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Signs and Symptoms of Chemical Exposure -- CSUEB
1. CHEMICAL EXPOSURE ROUTES
1. Inhalation
2. Direct Contact with Skin (Absorption)
3. Ingestion
4. Injection There are 4
ways a chemical
can enter the
body
2. • Inhalation – most common route
• Breathing in gases, vapors,
aerosols, mists, fumes, fibers, or
particles
CHEMICAL EXPOSURE ROUTES
3. Direct contact with skin is the next most common
route of exposure
Absorption through skin depends on:
• Concentration, solubility of chemical
• Condition of skin – intact or broken (e.g.,
scrapes, wounds, etc.)
• Duration of contact
CHEMICAL EXPOSURE ROUTES
4. Ingestion
Mouth contact w/ contaminated
hand or other item (e.g., pen, lip
balm, cup)
CHEMICAL EXPOSURE ROUTES
5. Injection
Contact w/ contaminated
needles or other sharp
items could inject
chemicals into the body
CHEMICAL EXPOSURE ROUTES
6. SIGNS AND SYMPTOMS OF EXPOSURE
• Be aware: chemical exposure may cause local effects such as a skin rash at the
contact site, or systemic effects such as dizziness or nausea.
• Solvents
• Inhalation: headache, nausea, dizziness, lightheadedness
• Skin contact: dry skin, redness, irritation
• Corrosives
• Inhalation: irritation of eyes and respiratory system
• Skin contact: redness, itching, tingling, burning, blistering
7. SOME CHEMICALS MAY HAVE UNIQUE EFFECTS
Readily penetrates skin barrier and can carry other chemicals w/
it (e.g., small molecules dissolved in DMSO)
Hydrofluoric Acid (HF):
• May penetrate skin and tissue w/o causing
immediate pain
• Replaces calcium in bone – severe
throbbing deep in tissue hours later
Hinweis der Redaktion
There are four ways that a chemical can enter your body. These are inhalation, direct contact with the skin, ingestion, and injection.
Inhalation is the most common exposure route, and involves breathing in gases, vapors, aerosols, mists, fumes, fibers, or particles.
Next most common is direct contact with the skin. The amount of chemical absorbed by the skin depends on the concentration and solubility of the material, as well as the condition of the skin (whether it is intact or broken) and the duration of skin contact with the material.
Ingestion commonly involves eating or drinking food or beverage contaminated with chemicals, but it can involve any mouth contact with contaminated hands or other items.
Injection involves contact with contaminated needles or other sharp items (including broken glass) that could inject chemicals into the body.
It’s important to be aware of signs and symptoms that may indicate an exposure to the chemicals you work with.Chemical exposure may cause local symptoms – a skin rash at the contact site, for example – or systemic effects such as dizziness or nausea.Solvent inhalation can result in headaches, nausea, dizziness, and/or lightheadedness.Skin contact with solvents can cause dry skin, redness, and irritation.Inhalation of corrosive vapor or aerosols can cause irritation of the eyes and the respiratory system.Skin contact with corrosive liquids can cause redness, itching, tingling, burning, and blistering.
Some of the chemicals you work with may have unique health effects and it’s worthwhile to be aware of them:Dimethyl sulfoxide (DMSO) readily penetrates the skin barrier and can carry other chemicals with it (that might not otherwise be absorbed by the skin)Hydrofluoric acid (HF) may penetrate skin and tissue without causing immediate pain, but it seeks out [and replaces] calcium in the bone, causing severe throbbing deep in body tissues hours after exposure.Special precautions will likely be needed for work involving such chemicals. The chemical Safety Data Sheet, the Chemical Hygiene Plan, and your laboratory protocol are all good resources for information on these hazards and how to work safely. When in doubt, discuss the work with your supervisor or Laboratory Manager.