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A Step-by-Step Guide to Creating
Successful Academic-Industry
Partnerships

U

Jon D. Duke, MD, MS
Regenstrief Institute
January 30, 2013
U
Step 1. Know Thyself
Step 2. Know Thy Partner
Step 3. Lay Out the Vision
Step 4. Develop the Contract
Step 5. Define the Infrastructure
Step 6. (Serious) Project Planning
Step 7. Do the Work
Step 8. Review, Articulate, Iterate
Know Thyself
Do you want to partner with
Industry?
NIH Funding
Know Thyself

Source: NIH
Know Thyself

Source: NIH
7+ Years
Photo: NASA Goddard Space Center
Photo: Peter Fleck
Do you want to partner with
Industry?
+ Funding
+ Speed of Action
+ Breadth of Impact
+ Expertise
+ Cutting Edge Innovation
Academy

Industry
The Tenure Track
Source: Open Clip Art LIbrary
Source: US Patent Office
Do you want to partner with
Industry?
+ Funding
+ Rapid Action
+ Breadth of Impact
+ Expertise
+ Cutting Edge Innovation

-

Differing cultures
Some loss of control
Uncertain career benefits
Publication complexities
IP complexities
Know Thyself

What do you have to offer?
Does your work have
translational potential?
Step 1. Know Thyself
Step 2. Know Thy Partner
Step 3. Lay Out the Vision
Step 4. Develop the Contract
Step 5. Define the Infrastructure
Step 6. (Serious) Project Planning
Step 7. Do the Work
Step 8. Review, Articulate, Iterate
Do you know what they want?
Do they know what they want?
Do they understand the
academic research environment?

Photo: Dimitri B
Do they understand the
academic research environment?

Photo: Perkins
Do they have realistic
expectations for funding?
Do they have realistic
expectations for time?
What is the level of
commitment?
At what level does that
commitment exist?
Three Key Attributes:
Respect, Flexibilty, Personability
Ideal Partner
• Experience with academic research
• Realistic expectations
• High level of commitment at high levels in the
company
• Engage as equals
• Flexible approach
• Personable interactions
Step 1. Know Thyself
Step 2. Know Thy Partner
Step 3. Lay Out the Vision
Step 4. Develop the Contract
Step 5. Define the Infrastructure
Step 6. (Serious) Project Planning
Step 7. Do the Work
Step 8. Review, Articulate, Iterate
Define the drivers for the
relationship on both sides
Example Industry Drivers
•
•
•
•
•
•

Develop intellectual property
Increase sales
Mitigate risks
Gain access to experts
Gain access to data
Public relations benefits
Example Academic Drivers
•
•
•
•
•
•

Fund one’s work
Novel research
Build infrastructure
Develop IP
Access to experts
Gain insight into industry
Identify common areas that will
satisfy drivers on both sides
Be Honest
A 'No' uttered from the
deepest conviction is
better than a 'Yes'
merely uttered to please.
- Mahatma Ghandi
Be Creative
With a breadth of drivers,
you may find surprising areas
will meet common goals.
Expect Change
Over the course of your
collaboration, areas of
interest may shift.
The Vision
Step 1. Know Thyself
Step 2. Know Thy Partner
Step 3. Lay Out the Vision
Step 4. Develop the Contract
Step 5. Define the Infrastructure
Step 6. (Serious) Project Planning
Step 7. Do the Work
Step 8. Review, Articulate, Iterate
Fear Not the Lawyers
(but be patient)
Is the contractual commitment
commensurate with the Vision?
Example Funding Mechanisms
•
•
•
•

Up Front Funding
Recurring Funding
Milestone-based Funding
Marketization-based Incentives
How is the Work Defined?
Are IP Issues Addressed?
Are IP Issues Addressed?
• Who will own the IP?
• Do you have the ability to make assurances?
– University requirements
– Multiple university affiliations

• Involvement of researchers not part of this
contract?
• Relationship between IP and publications
Publication Rights
• Ensure freedom to publish
• But expect oversight from technical to
‘interpretive’
• Build in time for reviews and IP consideration
• Shared authorship brings complexity
• Recommend a Publication Committee
Steering and Tie Breakers
Expect an Escape Clause
(make sure it’s mutual)
keep the lines open
Step 1. Know Thyself
Step 2. Know Thy Partner
Step 3. Lay Out the Vision
Step 4. Develop the Contract
Step 5. Define the Infrastructure
Step 6. (Serious) Project Planning
Step 7. Do the Work
Step 8. Review, Articulate, Iterate
Steering:
Guidance, Vision, Approval
Operations:
Running the Day-to-Day
Partnership
For Large Collaborations
Multiple Project Teams
Internal Advisory Board
Cross-Cutting Cores
Steering Committee
RI
Internal
Advisory
Board

Merck
Internal
Processes

Operations
Committee

Project
Team

Project
Team

Operations
Committee

Project
Team

Project
Team

Data Core
Biostatistics Core
Natural Language Processing Core

Project
Team
Step 1. Know Thyself
Step 2. Know Thy Partner
Step 3. Lay Out the Vision
Step 4. Develop the Contract
Step 5. Define the Infrastructure
Step 6. (Serious) Project Planning
Step 7. Do the Work
Step 8. Review, Articulate, Iterate
P
P.P.P.P.P
The Single Most Critical Factor
Idea

a long way
Ensure that everyone who might
be interested later is informed
now
Project Leads Should Be…
•
•
•
•

Genuinely interested and invested in the topic
Collaborative in nature
Aware of the overall partnership vision
Provided sufficient resources (FTE, PM, admin)
Write a Comprehensive Project Plan
• Be explicit about the division of labor in
preparing the project plan
• Be aware of any protocol review requirements
(e.g., IRB, DRC) up front
• Provide buffer in project execution,
recognizing communication challenges
Do both sides still see value in
the project that has emerged?
Step 1. Know Thyself
Step 2. Know Thy Partner
Step 3. Lay Out the Vision
Step 4. Develop the Contract
Step 5. Define the Infrastructure
Step 6. (Serious) Project Planning
Step 7. Do the Work
Step 8. Review, Articulate, Iterate
Begin with the End in Mind
Keeping Things on Track
Transparency
Monitor team relations
Avoid Assumptions
If Things Go South…
Review Goals and Plan
Team Changes
Terminate
Step 1. Know Thyself
Step 2. Know Thy Partner
Step 3. Lay Out the Vision
Step 4. Develop the Contract
Step 5. Define the Infrastructure
Step 6. (Serious) Project Planning
Step 7. Do the Work
Step 8. Review, Iterate, Articulate
Review with all participants
what worked and what didn’t.
Iterate on your processes.
Articulate the value of your
partnership to your stakeholders.

Help your partner do the same.
Steps to Creating a Successful
Academic-Industry Partnership
1. Know Thyself
2. Know Thy Partner
3. Lay Out the Vision
4. Develop the Contract
5. Define the Infrastructure
6. (Serious) Project Planning
7. Do the Work
8. Review, Iterate, Articulate
Questions?
jonduke@regenstrief.org

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Step-by-Step Guide to Academic-Industry Partnerships

Hinweis der Redaktion

  1. Many of you have flipped through a magazine, seen the drug ads with people frolicking in the fields…Now turn the page-- 6 point font, dozens or even hundreds of side-effects listed.Partially medico-legal reasons, partially just due to thorough studies.I do not have data on average number of side-effects per drug, but based on my work in this project, it is between 65 and 70; with several >200.
  2. Early in academic season for fellowsA true work in progressFeedback, suggestion, critiques To shape direction over next 2 years
  3. Early in academic season for fellowsA true work in progressFeedback, suggestion, critiques To shape direction over next 2 years
  4. Different cultures, different expectations on timing, workflow, etc
  5. Some loss of control over projects
  6. Questionable benefit to your career
  7. Publications layer of complexity
  8. IP complexities
  9. Translational potentialUnderlying technology?Application / implementation?Enhance awareness, improve use of a technology, adherence, etc
  10. [For this talk, we are assuming you have a partner in mind; Will have a separate talk on how to identify potential partners]
  11. The obvious question is do you know what they want?
  12. The better question is..
  13. The better question is..
  14. The better question is..
  15. Depends how much time and energy you will invest
  16. You want this commitment to be at as high a level as possible, to avoid rug getting pulled out prematurely. Goes to VISIBILITY.
  17. The better question is..
  18. [Recognizing that some partnerships will be large scale with mission statements etc, and others will be smaller, but all should have some “Vision”]
  19. Avoid tendency to lovefest
  20. OsteoCoE, domain agnostic, focus on information, methodologies etc
  21. Expect that the details will change as you get to better understand each other’s organizations
  22. May be huge, may be small. But we can articulate and justify why we are doing it. We have a mutual understanding of what may be involved. We know where each other’s drivers are.
  23. [Could be a topic unto itself, but to focus on the basics]
  24. Took us 6 months
  25. Time funding,
  26. Time funding, etc
  27. Took us 6 months
  28. GOVERNANCE. Steering committee, and recourse (tie breakers).
  29. Took us 6 months
  30. Keep the lines of communication open throughout the contracting process. Don’t let the drafting process lose the momentum for what you are trying to do.
  31. [Recognizing that some partnerships will be large scale with mission statements etc, and others will be smaller, but all should have some “Vision”]
  32. Program manager, project managers
  33. Program manager, project managers
  34. Program manager, project managers
  35. [Recognizing that some partnerships will be large scale with mission statements etc, and others will be smaller, but all should have some “Vision”]
  36. Planning. Take high level ideas
  37. Planning. Take high level ideas
  38. No love fest!
  39. [Recognizing that some partnerships will be large scale with mission statements etc, and others will be smaller, but all should have some “Vision”]
  40. Papers, Presentations, Visible Output
  41. Trans- Status ReportsTeam Relations – leads may not get alongAssumptions- CRO vs Collaboration
  42. Trans- Status ReportsTeam Relations – leads may not get alongAssumptions- CRO vs Collaboration
  43. [Recognizing that some partnerships will be large scale with mission statements etc, and others will be smaller, but all should have some “Vision”]
  44. No love fest!
  45. Need to articulate the value both internally and help your partner to articulate the value to their own stakeholders . Go back to the drivers.
  46. [Recognizing that some partnerships will be large scale with mission statements etc, and others will be smaller, but all should have some “Vision”]