Glycogenolysis

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Dr. Khuram Aziz

conversion of glycogen into glucose and its regulation

Carbohydrate metabolism
GLYCOENOLYSIS

GLYCOENOLYSIS
• Break down of glycogen into glucose
• It takes place in liver ad muscles
• Key enzyme is glycogen phosphorylase

Reactions
• Shortening of chains
• Removal of branches
• Glucose-1-phosphate to G-6-Phosphate

Other pathway
• Lysosomal degradation(alpha amylosis)
• Gemma-amylosis

Regulation
• Activation of Phosphorylase
• Activation of inhibitor-1
• Role of calcium in glycogenolysis in muscles

Glycogenolysis

Glycogenolysis

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Glycogenolysis

1. Carbohydrate metabolism GLYCOENOLYSIS

2. GLYCOENOLYSIS • Break down of glycogen into glucose • It takes place in liver ad muscles • Key enzyme is glycogen phosphorylase

3. Reactions • Shortening of chains • Removal of branches • Glucose-1-phosphate to G-6-Phosphate

4.

5. Other pathway • Lysosomal degradation(alpha amylosis) • Gemma-amylosis

6. Regulation • Activation of Phosphorylase • Activation of inhibitor-1 • Role of calcium in glycogenolysis in muscles