Hepatotoxicity, or liver toxicity, can result from anti-tuberculosis (TB) drugs and is known as drug-induced hepatitis (DIH). Patients at high risk include those with pre-existing liver conditions, alcohol use, and advanced TB. Monitoring of liver enzymes is important for high risk patients during TB treatment. Symptoms of DIH include fatigue, nausea, and jaundice. Diagnosis involves abnormal liver enzymes and symptom resolution after stopping anti-TB drugs. Management consists of gradual dose escalation while monitoring for toxicity.
29. Management of DIH Monitor for a fortnight. If clinically,there is no problem and LFT shows no rise, increase to full dose. Add INH in half dose Monitor for a fortnight. If clinically,there is no problem and LFT shows no rise, increase to full dose. Add PZA in half dose Monitor for a fortnight. If clinically,there is no problem and LFT shows no rise, increase to full dose. Add rifampicin in half dose Monitor LFT and wait for normalisation Start streptomycin and ethambutol Perform LFT Stop all anti-TB drugs Follow-up Action
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
This graph shows the direct correlation between the lowering of the CD4 count and the acquisition of opportunistic infections.
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
These organisms can take advantage of the âopportunityâ provided by the defective or weakened immune system that results from HIV/AIDS. The resulting illnesses are usually more severe in HIV/ AIDS patients than in people with normal immune systems. When a person is first found to be HIV positive, immunizations are given to help decrease the number of opportunistic infections. These immunizations include: Pneumovax Influenza vaccine Hepatitis B vaccine Tetanus-diphtheria
This graph shows the direct correlation between the lowering of the CD4 count and the acquisition of opportunistic infections.