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HIV/AIDS
What Do You Know?
HIV/AIDS                    What Do You Know?

 What is HIV? What is AIDS?
                                     "Helping kids understand
                                       about AIDS is the most
 How is the disease transmitted?       important thing I do.
                                     Some kids like to pretend
                                      that it's not happening in
                                     the world. By letting them
 In what part of the world is        know what's really going
                                           on, I might save
  HIV/AIDS most prevalent?                someone's life."
                                          Hydeia L. Broadbent
                                        AIDS patient and activist.
 Who is vulnerable to contracting
  HIV/AIDS?
HIV/AIDS                           Terms to Know
HIV:     the Human Immunodeficiency Virus
 a retrovirus that attacks and destroys a type of white blood cell called a
  CD4 cell
 attacks the immune system – since the CD4’s main function is to fight
  disease, when a person’s CD4 cell count gets low, they are more
  susceptible to illnesses
 HIV is the virus that eventually causes AIDS
 An HIV positive test result does not mean a person has AIDS
 HIV/AIDS currently no cure


AIDS:     Acquired Immune Deficiency Syndrome
 the final stage of HIV infection.
 when the immune system CD4 cells drop to a very low level, a person's
  ability to fight infection is lost
HIV/AIDS                          Terms to Know
AIDS:       Acquired Immune Deficiency Syndrome
   the final stage of HIV infection.
   when the immune system CD4 cells drop to a very low level, a person's
    ability to fight infection is lost
   a collection of infections and cancers that people with HIV might develop
   if a person gets one of these infections or cancers after they are HIV+
    they are said to have AIDS.
   many of the infections that cause AIDS are harmless to a healthy immune
    system.

          HIV/AIDS can infect anyone
         regardless of age, race or sexual
                   preference.
HIV/AIDS                             Four Stages of HIV
     Stage 1: Primary
•    Short, flu-like illness - occurs one to six weeks
     after infection
•    no symptoms at all
•    Infected person can infect other people

     Stage 2: Asymptomatic
•    Lasts for an average of ten years
•    This stage is free from symptoms
•    There may be swollen glands
•    The level of HIV in the blood drops to very low
     levels
•    HIV antibodies are detectable in the blood
HIV/AIDS                          Four Stages of HIV
     Stage 3: Symptomatic
•    The symptoms are mild
•    The immune system deteriorates
•    Emergence of opportunistic infections and cancers

     Stage 4: HIV -> AIDS
•    The immune system weakens
•    The illnesses become more severe leading to an
     AIDS diagnosis
HIV/AIDS                     Symptoms
 Diarrhea or other bowel changes
 Fatigue
 Fever
 Loss of appetite or unexplained weight loss
 Dry cough or shortness of breath
 Night sweats
 Swollen lymph nodes in the neck, armpits, and groin
 Confusion, difficulty concentrating, or personality changes
 Repeated outbreaks of cold sores or genital herpes sores
 Tingling, numbness, and weakness in the limbs
 Mouth sores or a yeast infection of the mouth
HIV/AIDS              Opportunistic Infections
                      associated with AIDS

• Bacterial
  – Tuberculosis (TB)
  – Strep pneumonia

• Viral
  – Kaposi Sarcoma
  – Herpes
  – Influenza (flu)
HIV/AIDS            Opportunistic Infections
                    associated with AIDS

• Parasitic
  – Pneumocystis carinii

• Fungal
  – Candida
  – Cryptococcus
HIV/AIDS                      Modes of Transmission
 Exchange of bodily fluids
HIV/AIDS      Testing Options

    Anonymous Testing
    Confidential Testing

     Administration
    Blood
    Urine
    Oral
HIV/AIDS                Blood Testing
• Enzyme-Linked Immunosorbent Assay/Enzyme
  Immunoassay (ELISA/EIA)

• Radio Immunoprecipitation Assay/Indirect
  Fluorescent Antibody Assay (RIP/IFA)

• Polymerase Chain Reaction (PCR)

• Western Blot Confirmatory test
HIV/AIDS                       Urine Testing
• Urine Western Blot
   – As sensitive as testing blood
   – Safe way to screen for HIV
   – Can cause false positives in certain people at high risk for
     HIV
                         Oral
                         Testing
Orasure
  The only FDA approved HIV antibody.
  As accurate as blood testing
  Draws blood-derived fluids from the gum tissue.
  NOT A SALIVA TEST!
HIV/AIDS                    Treatment Options
Antiretroviral
Drugs
• Nucleoside Reverse
  Transcriptase inhibitors
                               Opportunistic
   – AZT (Zidovudine)          Infection
• Non-Nucleoside               Treatment
  Transcriptase inhibitors
   – Viramune (Nevirapine)
• Protease inhibitors
   – Norvir (Ritonavir)
HIV/AIDS                                Prevention
 Abstinence

 Safe/Protected Sex
    Condoms – latex or polyurethane condom (not natural skin condom)
    HIV testing before intercourse with partner
    Talk with partner/s about your and their sexual history

 Monogamy
    Reduce number of sex partners


 Sterile needles
    Do not share intravenous (IV) needles, syringes, cookers, cotton, eyedroppers, etc.
    Donate blood, plasma, semen, body organs, or body tissues to reputable medical centers

 Do not share personal items, such as toothbrushes, razors, or sex toys, that
  may be contaminated with blood, semen, or vaginal fluids.
HIV/AIDS                                   Basic Facts
 Sub-Saharan Africa                          25.8 million people living with HIV

 Asia                                        8.3 million people living with HIV

 North America, Western and Central          1.9 million people living with HIV
  Europe

 Eastern Europe and Central Asia             1.6 million people living with HIV

 Middle East and North Africa                510,000 people living with HIV

 Caribbean                                   300,000 people living with HIV

 Oceania                                     74,000 people living with HIV

 Latin America                               1.8 million people living with HIV
Source: UNAIDS AIDS Epidemic Update 2005
HIV/AIDS               2002 HIV Infections by Age Group




  Source: UNAIDS/WHO
HIV/AIDS                                                             Basic Facts
 Every minute five people around the world between the ages of 10 and 24
  are infected with HIV.

 There are 2.5 million children under the age of 15 living with the disease
  worldwide.

 In Sub-Saharan Africa, the majority of new infections occurs among
  young people between the ages of 15 and 24.

 Of the 3 million who died of AIDS in 2003, 500,000 were children.

 The total number of children orphaned by AIDS – 13.2 million as of 2001
  – is expected to more than double by 2010.
Source: UNAIDS. <www.unaids.org> (April 29, 2004).
Source: UNAIDS, “AIDS Epidemic Update: December 2003,” p.3.
Source: UNICEF, “Young People and HIV/AIDS: Opportunity in Crisis,” p.6 [publication on-line]
      www.unicef.org/publictions/pub_youngpeople_hivaids_en.pdf (February 17, 2004).
Source: UNAIDS, “AIDS Epidemic Update: December 2003,” p.3.
Source: UN Special Session on HIV/AIDS. “Fact Sheet.” 2001.
HIV/AIDS




  Source: UNAIDS/WHO
HIV/AIDS                                 Recap and
Discussion
                                      How can HIV/AIDS be transmitted? How
“Care for us and accept us –           do children contract HIV?
  we are all human beings.
  We are normal. We have
 hands. We have feet. We              Who is most vulnerable?
  can walk, we can talk, we
     have needs just live             How can you prevent yourself from
  everyone else – don’t be             contracting HIV?
 afraid of us – we are all the
            same!”
                                      How do you think people would react if
         Nkosi Johnson                 you had HIV/AIDS?
  13 International AIDS Conference
    th
HIV/AIDS                           What Can You Do?
 Educate yourself about HIV/AIDS.

 Contact local, state, and national
  politicians for support for HIV/AIDS.
    Write letters asking for their opinion on
     HIV/AIDS.

 Talk to your parents about HIV/AIDS.
    Educate the adults in your life!


 Advocate for HIV/AIDS awareness!
    Begin a social awareness/human rights club.
HIV/AIDS                      For More Information
AIDS.org                            UNAIDS
www.aids.org                        www.unaids.org

Center for Disease Control          UNICEF
www.cdc.gov                         www.unicef.org/aids

AIDS Alliance for Children, Youth   Youth Advocate Program
& Families                          International
www.aids-alliance.org               www.yapi.org
Population Services International
www.youthaids.org

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HIV/AIDS

  • 2. HIV/AIDS What Do You Know?  What is HIV? What is AIDS? "Helping kids understand about AIDS is the most  How is the disease transmitted? important thing I do. Some kids like to pretend that it's not happening in the world. By letting them  In what part of the world is know what's really going on, I might save HIV/AIDS most prevalent? someone's life." Hydeia L. Broadbent AIDS patient and activist.  Who is vulnerable to contracting HIV/AIDS?
  • 3. HIV/AIDS Terms to Know HIV: the Human Immunodeficiency Virus  a retrovirus that attacks and destroys a type of white blood cell called a CD4 cell  attacks the immune system – since the CD4’s main function is to fight disease, when a person’s CD4 cell count gets low, they are more susceptible to illnesses  HIV is the virus that eventually causes AIDS  An HIV positive test result does not mean a person has AIDS  HIV/AIDS currently no cure AIDS: Acquired Immune Deficiency Syndrome  the final stage of HIV infection.  when the immune system CD4 cells drop to a very low level, a person's ability to fight infection is lost
  • 4. HIV/AIDS Terms to Know AIDS: Acquired Immune Deficiency Syndrome  the final stage of HIV infection.  when the immune system CD4 cells drop to a very low level, a person's ability to fight infection is lost  a collection of infections and cancers that people with HIV might develop  if a person gets one of these infections or cancers after they are HIV+ they are said to have AIDS.  many of the infections that cause AIDS are harmless to a healthy immune system. HIV/AIDS can infect anyone regardless of age, race or sexual preference.
  • 5. HIV/AIDS Four Stages of HIV  Stage 1: Primary • Short, flu-like illness - occurs one to six weeks after infection • no symptoms at all • Infected person can infect other people  Stage 2: Asymptomatic • Lasts for an average of ten years • This stage is free from symptoms • There may be swollen glands • The level of HIV in the blood drops to very low levels • HIV antibodies are detectable in the blood
  • 6. HIV/AIDS Four Stages of HIV  Stage 3: Symptomatic • The symptoms are mild • The immune system deteriorates • Emergence of opportunistic infections and cancers  Stage 4: HIV -> AIDS • The immune system weakens • The illnesses become more severe leading to an AIDS diagnosis
  • 7. HIV/AIDS Symptoms  Diarrhea or other bowel changes  Fatigue  Fever  Loss of appetite or unexplained weight loss  Dry cough or shortness of breath  Night sweats  Swollen lymph nodes in the neck, armpits, and groin  Confusion, difficulty concentrating, or personality changes  Repeated outbreaks of cold sores or genital herpes sores  Tingling, numbness, and weakness in the limbs  Mouth sores or a yeast infection of the mouth
  • 8.
  • 9. HIV/AIDS Opportunistic Infections associated with AIDS • Bacterial – Tuberculosis (TB) – Strep pneumonia • Viral – Kaposi Sarcoma – Herpes – Influenza (flu)
  • 10. HIV/AIDS Opportunistic Infections associated with AIDS • Parasitic – Pneumocystis carinii • Fungal – Candida – Cryptococcus
  • 11. HIV/AIDS Modes of Transmission  Exchange of bodily fluids
  • 12. HIV/AIDS Testing Options Anonymous Testing Confidential Testing Administration Blood Urine Oral
  • 13. HIV/AIDS Blood Testing • Enzyme-Linked Immunosorbent Assay/Enzyme Immunoassay (ELISA/EIA) • Radio Immunoprecipitation Assay/Indirect Fluorescent Antibody Assay (RIP/IFA) • Polymerase Chain Reaction (PCR) • Western Blot Confirmatory test
  • 14. HIV/AIDS Urine Testing • Urine Western Blot – As sensitive as testing blood – Safe way to screen for HIV – Can cause false positives in certain people at high risk for HIV Oral Testing Orasure The only FDA approved HIV antibody. As accurate as blood testing Draws blood-derived fluids from the gum tissue. NOT A SALIVA TEST!
  • 15. HIV/AIDS Treatment Options Antiretroviral Drugs • Nucleoside Reverse Transcriptase inhibitors Opportunistic – AZT (Zidovudine) Infection • Non-Nucleoside Treatment Transcriptase inhibitors – Viramune (Nevirapine) • Protease inhibitors – Norvir (Ritonavir)
  • 16. HIV/AIDS Prevention  Abstinence  Safe/Protected Sex  Condoms – latex or polyurethane condom (not natural skin condom)  HIV testing before intercourse with partner  Talk with partner/s about your and their sexual history  Monogamy  Reduce number of sex partners  Sterile needles  Do not share intravenous (IV) needles, syringes, cookers, cotton, eyedroppers, etc.  Donate blood, plasma, semen, body organs, or body tissues to reputable medical centers  Do not share personal items, such as toothbrushes, razors, or sex toys, that may be contaminated with blood, semen, or vaginal fluids.
  • 17. HIV/AIDS Basic Facts  Sub-Saharan Africa 25.8 million people living with HIV  Asia 8.3 million people living with HIV  North America, Western and Central 1.9 million people living with HIV Europe  Eastern Europe and Central Asia 1.6 million people living with HIV  Middle East and North Africa 510,000 people living with HIV  Caribbean 300,000 people living with HIV  Oceania 74,000 people living with HIV  Latin America 1.8 million people living with HIV Source: UNAIDS AIDS Epidemic Update 2005
  • 18. HIV/AIDS 2002 HIV Infections by Age Group Source: UNAIDS/WHO
  • 19. HIV/AIDS Basic Facts  Every minute five people around the world between the ages of 10 and 24 are infected with HIV.  There are 2.5 million children under the age of 15 living with the disease worldwide.  In Sub-Saharan Africa, the majority of new infections occurs among young people between the ages of 15 and 24.  Of the 3 million who died of AIDS in 2003, 500,000 were children.  The total number of children orphaned by AIDS – 13.2 million as of 2001 – is expected to more than double by 2010. Source: UNAIDS. <www.unaids.org> (April 29, 2004). Source: UNAIDS, “AIDS Epidemic Update: December 2003,” p.3. Source: UNICEF, “Young People and HIV/AIDS: Opportunity in Crisis,” p.6 [publication on-line] www.unicef.org/publictions/pub_youngpeople_hivaids_en.pdf (February 17, 2004). Source: UNAIDS, “AIDS Epidemic Update: December 2003,” p.3. Source: UN Special Session on HIV/AIDS. “Fact Sheet.” 2001.
  • 20. HIV/AIDS Source: UNAIDS/WHO
  • 21. HIV/AIDS Recap and Discussion  How can HIV/AIDS be transmitted? How “Care for us and accept us – do children contract HIV? we are all human beings. We are normal. We have hands. We have feet. We  Who is most vulnerable? can walk, we can talk, we have needs just live  How can you prevent yourself from everyone else – don’t be contracting HIV? afraid of us – we are all the same!”  How do you think people would react if Nkosi Johnson you had HIV/AIDS? 13 International AIDS Conference th
  • 22. HIV/AIDS What Can You Do?  Educate yourself about HIV/AIDS.  Contact local, state, and national politicians for support for HIV/AIDS.  Write letters asking for their opinion on HIV/AIDS.  Talk to your parents about HIV/AIDS.  Educate the adults in your life!  Advocate for HIV/AIDS awareness!  Begin a social awareness/human rights club.
  • 23. HIV/AIDS For More Information AIDS.org UNAIDS www.aids.org www.unaids.org Center for Disease Control UNICEF www.cdc.gov www.unicef.org/aids AIDS Alliance for Children, Youth Youth Advocate Program & Families International www.aids-alliance.org www.yapi.org Population Services International www.youthaids.org