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DRUGS AS A CAUSE OF
          MALNUTRITION
• Mario Wilmath
OBJECTIVES
•   At risk populations
•   Drugs Classes
•   Treatment
•   Prevention
Physical Interactions
• Ca, mg, fe, al, or Zn can lower oral abs of
  levothyroxine and quinolones.
• Tube feedings decrease phyntoin and
  levothyroxine
Appropriate Prescribing
• Established efficacy
• Compatible safety
• Low risk of drug interactions
• Low risk of nutrient interactions
• Known adjustments for disease states or organ
  function
• Convenient
• Affordable
Decreased Drug Effect
• Warfarin and vitamin-K containing foods
Decreased Oral Intake or Appetite
• Meds that alter taste (dysgeusia)
  – Captopril
  – Clarithromycin
• Decrease saliva production (xerostomia)
• Antihistamines, antidepressants,
  antipsychotics, clonidine, diuretics

• Make mastication and swallowing dificult
Nutrient-Drug Interactions
•   Constipation
•   Inadequate or excessive fluid intake
•   Need for a tyramine-restriction.
•    It is advisable to refrain from blaming the
    medication for side effects while working to
    minimize the consequences.
•   Choosing a Nutrient-rich Diet
•    Antioxidants
•   B-Vitamins and Folate
•   Calcium Vitamin D
•   Fiber
•   Iron Magnesium Potassium
SUMMARY
REFERENCES
•   Reuben DB, Herr KA, Pacala JT, et al. Geriatrics at your fingertips: 2009, 11th Editiion. New York: The
    American Geriatrics Society; 2009.

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Nutrition Presentation2012

  • 1. DRUGS AS A CAUSE OF MALNUTRITION • Mario Wilmath
  • 2. OBJECTIVES • At risk populations • Drugs Classes • Treatment • Prevention
  • 3. Physical Interactions • Ca, mg, fe, al, or Zn can lower oral abs of levothyroxine and quinolones. • Tube feedings decrease phyntoin and levothyroxine
  • 4. Appropriate Prescribing • Established efficacy • Compatible safety • Low risk of drug interactions • Low risk of nutrient interactions • Known adjustments for disease states or organ function • Convenient • Affordable
  • 5. Decreased Drug Effect • Warfarin and vitamin-K containing foods
  • 6. Decreased Oral Intake or Appetite • Meds that alter taste (dysgeusia) – Captopril – Clarithromycin • Decrease saliva production (xerostomia) • Antihistamines, antidepressants, antipsychotics, clonidine, diuretics • Make mastication and swallowing dificult
  • 7. Nutrient-Drug Interactions • Constipation • Inadequate or excessive fluid intake • Need for a tyramine-restriction. • It is advisable to refrain from blaming the medication for side effects while working to minimize the consequences.
  • 8. Choosing a Nutrient-rich Diet • Antioxidants • B-Vitamins and Folate • Calcium Vitamin D • Fiber • Iron Magnesium Potassium
  • 10. REFERENCES • Reuben DB, Herr KA, Pacala JT, et al. Geriatrics at your fingertips: 2009, 11th Editiion. New York: The American Geriatrics Society; 2009.