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9 years old girl with High Grade Fever and Rash

  9 years old girl presented with complaint of fever for 5 days duration. There are no
  symptoms of URTI, UTI, AGE, ear discharge, altered mental status and fitting.




                      Image Courtesy of Dr Dr Muna Athirah, Duchess of Kent Hospital



On examination, patient is alert and conscious.       Questions
                                                         1) Describe your finding in the picture
Pulse: rate is 110, weak and volume is poor.             2) What is your complete provisional
Capillary refilling time: more than two seconds              diagnosis?
Peripheral examination: cold periphery                   3) How do you diagnose dengue fever?
BP: 90/40                                                4) Describe grading of dengue fever
Temperature: 38 degree celcius,
                                                         5) Explain regarding phases of dengue
Lung,      Cardiovascular     and     Abdominal
                                                             fever
examination is unremarkable.
                                                         6) How do you manage this patient
FBC was taken and the result are shown below:            7) What is the complication of dengue
WBC:2.9                                                      fever
Hb:14
HCT:42
Plt:60
Answer
   1) Petichae with characteristic of “Islands      6) Grading of dengue fever
       of white in a sea of red”
       ** Usually during recovery phase..

   2) Dengue Hemorrhagic fever in critical
      phase with compensated shock
       ** Physician must able to identify
       provisional diagnosis of dengue, phase of
       illness, hydration and haemodynamic status
       (shock or not) and whether require
       admission

       ? Critical phase: Temperature starts to
       normalize, 3rd to 7th day of illness,
                                                    7) Management for this patient
       thrombocytopenia,    hemoconcentration,
       leucopenia                                      - Admit patient to the wards
                                                       - Insert two large bore IV line, CBD
       ? Compensated shock: Clear consciousness,       - fluid resuscitation 10-20 ml/ kg
       capillary refilling >2s, cool extremities,        crystalloid blus
       weak and thready peripheral pulse,              - QID FBC to monitor HCT and
       tachycardia
                                                         platelet
                                                       - Put patient on IV maintanence
   3) Antibody detection (Dengue Serology
                                                       - Repeat      the   bolus      if   no
      Test      like      Haemagglutination
                                                         improvement. May repeat up to 3
      Inhibition Test, Dengue IgM test,
                                                         bolus (third one with colloids)
      Indirect IgG ELISA test, Dengue
                                                       - 15-30      minutes     vital    sign
      Rapid tests), virus isolation, detection
                                                         monitoring until stable, and then
      of virus genetic materials (polymerase
                                                         1-2 hourly
      chain reaction -PCR) and detection of
                                                       - twice a day monitoring for
      dengue virus protein (NS1 antigen).
                                                         warning sign, general well being
                                                         (appetite/oral intake), bleeding
   4) WHO Classification for Dengue Fever
                                                         symptoms, neurological/ mental
      a) Dengue fever
                                                         state
      b) Dengue Hemorrhagic fever
                                                       - Hourly urine output monitoring
      mild (grade I and II)
                                                       - Daily BUSE/Creat, LFT, RBS,
      Dengue shock syndromes (grade III
                                                         Coagulation profile, Acid base
      and IV)
                                                         imbalance
                                                       - Admit patient to Intensive care
   5) Complication
                                                         unit if condition worsen. Consider
      - Acute abdomen
                                                         blood      product      transfusion,
      - Hepatitis and liver failure
                                                         inotropes.
      - Encephalitis or encephalopathy
                                                       - Dengue notification form (24H)
      - Hypovolumic shock, DIC

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9 years old girl with high grade fever and rash

  • 1. 9 years old girl with High Grade Fever and Rash 9 years old girl presented with complaint of fever for 5 days duration. There are no symptoms of URTI, UTI, AGE, ear discharge, altered mental status and fitting. Image Courtesy of Dr Dr Muna Athirah, Duchess of Kent Hospital On examination, patient is alert and conscious. Questions 1) Describe your finding in the picture Pulse: rate is 110, weak and volume is poor. 2) What is your complete provisional Capillary refilling time: more than two seconds diagnosis? Peripheral examination: cold periphery 3) How do you diagnose dengue fever? BP: 90/40 4) Describe grading of dengue fever Temperature: 38 degree celcius, 5) Explain regarding phases of dengue Lung, Cardiovascular and Abdominal fever examination is unremarkable. 6) How do you manage this patient FBC was taken and the result are shown below: 7) What is the complication of dengue WBC:2.9 fever Hb:14 HCT:42 Plt:60
  • 2. Answer 1) Petichae with characteristic of “Islands 6) Grading of dengue fever of white in a sea of red” ** Usually during recovery phase.. 2) Dengue Hemorrhagic fever in critical phase with compensated shock ** Physician must able to identify provisional diagnosis of dengue, phase of illness, hydration and haemodynamic status (shock or not) and whether require admission ? Critical phase: Temperature starts to normalize, 3rd to 7th day of illness, 7) Management for this patient thrombocytopenia, hemoconcentration, leucopenia - Admit patient to the wards - Insert two large bore IV line, CBD ? Compensated shock: Clear consciousness, - fluid resuscitation 10-20 ml/ kg capillary refilling >2s, cool extremities, crystalloid blus weak and thready peripheral pulse, - QID FBC to monitor HCT and tachycardia platelet - Put patient on IV maintanence 3) Antibody detection (Dengue Serology - Repeat the bolus if no Test like Haemagglutination improvement. May repeat up to 3 Inhibition Test, Dengue IgM test, bolus (third one with colloids) Indirect IgG ELISA test, Dengue - 15-30 minutes vital sign Rapid tests), virus isolation, detection monitoring until stable, and then of virus genetic materials (polymerase 1-2 hourly chain reaction -PCR) and detection of - twice a day monitoring for dengue virus protein (NS1 antigen). warning sign, general well being (appetite/oral intake), bleeding 4) WHO Classification for Dengue Fever symptoms, neurological/ mental a) Dengue fever state b) Dengue Hemorrhagic fever - Hourly urine output monitoring mild (grade I and II) - Daily BUSE/Creat, LFT, RBS, Dengue shock syndromes (grade III Coagulation profile, Acid base and IV) imbalance - Admit patient to Intensive care 5) Complication unit if condition worsen. Consider - Acute abdomen blood product transfusion, - Hepatitis and liver failure inotropes. - Encephalitis or encephalopathy - Dengue notification form (24H) - Hypovolumic shock, DIC