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Elaine N. Marieb


                   The Human Body:
                    An Orientation
REQUIRED TEXTBOOK
• Anatomy &
  Physiology, 4th edition
• Marieb
• BIO 2113/2114
• Janyce
  House, Instructor
Overview of Anatomy and Physiology
• Anatomy – the structure of body parts
  – Gross or macroscopic
  – Microscopic
  – Developmental
• Physiology – the function of body parts
Microscopic Anatomy
• Cytology –
• Histology –
Physiology
• Considers the operation of specific organ
  systems
  – Renal –
  – Neurophysiology –
  – Cardiovascular –
• Focuses on the functions of the body, often at
  the cellular or molecular level
Physiology
• Understanding physiology:
• Physics
• Pathophysiology – abnormal or disease body
  function
Principle of Complementarity
• Function always reflects structure
• What a structure can do depends on its
  specific form
Levels of Structural Organization
•   Chemical –
•   Cellular –
•   Tissue –
•   Organ –
•   Organ system –
•   Organismal –
Levels of Structural Organization
               Smooth muscle cell
                                            Molecules
   2 Cellular level
     Cells are made up of molecules                   Atoms


                                                              1 Chemical level
                                                                Atoms combine to
                                        Smooth                  form molecules
                                        muscle
                                        tissue
                                                         Heart
3 Tissue level
                                    Cardiovascular
  Tissues consist of
                                           system        Blood
  similar types of cells
                                                         vessels
                                         Epithelial
                                         tissue
                                      Smooth             Blood
                                      muscle             vessel
                                      tissue             (organ)                          6 Organismal level
                            Connective                                                      The human organism is made
                            tissue                                                          up of many organ systems

             4 Organ level
               Organs are made up of different                5 Organ system level
               types of tissues                                 Organ systems consist of different organs that
                                                                work together closely
                                                                                                             Figure 1.1
Bio. 2113 - Organ Systems of the Body
                - p. 6
•   Integumentary system
•   Skeletal system
•   Muscular System
•   Nervous System
Bio. 2114 - Organ Systems of the Body
               - p. 6 &7

•   Endocrine System
•   Cardiovascular System
•   Lymphatic System/Immunity
•   Respiratory System
•   Digestive System
•   Urinary System
•   Male and Female Reproductive Systems
Organ Systems Interrelationships

• The integumentary system protects the body
  from the external environment
• Digestive and respiratory systems, in contact
  with the external environment, take in
  nutrients and oxygen
Organ Systems Interrelationships


 • Nutrients and oxygen
   are distributed by
   the blood
 • Metabolic wastes are
   eliminated by the
   urinary and
   respiratory systems

                                   Figure 1.2
Necessary Life Functions I
• Maintaining boundaries – the internal environment
  remains distinct from the external
   – Cellular level –
   – Organismal level –
• Movement – locomotion, propulsion (peristalsis), and
  contractility
• Responsiveness –
• Digestion –
Necessary Life Functions II
• Metabolism –
• Excretion –
• Reproduction –
   – Cellular – an original cell divides and produces two identical daughter
     cells
   – Organismal – sperm and egg unite to make a whole new person
• Growth –
Survival Needs

•   Nutrients –
•   Oxygen –
•   Water –
•   Maintaining normal body temperature –
•   Atmospheric pressure –
HOMEOSTASIS
• STABLE INTERNAL ENVIRONMENT.
• COMMUNICATION WITHIN THE BODY
  (NERVOUS & ENDOCRINE SYSTEMS)
Homeostatic Control Mechanisms

• CONTROL MECHANISMS FOR HOMEOSTASIS:
  – Receptor – changes (stimuli)
  – Control center – determines the set point at which
    the variable is maintained
  – Effector – responds to the stimulus
Homeostatic Control Mechanisms
          3 Input:                                 Control
                                                   center         4 Output:
            Information                                             Information sent
            sent along                                              along efferent
            afferent                                                pathway to
            pathway to



                  Receptor (sensor)                               Effector



       Change
     2 detected
       by receptor



                                                                             5 Response of
                                                                               effector feeds
                                                                               back to influence
1   Stimulus:                                                                  magnitude of
    Produces                                                                   stimulus and
    change                                                                     returns
    in variable                                                                variable to
                                                                               homeostasis
                                      Variable (in homeostasis)




                                                                                       Figure 1.4
Negative Feedback
• In negative feedback systems, the output
  shuts off the original stimulus
• Examples: Regulation of blood glucose levels;
  body temperature

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Ch 1 a

  • 1. 1 1 Elaine N. Marieb The Human Body: An Orientation
  • 2. REQUIRED TEXTBOOK • Anatomy & Physiology, 4th edition • Marieb • BIO 2113/2114 • Janyce House, Instructor
  • 3. Overview of Anatomy and Physiology • Anatomy – the structure of body parts – Gross or macroscopic – Microscopic – Developmental • Physiology – the function of body parts
  • 4. Microscopic Anatomy • Cytology – • Histology –
  • 5. Physiology • Considers the operation of specific organ systems – Renal – – Neurophysiology – – Cardiovascular – • Focuses on the functions of the body, often at the cellular or molecular level
  • 6. Physiology • Understanding physiology: • Physics • Pathophysiology – abnormal or disease body function
  • 7. Principle of Complementarity • Function always reflects structure • What a structure can do depends on its specific form
  • 8. Levels of Structural Organization • Chemical – • Cellular – • Tissue – • Organ – • Organ system – • Organismal –
  • 9. Levels of Structural Organization Smooth muscle cell Molecules 2 Cellular level Cells are made up of molecules Atoms 1 Chemical level Atoms combine to Smooth form molecules muscle tissue Heart 3 Tissue level Cardiovascular Tissues consist of system Blood similar types of cells vessels Epithelial tissue Smooth Blood muscle vessel tissue (organ) 6 Organismal level Connective The human organism is made tissue up of many organ systems 4 Organ level Organs are made up of different 5 Organ system level types of tissues Organ systems consist of different organs that work together closely Figure 1.1
  • 10. Bio. 2113 - Organ Systems of the Body - p. 6 • Integumentary system • Skeletal system • Muscular System • Nervous System
  • 11. Bio. 2114 - Organ Systems of the Body - p. 6 &7 • Endocrine System • Cardiovascular System • Lymphatic System/Immunity • Respiratory System • Digestive System • Urinary System • Male and Female Reproductive Systems
  • 12. Organ Systems Interrelationships • The integumentary system protects the body from the external environment • Digestive and respiratory systems, in contact with the external environment, take in nutrients and oxygen
  • 13. Organ Systems Interrelationships • Nutrients and oxygen are distributed by the blood • Metabolic wastes are eliminated by the urinary and respiratory systems Figure 1.2
  • 14. Necessary Life Functions I • Maintaining boundaries – the internal environment remains distinct from the external – Cellular level – – Organismal level – • Movement – locomotion, propulsion (peristalsis), and contractility • Responsiveness – • Digestion –
  • 15. Necessary Life Functions II • Metabolism – • Excretion – • Reproduction – – Cellular – an original cell divides and produces two identical daughter cells – Organismal – sperm and egg unite to make a whole new person • Growth –
  • 16. Survival Needs • Nutrients – • Oxygen – • Water – • Maintaining normal body temperature – • Atmospheric pressure –
  • 17. HOMEOSTASIS • STABLE INTERNAL ENVIRONMENT. • COMMUNICATION WITHIN THE BODY (NERVOUS & ENDOCRINE SYSTEMS)
  • 18. Homeostatic Control Mechanisms • CONTROL MECHANISMS FOR HOMEOSTASIS: – Receptor – changes (stimuli) – Control center – determines the set point at which the variable is maintained – Effector – responds to the stimulus
  • 19. Homeostatic Control Mechanisms 3 Input: Control center 4 Output: Information Information sent sent along along efferent afferent pathway to pathway to Receptor (sensor) Effector Change 2 detected by receptor 5 Response of effector feeds back to influence 1 Stimulus: magnitude of Produces stimulus and change returns in variable variable to homeostasis Variable (in homeostasis) Figure 1.4
  • 20. Negative Feedback • In negative feedback systems, the output shuts off the original stimulus • Examples: Regulation of blood glucose levels; body temperature