray, RR: Analysis of early failure of tunneled
hemodialysis catheters. AJR Am J Roentgenol, 179:357-63, 2002.

Weitere ähnliche Inhalte

Was ist angesagt?

Vascular access in hemodialysis chaken 2018
Vascular access in hemodialysis chaken 2018Vascular access in hemodialysis chaken 2018
Vascular access in hemodialysis chaken 2018CHAKEN MANIYAN
 
Vascular access 2019
Vascular access 2019Vascular access 2019
Vascular access 2019FarragBahbah
 
Arteriovenous vascular access complications
Arteriovenous vascular access complicationsArteriovenous vascular access complications
Arteriovenous vascular access complicationsReynel Dan
 
Atlas of dialysis vascular access
Atlas of dialysis vascular accessAtlas of dialysis vascular access
Atlas of dialysis vascular accessGualberto Llanos
 
How to examine AVF in 10 minutes - Dr. Gawad
How to examine AVF in 10 minutes - Dr. GawadHow to examine AVF in 10 minutes - Dr. Gawad
How to examine AVF in 10 minutes - Dr. GawadNephroTube - Dr.Gawad
 
Foreign body removal during cardiac catheterization
Foreign body removal during cardiac catheterizationForeign body removal during cardiac catheterization
Foreign body removal during cardiac catheterizationRamachandra Barik
 
Tunneled catheter insertion
Tunneled catheter insertionTunneled catheter insertion
Tunneled catheter insertionFarragBahbah
 
AVF.ppt by M.Mohan
AVF.ppt by M.MohanAVF.ppt by M.Mohan
AVF.ppt by M.MohanMohan Mandem
 
Vascular access for haemodialysis prof. ahmed halawa
Vascular access for haemodialysis prof. ahmed halawaVascular access for haemodialysis prof. ahmed halawa
Vascular access for haemodialysis prof. ahmed halawaFarragBahbah
 
Central venous lines and their problems
Central venous lines and their problemsCentral venous lines and their problems
Central venous lines and their problemsSunil Agrawal
 
Surgery for avf complication
Surgery for avf complicationSurgery for avf complication
Surgery for avf complicationDicky A Wartono
 
Temporary vascular access for hemodialysis
Temporary vascular access for hemodialysisTemporary vascular access for hemodialysis
Temporary vascular access for hemodialysisIPMS- KMU KPK PAKISTAN
 
Dr osama el minshawy - vascular access complications
Dr osama el minshawy - vascular access complicationsDr osama el minshawy - vascular access complications
Dr osama el minshawy - vascular access complicationsFarragBahbah
 
Vascular access surgery by Dr. Ali Mujtaba
Vascular access surgery by Dr. Ali MujtabaVascular access surgery by Dr. Ali Mujtaba
Vascular access surgery by Dr. Ali MujtabaDr Ali MUJTABA
 
Central venous catheter complications
Central venous catheter complicationsCentral venous catheter complications
Central venous catheter complicationsRanjita Pallavi
 

Was ist angesagt? (20)

Vascular access in hemodialysis chaken 2018
Vascular access in hemodialysis chaken 2018Vascular access in hemodialysis chaken 2018
Vascular access in hemodialysis chaken 2018
 
Vascular access 2019
Vascular access 2019Vascular access 2019
Vascular access 2019
 
Arteriovenous vascular access complications
Arteriovenous vascular access complicationsArteriovenous vascular access complications
Arteriovenous vascular access complications
 
Vascular access
Vascular accessVascular access
Vascular access
 
Atlas of dialysis vascular access
Atlas of dialysis vascular accessAtlas of dialysis vascular access
Atlas of dialysis vascular access
 
Permnent vascular access
Permnent vascular accessPermnent vascular access
Permnent vascular access
 
How to examine AVF in 10 minutes - Dr. Gawad
How to examine AVF in 10 minutes - Dr. GawadHow to examine AVF in 10 minutes - Dr. Gawad
How to examine AVF in 10 minutes - Dr. Gawad
 
Foreign body removal during cardiac catheterization
Foreign body removal during cardiac catheterizationForeign body removal during cardiac catheterization
Foreign body removal during cardiac catheterization
 
Vascular access
Vascular accessVascular access
Vascular access
 
Vascular access
Vascular accessVascular access
Vascular access
 
Tunneled catheter insertion
Tunneled catheter insertionTunneled catheter insertion
Tunneled catheter insertion
 
AVF.ppt by M.Mohan
AVF.ppt by M.MohanAVF.ppt by M.Mohan
AVF.ppt by M.Mohan
 
Femoral site psudeoaneurysm
Femoral site psudeoaneurysmFemoral site psudeoaneurysm
Femoral site psudeoaneurysm
 
Vascular access for haemodialysis prof. ahmed halawa
Vascular access for haemodialysis prof. ahmed halawaVascular access for haemodialysis prof. ahmed halawa
Vascular access for haemodialysis prof. ahmed halawa
 
Central venous lines and their problems
Central venous lines and their problemsCentral venous lines and their problems
Central venous lines and their problems
 
Surgery for avf complication
Surgery for avf complicationSurgery for avf complication
Surgery for avf complication
 
Temporary vascular access for hemodialysis
Temporary vascular access for hemodialysisTemporary vascular access for hemodialysis
Temporary vascular access for hemodialysis
 
Dr osama el minshawy - vascular access complications
Dr osama el minshawy - vascular access complicationsDr osama el minshawy - vascular access complications
Dr osama el minshawy - vascular access complications
 
Vascular access surgery by Dr. Ali Mujtaba
Vascular access surgery by Dr. Ali MujtabaVascular access surgery by Dr. Ali Mujtaba
Vascular access surgery by Dr. Ali Mujtaba
 
Central venous catheter complications
Central venous catheter complicationsCentral venous catheter complications
Central venous catheter complications
 

Andere mochten auch

A v fistula in heamodialysis
A v fistula in heamodialysisA v fistula in heamodialysis
A v fistula in heamodialysisSaeed Al-Shomimi
 
Doppler ultrasound of A-V access for hemodialysis
Doppler ultrasound of A-V access for hemodialysisDoppler ultrasound of A-V access for hemodialysis
Doppler ultrasound of A-V access for hemodialysisSamir Haffar
 
Sensitivity of duplex ultrasound in evaluation of av access with comparison t...
Sensitivity of duplex ultrasound in evaluation of av access with comparison t...Sensitivity of duplex ultrasound in evaluation of av access with comparison t...
Sensitivity of duplex ultrasound in evaluation of av access with comparison t...uvcd
 
Acs0626 Medical Management Of Vascular Disease
Acs0626 Medical Management Of Vascular DiseaseAcs0626 Medical Management Of Vascular Disease
Acs0626 Medical Management Of Vascular Diseasemedbookonline
 
Subclavian steal syndrome
Subclavian  steal syndromeSubclavian  steal syndrome
Subclavian steal syndromePrerana Mishra
 
A New Perspective on Vascular Access
A New Perspective on Vascular AccessA New Perspective on Vascular Access
A New Perspective on Vascular Accessstevechendoc
 
Lowergibleeding2003 100623234811-phpapp01
Lowergibleeding2003 100623234811-phpapp01Lowergibleeding2003 100623234811-phpapp01
Lowergibleeding2003 100623234811-phpapp01Aziza ʚïɞ
 
Poster - STIR vs FAT SAT_1009_2015 (1) (1)
Poster - STIR vs  FAT SAT_1009_2015 (1) (1)Poster - STIR vs  FAT SAT_1009_2015 (1) (1)
Poster - STIR vs FAT SAT_1009_2015 (1) (1)Louise Meincke
 

Andere mochten auch (11)

A v fistula in heamodialysis
A v fistula in heamodialysisA v fistula in heamodialysis
A v fistula in heamodialysis
 
Dialysis basics
Dialysis basicsDialysis basics
Dialysis basics
 
Doppler ultrasound of A-V access for hemodialysis
Doppler ultrasound of A-V access for hemodialysisDoppler ultrasound of A-V access for hemodialysis
Doppler ultrasound of A-V access for hemodialysis
 
Ultrapresenshort
UltrapresenshortUltrapresenshort
Ultrapresenshort
 
Sensitivity of duplex ultrasound in evaluation of av access with comparison t...
Sensitivity of duplex ultrasound in evaluation of av access with comparison t...Sensitivity of duplex ultrasound in evaluation of av access with comparison t...
Sensitivity of duplex ultrasound in evaluation of av access with comparison t...
 
Acs0626 Medical Management Of Vascular Disease
Acs0626 Medical Management Of Vascular DiseaseAcs0626 Medical Management Of Vascular Disease
Acs0626 Medical Management Of Vascular Disease
 
Subclavian steal syndrome
Subclavian  steal syndromeSubclavian  steal syndrome
Subclavian steal syndrome
 
A New Perspective on Vascular Access
A New Perspective on Vascular AccessA New Perspective on Vascular Access
A New Perspective on Vascular Access
 
Lowergibleeding2003 100623234811-phpapp01
Lowergibleeding2003 100623234811-phpapp01Lowergibleeding2003 100623234811-phpapp01
Lowergibleeding2003 100623234811-phpapp01
 
CMV in Organ Transplantation
CMV in Organ TransplantationCMV in Organ Transplantation
CMV in Organ Transplantation
 
Poster - STIR vs FAT SAT_1009_2015 (1) (1)
Poster - STIR vs  FAT SAT_1009_2015 (1) (1)Poster - STIR vs  FAT SAT_1009_2015 (1) (1)
Poster - STIR vs FAT SAT_1009_2015 (1) (1)
 

Ähnlich wie Fibrin sheath formation around tunneled dialysis catheters

Vascular access in neonates small children dr. rasha helmy
Vascular access in neonates  small children dr. rasha helmyVascular access in neonates  small children dr. rasha helmy
Vascular access in neonates small children dr. rasha helmyFarragBahbah
 
Basic Intravenous Therapy 1: Anatomy
Basic  Intravenous  Therapy 1: AnatomyBasic  Intravenous  Therapy 1: Anatomy
Basic Intravenous Therapy 1: AnatomyRonald Magbitang
 
Interventional Radiology in General Surgery.pptx
Interventional Radiology in General Surgery.pptxInterventional Radiology in General Surgery.pptx
Interventional Radiology in General Surgery.pptxPRAGATISHUKLA40
 
Iv cannulation sites
Iv cannulation sitesIv cannulation sites
Iv cannulation sitesMercy Abraham
 
Femoral line
Femoral line Femoral line
Femoral line EM OMSB
 
venous & lymphatic drainage of upper limb
venous & lymphatic drainage of upper limbvenous & lymphatic drainage of upper limb
venous & lymphatic drainage of upper limbIallu Reddy
 
Central line placement
Central line placementCentral line placement
Central line placementNeetiJamwal
 
Hemodialysis procedure dr. mohamed kamal
Hemodialysis procedure   dr. mohamed kamalHemodialysis procedure   dr. mohamed kamal
Hemodialysis procedure dr. mohamed kamalFarragBahbah
 
Haemodialysis fistula doppler
Haemodialysis fistula dopplerHaemodialysis fistula doppler
Haemodialysis fistula dopplerSahroz Khan
 
FEMALE PELVIC APPLIED ANATOMY BY DR SHASHWAT JANI
FEMALE PELVIC APPLIED ANATOMY BY DR SHASHWAT JANIFEMALE PELVIC APPLIED ANATOMY BY DR SHASHWAT JANI
FEMALE PELVIC APPLIED ANATOMY BY DR SHASHWAT JANIDR SHASHWAT JANI
 
Acute Myelopathy- Vascular and Infectious Diseases.pdf
Acute Myelopathy- Vascular and Infectious Diseases.pdfAcute Myelopathy- Vascular and Infectious Diseases.pdf
Acute Myelopathy- Vascular and Infectious Diseases.pdfssuser98b21a
 
Venous drainage of lower limb ppt
Venous drainage of lower limb pptVenous drainage of lower limb ppt
Venous drainage of lower limb pptAditi Ujjawal
 
Venous Doppler upper limb
Venous Doppler upper limb Venous Doppler upper limb
Venous Doppler upper limb Milan Silwal
 
Pmdc step 1 Review of CVS & Respiratory System
Pmdc step 1 Review of CVS & Respiratory SystemPmdc step 1 Review of CVS & Respiratory System
Pmdc step 1 Review of CVS & Respiratory SystemDrSaeed Shafi
 
Vascular Access Part 1: Reducing risk and increasing catheter longevity
Vascular Access Part 1: Reducing risk and increasing catheter longevityVascular Access Part 1: Reducing risk and increasing catheter longevity
Vascular Access Part 1: Reducing risk and increasing catheter longevityCoda Change
 

Ähnlich wie Fibrin sheath formation around tunneled dialysis catheters (20)

Vascular access in neonates small children dr. rasha helmy
Vascular access in neonates  small children dr. rasha helmyVascular access in neonates  small children dr. rasha helmy
Vascular access in neonates small children dr. rasha helmy
 
Basic Intravenous Therapy 1: Anatomy
Basic  Intravenous  Therapy 1: AnatomyBasic  Intravenous  Therapy 1: Anatomy
Basic Intravenous Therapy 1: Anatomy
 
Interventional Radiology in General Surgery.pptx
Interventional Radiology in General Surgery.pptxInterventional Radiology in General Surgery.pptx
Interventional Radiology in General Surgery.pptx
 
Iv cannulation sites
Iv cannulation sitesIv cannulation sites
Iv cannulation sites
 
central line.pptx
central line.pptx central line.pptx
central line.pptx
 
Femoral line
Femoral line Femoral line
Femoral line
 
venous & lymphatic drainage of upper limb
venous & lymphatic drainage of upper limbvenous & lymphatic drainage of upper limb
venous & lymphatic drainage of upper limb
 
Hemodialysis
HemodialysisHemodialysis
Hemodialysis
 
Central line placement
Central line placementCentral line placement
Central line placement
 
Venography
VenographyVenography
Venography
 
Hemodialysis procedure dr. mohamed kamal
Hemodialysis procedure   dr. mohamed kamalHemodialysis procedure   dr. mohamed kamal
Hemodialysis procedure dr. mohamed kamal
 
Haemodialysis fistula doppler
Haemodialysis fistula dopplerHaemodialysis fistula doppler
Haemodialysis fistula doppler
 
FEMALE PELVIC APPLIED ANATOMY BY DR SHASHWAT JANI
FEMALE PELVIC APPLIED ANATOMY BY DR SHASHWAT JANIFEMALE PELVIC APPLIED ANATOMY BY DR SHASHWAT JANI
FEMALE PELVIC APPLIED ANATOMY BY DR SHASHWAT JANI
 
catheters.pptx
catheters.pptxcatheters.pptx
catheters.pptx
 
Acute Myelopathy- Vascular and Infectious Diseases.pdf
Acute Myelopathy- Vascular and Infectious Diseases.pdfAcute Myelopathy- Vascular and Infectious Diseases.pdf
Acute Myelopathy- Vascular and Infectious Diseases.pdf
 
Venous drainage of lower limb ppt
Venous drainage of lower limb pptVenous drainage of lower limb ppt
Venous drainage of lower limb ppt
 
Venous Doppler upper limb
Venous Doppler upper limb Venous Doppler upper limb
Venous Doppler upper limb
 
Pmdc step 1 Review of CVS & Respiratory System
Pmdc step 1 Review of CVS & Respiratory SystemPmdc step 1 Review of CVS & Respiratory System
Pmdc step 1 Review of CVS & Respiratory System
 
14048227.ppt
14048227.ppt14048227.ppt
14048227.ppt
 
Vascular Access Part 1: Reducing risk and increasing catheter longevity
Vascular Access Part 1: Reducing risk and increasing catheter longevityVascular Access Part 1: Reducing risk and increasing catheter longevity
Vascular Access Part 1: Reducing risk and increasing catheter longevity
 

Mehr von Hofstra Northwell School of Medicine

Journal Club: Daily Corticosteroids Reduce Infection-associated Relapses in F...
Journal Club: Daily Corticosteroids Reduce Infection-associated Relapses in F...Journal Club: Daily Corticosteroids Reduce Infection-associated Relapses in F...
Journal Club: Daily Corticosteroids Reduce Infection-associated Relapses in F...Hofstra Northwell School of Medicine
 

Mehr von Hofstra Northwell School of Medicine (20)

Amacing
AmacingAmacing
Amacing
 
Amacing
AmacingAmacing
Amacing
 
TA-TMA
TA-TMATA-TMA
TA-TMA
 
HSCT-TMA
HSCT-TMAHSCT-TMA
HSCT-TMA
 
TA-TMA
TA-TMATA-TMA
TA-TMA
 
TA-TMA
TA-TMATA-TMA
TA-TMA
 
HSCT-TMA
HSCT-TMAHSCT-TMA
HSCT-TMA
 
Acute Kidney Injury in the Cardiac Surgery Patient
Acute Kidney Injury in the Cardiac Surgery PatientAcute Kidney Injury in the Cardiac Surgery Patient
Acute Kidney Injury in the Cardiac Surgery Patient
 
Aki cticu final
Aki cticu finalAki cticu final
Aki cticu final
 
Primary hyperoxaluria and the Kidney
Primary hyperoxaluria and the KidneyPrimary hyperoxaluria and the Kidney
Primary hyperoxaluria and the Kidney
 
Obesity paradox
Obesity paradoxObesity paradox
Obesity paradox
 
Journal Club:Stem cells and Kidney Transplantation
Journal Club:Stem cells and Kidney TransplantationJournal Club:Stem cells and Kidney Transplantation
Journal Club:Stem cells and Kidney Transplantation
 
Proteinuria, A medical student prespective
Proteinuria, A medical student prespectiveProteinuria, A medical student prespective
Proteinuria, A medical student prespective
 
Journal Club:SuPAR and FSGS
Journal Club:SuPAR and FSGSJournal Club:SuPAR and FSGS
Journal Club:SuPAR and FSGS
 
FGF-23 and Mortality in Dialysis patients- Journal Club
FGF-23 and Mortality in Dialysis patients- Journal ClubFGF-23 and Mortality in Dialysis patients- Journal Club
FGF-23 and Mortality in Dialysis patients- Journal Club
 
Journal Club: Daily Corticosteroids Reduce Infection-associated Relapses in F...
Journal Club: Daily Corticosteroids Reduce Infection-associated Relapses in F...Journal Club: Daily Corticosteroids Reduce Infection-associated Relapses in F...
Journal Club: Daily Corticosteroids Reduce Infection-associated Relapses in F...
 
Journal Club: Residual renal function
Journal Club: Residual renal functionJournal Club: Residual renal function
Journal Club: Residual renal function
 
Cystic disease of the kidney
Cystic disease of the kidneyCystic disease of the kidney
Cystic disease of the kidney
 
Viruses and the kidney
Viruses and the kidneyViruses and the kidney
Viruses and the kidney
 
Hematuria post transplant
Hematuria post transplantHematuria post transplant
Hematuria post transplant
 

Kürzlich hochgeladen

ENGLISH 7_Q4_LESSON 2_ Employing a Variety of Strategies for Effective Interp...
ENGLISH 7_Q4_LESSON 2_ Employing a Variety of Strategies for Effective Interp...ENGLISH 7_Q4_LESSON 2_ Employing a Variety of Strategies for Effective Interp...
ENGLISH 7_Q4_LESSON 2_ Employing a Variety of Strategies for Effective Interp...JhezDiaz1
 
Keynote by Prof. Wurzer at Nordex about IP-design
Keynote by Prof. Wurzer at Nordex about IP-designKeynote by Prof. Wurzer at Nordex about IP-design
Keynote by Prof. Wurzer at Nordex about IP-designMIPLM
 
Influencing policy (training slides from Fast Track Impact)
Influencing policy (training slides from Fast Track Impact)Influencing policy (training slides from Fast Track Impact)
Influencing policy (training slides from Fast Track Impact)Mark Reed
 
FILIPINO PSYCHology sikolohiyang pilipino
FILIPINO PSYCHology sikolohiyang pilipinoFILIPINO PSYCHology sikolohiyang pilipino
FILIPINO PSYCHology sikolohiyang pilipinojohnmickonozaleda
 
Science 7 Quarter 4 Module 2: Natural Resources.pptx
Science 7 Quarter 4 Module 2: Natural Resources.pptxScience 7 Quarter 4 Module 2: Natural Resources.pptx
Science 7 Quarter 4 Module 2: Natural Resources.pptxMaryGraceBautista27
 
Earth Day Presentation wow hello nice great
Earth Day Presentation wow hello nice greatEarth Day Presentation wow hello nice great
Earth Day Presentation wow hello nice greatYousafMalik24
 
Proudly South Africa powerpoint Thorisha.pptx
Proudly South Africa powerpoint Thorisha.pptxProudly South Africa powerpoint Thorisha.pptx
Proudly South Africa powerpoint Thorisha.pptxthorishapillay1
 
GRADE 4 - SUMMATIVE TEST QUARTER 4 ALL SUBJECTS
GRADE 4 - SUMMATIVE TEST QUARTER 4 ALL SUBJECTSGRADE 4 - SUMMATIVE TEST QUARTER 4 ALL SUBJECTS
GRADE 4 - SUMMATIVE TEST QUARTER 4 ALL SUBJECTSJoshuaGantuangco2
 
Transaction Management in Database Management System
Transaction Management in Database Management SystemTransaction Management in Database Management System
Transaction Management in Database Management SystemChristalin Nelson
 
Procuring digital preservation CAN be quick and painless with our new dynamic...
Procuring digital preservation CAN be quick and painless with our new dynamic...Procuring digital preservation CAN be quick and painless with our new dynamic...
Procuring digital preservation CAN be quick and painless with our new dynamic...Jisc
 
Barangay Council for the Protection of Children (BCPC) Orientation.pptx
Barangay Council for the Protection of Children (BCPC) Orientation.pptxBarangay Council for the Protection of Children (BCPC) Orientation.pptx
Barangay Council for the Protection of Children (BCPC) Orientation.pptxCarlos105
 
Field Attribute Index Feature in Odoo 17
Field Attribute Index Feature in Odoo 17Field Attribute Index Feature in Odoo 17
Field Attribute Index Feature in Odoo 17Celine George
 
THEORIES OF ORGANIZATION-PUBLIC ADMINISTRATION
THEORIES OF ORGANIZATION-PUBLIC ADMINISTRATIONTHEORIES OF ORGANIZATION-PUBLIC ADMINISTRATION
THEORIES OF ORGANIZATION-PUBLIC ADMINISTRATIONHumphrey A Beña
 
USPS® Forced Meter Migration - How to Know if Your Postage Meter Will Soon be...
USPS® Forced Meter Migration - How to Know if Your Postage Meter Will Soon be...USPS® Forced Meter Migration - How to Know if Your Postage Meter Will Soon be...
USPS® Forced Meter Migration - How to Know if Your Postage Meter Will Soon be...Postal Advocate Inc.
 
ENGLISH6-Q4-W3.pptxqurter our high choom
ENGLISH6-Q4-W3.pptxqurter our high choomENGLISH6-Q4-W3.pptxqurter our high choom
ENGLISH6-Q4-W3.pptxqurter our high choomnelietumpap1
 
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdfInclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdfTechSoup
 
Global Lehigh Strategic Initiatives (without descriptions)
Global Lehigh Strategic Initiatives (without descriptions)Global Lehigh Strategic Initiatives (without descriptions)
Global Lehigh Strategic Initiatives (without descriptions)cama23
 

Kürzlich hochgeladen (20)

ENGLISH 7_Q4_LESSON 2_ Employing a Variety of Strategies for Effective Interp...
ENGLISH 7_Q4_LESSON 2_ Employing a Variety of Strategies for Effective Interp...ENGLISH 7_Q4_LESSON 2_ Employing a Variety of Strategies for Effective Interp...
ENGLISH 7_Q4_LESSON 2_ Employing a Variety of Strategies for Effective Interp...
 
YOUVE GOT EMAIL_FINALS_EL_DORADO_2024.pptx
YOUVE GOT EMAIL_FINALS_EL_DORADO_2024.pptxYOUVE GOT EMAIL_FINALS_EL_DORADO_2024.pptx
YOUVE GOT EMAIL_FINALS_EL_DORADO_2024.pptx
 
Keynote by Prof. Wurzer at Nordex about IP-design
Keynote by Prof. Wurzer at Nordex about IP-designKeynote by Prof. Wurzer at Nordex about IP-design
Keynote by Prof. Wurzer at Nordex about IP-design
 
Influencing policy (training slides from Fast Track Impact)
Influencing policy (training slides from Fast Track Impact)Influencing policy (training slides from Fast Track Impact)
Influencing policy (training slides from Fast Track Impact)
 
FILIPINO PSYCHology sikolohiyang pilipino
FILIPINO PSYCHology sikolohiyang pilipinoFILIPINO PSYCHology sikolohiyang pilipino
FILIPINO PSYCHology sikolohiyang pilipino
 
Science 7 Quarter 4 Module 2: Natural Resources.pptx
Science 7 Quarter 4 Module 2: Natural Resources.pptxScience 7 Quarter 4 Module 2: Natural Resources.pptx
Science 7 Quarter 4 Module 2: Natural Resources.pptx
 
Earth Day Presentation wow hello nice great
Earth Day Presentation wow hello nice greatEarth Day Presentation wow hello nice great
Earth Day Presentation wow hello nice great
 
Proudly South Africa powerpoint Thorisha.pptx
Proudly South Africa powerpoint Thorisha.pptxProudly South Africa powerpoint Thorisha.pptx
Proudly South Africa powerpoint Thorisha.pptx
 
LEFT_ON_C'N_ PRELIMS_EL_DORADO_2024.pptx
LEFT_ON_C'N_ PRELIMS_EL_DORADO_2024.pptxLEFT_ON_C'N_ PRELIMS_EL_DORADO_2024.pptx
LEFT_ON_C'N_ PRELIMS_EL_DORADO_2024.pptx
 
GRADE 4 - SUMMATIVE TEST QUARTER 4 ALL SUBJECTS
GRADE 4 - SUMMATIVE TEST QUARTER 4 ALL SUBJECTSGRADE 4 - SUMMATIVE TEST QUARTER 4 ALL SUBJECTS
GRADE 4 - SUMMATIVE TEST QUARTER 4 ALL SUBJECTS
 
Transaction Management in Database Management System
Transaction Management in Database Management SystemTransaction Management in Database Management System
Transaction Management in Database Management System
 
Procuring digital preservation CAN be quick and painless with our new dynamic...
Procuring digital preservation CAN be quick and painless with our new dynamic...Procuring digital preservation CAN be quick and painless with our new dynamic...
Procuring digital preservation CAN be quick and painless with our new dynamic...
 
Barangay Council for the Protection of Children (BCPC) Orientation.pptx
Barangay Council for the Protection of Children (BCPC) Orientation.pptxBarangay Council for the Protection of Children (BCPC) Orientation.pptx
Barangay Council for the Protection of Children (BCPC) Orientation.pptx
 
Field Attribute Index Feature in Odoo 17
Field Attribute Index Feature in Odoo 17Field Attribute Index Feature in Odoo 17
Field Attribute Index Feature in Odoo 17
 
THEORIES OF ORGANIZATION-PUBLIC ADMINISTRATION
THEORIES OF ORGANIZATION-PUBLIC ADMINISTRATIONTHEORIES OF ORGANIZATION-PUBLIC ADMINISTRATION
THEORIES OF ORGANIZATION-PUBLIC ADMINISTRATION
 
USPS® Forced Meter Migration - How to Know if Your Postage Meter Will Soon be...
USPS® Forced Meter Migration - How to Know if Your Postage Meter Will Soon be...USPS® Forced Meter Migration - How to Know if Your Postage Meter Will Soon be...
USPS® Forced Meter Migration - How to Know if Your Postage Meter Will Soon be...
 
ENGLISH6-Q4-W3.pptxqurter our high choom
ENGLISH6-Q4-W3.pptxqurter our high choomENGLISH6-Q4-W3.pptxqurter our high choom
ENGLISH6-Q4-W3.pptxqurter our high choom
 
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdfInclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
 
FINALS_OF_LEFT_ON_C'N_EL_DORADO_2024.pptx
FINALS_OF_LEFT_ON_C'N_EL_DORADO_2024.pptxFINALS_OF_LEFT_ON_C'N_EL_DORADO_2024.pptx
FINALS_OF_LEFT_ON_C'N_EL_DORADO_2024.pptx
 
Global Lehigh Strategic Initiatives (without descriptions)
Global Lehigh Strategic Initiatives (without descriptions)Global Lehigh Strategic Initiatives (without descriptions)
Global Lehigh Strategic Initiatives (without descriptions)
 

Fibrin sheath formation around tunneled dialysis catheters

  • 1. Fibrin sheath Atlas of Dialysis Vascular Access Tushar J. Vachharajani, MD, FASN, FACP
  • 2. Dedicated to all dialysis patients and hard-working staff Editorial Assistance - Amanda Goode, MA Research Programs Development Manager Department of Internal Medicine Wake Forest University School of Medicine Medical Illustration and atlas production Creative Communications Wake Forest University School of Medicine www.wfubmc.edu/creative Cover design – Vipul Vachharajani Schematic representation of arteriovenous fistula overlapped by a tunneled central venous catheter © 2010 by Tushar J. Vachharajani. All rights reserved
  • 3. ATLAS OF DIALYSIS VASCULAR ACCESS i
  • 4. ii
  • 5. Anatomy of Dialysis Vascular Access ..................................................... 1 Tunneled Catheters ............................................................................. 11 Arteriovenous Fistulas ........................................................................ 26 Arteriovenous Grafts .......................................................................... 51 Glossary ................................................................................................ 65 Bibliography ..................................................................................... 66 TABLE OF CONTENTS iii
  • 6. iv
  • 7. v I have a passion for improving the basic understanding of the dialysis vascular access. A patient’s survival depends on proper functioning of this lifeline, yet the dialysis vascular access remains the Achilles’ heel for hemodialysis patients. Unfortunately, because of the myriad medical problems faced by a patient with renal failure, the dialysis access gets the least amount of attention. The current practice of dialysis treatment in the United States depends heavily on an ancillary staff remotely supervised by a nephrologist. The training curriculum for physicians provides minimal cross-training in different specialties involved in the creation and maintenance of a dialysis vascular access. Moreover, the ancillary staffs that provide and supervise the bulk of the care are inadequately trained in the proper handling of the vascular access. Diagnostic accuracy and active and timely intervention depend heavily on visual clues that are frequently missed. There is a need to improve the understanding and visual skills related to the vascular access. The Atlas of Dialysis Vascular Access is a sincere effort in pursuit of this goal. “A picture is worth a thousand words” - a common adage that can be aptly used to describe this bedside tool for education. Images express a concept faster and with greater impact than do pages of textbooks or hours of lectures. This atlas highlights the basic anatomy of the most frequently used vascular accesses and their associated problems. The images have been collected from patients who have endured the problems and have graciously consented to be photographed. The primary intended audiences for the atlas are physicians involved in dialysis vascular access management, physician extenders, dialysis nurses, patient care technicians, medical students and residents, and clinical educators involved in training the future generation of dialysis care providers. I hope that this atlas will ultimately lead towards improved quality of vascular access care. I would like to thank the Dialysis Access Group of Wake Forest University School of Medicine (www.dagwfu.com) and its staff (Jean Jordan, RN, Tina Kaufman, RN, Sherry Crawford, RN, Leann Hooker, RN, Wendy Mundy, LPN, Joyce Jackson, PCT, Margaret Bordner, RT-R and Andrea Roark, RT-R) for their assistance with this project. I am grateful to Health Systems Management, Inc. for providing me with the basic resources needed to collect the pictures. And lastly, I would like to thank my son, Vipul Vachharajani, who spent his valuable high school vacation time to help me with the cover design and with the atlas layout. Tushar J. Vachharajani, MD, FACP, FASN Dialysis Access Group of Wake Forest University School of Medicine PREFACE
  • 8. vi
  • 9. ANATOMY OF DIALYSIS VASCULAR ACCESS 1 • A basic understanding of the anatomy of vessels utilized to create the vascular access is crucial for proper handling and care of an access during dialysis therapy. • The venous system of an extremity includes superficial and deep veins. The superficial system is most important for access creation. • The superficial vein in the upper extremity that is preferred and most commonly utilized for arteriovenous fistula creation is the cephalic vein. • The radiocephalic arteriovenous fistula at the wrist is the first choice hemodialysis access and utilizes the forearm segment of the cephalic vein. • The brachiocephalic fistula at the elbow utilizes the upper arm segment of the cephalic vein and generally is the second choice site for arteriovenous fistula creation. • The other superficial veins in the forearm (the basilic vein on the ulnar side and the median basilic vein near the elbow) are occasionally used for arteriovenous fistula creation. • The deep veins in the forearm are not ideal for arteriovenous fistula creation. The deep veins in the upper arm are the brachial and basilic veins that run parallel to the brachial artery. • The basilic vein in the medial aspect of the upper arm is the most common deep vein utilized for arteriovenous fistula creation. The basilic vein is mobilized from its usual location and transposed superficially through the deep fascia in the upper arm to create the “transposed basilic vein” arteriovenous fistula. • The brachial veins in the upper arm are used for dialysis access as a last resort. The brachial veins and the basilic vein join and continue as the axillary vein until the outer border of the first rib. The axillary vein continues as subclavian vein from the outer border of the first rib and extends to the sternal end of the clavicle. • A graft made from synthetic material like polytetrafluoroethylene (PTFE) is utilized for dialysis access creation if the native vessels are not suitable for creating an arteriovenous fistula. The forearm loop, upper arm straight and thigh loop grafts are commonly utilized configurations for creating a dialysis access.
  • 10. Brachial a. BICEPS DELTOID Cephalic arch segment Upper arm cephalic v. Forearm cephalic v. Radial a. Palmar arch Ulnar a. Basilic v. Brachial v. Axillary v. Subclavian v. Carotid a. Internal jugular v. 2 Anatomy of Upper Extremity Vessels
  • 14. 6 Transposed Basilic Vein Arteriovenous Fistula Inset: “swing point” depicting the basilic vein mobilization from the deeper location to the superficial tunnel
  • 18. 10 The catheter is placed in the right internal jugular vein with a smooth curve in the subcutaneous tunnel. The tip of the catheter is placed in the right atrium to achieve adequate blood flow during hemodialysis.
  • 19. 11 Tunneled central vein catheters are often used as temporary accesses for hemodialysis. Tunneled catheters can be placed at several sites. The preferred site is the right internal jugular vein. Other sites often used are the left internal jugular vein and femoral vein. Subclavian vein is accessed only if the possibility of placing an ipsilateral permanent arteriovenous access in the upper extremity is unavailable. The risk of developing central vein stenosis is very high with a subclavian vein catheter. Rarely, tunneled catheters are placed in the inferior vena cava through a translumbar or transhepatic approach. Potential complications of a tunneled catheter are: • Malfunction due to mechanical causes like – Poor placement technique – Retraction with or without exposure of the cuff – Cracked hub or broken clamps – Thrombosis/Fibrin sheath formation • Infection – Exit site – Tunnel infection • Central vein stenosis Early recognition of these complications is important to prevent: • Loss of the vascular site if the catheter falls out • Inadequate dialysis clearance • Bacteremia- and sepsis-related morbidity and mortality The photographs in this chapter provide adequate tools to enable dialysis access physicians and staff to recognize and identify common problems associated with tunneled catheters. TUNNELED CATHETERS
  • 20. 12 Left-sided Catheter Actual left internal jugular vein tunneled catheter removed from a patient showing multiple angulations along its course. The complex anatomical path- way traversed by left internal jugular vein catheters may be responsible for higher inci- dence of catheter malfunction and thrombosis. B: Schematic representation of the additional angulation, as the catheter traverses mediastinum and is not vi- sualized on frontal projec- tion radiograph. A: Schematic representation of the angulations caused by the left internal jugular vein, left brachiocephalic vein and superior vena cava. A B Computer generated figures designed by Vipul Vachharajani
  • 21. 13 Right-sided Catheter Computer generated figures designed by Vipul Vachharajani Actual right internal jugular vein tunneled catheter removed from a patient showing a single smooth curve. A: Schematic representation of the smooth curve B: Cross-sectional schematic repre- sentation of the smooth curve A B
  • 22. 14 Kinked Catheter The catheter in the subcutaneous tunnel is acutely kinked causing mechanical obstruction to the blood flow.
  • 23. 15 Malpositioned Tip of Catheter Left internal jugular catheter with kink in the subcutaneous tunnel (ar- row). The tip is placed in the left innominate (brachiocephalic) vein. The catheter is unlikely to provide adequate blood flows for dialysis. Catheter tip
  • 24. 16 Malpositioned Tip of Catheter Tesio catheter with malpositioned tips. Catheter tips are in the proxi- mal superior vena cava. Catheter tip Catheter tip
  • 25. 17 Catheter Tip Retraction The catheter tip often retracts from a supine to an erect position, especially if it is anchored on breast or pectoral fat. Thus, the tip of the catheter should be placed in the right atrium. 7th rib 7th rib
  • 26. 18 Catheter Tip in Azygos Vein A: The tip of the left internal jugular cath- eter is placed in the azygos vein. An acute angle curve is noted with twist- ing of the catheter at the junction of the superior vena cava and azygos vein. B: The catheter tip has been repositioned in the right atrium. Catheter tip A B
  • 27. 19 Fibrin Sheath Formation Fibrin sheath develops around the catheter. The sheath acts like a one-way valve and prevents adequate and free pulling of blood through the catheter. The fibrin sheath can be disrupted either with an angioplasty or can be stripped using a snare device. The pre-angioplasty image above (A) shows poor filling of the right atrium and the contour of the catheter is maintained beyond the catheter tip. Post-angioplasty image above (B) shows the contrast flowing freely in to right atrium. The fibrin sheath can extend from the cuff to beyond the catheter tip. A B
  • 28. 20 Fibrin sheath An intact fibrin sheath pulled out along with the catheter. A fibrin sheath is a flimsy fibroepithelial tissue that extends from the cuff (A) to the tip of the catheter (B). A B
  • 29. 21 Intraluminal Thrombus Fibrin sheath extending beyond the tip of the catheter and occluding it completely. An organized thrombus occluding the tip of the catheter. The organized clot ex- truded from the catheter. A B C
  • 30. 22 Split Tip catheter A split tip tunneled cath- eter placed in the left in- ternal jugular vein. The arterial tip is curled up (arrowheads) and kinked leading to high dialysis arterial pressures and poor delivery of blood flow during dialysis.    
  • 31. 23 Exposed Cuff A: The cuff of the catheter is exposed at the exit site. The exit site should be evaluated prior to each dialy- sis session. A catheter with an ex- posed cuff can be easily pulled out and can lead to loss of a vital vascular access site. The exposed catheter cuff would also suggest that the tip is no longer at the proper location and delivery of blood through this catheter may not be adequate. The replace- ment of the catheter over a guide wire can be easily performed with proper anchoring and the patient can return for dialysis therapy on the same day. B: Disrupted subcutaneous tunnel (arrowheads) with exposed cath- eter cuff at the exit site. A B
  • 32. 24 Exit Site Infection Exit site erythema with crusting suggestive of infection or allergic reaction to topical ointment or tape. The exit site should be evaluated prior to every dialysis therapyforearlysignsofinfection. The exit site infection can spread through the subcutaneous tunnel causing bacteremia, sepsis and worsening morbidity and mortality.
  • 33. 25 Tunnel Infection A: Purulent fluid collection under the dressing suggestive of infection . B: Purulent secretion, erythema over the tunnel and skin changes secondary to infection in the subcutaneous tunnel. The catheter must be removed promptly for effective antibiotic therapy and mor- bidity reduction. A B
  • 34. 26 Arteriovenous fistula (AVF) is the preferred dialysis access because of a lower incidence of associated morbidity and mortality. An AVF is surgically created by connecting the artery and vein. Approximately 8-12 weeks are required for an AVF to mature completely. The sites available for creating an AVF are limited, requiring proper handling and care during hemodialysis therapy. The common problems associated with an AVF are: • Poor or delayed maturation • Infiltration and hematoma formation during hemodialysis secondary to improper cannulation technique • Stenosis at the “swing site”, the segment of the vein mobilized for arterial anastomosis in the creation of an arteriovenous fistula • Stenosis due to neo-intimal hyperplasia, eventually leading to thrombosis • Aneurysmal dilatation either due to vessel trauma from frequent needle punctures and/or a proximal stenosis • Infection • Steal syndrome due to ischemia of the distal extremity • Central vein stenosis Many of these problems can be prevented with proper cannulation techniques and regular monitoring and surveillance during hemodialysis therapy. Early diagnosis and timely referral requires understanding and recognizing the pathology. ARTERIOVENOUS FISTULA
  • 35. The current chapter provides visual aids to commonly seen pathology related to arteriovenous fistulas and some of the endovascular interventions that can help maintain their patency. The chapter opens with photographs showing normal vasculature suitable for creating an AVF. Ideally, an AVF should be created early enough to allow the AVF to mature and avoid the need to place a central venous catheter for dialysis therapy. The preservation of vessels in chronic kidney disease patients is the key to creating a functional AVF. The remaining images highlight some of the common problems encountered in a busy hemodialysis clinic. 27
  • 36. 28 Well-preserved Forearm Veins Well-preserved veins in the forearm and upper arm for creating a functional arte- riovenous fistula. Vessel preservation is essential in chronic kidney disease patients.
  • 37. 29 Well-preserved Upper Arm Cephalic Vein Avoiding venipuncture in the forearm and elbow and refraining from placing pe- ripherally introduced central catheters (PICC) are two methods to preserve veins.
  • 38. 30 Snuff-box AVF The anastomosis is generally distal to the wrist joint in the snuff-box.
  • 39. 31 Radiocephalic AVF A normal radiocephalic fistula with the anastomosis proximal to the wrist joint.
  • 40. 32 Transposed Forearm Basilic Vein AVF The forearm basilic vein is transposed to create a radio- basilic vein AVF. The forearm basilic vein (marked by arrows) is transposed to the volar surface of the forearm and anastomosed to the radial artery at the wrist.
  • 41. 33 Transposed Forearm Cephalic Vein AVF The forearm cephalic vein (marked by arrows) is transposed to create a loop configuration and anastomosed to the brachial artery at the elbow.
  • 42. 34 Brachiocephalic AVF A normal brachiocephalic fistula with a horizontal scar at the elbow.
  • 43. 35 Transposed Basilic Vein AVF A normal transposed basilic vein arteriovenous fistula showing the scar extending from the axilla to the elbow on the medial aspect of the upper arm.
  • 44. 36 Massive Infiltration Eighty-year-old patient who had a functioning right brachioce- phalic fistula placed well before the need for dialysis. Unfortu- nately during his first treatment the fistula infiltrated due to im- proper cannulation technique resulting in a large hematoma almost encircling his upper arm. Fortunately for the patient the fistula was still functional and af- ter 4 weeks of rest to the arm the hematoma resolved com- pletely and the access could be used for dialysis.
  • 45. 37 Complication of PICC Line A fistulogram performed on a non-maturing brachiocephalic fistula. The entire cephalic vein segment in the upper arm was small and sclerosed secondary to a previous placement of a peripherally introduced central catheter (PICC). The devastat- ing results of a PICC line can be clearly appreciated in this case.
  • 46. 38 “Swing site” Stenosis The fistulogram showing a long inflow segment stenosis which was successfully balloon angioplastied. A: Pre-angioplasty. B: Waist on the balloon. C: Post-angioplasty image. Thirty-five-year-old patient with a forearm basilic vein to radial artery fistula. The forearm basilic vein was mobilized surgically leading to significant stenosis in the “swing site”. The patient presented with inability to achieve prescribed blood flows during dialysis and with high dialysis arterial pressures. On physical examination the inflow augmentation was poor with a very weak pulse and bruit. BA C Wrist Radial artery Stenosed forearm basilic vein
  • 47. 39 A:TransposedbasilicveinAVFwithatightstenosisatthe“swingsite”(arrowhead).B:Waiston the balloon shown during percutaneous angioplasty. C: Complete resolution of the stenosis. D: Recurrence of the stenosis 4 months later. A “swing site” stenosis typically presents as a highly pulsatile fistula with a high pitched bruit on physical examination. The dialysis venous pressures are recorded to be high and often the patient continues to bleed for a prolonged period of time once the needle is withdrawn post dialysis therapy. BA C D
  • 48. 40 Aneurysm Brachiocephalic fistula with an aneurysm at the arterial anas- tomotic site. The aneurysm has a tight, shiny skin. The patient needs to be referred for an ur- gent surgical evaluation before a catastrophic event occurs.      
  • 49. 41 Mushroom-shaped Aneurysm Eighty-six-year-old female with a large “mushroom”-shaped aneurysm at the anastomosis in a brachiocephalic fistula. The aneurysm measures approximately 8cm x 6cm with a shiny and tense-appearing superficial skin. An aneurysm needs to be monitored on a regular basis to avoid reaching a size as seen in this patient. As per K/DOQI guidelines the patient with an aneurysm 1.5 to 2 times the native vein should be referred for surgical evaluation and monitored at frequent intervals for any changes. A B C      
  • 50. 42 Steal syndrome Eighty-seven-year-old female with a brachiocephalic fistula created ap- proximately 9 months prior to pho- tograph who complained of pain and numbness over her right hand during dialysis. On examination the fingerswereblueandcold(A).PanelB compares the color of her hand to a normal pink color. Upper arm fistulae are more like- ly to cause ischemic symptoms compared to forearm fistulae. The presence of poor peripheral vas- culature secondary to diabetes, calcification and peripheral arterial disease is the primary etiological factor. A salvage surgical procedure can sometimes be attempted. This patient had extensive peripheral arterial disease requiring ligation of thefistulatopreservedistalcirculation. A B
  • 51. 43 Hematoma Sixty-one-year-old female with a recently placed left radiocephalic fistula, developed a large hematoma 7 days after the surgery. Patients with chronic kidney disease have an increased tendency to bleed, especiallyiftheyaretakingadditional anti-platelet agents such as aspirin or clopidrogel or are being anti- coagulated with warfarin. Development of a large hematoma andeasybruisingisfrequentlyobserved in the dialysis population. B C
  • 52. 44 Hematoma    Seventy-three-year-old female patient with a recent surgical revision of brachiocephalic fis- tula presented with an acute golf ball sized hematoma and a slow leaking pseudoaneurysm. The steristrips were partially supporting the gaping surgi- cal wound. The patient was re- ferred to the vascular surgeon for emergent ligation.
  • 53. 45 Central Vein Stenosis Sixty-seven-year-old man who pre- sented with left upper arm swell- ing. He had a transposed basilic veinfistulaplacedabout18months prior to photograph. He also had a history of several central venous catheters. On examination, he had prominent collateral veins on his shoulder and chest wall (Panel A). The forearm and hand were swol- len significantly (B). A fistulogram revealed a 70% ste- nosis at the “swing site” and 80% stenosis in the left subclavian vein accounting for the collateral veins on the chest wall. The patient was treated successfully with percuta- neous angioplasty. CA B
  • 54. 46 Skin Rash Forty-five-year-old male who recently started hemodialysis developed an allergic reaction to betadine. The rash as seen above was erythematous and maculo-papular in nature. The patient complained of severe itching and required therapy with anti-histaminic medications. Allergic reaction to betadine, iodine, antibiotic cream and tape are not uncommon and need to be well documented in the patient’s chart for future reference.
  • 55. 47 Stable Aneurysm Thirty-six-year-old man with a right brachiocephalic fistula created in 2004. The fistula has several small aneurysms which have been stable. The overlying skin is intact without any change in pigmentation. The fistula did not have any evidence of outflow obstruction on physical examination. A central vein stenosis was ruled out on fistulogram. The fistula needs to be monitored and patient was educated to inform about any increase in size or skin changes. The fistula size should be measured and documented in the medical records for future reference. C
  • 56. 48 Arm Elevation Test Seventy-four-year-old male with a radiocephalic fistula created in 2007. Panel A shows the fullness (arrow) near the anastomosis due a small aneurysm. The fullness collapses completely on arm elevation (Panel B, arrow) suggesting an absence of significant outflow obstruction. A simple bedside examination that needs to be performed prior to every dialysis session. A B
  • 57. 49 Red Hand Syndrome Twenty-four-year-old male with a radiocephalic fistula that was created in 2007. The patient presented after having noticed increased swelling, warmth and difficulty cannulating during dialysis. On examination the forearm and hand were swollen and erythematous. A bruit was heard distal to the fistula. The patient was treated with antibiotics for cellulitis. The arm remained swollen even after the resolution of cellulitis. A fistulogram revealed multiple collateral veins without any significant outflow stenosis with increased distal blood flow causing “red hand” syndrome from venous stasis. The patient was sent for surgical ligation of multiple collateral veins, which resulted in complete resolution of his symptoms. The fistula was salvaged. C
  • 58. 50 Central Vein Stenosis A: Massively swollen right upper extremity from com- pletely occluded right subclavian vein. The transposed basilic vein arteriovenous fistula is patent. B: Extensive network of collateral veins over the right shoulder and chest area. A B
  • 59. 51 Arteriovenous grafts (AVG) are used for patients who do not have adequate native veins for creating a fistula. An AVG is the second best option for hemodialysis. Several sites are used for AVG placement. Forearm loop AVG is the most common. Upper arm grafts are generally placed as a straight connection between the brachial artery and the basilic or axillary vein. A thigh AVG is generally a last resort when all other options in the upper torso are unavailable due to variety of reasons. AVG are rarely placed across the chest wall, connecting the axillary artery and axillary vein or axillary artery and a suitable vein on the opposite site. AVG have also been rarely connected to the right atrial appendage. The common problems associated with an AVG are: • Venous anastomotic stenosis from neo-intimal hyperplasia • Development of pseudoaneurysms • Thrombosis • Infection • Central vein stenosis, especially with history of multiple central venous catheters Using a tourniquet is not required while cannulating a graft but it is absolutely essential for an AVF. The current chapter highlights some of the common problems associated with an AVG. ARTERIOVENOUS GRAFTS
  • 60. 52 Tourniquet Use Using a tourniquet is an absolute must for an arteriovenous fistula (Panel A), which is not required for an arteriovenous graft (B). A B
  • 61. 53 Forearm Loop Arteriovenous Graft A normal forearm loop arteriovenous graft.
  • 62. 54 Upper Arm AVG A normal upper arm arteriove- nous graft.
  • 63. 55 Thigh AVG Photo courtesy of Jack Work, MD Femur A. Arteriogram showing the patent arteriovenous graft in the thigh. B. A normal thigh arteriovenous graft being used for dialysis. A B
  • 64. 56 Pseudoaneurysm Developmentofpseudoaneurysms over time in an arteriovenous graft is not uncommon. The pseudoa- neurysms develop at frequently punctured sites and may worsen in the presence of proximal stenosis. The needle puncture sites should be rotated to minimize this compli- cation. Smaller pseudoaneurysms can be treated endovascularly with a covered stent as along as it does not compromise the cannulation segment, as shown in the next image. Larger pseudoaneurysms need to be treated surgically. Pseudoaneurysms tend to develop clots and can lead to thrombosis of the access. The risk of bleeding is higher if the pseudoaneurysm is cannulated for dialysis.
  • 65. 57 Smaller pseudoaneurysms with superficial skin changes can be at an increased risk of rupture and bleeding. Panel A shows mul- tiple pseudoaneurysms in a pa- tient with significant skin chang- es. Due to multiple medical problems she was a high risk for surgical intervention and hence an endovascular procedure was performed. Patient underwent an endovas- cular procedure involving a de- ployment of a covered stent (B) resulting in salvaging the graft and preventing the pseudoaneu- rysms from expanding further. A covered stent is a stent coated with PTFE-like material making it suitable for cannulation during dialysis, if absolutely necessary. A B
  • 66. 58 Multiple Arteriovenous Grafts Eighty-six-year-old female with a failed forearm loop AVG (inner loop). A new AVG was placed successfully, utilizing the same arterial inflow and venous outflow anastomosis (outer loop). Using a long forearm loop of PTFE can increase the risk of thrombosis due to increased resistance, but fortunately this patient has had a functioning access one year after surgery.
  • 67. 59 “Sleeves Up” Examination “Sleeves Up” Examination for every AVG: All patients with forearm AVGs should have a routine “sleeves up” examination of the upper arm as seen in this patient. The upper arm cephalic vein (arrow heads) is nicely developed and can be utilized for future conversion to a secondary arterio- venous fistula.
  • 68. 60 Central Vein Stenosis Forty-five-year-old male with a right forearm loop AVG placed in 2003 has marked central vein stenosis. The collateral veins are visualized on his shoulder and chest (arrowheads). The patient has a right subclavian vein stent with recurrent stenosis as shown in next image.
  • 69. 61 Central Venogram A: Intrastent stenosis (arrowhead) in the right subclavian vein. B: Waist on the balloon used for angioplasty. C: Post-angioplasty complete resolution of the stenosis. A B C
  • 70. 62 Venous Outflow Stenosis Ninety-three-year-old male with a left upper arm straight AVG with classic venous outflow stenosis. The patient was referred for a fistulogram based on clinical findings of pulsatile character to AVG and prolonged bleeding (more than 30 min.) following dialysis needle withdrawal. An 8 cm long segment of stenosis extending from the graft in to the axillary vein was noted on fistulogram (arrowheads in Panel A). The stenosis was successfully angioplastied using an 8 mm balloon without any residual stenosis (B). A B
  • 71. 63 Pseudoaneurysm Sixty-five-year-old female patient presented with left upper arm AVG with large pseudoaneurysms measuring 4 cm in diameter. The aneurysms are close to the arterial anastomosis and were being frequently punctured for dialysis cannulation (arrows). The AVG in the upper extremity has a lumen diameter of 0.6cm. The current recommendation from K/ DOQI is to refer patients for surgical evaluation if the diameter is 1.5-2 times the normal, i.e. 1.2-1.5 cm.
  • 72. 64 Pseudoaneurysm A fistulogram of a left upper arm AVG is shown. The brachial artery (thin black arrow) is smooth with a widely patent arterial anastomosis (thick black arrow). The AVG has multiple pseudoaneurysms (white arrow heads) that are large and at frequently punctured sites. A surgical revision of the graft would be the best available option.
  • 73. 65 Glossary AVF - Arteriovenous fistula AVG - Arteriovenous graft CVC - Central venous catheter TCC - Tunneled cuffed catheter (same as CVC) Fistulogram - A radiological test performed using an iodinated radiocontrast material to evaluate the access PTA - Percutaneous transluminal angioplasty or balloon angioplasty PTFE - Polytetrafluoroethylene graft , the synthetic material used for AVG tPA - Tissue plasminogen activator a thrombolytic agent used for clot lysis Terminologies used for a central vein catheter: Venotomy site - The site where the catheter enters the vein Exit site - Site where the catheter exits from the skin Tunnel - The subcutaneous section of the catheter between the venotomy and exit sites Butterfly - The wing beyond the exit site on the cath- eter used for anchoring the catheter to the skin Terminologies used for dialysis access examination: Inflow or upstream - indicates the arterial side of the access Outflow or downstream - indicates the venous side of the access all the way to the right atrium Arterial anastomosis - Point where the native vein is surgically connected to the feeding artery or where the PTFE is connected to the artery Venous anastomosis - Native fistulae do not have a venous anastomosis. The AVG connection to the outflow vein is called venous anastomosis Proximal - Anything towards the heart from a reference point Distal - Anything away from the heart from a reference point Bifurcation - Forking of a vein or an artery Collateral veins - Accessory veins that are prominent and may prevent maturation of the fistula
  • 74. 66 • Badero, OJ, Salifu, MO, Wasse, H & Work, J: Frequency of swing-segment stenosis in referred dialysis patients with angiographically documented lesions. Am J Kidney Dis, 51:93-8, 2008. • Balaz, P, Rokosny, S, Klein, D & Adamec, M: Aneurysmorrhaphy is an easy technique for arteriovenous fistula salvage. J Vasc Access, 9:81-4, 2008. • Barshes, NR, Annambhotla, S, Bechara, C, Kougias, P, Huynh, TT, Dardik, A, Silva, MB, Jr. & Lin, PH: Endovas- cular repair of hemodialysis graft-related pseudoaneurysm: an alternative treatment strategy in salvaging failing dialysis access. Vasc Endovascular Surg, 42:228-34, 2008. • Beathard, GA: Catheter thrombosis. Semin Dial, 14:441-5, 2001. • Berman, SS, Gentile, AT, Glickman, MH, Mills, JL, Hurwitz, RL, Westerband, A, Marek, JM, Hunter, GC, McEnroe, CS, Fogle, MA & Stokes, GK: Distal revascularization-interval ligation for limb salvage and maintenance of dialy- sis access in ischemic steal syndrome. J Vasc Surg, 26:393-402; discussion 402-4, 1997. • Bourquelot, P, Gaudric, J, Turmel-Rodrigues, L, Franco, G, Van Laere, O & Raynaud, A: Transposition of radial artery for reduction of excessive high-flow in autogenous arm accesses for hemodialysis. J Vasc Surg, 49:424-8, 428 e1, 2009. • Cavallaro, G, Taranto, F, Cavallaro, E & Quatra, F: Vascular complications of native arteriovenous fistulas for hemodialysis: role of microsurgery. Microsurgery, 20:252-4, 2000. • Clark, TW, Cohen, RA, Kwak, A, Markmann, JF, Stavropoulos, SW, Patel, AA, Soulen, MC, Mondschein, JI, Kobrin, S, Shlansky-Goldberg, RD & Trerotola, SO: Salvage of non-maturing native fistulas by using angioplasty. Radiology, 242:286-92, 2007. • Faintuch, S & Salazar, GM: Malfunction of dialysis catheters: management of fibrin sheath and related problems. Tech Vasc Interv Radiol, 11:195-200, 2008. • Hausegger, KA, Tiessenhausen, K, Klimpfinger, M, Raith, J, Hauser, H & Tauss, J: Aneurysms of hemodi- alysis access grafts: treatment with covered stents: a report of three cases. Cardiovasc Intervent Radiol, 21:334-7, 1998. • Janne d’Othee, B, Tham, JC & Sheiman, RG: Restoration of patency in failing • tunneled hemodialysis catheters: a comparison of catheter exchange, exchange and bal-loon disruption of the fibrin sheath, and femoral stripping. J Vasc Interv Radiol, 17:1011-5, 2006. • Keeling, AN, Naughton, PA, McGrath, FP, Conlon, PJ & Lee, MJ: Successful endovascular treatment of a hemodialysis graft pseudoaneurysm by covered stent and direct percutaneous thrombin injection. Semin Dial, 21:553-6, 2008. • Minion, DJ, Moore, E & Endean, E: Revision using distal inflow: a novel approach to dialysis-associated steal syndrome. Ann Vasc Surg, 19:625-8, 2005. Reference
  • 75. 67 • Muhm, M, Sunder-Plassmann, G, Apsner, R, Pernerstorfer, T, Rajek, A, Lassnigg, A, Prokesch, R, Derfler, K & Druml, W: Malposition of central venous catheters. Incidence, management and preventive prac- tices. Wien Klin Wochenschr, 109:400-5, 1997. • Najibi, S, Bush, RL, Terramani, TT, Chaikof, EL, Gunnoud, AB, Lumsden, AB & Weiss, VJ: Covered stent exclusion of dialysis access pseudoaneurysms. J Surg Res, 106:15-9, 2002. • Rajan, DK, Bunston, S, Misra, S, Pinto, R & Lok, CE: Dysfunctional autogenous hemodialysis fistulas: outcomes after angioplasty--are there clinical predictors of patency? Radiology, 232:508-15, 2004. • Rajan, DK, Clark, TW, Patel, NK, Stavropoulos, SW & Simons, ME: Prevalence and treatment of cephalic arch stenosis in dysfunctional autogenous hemodialysis fistulas. J Vasc In-terv Radiol, 14:567-73, 2003. • Rodriguez, HE, Leon, L, Schalch, P, Labropoulos, N, Borge, M & Kalman, PG: Arteriovenous access: managing common problems. Perspect Vasc Surg Endovasc Ther, 17:155-66, 2005. • Salik E, Daftary A, Tal MG Three-dimensional anatomy of the left central veins: implications for dialysis catheter placement. J Vasc Interv Radiol. 2007 Mar;18(3):361-4. • Schon, D & Whittman, D: Managing the complications of long-term tunneled dialysis catheters. Semin Dial, 16:314-22, 2003. • Silas, AM & Bettmann, MA: Utility of covered stents for revision of aging failing synthetic hemodialysis grafts: a report of three cases. Cardiovasc Intervent Radiol, 26:550-3, 2003. • Spergel, LM, Ravani, P, Roy-Chaudhury, P, Asif, A & Besarab, A: Surgical salvage of the auto-genous arteriovenous fistula (AVF). J Nephrol, 20:388-98, 2007. • Suojanen, JN, Brophy, DP & Nasser, I: Thrombus on indwelling central venous catheters: the histopa- thology of “Fibrin sheaths”. Cardiovasc Intervent Radiol, 23:194-7, 2000. • Tessitore, N, Mansueto, G, Lipari, G, Bedogna, V, Tardivo, S, Baggio, E, Cenzi, D, Carbognin, G, Poli, A & Lupo, A: Endovascular versus surgical preemptive repair of forearm arteriovenous fistula juxta-anas- tomotic stenosis: analysis of data collected prospectively from 1999 to 2004. Clin J Am Soc Nephrol, 1:448-54, 2006. • Vernhet, H, Dogas, G & Senac, JP: [Dysfunctioning of central venous catheters: role of the radiologist]. Nephrologie, 22:425-7, 2001. • Wong, JK, Sadler, DJ, McCarthy, M, Saliken, JC, So, CB & Gray, RR: Analysis of early failure of tunneled hemodialysis catheters. AJR Am J Roentgenol, 179:357-63, 2002.