Snow Lecture 41

The Rest of Chapter 41 Obesity Leptin Food Pyramid

E. Obesity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Body-Mass Index ,[object Object],[object Object],[object Object],[object Object],[object Object]

Maintaining Weight ,[object Object],[object Object],[object Object],[object Object],[object Object]

Fighting Fat ,[object Object],[object Object],[object Object],[object Object],[object Object]

F. Leptin ,[object Object],[object Object],[object Object],[object Object],[object Object]

Parabiosis: mutant mouse surgically attached to wild type mouse  weight loss. Leptin “cures” obesity in leptin deficient mice and in overfed mice. Leptin treatment of human diseases: Congenital leptin deficiency (rare) Lipodystrophy (inability to deposit fat in fat tissue) Leptin action: Hypothalamus (brain) Major area of action-arcuate nucleus Activates pathways that signal satiety and promotes energy expenditure

G. Food Pyramid http://www.washingtonpost.com/wp-srv/nation/daily/graphics/diet_042005.html

What’s wrong with the pyramid? ,[object Object],[object Object],[object Object],[object Object]

http://www.hsph.harvard.edu/nutritionsource/pyramids.html

Summary ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Snow Lecture 41

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