http://www.baseballtvschedule.net/2012/01/2012-mlb-opening-day-schedule/ The 2012 MLB Opening Day Schedule actually kicks off at the Tokyo Dome this year. The Seattle Mariners and Oakland A's start the MLB season on March 28th and 29th playing the first 2 games of a 3 game series. The next opening day game is on April 4th seeing the Miami Marlins opening their new stadium and the remainder of the MLB teams starting the season on either April 5th or 6th, 2012.