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HTN new Updates Dr Ihab Suliman MBBS,ECFMG(USA),DCBNC(USA), MRCP(UK) Associate Consultant Cardiology Member of the European Working Group on Nuclear Cardiology & Cardiac CT
Case  ,[object Object]
[object Object],[object Object],[object Object]
[object Object]
HTN Defined ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Properly Measured ,[object Object],[object Object],[object Object],[object Object]
Hypertension Risk Factors ,[object Object],[object Object],[object Object],[object Object],[object Object]
Benefits of HTN Rx ,[object Object],[object Object],[object Object]
NNT ,[object Object]
Case  ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Hypertensive Urgency & Emergency ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Hypertensive Emergency Sx ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Algorithm for Treatment of Hypertension  (JNC 7)  JAMA, May 2003 Not at Goal Blood Pressure (<140/90 mmHg)  (<130/80 mmHg for those with diabetes or chronic kidney disease) Initial Drug Choices Lifestyle Modifications Drug(s) for the compelling indications  With Compelling  Indications Stage 2 Hypertension   2-drug combination for most  Stage 1 Hypertension   Thiazide-type diuretics for most.  May consider ACEI, ARB, BB, CCB, or combination Without Compelling  Indications
Case  ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
Choosing drugs for patients newly diagnosed with hypertension BHS Guidelines (June 2006) Younger than 55 years 55 years or older Or black patients  of any age A C or D A+C or A+D A+C+D ,[object Object],[object Object],[object Object],[object Object],[object Object],Abbreviations: A: ACE-I (or ARB if ACE intolerant) C: CCB D: thiazide type diuretic Step 1 Step 2 Step 3 Step 4
Hypertension and Diabetes Recommendations of the American Diabetic Association  ,[object Object],[object Object],[object Object],American Diabetes Association. Diabetes Care.  2005; 28 (Suppl 1): S10 – S17.
Conditions favoring the use of ARBs ,[object Object],[object Object],[object Object],[object Object],[object Object]
Case 1 ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
The following are Positive trials? ,[object Object],[object Object],[object Object]
The following are Positive trials? ,[object Object]
Prevalence of HTN ,[object Object],[object Object],[object Object],[object Object]
[object Object]
Case  ,[object Object],[object Object],[object Object],[object Object]
[object Object]
Scientific evidence ,[object Object],[object Object],[object Object],[object Object]
[object Object]
ALLHAT study ,[object Object],[object Object],[object Object],[object Object]
[object Object]
HERs The Heart & estrogen Replacement therapy study ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Development of new diabetes – CHARM study 0 10 20 30 40 50 60 70 80 No. of  cases  developing  new  Diabetes Control candesartan 40% p =0.005 Lancet, 2003
© 2008, American Heart Association. All rights reserved.  ,[object Object],[object Object],Resistant Hypertension
[object Object]

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Ht Nlecture2009

  • 1. HTN new Updates Dr Ihab Suliman MBBS,ECFMG(USA),DCBNC(USA), MRCP(UK) Associate Consultant Cardiology Member of the European Working Group on Nuclear Cardiology & Cardiac CT
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  • 21. Algorithm for Treatment of Hypertension (JNC 7) JAMA, May 2003 Not at Goal Blood Pressure (<140/90 mmHg) (<130/80 mmHg for those with diabetes or chronic kidney disease) Initial Drug Choices Lifestyle Modifications Drug(s) for the compelling indications With Compelling Indications Stage 2 Hypertension 2-drug combination for most Stage 1 Hypertension Thiazide-type diuretics for most. May consider ACEI, ARB, BB, CCB, or combination Without Compelling Indications
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  • 45. Development of new diabetes – CHARM study 0 10 20 30 40 50 60 70 80 No. of cases developing new Diabetes Control candesartan 40% p =0.005 Lancet, 2003
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