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Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
Bioinformatics core services, the IBMCP case
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Bioinformatics core services, the IBMCP case

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Description of the work done at the Bioinformatics Core Service of the Institute for Plant Molecular and Cell Biology (Instituto de Biología Molecular y Celular de Plantas, IBMCP,www.ibmcp.upv.es). The IBMCP is a research center of the Polytechnic University of Valencia (Universidad Politécnica de Valencia, UPV, www.upv.es) and the Spanish Research Council (Consejo Superior de Investigaciones Científicas, CSIC, www.csic.es) of Spain.

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Bioinformatics core services, the IBMCP case

  1. 1. M D S A Q P A R N V A V RT SVDY FGH GPS MRS NMK ACDE FGH SGYP TAC MDT DEE GHQ GYPN HGY KACD GQR GPS MRS GYP ACD H C H M K M HQ K S P F H M I M FG FMGP PNM EEF KFG HGY IMDT PNM EDER FGH VDG DTA NMK DERS HMR YPNM EEF EEF KFG MRS PNMK EF M M M EE RSGY ACD YPN MRS VDG SHGY ACD PNMK GPS DGI GYP CDE MKFG SHG DPQD ACD YPN FGH HGY PQDE C D Q H H K G HQRT SVD KFG GPS HMR PNMK SGY EEFM PSV MRS MKA YPN GHMR PSV HQRT SVD PNM MRS SVD QRTA P G P FM FG G R G G P M H Y D G Y F H FM PN GH K EFMG YPN DEE MKF SHG FMGQ TAC EEFM KFG HGY QRS NMK RTIM MKF EFMG RSG MKF IMG KFG MGQR M E G M Q N D R N R P M C S N D E E Q F PN MG RT C GQRS RTA VDY GHM CDE FGHQ TAC DYPN HMR EEF SGY FGH MGPS ACD YPNM GYP GHQ PSN DEE PQDE A M Q G S K F R K A K Q S D F V G K F D KF QR MG E KFGH MGP PNM MDT PNM FGHQ GPS NMKF MPQ FMG PNM GHE YPNM QRS MGQR NMK HEF VDP PSV TACD F M P DE NM M G Y F G Y E G P F K G R GI GY PS P CDEE RSG SVD SHG PNM DEEF SGY VDGI QDE GSH NMK RSH EEFM DEE SHGY MKF IMG TIM GHQ AGAA Y A R P R Q P N R Q Y M F HG M K MG FMGP GHM SHG KAC MGQ MGPS SVD PSVD SGY FGH PQD VDP SVDG GYP HQRT GHQ NMK GAA GGT F N M D G F R F YP QDEE DEE NMK HMR YPN DEEF EEF IMGP FMG MGQ NMK PSV MGPS MGP GQRS KFG NMK GYP AGC TGGG AA C E M D F T G G A P F P P T M Q I G FG YP SH VD QRTA VDY NMK RSH VDP RTAC HQR TACE DEE RSG TIM QRT ACEE EEF GYPN HGY HMR GCT CGG AAGC C M R A GH MGPS GYP FGH GPS GHQ MKFG GHM DTAC MGQ GHQ FGH HMT TACD GSH VDGS KFG TCA AAA GGA GGGT F F C M K E MQRS NMK RTI MKF YPN NMKF GIM DEEF MKF PNM KFG IMD PSVD GPS YPNM GGG AAT AGC TGG ATCG P N C DE PN D M G G G Q Y T Q D P G G SN NM TA Y RSGY FGH MGP GSH SGY GPSV VDP HGYP SHG GYP SVD EFM DEEF PSV ACAT AGC AGC CGG TAA AAGC G Q K G A S G S G R E C F S A S T M C A VD GP AT M YPNM GHE GPS MGQ EEF IMGP VDG PSVD GQR EFM KCD MTA EEFM KFG CGGA TCA AAG AAG GTC CAAA F G F M A F M G S M D H G EE SH MK EEFM DEE TAC QRT MGP EFMG EEF ACDE YPN KFG ACD YPN TAAG GGG GGTT ATC GGG GGT CTG N D G K G H C G A VD SGYP AC DTA HQR KFG DEEF CDE TACD QRT QRS PNM PNM QRSG AGC GGTG GGG GCT GGT TGG AGCG 00 T H T A A 0 M Y G M G T R D G C G A FG GY CG GQ FGHM DGI NMK YPN NMK GHMT GIM MKFG EFM QRS SHG EFM GTCA ATC CGGG CGC GAT CGG GCT 1101 1 V E G D G 0 P E A P G A K N A F G 1 HG MR AT NM MGPS HGY DGS SGY NMK GPSV GYP TACD EFM FGH PQD GGG GCTA CAA CTAA CTA AAG CAA 101 0101 0 S E G H T 0 P T 0 V K T F D G M A 1 QR VD AG EE GHMR GPS FMG SGY EEF HMRS GIM TACD PNM GPS GGG CAA CTAA AAA CAAA AGC CTA 001 110 1101 1 M Y A D C 1 D T 0 E M G F D T 1 G G QR TC 00 MK DEEF CDE FMG TAC MKF GPSV GIM QRSG RTI AGA TAA AAA TAAG TAA AAGA AAA 001 101 101 1000 1 A Q C D C 1 N G 0 E A 1 C G A M C 1 QR GC 11 TA IMDT CDE FGH GYP EEF GPSV EFM KFGH GTT AAA GCG AAG GCTG CGG GGGT 110 110 111 111 1011 0 G A 0 E G 1 D A 1 K C 0 G M G M C 0 RS AA 10 VD IMDT PNM EDE FGH EEF DPQD YPN TGGG AAG GCT GTC AAG CTAA GTG 0111 101 010 010 001 0111 1 S G K G 1 D SHGY ACD PNM ACD PSV GSHG GGG GTCA AAA GGG GCT AAG ACGG 100 0101 101 010 100 101 0101 T A 0 K C 0 SV MR C 0 G A 0 NM RSGY HQR TIM SVD AAA GGGG GGT GGGT CAA GTC CAA 011 0100 110 1011 010 101 111 000 H YP G G 1 G 1 C 0 1 R G 1 Q C 0 FG HG T 1 GP AT 00 MG NMKF GHQ EFM AAT GGG GTGG AAA CTAA GGG CTA 010 111 0111 111 1101 010 010 110 111 S EF T 1 1 MR DE YP NMKF CDE AGC ATC CGG AATC AAG GGGT AAG 111 010 101 0111 001 0111 111 101 101 11 G C G 1 0 K G 1 TA MRSH GYP PNM GAA TAA AGAT GCT GTCA AAC GCG 010 000 1010 101 1010 011 010 010 101 0101 1 H A 1 A 0 1 C 0 0 Y A 0 H G 0 A 1 1 CG 01 00 FG VDGS RSG AAG AAG GCT GGAA GGG AATC CTA 000 001 010 1101 011 0001 101 010 011 010 1000 1 Q G T 1 0 A 1 1 T 1 0 S T 1 101 Forment, septiembre 2012 C 0 0 CA 11 01 GP EFMG AGC AAT GAA AAG CGGG AGC CAAA 100 010 111 101 1110 111 1Javier 011 111 101 101 1010 1 0 1 M A 1 0 A 0 A 1 0 T 1 1 T 0 1 Bioinformatics Core Services: a bridge between biologists and software developers
  2. 2. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 “Bioinformatics Core Services” boom.
  3. 3. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 “Bioinformatics Core Services” boom.
  4. 4. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 “Bioinformatics Core Services” boom.
  5. 5. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 “Bioinformatics Core Services” boom.
  6. 6. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 “Bioinformatics Core Services” mission.
  7. 7. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 “Bioinformatics Core Services” mission.
  8. 8. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 “Bioinformatics Core Services” mission.
  9. 9. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q F S E Q Y P P D R TA GP N G RT SGY GH PSV MG EF GY- GPSV FMG GHQinfrastructure PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS computer DER MKF FMG G K MR D FM H Y T T F P T P EF GQ FM CDEE MKF DE PN DEE EFM PNM GH MPQ DEE DGS RSG NMK IMG HQR GHM GIMD FMG ACD M DEE A N C F G E P GY V E EF AC DT HGYP MKA QRS TAC ACD SVDY NMK DGIM DPQ GPS MGQ SGY HQRT MKF NMKF SVD CDE HMT KA M S T R F G N P V QR VDGI MR GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F E H SH G S F M E C N E M S R H F G CE YP DE NMKF KFG DEE GP MKFG MRdata managementMGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G C P M - A C S M PN KFGH MDT HGY YPN MKA DEEF ACD FGHQ FGH DGI DPQ GSH GPSV EEF QRTA MGQ GQR GHM SVD TCGG Y M I K F D N T D C N D P S V M H K Q M A HG SV KF P SVDG HMR MRS GYP VDP GHQR PNM YPNM GPS MGP PSV EEF DTAC KFG CDEE EEF PNM IMG AAG AAAG G M D G Y GP M C Y S D T H I Y G A F M C SH MG RT M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I V A RT MGPS S PN MKFG QanalysisVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY - data H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N- software development A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 S D P D F F A RSGY bioinformatics consultation DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 AC ACDE VDY NMK GIM NMK FMGP C -T A 1 T MK GQ A A 0 QR QRT GPS GYP SVD GYP DEE DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V - bioinformatics training A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 “Bioinformatics Core” services provided.
  10. 10. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY- GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS Excel F DE M F T M R T G F H P D T K P EF GQ FM CDEE MK DE PN DEE EFM PNM GHM MPQ DEEF DGS RSGY NMK IMG HQR GHM GIMD FMG ACD M DEE A N C F G E P GY V E EF AC DT HGYP MKA QRS TAC ACD SVDY NMK DGIM DPQ GPS MGQ SGY HQRT MKF NMKF SVD CDE HMT KA M S T R F G N P V QR VDGI MR GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Regular computer skills of experimental researchers.
  11. 11. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY- GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS BLASTF DE M F T M R T G F H P D T K P EF GQ FM CDEE MK DE PN DEE EFM PNM GHM MPQ DEEF DGS RSGY NMK IMG HQR GHM GIMD FMG ACD M DEE A N C F G E P GY V E EF AC DT HGYP MKA QRS TAC ACD SVDY NMK DGIM DPQ GPS MGQ SGY HQRT MKF NMKF SVD CDE HMT KA M S T R F G N P V QR VDGI MR GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Regular computer skills of experimental researchers.
  12. 12. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY- GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS CLUSTAL DE M F T M R T G F H P D T K P EF GQ FM CDEE MKF DE PN DEE EFM PNM GHM MPQ DEEF DGS RSGY NMK IMG HQR GHM GIMD FMG ACD M DEE A N C F G E P GY V E EF AC DT HGYP MKA QRS TAC ACD SVDY NMK DGIM DPQ GPS MGQ SGY HQRT MKF NMKF SVD CDE HMT KA M S T R F G N P V QR VDGI MR GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Regular computer skills of experimental researchers.
  13. 13. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY- GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS VectorNTI DE M F T M R T G F H P D T K P EF GQ FM CDEE MKF DE PN DEE EFM PNM GHM MPQ DEEF DGS RSGY NMK IMG HQR GHM GIMD FMG ACD M DEE A N C F G E P GY V E EF AC DT HGYP MKA QRS TAC ACD SVDY NMK DGIM DPQ GPS MGQ SGY HQRT MKF NMKF SVD CDE HMT KA M S T R F G N P V QR VDGI MR GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Regular computer skills of experimental researchers.
  14. 14. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE N Y DY NMKF GIM RSG ACgeneratingGmore thanP1TB RS GYP MsequencingDdata D MGP EFM experiments D YPNMK MTAC VD I DGIMD RSHG Y NMK GQ ofS raw KFG FGHE RSHGY Q EE PSV P F E G C TA GPSV YP SVD GQ QRT SG H N G M E M P S K D R G G M RSG GP EFM GH ER MKFG MGP GPSV FGH RSH EEF MGQ HGYP PNM FGHM SVD TIM ACE TAC PSVD M K P EF GQ F Y D F D E M PQD R M K N S G KF MT M DEEF ACD PNM CDE GYP CDEE EEF YPNM FGH M+ DEE VDG QRSG PNM TIMG GHQ FGH GIM EFM TACD M Q A D T K F EF AC D Y S S E MD SHGY NMK GQR RTA TAC PSVD PNM VDGI VDP MGP FMG RSG GHQR NMK PNMK PSV KCD GHM MKA T GI G P S Y PS P R Q N M F M R Y QR VD G F HQ EE KF HM SHGY EEF KFG GHQ EFM QRSG Mtemporary ACD FMG NMK SHGY RSG EEFM YPN PNM GYP EEF G IMGP CEE files S FG F E H GP MK MR TACD PNM NMK CDE FMG DEEF QRT HMTA MDT QDE GYP VDG FMGQ ACD QRSG SGY MRS PQD GG H N A D Y I R YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C +S V H D N G M E R C G G P R S F G M P F G SH P MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG processed data H I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RS VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM +EF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG E M T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PN DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G RAM memory-hungry software C S G G E M G S T G E A G D E G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R =N T T Q QRTA GYP GHM SVD VDG HMRS GYP EFMG GYP GYP GYP TAA AATC AAA AAAG TAA AGC GAT 011 0101 G H S C G M G C 1 F MGP PS FG H A E C 0 T RS AA SH SH F EDER NMKBIG COMPUTERSDNEEDED:GQ AAG TGC AGCG GGT AAAG TCA GTT 010 100 1111 F FMG MK HMR AC HMR VDGS M K D P G M C T G N C 0 EE E F G G G G A 0 CA 01 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 A 1 T T MK GQ A A 0 SV YPN PN EEF TAC TA C RAM QR QRTA GPSeveralVD GYhard-disk TGGG CGB AA TCG CTA GGGT GGG 1101 010 000 110 010 M GH D G + 32 G GPS TB CD M G 1 M C S G 0 S T 1 H 1 EF KF C AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: hardware (I).
  15. 15. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D F P M F PS DE K G Y P Very high D RSHGY PNMK GQ S GYPN DY NMKF GIM RSG ACD PNM MTAC DGI GIMprocessingRtime MKFG GHE SHGY DEE SVD MGP EFM C SV D Q V F Y S E Q Y P P D R TA GP H N G RT M EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T EF GQ FM CDEE MKF DED PNM EEF EFMG NMK weeks D months)SGY NMKF MGP HQRT HMT IMD MGP CD (days / FGHMR MPQ /DEEFM DGSH R E M Y F N G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MK GIM PQ PSV MGQ GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H S E N E H S G EE MKF FG EEF QR FMG TIM + CE TAC EF PNM SH sequence YP GP MKFG MRS ACD 300,000,000MsequencesMTA 1/10 second per MGQR CDE RSG GYP RSH PQDE G G EE G N NMK CD F D QDE GY VD R P S PN KFGH MDT HGY YP MKA DEE ACD FGHQ FGH DGI DP GSH GPS EEF QRTA MGQ GQR GHM SVD TCGG =M V D M Y M I F D N T D C N P S M H K NMK SV Q A HG S KF P SVDG HMR MRS GYP VDP GHQR PNM YP10 GP60 GP60 SV24 F DTAC KFG CDEE EEF PNM IMG AAG AAAG E = 347.22 days P/ E 300,000,000 G Y GP FG FGH RSH GPS KF HGY RSG / EFM /RTIM /FMG ACD IM PNM DTA ACD SGY QRT GTT GC AGC K M M G A M E H EF YPNM NMK FGH TIM PSN VDGS MGQ ACDE GHQ CDE HMT SVD SHGY GIM IMDT GQR KFG GGG CAA TCAA G P F M F D C G P T K K M D T G S R G QR FG TG SV RSGY PNM FGH EFM MGP CDEE HQR PNMK PNM NMK FMG GHM GPSV SVD DEEF YPN GGG GGG GGG CAAA A Y Y G P A F G F K P C Q Q A KFG GY M T GH EE GG NM QRSG PNM MKF DEE MDT AffordableSsolution: computing G VDP DGSH AAA GGT GGT TAA GGTC A H QR G SGY ACD NMK EEF EFM clusters M GS N P G C MG SHGY YPN MTA DGI GYP SVD FMG MGQR QRT SGY GHD CDE MGPS PSV AATC TCG ATC AGC GGG GCTA F G G H A E G G A T H R G H F T P I A SV KF AA VD GQRS KFG MGP MRS FMG ACDE DEE MKFG EDE PNM QRT QRT EEFM AGC TAAG TAA CGG GGG GAA GGGG D C M PS FM C A 0 E H G F Y G N C D T T GH GH AC E GYPN DEE MKF CDE IMD MDTA GYP MKAC RSG MKF KFG MKC CGGA AAG AAAG TAA CAA AGC GGG 1110 A M A C Q C 0 DE R S H A G N C TA GYPN HMT SVD DGI MRS GYPN FMG GYPN YPN GYP AAG ATC AAAG AAG TAAT GCT GAT 111 101 Q QR G G A E A H A 0 P S A S H C H G M G GH SV CT 10 ER NMKF FMG MGP KFG MRS ACDE MRS DGSH GQR AAG GCT GCG GGTC AAG TCAA TTA 010 000 111 F ED M 1 T MK CD YP CDEE EEF YPN FGH MDT KFGH PSV EEFM TCA CGC TAA GGG CGGA GGG GGGG 101 110 101 11 G A K C 0 D G 1 MK GQRS RTA TAC SVD PNM VDGI PNM EFMG ACD GGG AAG AAG CGGT AAG GTGG GTG 010 010 001 1000 0 Q T G Y T 1 Y A 0 R G 1 M E G S T 1 GP CT 01 EF KFGH GHQ EFM RSG MGP QRSG ACD GIMD GGT AAG GTC TAA AGGC TCG AACG 011 101 010 111 0000 1 F G 1 T A 0 F C 1 E A 0 M D A M A 0 GQ GG 10 PN PNMK ACD EFM DEE YPN GQRM PSV GATC AGC TGG AAG GCA CTAG ATC 0101 110 110 010 000 1001 1 Y Y C G 1 G PNMK QDE RTA RSG EFM EFMG TAA GCTA GGG GCG AAA AAG GCTA GA1 1111 110 010 011 111 1011 P 1 SH GY C A 1 A 1 1 Q A A 0 A 0 GQ DE DE TC 01 AC H PSVD FGH EFM PQ347.22 AG CAA /C50 computerTnodes CTA6.94 1000 101 000 101 010 0110 C AA days AA CTA GGG AA C GAA G = 101 days A RS MG MK QDE SVD QRT AG GGT AAT AAG TGG CT GCG AA 010 010 110 101 010 011 01 01 N I A A 1 P G 1 RT MGPS VDP IMG FGH GGA TGGG GCT GTCA GGG AAA TAA ATC 1011 011 1101 000 110 101 011 1101 1 S C 0 A 0 0 C A T C F G 0 Javier 10 011 00 10 G 0 MK GC 1 1 0 00 HE IMGP HQR YPN AAG CGG GGAA GGG AGAT AAG AAA GCT 111 1110 101 1001 1Forment, septiembre02012 101 1 1 T T 10 G A 1 Modern Biology requirements: hardware (II).
  16. 16. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS - Science is an international collaborative effort E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: network accessibility.
  17. 17. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS - most bioinformatics tools run under Linux H E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GS SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G - computer clusters run Linux S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G AA Linux 0 YP YPN KAC EEF CDE GYP MGQRbioinformaticians Guse GC GCTA AAT 1010 111 011 101 100 1100 11 PS AGAT AAG GTG G A 0 A G HG YPNM PQD QRT QRS EEF EEFM CTA AGCT CGG AGC CAA AAA AGCT AGA 0111 111 101 101 111 0101 1 S G D A 0 G A 0 D C 1 H A 1 1 A D A 0 MG GT 00 SH GPSV KFG EEF DPQ TAC GAAA TCA TCAA GCT GGG AAT GGA AGCT 010 0100 010 100 010 101 1011 R M M A 1 G 1 1 R C 1 D G 0 A 1 A A 0 SV CT 01 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: operating system
  18. 18. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS - high rate ofEnew algorithms, analysis and types of data T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H - lack of user-friendly softwareH A Q F V G N Q M T Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E A F M G N P SV RS Q -Nrequired use ofEcommand line tools HM S V GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C GG T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA Tversus CAA TCG CTA GGGT GGG 1101 010 000 110 010 G GCTA M GH M 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: software
  19. 19. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS - FASTA format M E T M EF GQ FM CDEE MKF DED PN EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: direct data manipulation
  20. 20. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS - GenBank format E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: direct data manipulation
  21. 21. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS - EMBL format M E T M EF GQ FM CDEE MKF DED PN EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: direct data manipulation
  22. 22. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS - fastq format E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: direct data manipulation
  23. 23. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS - Perl E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G M E R C G G P V R S F G M P F G SH PS MK YP PSVD GHM HMR HGY SVD FGHQ YPN GYPN MGP IMG GPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E S A M G N P SV RS V -NPythonF GP E Q HM GG YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 D P T P P A P A G A 1 MT PN CT GQ HQRT SGY FGH PSV SVD GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 M G R S G S G 1 P G 0 K S A D T F C 0 MG QR TA KF DEDE PNM EEF FMG NMK GHMR TAC GHMR VDG FMG AAA CTG AAGC GGG GAAA GTC GGT 101 010 0111 M C E C 0 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 C T MK GQ N A N A 0 -T R QR R TA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 HQ G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Modern Biology requirements: programming skills
  24. 24. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M N M A S K Q G C H D N T S H R F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N S G M PS E R C G G P V R F G M P F G SH MK G IMGP G programs: YP PSVD - HM HMR HGY SVD FGHQ YPN GYPN UniversityPS DEE MDTA MKF ACDE DEE YPN TIM TAA CAAA C G progressively included in M G G S M R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y G E G P - use of Linux Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S YP C 1 D P T P P A A G A 1 MT PN CT GQ HQRT SGY - GH PSV SVD GHMR language GY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 G EEFM H M G F programming H G R A F EDER NMK EFM MGP MKF HMRS ACD HMRS DGS MGQ AAG TGC AGCG GGT AAAG TCA GTT 010 100 1111 K D P V G M C T G N C 0 E F G G G G A 0 EF CA 01 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH P M RS G 1 M C S G 0 T 1 H G 1 EF KF C C AA 11 Q EFMG M R MTA FG DEEF databaseQqueryVDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK G E -M N N A 0 G 0 YP YPN KAC EEF CD GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Biologists must have computer skills...
  25. 25. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M EF GQ FM CDEE MKF DED PNM EEF EFMG NMK GHMR PQD EEF GSH SGY NMKF MGP HQRT HMT IMD MGP CD E M Y D F N M G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M - reusability ofRhardware and softwareG N M A S K Q C H D N T S H F G NM PS VD QR VDGI MRS GYP FMG GHQ HQRT MGP SGYP PSV GPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F H G S F M E F C N E H M S R H G F G EE CE YP GP MKFG MRS ACD NMK MKF CDEE MGQ EEFM RTI MTA DTA DEE GYPN DGS MGQR CDE RSG GYP RSH PQDE G H A Q F V G N Q M T H Q N D F A H D YP IM RS YP MKFG IMD SHG GYP NMK QDEE TAC KFGH KFG VDG VDP DGS MGPS DEE HQRT FMG MGQ FGH PSV ATCG C D N G E C G G R F G G SH GYP DP H R NM PNM GPS GPS SV EF MK YP PSVD - HM HMR algorithmsQand programming Pskills MDTA MKF ACDE DEE YPN TIM TAA CAAA C P GY V FG E G same SH M G G Y S D IM MG R M NMKF KFG HMR MGP NMK GSHG QRS DEEF QRT EEF TAC DGI GYPN MDT DTAC RSG GHQ GGT AAG AAAG I M G M H Q EF YP G I S V A PN MKFG QRT MGP SVD EFM RTAC KFG MKCD FGH GPS RSH VDG DGIM FMG NMKF TGG GTC GTC ACG D GY H K G M E E S A F M G N N P SV RS Q V HM GG GP YP MKFG GHE EFM ACD FGH GYPN GYP YPNM EEF KFG MGP GPS PQDE HGY ACGG GGG TGG TCA CAA Q SG T F A NM QR PN NMKF CDE IMD NMK GSH GQRS RSG TACD PNM DEE EFM SVD VDGS CAA GGGT GGG CTA GGT AA Y - same type of data G E G P Y C A FM GSHG GYP HMT VDG HGY PSVD EFM FMGQ HQR RSG FGH ACD IMGP GPS TAAT ATC GAT AAG TGG AGCT G S G G E M G S T G E A G D E C G T A PS MK GA SV MGQR MKF FMG HMR EFM TACD CDE NMKF DED YPN HQR HQR DEEF AAG CTAA CTA GCG CGG GGA TGGG 0 P F C G N A A 0 E G C E G A P G D C G FG FG AA EE SGYP CDE NMK ACD GIM IMDT HGY NMKA QRS NMK MKF NMK GCGG AAA GAAA CTA TCA AAG CGG 1111 0 D R A G G S C 1 P T P P A P A A 1 MT SVD DG PN CT GQ HQRT - GY FGH efficient GHMR HGY EEFM HGY HGY SGY CTA TAAT GAA CAAA CTA AAG AGA 101 0010 V and cost-effective R S more GP M G S A F EDER NMK EFM MGP MKF HMRS ACD HMRS DGS MGQ AAG TGC AGCG GGT AAAG TCA GTT 010 100 1111 K D P V G M C T G N C 0 E F G G G G A 0 EF CA 01 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 … or use centralized core services.
  26. 26. G V S S G M F Q G F F Q F P H K F P T E GH EEFM QRS FMG EEF KFG EDER NMK MGPS DEE HQR NMK PNM NMKF FMG GHMR NMK ACD FMG DEE DYP F D D P E G C P P E M Y C MK AC FM CDEE TAC YPN ACD SGY DEEF DTA MKFG HGY RSG GYP CDE NMKF HGY PNMK QDE RTA PSV RS E K K S G D S P NM PQDE RTA GIM SHG PNM MGQR TAC DGIM YPN VDG MGQ GQR QRTA GYP HMRS HGY SVD GHQ EFM PNMQ R Q G S M S Q Y M E D S P D V G F H Y MR EF KF SV KFGH PSV FGH SHG DEE KFGH GPS MRSH MGP CDE EEF KFG EDER MKF GHMR IMG SNM ACD RSG EFMG S R D K NM EFMG NMK GHM TAC PNM EEFM FGH DEEF DTA TAC PNM ACD GYPN MKF HQRT MGP PNM MGQ QDE SVDG D Y F P M F PS DE K G N Y K P DY NMKF GIM RSG ACD PNM MTAC DGI GIMD SHG PNM QRS GYP MKFG GHE SHGY DEE SVD MGP EFM C SV D R Q V F Y S E Q Y P P D R TA GP H N G RT MG EF GY GPSV FMG GHQ RSG KFG MGPS PSV FGHM SHG EEF GQR GYP PNMK GHM SVDP IMG ACE ACD SVD M RS E T M E H EF GQ FM someMKF Daway M EEF EFMG NMK GHMR requirementsGY NMKF MGP HQRT HMT IMD MGP CD DE N far ED YPN from day-to-day MPQD EEF DGS S E- C M F G EF ACDE DTA GYP KAC RSG TACD CDE VDYP MKF GIM PQD PSV MGQR GYP QRTI KFG MKF VDG DEE HMTA A M M S K G C H N T H F G NM MGQ QR RTA PS YPN SVD PS VD QR VDGI MRS GYP experimental MresearchersPS EFM DEE MGQR KFG GYPN GYP FMG NMK MKF YPNM F G SG H HQ P G of EF G E P PS KFGH RSH CDE MKF KFG DEEF GQR EFMG TIM TAC TAC EEF YPNM GSH GQRS DEE SGY YPN SHG QDEE G M N D G N FGHM DTA GYP PNM KAC EEFM CDE GHQR GHM GIM PQD SHG PSVD EFM RTAC GQR QRS HMR VDP CGGG P DY NMK GIM RSH HGY PNM PQD RTA MKF MKF SVD SVD VDG FMG CDE GHQ EFM FMG KFG GPS GAT GC D N E Q A A Y S M M E P P F N D E A RS GP NM GY GPSV FGH GHM SHG PSV KFGH GYP SGYP FMG TIM MGP CDE IMDT NMK TACD CDE GYP RTI TTA GCAA GC Q FM PNMK - KF GHM computer-oriented E HQR DEE MTA VDG HGYP IMD MDTA QRS FGH GGG AAA CAAA moreR TIMG PSNM DGSH MGQR ACDE thanC F H S M E Y G D GYPN MKF HQR MG PSV EEF RT MKFG MK KFG GP MRS SVDG DGI EFMG NMK GTG GTC GGT AACG V S N N P S R Q V H G G G HEF M G N E D P A FM GG Q SGYP MKFbiology M TAC KFGH GYP SGYP YPN DEE KFG FMG MGPS PQD SHGY ACG TGG TGG ATC TCAA G EEF oriented M R N G A N Q H D D E A KF D C G R G M F G NM GG G HGYP PNM TAC GIM YPN VDGS MGQ GQRS RTA GYP HDE DEE GPSV SVD ATCA CGG TCG GCT GGG CTAA D G A Y Q T P FM GS F G C G SG FGHM PSV RSH GPS DEE EEFM FGH DERS MKF RTA TIM FMG GCTA AGA AAGA GAA GGT AAG GGG D QR V M R A G N G PS FMG NMK EFM GHM EEF DTAC ACD PNMK CDE GYP GHQ GHQ CDEE AAA GCTA GCT AGC ACG CGG GTGG 00 F CD F A A T G F S A EE SGYP - DE NMK interestedDin HGY NMKdevelopment NMK GCin tools AAA CTA TCA AAG CGG 1111 0 A DGIM IM S tools GQR PNMK NMK Pthan G CAA G use A C more T D R T Q QRTA GYP GHM SV VDG HMR GYP EFM GY GYP GY TAA AAT AAA AAAG TA AGC GAT 011 0101 G H S H C H G M G S C 1 F H A E C G 0 T GP RS AA F EDER NMK EFM MGP MKF HMRS ACD HMRS DGS MGQ AAG TGC AGCG GGT AAAG TCA GTT 010 100 1111 K D P V G M C T G N C 0 E F G G G G A 0 EF CA 01 A RSGY ACD CDE DYP MKF GIMD MKF MGPS DEE GGT GCG GCT GTGG GCG GGGG GGG 011 011 101 0011 V A 1 T C T MK GQ N A N A 0 QR QRTA GPS GYP SVD GYP DEEF DTA TGGG CTA CAA TCG CTA GGGT GGG 1101 010 000 110 010 M GH - more interested in more academically profitable work M G 1 M C S G 0 S T 1 H G 1 EF KF C C GP AA 11 FG DEEF GQR EFM MQR MTA VDGI CGG CAAA GGG GCT AAG GAT CAAA 110 0010 100 011 000 101 M MK N N A 0 M G 0 YP YPN KAC EEF CDE GYP MGQR GPS AGAT AAG GTG GAA AGC GCTA AAT 1010 111 011 101 100 1100 11 M T 1 M T 1 S A 1 D G 1 G A A F A 1 TA CG 10 SH GYPN DPQ HQR GQR DEE DEEF GCT AAGC ACG AAG TCA CAA AAGC AAG 1011 011 110 010 111 0010 01 V A 0 A T 1 Q T 0 G T 0 H A 0 C A 1 FM GG 00 RS MGPS MKF DEE VDP RTA AGAA GTC ATCA AGC GGG TAA CGG AAGC 101 1010 101 010 101 110 0101 1 S C 0 TI GPSN DPQ MGP GHQ GAA GGGG CTA TCAA GGT AAG AAG TCA 0110 110 1011 001 101 010 111 1010 R M V G 0 G 0 1 G A 0 I A 1 G 1 T 1 1 KF CT 11 Javier 010 EF MGPS QRT PNM AGC GGG GAAA GGG GATC AGC AAG CTA 110 1100 010 0010 Forment, 1 100 02012 1010 0septiembre 10 H I G 1 1 1 C 1 Y A 00 10 A 1 G 1 1 TA TG GH AA 11 Collaboration with bioinformatics research groups.

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