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Publication # 31




   Gestational Diabetes


Pennington Biomedical Research Center
            Division of Education
Gestational Diabetes
 This diagnosis is given when a woman, who has never had diabetes
  before, gets diabetes or has high blood sugar, when she is pregnant.
 Its medical name is gestational diabetes mellitus or GDM.
 It is one of the most common health problems for pregnant women.
 The word “gestational” actually refers to “during pregnancy.”




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Gestational Diabetes

 It occurs in about 5% of all pregnancies,
   which is around 200,000 cases each year.

 If not treated, gestational diabetes can cause
   health problems for the mother and the fetus.




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Why didn’t I have diabetes before?

 During pregnancy, many physiological
   changes take place. Changes in metabolism
   can be seen. Insulin may not be as effective in
   moving sugar into the cells during pregnancy.
   Therefore, the cells can’t get the sugar they
   need for energy. Increased sugar levels in the
   blood can lead to many problems.




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Why isn’t insulin doing its job?

 The placenta is a system of vessels that passes
  nutrients, blood, and water from mother to fetus.
 The placenta makes certain hormones that may
  prevent insulin from working the way that it should.
 When this condition happens, it is referred to as
      insulin resistance.
 In order to keep metabolism normal during
  pregnancy, the body has to make three times
   more insulin than normal to offset the hormones
  made by the placenta.



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Why isn’t insulin doing its job?

 For most women, the body’s extra insulin
  is enough to keep their blood sugar
  levels in the healthy range.
 But, for about 5% of pregnant women,
  even the extra insulin is not enough to
  keep blood sugar levels normal.
 These women end up with high blood
  sugar or gestational diabetes at around
  the 20th to 24th week of pregnancy.




                                 PBRC 2009   6 of 44
A Treatment Plan for GDM
                       May include these items:
 Knowing your blood sugar (glucose) level and keeping it under control


 Eating a healthy diet, as outlined by your health care provider


 Getting regular, moderate physical activity


 Maintaining a healthy weight gain


 Keeping daily records of your diet, physical activity, and glucose levels


 Taking insulin and/or other medications as prescribed


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Know your blood sugar level
     & keep it under control: Overview
 There are two parts:
       Knowing your blood sugar level
          Test to see how much glucose is in your blood

       Keeping your blood sugar level under control
          Keep the amount within a healthy range at all times




 This is important to do because your blood sugar levels
  change throughout the day based on what foods you eat,
  when you eat them, and how much you eat.
 Your level of physical activity and when you do physical activity
  also influences blood sugar levels.



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Know your blood sugar level
           & keep it under control
                                            Measuring your blood             For example
 Knowing your glucose levels at              sugar will give you
                                             information about…
  specific times of the day may
                                             The amount of food      Can you have that extra ½
  become very important if insulin               you can eat         bagel for breakfast?
  therapy becomes necessary.
                                              Foods that affect      Does your body process
 Insulin resistance can increase             your glucose level     different foods differently?
  as a pregnancy progresses
                                                                     You might have high blood
  indicating a need for additional                                   sugar in the morning after
                                               Times when your
  insulin to control glucose levels.         glucose level is high
                                                                     breakfast; other women
                                                                      may have high blood sugar
                                                    or low
                                                                     after dinner.
                                                                    Does walking for 20 minutes
                                             Times that physical    after breakfast or dinner help
                                            activity is more likely to keep your glucose level
                                                                    within the healthy range?
                                             to keep your glucose
                                                level in target
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Know your blood sugar level
         & keep it under control
    You may have to test four times a day:

    1.   In the morning before eating breakfast,
          referred to as the Fasting glucose level
    2.   1 or 2 hours after breakfast
    3.   1 or 2 hours after lunch
    4.   1 or 2 hours after dinner

    You may also have to test your glucose level before you go to bed at night.
     This is referred to as your nighttime or nocturnal glucose test.




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Know your blood sugar level
         & keep it under control

 Although your glucose levels                  Time of      Healthy Target Levels
   change during the day, there is           Blood Sugar                 (in mg/dl)
   a healthy range that is normal.               Test
   If your glucose level is outside             Fasting      No higher than 95
   of the healthy target range,              glucose level
   speak with your health care
   provider.
                                              One hour       No higher than 140
                                             after eating



                                              Two hours      No higher than 120
                                             after eating

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Eating a healthy diet
                                 Overview


 A healthy diet is one that includes
          a balance of foods from all
  the food groups, giving the
  nutrients, vitamins, and minerals
  necessary             for a healthy
  pregnancy.
 For women with gestational
  diabetes, a healthy diet can help to
  keep blood sugar levels in the
  healthy target range.
 Carbohydrates are often the center
  of a healthy diet for a woman with
  gestational diabetes.
                                  PBRC 2009   12 of 44
Eating a healthy diet
                                 Carbohydrates
 Carbohydrates are nutrients which come from
     foods like grain products, fruits, and vegetables.
 During digestion, the body is able to break down
        most carbohydrates into simple sugars, like
  glucose.
 Eating carbohydrates affects blood sugar levels.
  Eating a large amount of carbohydrates at a meal
  will have a larger effect on blood glucose levels
  than eating a small amount of carbohydrates.
 It is important to balance between eating enough
  carbohydrates to receive the necessary amounts
  of energy and resultant glucose, and not
  consuming too much to where blood sugar
   levels are out of control.


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                                    PBRC 2009
Eating a healthy diet
                  Meal Plans

               With this meal plan, the number of grams of
               carbohydrates that is eaten at each meal or snack is
               counted to make sure that they are within a certain
Carbohydrate   range. A meal plan may be very specific, allowing a
  counting     specified amount at each meal or snack, or it may be
               more general, with a daily carbohydrate total.

               The exchange system groups each food consumed
               into one of the following food groups:
               bread/starches, fruits, vegetables, proteins, milk, and
The exchange   fats. Each food within a group has very similar
   system      amounts of carbohydrate, fat, protein, and calories,
               but the amounts of vitamins and minerals may vary.
               In this plan, the number of items from a food group
               that is eaten at each meal is counted. There is a
               designated amount for each group every day.


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Eating a healthy diet
               to keep blood sugar in check:


Eat meals and snacks on     Researchers recommend that women with gestational diabetes
                            should eat at least three small-to-medium sized meals and two
     a regular schedule     to four snacks every day.
           throughout the
            day

Eat smaller amounts of      It is preferable to eat several small meals every day rather than
                            one large meal. Carbohydrates will increase blood glucose level
   carbohydrates at each    directly, therefore, eating a small amount of carbohydrates all
           meal             through the day will help keep blood sugar from rising too high.



Add a nighttime snack to    A snack of one or two servings of carbohydrates before bedtime
                            will keep blood sugar at a healthy level during sleep. Some
           your meal plan   healthy examples could include: a piece of fruit, a handful of
                            pretzels, or crackers.

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Role of physical activity
 Women with gestational diabetes often
   need regular, moderate physical activity to
   help control their blood sugar levels by
   allowing insulin to work better.               Keep in mind that it
                                                 may take 2 to 4 weeks
                                                    before physical
 Examples include:                              activity has an effect
    Walking                                     on blood sugar levels.

    Prenatal aerobics classes
    Swimming


 However, a consultation and approval by a
   health care provider is needed before
   beginning any physical activity during
   pregnancy.

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                                     PBRC 2009
Role of moderate physical activity
                                How do I do it?
 Researchers are uncertain about the exact
  amount of physical activity required to control
  blood sugar during gestational diabetes.
 The amount that is usually recommended is
  based on how active an individual was before
  the pregnancy and whether or not there are
  any other health concerns.
 For some women with GDM, regular physical
  activity can include walking, swimming, or light
  running; whereas, for other women only slow
  walking may be recommended.
 A health care provider can offer advice on
  appropriate activities, and their duration and
  frequency to assure a healthy pregnancy.




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Role of moderate physical activity
               General Guidelines For Physical Activity

                    Do                                             Don’t
Participate in moderate and                     Get too tired while working out
 regular physical activity unless prohibited               or doing physical activity
          by a health care provider
Choose activities like swimming,                 Do any activity while lying on your back
  that don’t require a lot of                  when you are in your 2nd or 3rd trimester
             standing or balance                                  of pregnancy
 Wear loose, light clothing that won’t cause     Perform activities in very hot weather
excessive sweating or increased
               body temperature
  Drink a lot of water before, during, and       Perform activities that may bump or hurt
              after your activity               your belly, or that may cause you to
                                                                lose your balance
Eat a healthy diet and gain the                   Fast (skip meals) or do physical activity
           right amount of weight                            when you are hungry

Watch your level of exertion                                Over-exert yourself
          (Can you talk easily?)
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Maintain a healthy weight
                                 Overview


 Healthy weight gain can refer to your
   overall weight gain or your weekly rate
   of weight gain.

 Some health care providers focus only on
   overall gain or only on weekly gain, but some
   keep track of both types of weight gain.




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Maintain a healthy weight
                                 Overall Weight Gain Goals
                       Height                        Weight Status Category
                Feet        Inches        A                 B        C           D
                 4              9     92 or less       93-113      114-134   135 or more
                 4              10    94 or less       95-117      118-138   139 or more
                 4              11    97 or less       98-120      121-142   143 or more
                 5              0    100 or less       101-123     124-146   147 or more
                 5              1    103 or less       104-127     128-150   151 or more
                 5              2    106 or less       107-131     132-155   156 or more
                 5              3    109 or less       110-134     135-159   160 or more
                 5              4    113 or less       114-140     141-165   166 or more
                 5              5    117 or less       118-144     145-170   171 or more
                 5              6    121 or less       122-149     150-176   177 or more
                 5              7    124 or less       125-153     154-181   182 or more
                 5              8    128 or less       129-157     158-186   187 or more
                 5              9    131 or less       132-162     163-191   192 or more
Your overall     5              10   135 or less       136-166     167-196   197 or more
 weight gain     5              11   139 or less       140-171     172-202   203 or more
goal for the
                 6              0    142 or less       143-175     176-207   208 or more
pregnancy is:                                  PBRC 2009                                   20 of 44

                                        35-40              30-35   22-27       15-20
Maintain a healthy weight
                    Weekly Rate Of Weight Gain

              Time Frame                                  Expected Weight Gain

  In the first trimester of pregnancy              Three to six pounds for the
          (the first 3 months)                               entire three months


 During the second and third trimester                Between ½ and 1 pound each week
           (the last 6 months)

If you gained too much weight early in the        Limit weight gain to ¾ of a pound each week
                pregnancy                           (3 pounds each month) to help get your
                                                         blood sugar level under control




                         A weight gain of two pounds or more each
                                                    week is considered
                                              high.
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Maintain a healthy weight
                        Things to Keep in Mind
1.   A weekly rate of weight gain may go up and
     down throughout the pregnancy.
2.   A physician can assess whether weight gain
     is appropriate or not.
3.   A weight loss can be dangerous during any
     part of the pregnancy, therefore any weight
     loss needs to be reported to a health care
     provider right away.
4.   If weight gain slows or stop, and does not
     increase again after one-to-two weeks, it
     should be reported to a health care provider
     immediately. Adjustments in your treatment
     plan may be necessary.



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Maintain a healthy weight
                                 Additional tips

   Try to get more light or moderate                  Use spices and herbs
    physical activity, if your health care
                                                        (such as curry, garlic,
    provider says that it is safe.
                                                            and parsley) and low-fat
                                                               or lower calorie sauces
   Use the Nutrition Facts labels on food                      to flavor rice and pasta.
    packages to make lower-calorie food
    choices that fit into a healthy meal plan.         Eat smaller meals and
                                                        have low-calorie snacks
   Eat fewer fried foods and “fast” foods.              more often, to ensure that your body has
                                                        a constant glucose supply, and to prevent
   Eat healthy foods that fit into your meal           yourself from getting very hungry.
    plan, such as salads with low-fat
    dressings and broiled or grilled chicken.          Avoid skipping meals or cutting back too
                                                        much on breakfast or lunch. Eating less
   Use less butter and margarine on food,              food or skipping meals could make you
    or don’t use them at all.                           overly hungry at the next meal, causing
                                                        you to overeat.


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Keep daily records of your diet,
 physical activity, and glucose levels

 Keeping records refers to writing down your blood sugar numbers, physical
   activities, and everything that you eat and drink in a daily record book.

 Recording everything that you eat and drink really means everything that you
   eat and drink. This refers to bites, nibbles, snacks, second helpings, and all
   liquids.

 It’s easy to forget or underestimate how much snacking you really do.




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Keep daily records of your diet,
   physical activity, and glucose levels
 Your health care provider might ask that you keep track of the following:

       Blood sugar level

       Food

       Physical wellness

       Physical activity

       Weight gain


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Keep daily records of your diet,
  physical activity, and glucose levels
 It’s a good idea to follow a schedule for
   writing in the record book.

 This lets you get used to writing in it and
   helps you to remember to do it.

 Daily records help to keep track of how
   well your treatment plan is working and
   what, if anything, should be changed.

 The information also reveals whether or
   not you will need insulin, and if so, how
   much will be needed.
                                     PBRC 2009   26 of 44
Take insulin and/or
     other medications as prescribed

 Even if you do everything your health care provider
   recommends to manage your gestational diabetes, you
   may still need to take insulin during your pregnancy to
   keep it under control.

 The only way to get extra insulin into your body is to
   inject it under your skin with a needle.




                                    PBRC 2009                27 of 44
Take insulin and/or
     other medications as prescribed
 You may have to include small amounts of insulin in your treatment plan if:


       Your blood sugar level is too high

       Your blood sugar level is frequently too high

       Your blood sugar level remains high, and you are not gaining
        much weight even with proper eating habits

       You cannot safely add physical activity to your treatment plan




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Take insulin and/or
    other medications as prescribed
    Things to know about insulin:

    1.   If you need to take insulin, it does not mean that you didn’t try hard
         enough or that you failed at taking care of yourself.

    2.   Taking insulin does not mean that you have Type 1 diabetes.

    3.   An increase in the amount or dosage of insulin needed does not mean
         that your pregnancy is in danger.

    4.   You may need more insulin if you are under high amounts of stress or if
         you are sick because your blood sugar level gets higher on its own in
         these cases.

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Take insulin and/or
     other medications as prescribed
 Special instructions for women taking insulin are to:


       Follow a regular eating schedule
          The timing of insulin shots and of eating meals needs to be correct. Your

             healthcare provider can tell you when to do both. It is very important not
             to skip or delay meals and snacks when taking insulin because this can
             affect your glucose-insulin balance.

       Know the symptoms of hypoglycemia
          If your blood sugar level drops below 60 at any time, you have

           hypoglycemia. This can be very dangerous. Hypoglycemia is already
           common in all women with gestational diabetes, but for women taking
           insulin for this condition, they are at greater risk.
  * Before any physical activity is begun, you should test your blood sugar. If it is low, do not
                                            PBRC 2009                                               30 of 44
  begin the activity. Eat something and test again to make sure it is higher before beginning.
Take insulin and/or
    other medications as prescribed

Why does low blood sugar occur?               How might I feel if I have low
                                                           blood sugar?
 Too much exercise
                                               Very hungry
 Skipping meals or snacks                     Very tired
                                               Shaky or trembling
 Delaying meals or snacks                     Sweating or clamminess
                                               Nervous
 Not eating enough                            Confused
                                               Like you’re going to pass out or faint
 Too much insulin                             Blurred vision



       * Report any abnormal blood sugar level to your health care provider
       right away, in case a change in your treatment plan is needed.
                                     PBRC 2009                                     31 of 44
Will GDM hurt my baby?

 Most women with gestational diabetes give
   birth to healthy babies; this is especially true
   for women who have kept their blood sugar
   under control, maintained a healthy diet,
   engaged in regular, moderate physical
   activity, and had a healthy weight
   throughout the pregnancy.

 In some cases, however, the condition can
   affect the pregnancy.




                                     PBRC 2009        32 of 44
Gestational Diabetes Mellitus
                         Associated Conditions

Macrosomia         In this condition, the baby’s body is larger than normal. Large-bodied babies may
                   be injured during natural delivery through the vagina, so the baby may need to be
                   delivered through cesarean section.

Hypoglycemia       In this condition, the baby’s blood glucose is too low. Breastfeeding may need to
                   be started right away to get more glucose into the baby’s system. If breastfeeding
                   is not possible, then the baby may need to get glucose put directly into the blood
                   through a thin, plastic tube in his or her arm.
Jaundice           In this condition ,the baby’s skin turns yellowish. The white parts of the eye may
                   also change color slightly. If treated, this is not a serious problem.
Respiratory        In this condition, the baby has trouble breathing. The baby may need oxygen or
Distress           other help breathing if he or she has this condition.
Syndrome (RDS)
Low Calcium and    In this condition, spasms in the hands and feet, or twitching and cramping of
Magnesium Levels   muscles can occur. The condition can be treated through supplementation with
in Baby’s Blood    magnesium and calcium supplements.

      Keep in mind that just because you have gestational diabetes,
                              it does PBRCmean that these problems will occur.
                                      not 2009                                                33 of 44
Could GDM hurt my baby in other
               ways?
 Gestational diabetes usually does not cause
  birth defects or deformities.
 Most developmental or physical defects
  happen during the first trimester of
  pregnancy, between the 1st and 8th week, and
  gestational diabetes typically develops
  around the 24th week of pregnancy.
 Therefore, women with gestational diabetes
  typically have normal blood sugar levels
  during the first trimester, allowing the body
  and body systems of the fetus to develop
  normally.



                                  PBRC 2009       34 of 44
Could GDM hurt my baby in other
ways?
 The fact that you have gestational diabetes will
  not cause diabetes in your baby.
 However, your child will be at a higher risk for
  developing type 2 diabetes in adulthood and
  may get it at a younger age (younger than 30).
 As your child grows, taking steps such as:
  eating a healthy diet, maintaining a healthy
  weight, and getting regular, moderate physical
  activity can help to reduce his or her risk.
 Macrosomic, or large-bodied babies are at
  higher risk for childhood and adult obesity.




                                  PBRC 2009          35 of 44
Things to keep in mind about delivery
                      If you have gestational diabetes
Blood Sugar and   Keeping blood sugar levels under control during labor and delivery is vital for both
Insulin Balance   you and your baby’s health. If you did not have to take insulin during the
                  pregnancy, then you won’t need it during labor or delivery; however, if you did have
                  to take insulin during pregnancy, then you may receive an insulin shot when labor
                  begins or during labor.
Early Delivery    Gestational diabetes puts women at higher risk for a condition known as
                  preeclampsia late in pregnancy. Preeclampsia is a condition associated with
                  sudden blood pressure increases, which can be quite serious. Unfortunately, the
                  only cure to preeclampsia is delivery of the baby, but delivery may not be the best
                  option for your health or for the health of your baby. Your health care provider will
                  keep you under close watch if this condition develops, determining whether early
                  delivery is safe and needed.

Cesarean          This is a type of delivery used to deliver the baby, as opposed to natural delivery
Delivery          through the vagina. Cesarean delivery is also referred to as a cesarean section, or
                  “C” section. Simply having gestational diabetes is not reason alone to have a
                  C section, but your health care provider may have other reasons for choosing this
                  option, such as changes in your health or your baby’s health during delivery.

                                         PBRC 2009                                              36 of 44
Will I have diabetes after having my
                  baby?
 Shortly after the baby is born, the placenta
     is “delivered.”
 Since the placenta is what was causing the
  insulin resistance, when it is gone,
  gestational diabetes usually resolves as well.
 Just by having had gestational diabetes, you
  have a 40% higher chance of developing
  type 2 diabetes later in life than women who
  did not have the condition during pregnancy.
 Keeping your weight within a healthy range
  and keeping up regular, moderate physical
  activity after your baby is born can help lower
  your risk for developing type 2 diabetes.



                                   PBRC 2009        37 of 44
What should I do after delivery?
 Six weeks after your baby is born,
   you should have a blood test to find        If your category is…        You should…

   out whether your blood sugar level                                 Get checked for
   is back to normal.                                Normal           diabetes every 3 years

                                                                      Get checked for
 Based on the results you will fall                                  diabetes every year,
   into one of the three categories:            Impaired Glucose
                                                                      and talk with your
                                                                      health care provider to
                                                   Tolerance          learn about ways to
                                                                      lower your risk for
                                                                      developing diabetes.

                                                                      Work with your health
                                                    Diabetic          care provider in setting
                                                                      up a treatment plan for
                                                                      your diabetes.

                                   PBRC 2009                                          38 of 44
Importance of checking often

 Getting checked for diabetes is important
  because Type 2 diabetes shows few symptoms.
 The only way to know for sure is to have a
  blood test that reveals a higher-than-normal
  blood sugar level.
 If you notice any of these things, you should tell
  your health care provider right away:
     Being very thirsty
     Urinating often
     Feeling constantly or overly tired
     Losing weight quickly and/or without reason




                                   PBRC 2009           39 of 44
Will I develop Type 2 diabetes in the
                     future?
          There are certain traits which increase the chances:


1. You developed gestational diabetes before your 24th week of pregnancy.
2. Your blood sugar level during pregnancy was consistently on the high end of
     the healthy range.
3.   Your blood sugar levels after the baby was born were higher-than-average,
     according to your health care provider.
4.   You are in the impaired glucose tolerance category.
5.   You are obese, according to your health care provider.
6.   You have diabetes in your family.
7.   You belong to a high-risk ethnic group (Hispanic, African American, Native
     American, South or East Asian, Pacific Islander, Indigenous Australian).
8.   You have had gestational diabetes with other pregnancies.


                                                    With one or more of these traits, you
                                                    should talk to your doctor about Type
                                    PBRC 2009                     2 diabetes.     40 of 44
Should I breastfeed having gestational
                   diabetes?
 Yes, women with gestational diabetes should
    breastfeed their babies, if possible.
   Breastfeeding is not only beneficial to the baby,
      but it is also beneficial to the mother.
   Breastfeeding allows the body to use extra calories
    stored during pregnancy, allowing for weight loss.
   A weight loss after having the baby not only enhances
    overall health, but also helps to reduce the risk of
    developing type 2 diabetes later in life.
   Breastfeeding is also believed to help lower fasting
    blood glucose levels in mothers.




                                  PBRC 2009                 41 of 44
Heli J. Roy, PhD, RD
Shanna Lundy, BS
Division of Education
Phillip Brantley, PhD, Director
Pennington Biomedical Research Center
Steven Heymsfield, MD, Executive Director




        Division of Education
About Our Company
   Pennington Biomedical Research Center
   VISION
   Our vision is to lead the world in eliminating chronic diseases.

   MISSION
   Our mission is to discover the triggers of chronic diseases through innovative research that improves human health across the lifespan. We
    are helping people live Well Beyond the Expected.
   The Pennington Center has several research areas, including:
   Clinical Obesity Research
   Experimental Obesity
   Functional Foods
   Health and Performance Enhancement
   Nutrition and Chronic Diseases
   Nutrition and the Brain
   Dementia, Alzheimer’s and healthy aging
   Diet, exercise, weight loss and weight loss maintenance
   The research fostered in these areas can have a profound impact on healthy living and on the prevention of common chronic diseases, such
    as heart disease, cancer, diabetes, hypertension and osteoporosis.
   The Division of Education provides education and information to the scientific community and the public about research findings, training
    programs and research areas, and coordinates educational events for the public on various health issues.
   We invite people of all ages and backgrounds to participate in the exciting research studies being conducted at the Pennington Center in
    Baton Rouge, Louisiana. If you would like to take part, visit the clinical trials web page at www.pbrc.edu or call (225) 763-3000.




                                                                PBRC 2009                                                               43 of 44
Sites
 All diabetes-related information is from the National Institute of Child Health
   and Human Development. Available at:
   http://www.nichd.nih.gov/publications/pubs/gdm/index.htm




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Gestational diabetes

  • 1. Publication # 31 Gestational Diabetes Pennington Biomedical Research Center Division of Education
  • 2. Gestational Diabetes  This diagnosis is given when a woman, who has never had diabetes before, gets diabetes or has high blood sugar, when she is pregnant.  Its medical name is gestational diabetes mellitus or GDM.  It is one of the most common health problems for pregnant women.  The word “gestational” actually refers to “during pregnancy.” PBRC 2009 2 of 44
  • 3. Gestational Diabetes  It occurs in about 5% of all pregnancies, which is around 200,000 cases each year.  If not treated, gestational diabetes can cause health problems for the mother and the fetus. PBRC 2009 3 of 44
  • 4. Why didn’t I have diabetes before?  During pregnancy, many physiological changes take place. Changes in metabolism can be seen. Insulin may not be as effective in moving sugar into the cells during pregnancy. Therefore, the cells can’t get the sugar they need for energy. Increased sugar levels in the blood can lead to many problems. PBRC 2009 4 of 44
  • 5. Why isn’t insulin doing its job?  The placenta is a system of vessels that passes nutrients, blood, and water from mother to fetus.  The placenta makes certain hormones that may prevent insulin from working the way that it should.  When this condition happens, it is referred to as insulin resistance.  In order to keep metabolism normal during pregnancy, the body has to make three times more insulin than normal to offset the hormones made by the placenta. PBRC 2009 5 of 44
  • 6. Why isn’t insulin doing its job?  For most women, the body’s extra insulin is enough to keep their blood sugar levels in the healthy range.  But, for about 5% of pregnant women, even the extra insulin is not enough to keep blood sugar levels normal.  These women end up with high blood sugar or gestational diabetes at around the 20th to 24th week of pregnancy. PBRC 2009 6 of 44
  • 7. A Treatment Plan for GDM May include these items:  Knowing your blood sugar (glucose) level and keeping it under control  Eating a healthy diet, as outlined by your health care provider  Getting regular, moderate physical activity  Maintaining a healthy weight gain  Keeping daily records of your diet, physical activity, and glucose levels  Taking insulin and/or other medications as prescribed PBRC 2009 7 of 44
  • 8. Know your blood sugar level & keep it under control: Overview  There are two parts:  Knowing your blood sugar level  Test to see how much glucose is in your blood  Keeping your blood sugar level under control  Keep the amount within a healthy range at all times  This is important to do because your blood sugar levels change throughout the day based on what foods you eat, when you eat them, and how much you eat.  Your level of physical activity and when you do physical activity also influences blood sugar levels. PBRC 2009 8 of 44
  • 9. Know your blood sugar level & keep it under control Measuring your blood For example  Knowing your glucose levels at sugar will give you information about… specific times of the day may The amount of food Can you have that extra ½ become very important if insulin you can eat bagel for breakfast? therapy becomes necessary. Foods that affect Does your body process  Insulin resistance can increase your glucose level different foods differently? as a pregnancy progresses You might have high blood indicating a need for additional sugar in the morning after Times when your insulin to control glucose levels. glucose level is high breakfast; other women may have high blood sugar or low after dinner. Does walking for 20 minutes Times that physical after breakfast or dinner help activity is more likely to keep your glucose level within the healthy range? to keep your glucose level in target PBRC 2009 9 of 44
  • 10. Know your blood sugar level & keep it under control  You may have to test four times a day: 1. In the morning before eating breakfast, referred to as the Fasting glucose level 2. 1 or 2 hours after breakfast 3. 1 or 2 hours after lunch 4. 1 or 2 hours after dinner  You may also have to test your glucose level before you go to bed at night. This is referred to as your nighttime or nocturnal glucose test. PBRC 2009 10 of 44
  • 11. Know your blood sugar level & keep it under control  Although your glucose levels Time of Healthy Target Levels change during the day, there is Blood Sugar (in mg/dl) a healthy range that is normal. Test If your glucose level is outside Fasting No higher than 95 of the healthy target range, glucose level speak with your health care provider. One hour No higher than 140 after eating Two hours No higher than 120 after eating PBRC 2009 11 of 44
  • 12. Eating a healthy diet Overview  A healthy diet is one that includes a balance of foods from all the food groups, giving the nutrients, vitamins, and minerals necessary for a healthy pregnancy.  For women with gestational diabetes, a healthy diet can help to keep blood sugar levels in the healthy target range.  Carbohydrates are often the center of a healthy diet for a woman with gestational diabetes. PBRC 2009 12 of 44
  • 13. Eating a healthy diet Carbohydrates  Carbohydrates are nutrients which come from foods like grain products, fruits, and vegetables.  During digestion, the body is able to break down most carbohydrates into simple sugars, like glucose.  Eating carbohydrates affects blood sugar levels. Eating a large amount of carbohydrates at a meal will have a larger effect on blood glucose levels than eating a small amount of carbohydrates.  It is important to balance between eating enough carbohydrates to receive the necessary amounts of energy and resultant glucose, and not consuming too much to where blood sugar levels are out of control. 13 of 44 PBRC 2009
  • 14. Eating a healthy diet Meal Plans With this meal plan, the number of grams of carbohydrates that is eaten at each meal or snack is counted to make sure that they are within a certain Carbohydrate range. A meal plan may be very specific, allowing a counting specified amount at each meal or snack, or it may be more general, with a daily carbohydrate total. The exchange system groups each food consumed into one of the following food groups: bread/starches, fruits, vegetables, proteins, milk, and The exchange fats. Each food within a group has very similar system amounts of carbohydrate, fat, protein, and calories, but the amounts of vitamins and minerals may vary. In this plan, the number of items from a food group that is eaten at each meal is counted. There is a designated amount for each group every day. PBRC 2009 14 of 44
  • 15. Eating a healthy diet to keep blood sugar in check: Eat meals and snacks on Researchers recommend that women with gestational diabetes should eat at least three small-to-medium sized meals and two a regular schedule to four snacks every day. throughout the day Eat smaller amounts of It is preferable to eat several small meals every day rather than one large meal. Carbohydrates will increase blood glucose level carbohydrates at each directly, therefore, eating a small amount of carbohydrates all meal through the day will help keep blood sugar from rising too high. Add a nighttime snack to A snack of one or two servings of carbohydrates before bedtime will keep blood sugar at a healthy level during sleep. Some your meal plan healthy examples could include: a piece of fruit, a handful of pretzels, or crackers. PBRC 2009 15 of 44
  • 16. Role of physical activity  Women with gestational diabetes often need regular, moderate physical activity to help control their blood sugar levels by allowing insulin to work better. Keep in mind that it may take 2 to 4 weeks before physical  Examples include: activity has an effect  Walking on blood sugar levels.  Prenatal aerobics classes  Swimming  However, a consultation and approval by a health care provider is needed before beginning any physical activity during pregnancy. 16 of 44 PBRC 2009
  • 17. Role of moderate physical activity How do I do it?  Researchers are uncertain about the exact amount of physical activity required to control blood sugar during gestational diabetes.  The amount that is usually recommended is based on how active an individual was before the pregnancy and whether or not there are any other health concerns.  For some women with GDM, regular physical activity can include walking, swimming, or light running; whereas, for other women only slow walking may be recommended.  A health care provider can offer advice on appropriate activities, and their duration and frequency to assure a healthy pregnancy. PBRC 2009 17 of 44
  • 18. Role of moderate physical activity General Guidelines For Physical Activity Do Don’t Participate in moderate and Get too tired while working out regular physical activity unless prohibited or doing physical activity by a health care provider Choose activities like swimming, Do any activity while lying on your back that don’t require a lot of when you are in your 2nd or 3rd trimester standing or balance of pregnancy Wear loose, light clothing that won’t cause Perform activities in very hot weather excessive sweating or increased body temperature Drink a lot of water before, during, and Perform activities that may bump or hurt after your activity your belly, or that may cause you to lose your balance Eat a healthy diet and gain the Fast (skip meals) or do physical activity right amount of weight when you are hungry Watch your level of exertion Over-exert yourself (Can you talk easily?) PBRC 2009 18 of 44
  • 19. Maintain a healthy weight Overview  Healthy weight gain can refer to your overall weight gain or your weekly rate of weight gain.  Some health care providers focus only on overall gain or only on weekly gain, but some keep track of both types of weight gain. PBRC 2009 19 of 44
  • 20. Maintain a healthy weight Overall Weight Gain Goals Height Weight Status Category Feet Inches A B C D 4 9 92 or less 93-113 114-134 135 or more 4 10 94 or less 95-117 118-138 139 or more 4 11 97 or less 98-120 121-142 143 or more 5 0 100 or less 101-123 124-146 147 or more 5 1 103 or less 104-127 128-150 151 or more 5 2 106 or less 107-131 132-155 156 or more 5 3 109 or less 110-134 135-159 160 or more 5 4 113 or less 114-140 141-165 166 or more 5 5 117 or less 118-144 145-170 171 or more 5 6 121 or less 122-149 150-176 177 or more 5 7 124 or less 125-153 154-181 182 or more 5 8 128 or less 129-157 158-186 187 or more 5 9 131 or less 132-162 163-191 192 or more Your overall 5 10 135 or less 136-166 167-196 197 or more weight gain 5 11 139 or less 140-171 172-202 203 or more goal for the 6 0 142 or less 143-175 176-207 208 or more pregnancy is: PBRC 2009 20 of 44 35-40 30-35 22-27 15-20
  • 21. Maintain a healthy weight Weekly Rate Of Weight Gain Time Frame Expected Weight Gain In the first trimester of pregnancy Three to six pounds for the (the first 3 months) entire three months During the second and third trimester Between ½ and 1 pound each week (the last 6 months) If you gained too much weight early in the Limit weight gain to ¾ of a pound each week pregnancy (3 pounds each month) to help get your blood sugar level under control A weight gain of two pounds or more each week is considered high. PBRC 2009 21 of 44
  • 22. Maintain a healthy weight Things to Keep in Mind 1. A weekly rate of weight gain may go up and down throughout the pregnancy. 2. A physician can assess whether weight gain is appropriate or not. 3. A weight loss can be dangerous during any part of the pregnancy, therefore any weight loss needs to be reported to a health care provider right away. 4. If weight gain slows or stop, and does not increase again after one-to-two weeks, it should be reported to a health care provider immediately. Adjustments in your treatment plan may be necessary. PBRC 2009 22 of 44
  • 23. Maintain a healthy weight Additional tips  Try to get more light or moderate  Use spices and herbs physical activity, if your health care (such as curry, garlic, provider says that it is safe. and parsley) and low-fat or lower calorie sauces  Use the Nutrition Facts labels on food to flavor rice and pasta. packages to make lower-calorie food choices that fit into a healthy meal plan.  Eat smaller meals and have low-calorie snacks  Eat fewer fried foods and “fast” foods. more often, to ensure that your body has a constant glucose supply, and to prevent  Eat healthy foods that fit into your meal yourself from getting very hungry. plan, such as salads with low-fat dressings and broiled or grilled chicken.  Avoid skipping meals or cutting back too much on breakfast or lunch. Eating less  Use less butter and margarine on food, food or skipping meals could make you or don’t use them at all. overly hungry at the next meal, causing you to overeat. PBR9 2009 23 of 44
  • 24. Keep daily records of your diet, physical activity, and glucose levels  Keeping records refers to writing down your blood sugar numbers, physical activities, and everything that you eat and drink in a daily record book.  Recording everything that you eat and drink really means everything that you eat and drink. This refers to bites, nibbles, snacks, second helpings, and all liquids.  It’s easy to forget or underestimate how much snacking you really do. PBRC 2009 24 of 44
  • 25. Keep daily records of your diet, physical activity, and glucose levels  Your health care provider might ask that you keep track of the following:  Blood sugar level  Food  Physical wellness  Physical activity  Weight gain PBRC 2009 25 of 44
  • 26. Keep daily records of your diet, physical activity, and glucose levels  It’s a good idea to follow a schedule for writing in the record book.  This lets you get used to writing in it and helps you to remember to do it.  Daily records help to keep track of how well your treatment plan is working and what, if anything, should be changed.  The information also reveals whether or not you will need insulin, and if so, how much will be needed. PBRC 2009 26 of 44
  • 27. Take insulin and/or other medications as prescribed  Even if you do everything your health care provider recommends to manage your gestational diabetes, you may still need to take insulin during your pregnancy to keep it under control.  The only way to get extra insulin into your body is to inject it under your skin with a needle. PBRC 2009 27 of 44
  • 28. Take insulin and/or other medications as prescribed  You may have to include small amounts of insulin in your treatment plan if:  Your blood sugar level is too high  Your blood sugar level is frequently too high  Your blood sugar level remains high, and you are not gaining much weight even with proper eating habits  You cannot safely add physical activity to your treatment plan PBRC 2009 28 of 44
  • 29. Take insulin and/or other medications as prescribed  Things to know about insulin: 1. If you need to take insulin, it does not mean that you didn’t try hard enough or that you failed at taking care of yourself. 2. Taking insulin does not mean that you have Type 1 diabetes. 3. An increase in the amount or dosage of insulin needed does not mean that your pregnancy is in danger. 4. You may need more insulin if you are under high amounts of stress or if you are sick because your blood sugar level gets higher on its own in these cases. PBRC 2009 29 of 44
  • 30. Take insulin and/or other medications as prescribed  Special instructions for women taking insulin are to:  Follow a regular eating schedule  The timing of insulin shots and of eating meals needs to be correct. Your healthcare provider can tell you when to do both. It is very important not to skip or delay meals and snacks when taking insulin because this can affect your glucose-insulin balance.  Know the symptoms of hypoglycemia  If your blood sugar level drops below 60 at any time, you have hypoglycemia. This can be very dangerous. Hypoglycemia is already common in all women with gestational diabetes, but for women taking insulin for this condition, they are at greater risk. * Before any physical activity is begun, you should test your blood sugar. If it is low, do not PBRC 2009 30 of 44 begin the activity. Eat something and test again to make sure it is higher before beginning.
  • 31. Take insulin and/or other medications as prescribed Why does low blood sugar occur? How might I feel if I have low blood sugar?  Too much exercise  Very hungry  Skipping meals or snacks  Very tired  Shaky or trembling  Delaying meals or snacks  Sweating or clamminess  Nervous  Not eating enough  Confused  Like you’re going to pass out or faint  Too much insulin  Blurred vision * Report any abnormal blood sugar level to your health care provider right away, in case a change in your treatment plan is needed. PBRC 2009 31 of 44
  • 32. Will GDM hurt my baby?  Most women with gestational diabetes give birth to healthy babies; this is especially true for women who have kept their blood sugar under control, maintained a healthy diet, engaged in regular, moderate physical activity, and had a healthy weight throughout the pregnancy.  In some cases, however, the condition can affect the pregnancy. PBRC 2009 32 of 44
  • 33. Gestational Diabetes Mellitus Associated Conditions Macrosomia In this condition, the baby’s body is larger than normal. Large-bodied babies may be injured during natural delivery through the vagina, so the baby may need to be delivered through cesarean section. Hypoglycemia In this condition, the baby’s blood glucose is too low. Breastfeeding may need to be started right away to get more glucose into the baby’s system. If breastfeeding is not possible, then the baby may need to get glucose put directly into the blood through a thin, plastic tube in his or her arm. Jaundice In this condition ,the baby’s skin turns yellowish. The white parts of the eye may also change color slightly. If treated, this is not a serious problem. Respiratory In this condition, the baby has trouble breathing. The baby may need oxygen or Distress other help breathing if he or she has this condition. Syndrome (RDS) Low Calcium and In this condition, spasms in the hands and feet, or twitching and cramping of Magnesium Levels muscles can occur. The condition can be treated through supplementation with in Baby’s Blood magnesium and calcium supplements. Keep in mind that just because you have gestational diabetes, it does PBRCmean that these problems will occur. not 2009 33 of 44
  • 34. Could GDM hurt my baby in other ways?  Gestational diabetes usually does not cause birth defects or deformities.  Most developmental or physical defects happen during the first trimester of pregnancy, between the 1st and 8th week, and gestational diabetes typically develops around the 24th week of pregnancy.  Therefore, women with gestational diabetes typically have normal blood sugar levels during the first trimester, allowing the body and body systems of the fetus to develop normally. PBRC 2009 34 of 44
  • 35. Could GDM hurt my baby in other ways?  The fact that you have gestational diabetes will not cause diabetes in your baby.  However, your child will be at a higher risk for developing type 2 diabetes in adulthood and may get it at a younger age (younger than 30).  As your child grows, taking steps such as: eating a healthy diet, maintaining a healthy weight, and getting regular, moderate physical activity can help to reduce his or her risk.  Macrosomic, or large-bodied babies are at higher risk for childhood and adult obesity. PBRC 2009 35 of 44
  • 36. Things to keep in mind about delivery If you have gestational diabetes Blood Sugar and Keeping blood sugar levels under control during labor and delivery is vital for both Insulin Balance you and your baby’s health. If you did not have to take insulin during the pregnancy, then you won’t need it during labor or delivery; however, if you did have to take insulin during pregnancy, then you may receive an insulin shot when labor begins or during labor. Early Delivery Gestational diabetes puts women at higher risk for a condition known as preeclampsia late in pregnancy. Preeclampsia is a condition associated with sudden blood pressure increases, which can be quite serious. Unfortunately, the only cure to preeclampsia is delivery of the baby, but delivery may not be the best option for your health or for the health of your baby. Your health care provider will keep you under close watch if this condition develops, determining whether early delivery is safe and needed. Cesarean This is a type of delivery used to deliver the baby, as opposed to natural delivery Delivery through the vagina. Cesarean delivery is also referred to as a cesarean section, or “C” section. Simply having gestational diabetes is not reason alone to have a C section, but your health care provider may have other reasons for choosing this option, such as changes in your health or your baby’s health during delivery. PBRC 2009 36 of 44
  • 37. Will I have diabetes after having my baby?  Shortly after the baby is born, the placenta is “delivered.”  Since the placenta is what was causing the insulin resistance, when it is gone, gestational diabetes usually resolves as well.  Just by having had gestational diabetes, you have a 40% higher chance of developing type 2 diabetes later in life than women who did not have the condition during pregnancy.  Keeping your weight within a healthy range and keeping up regular, moderate physical activity after your baby is born can help lower your risk for developing type 2 diabetes. PBRC 2009 37 of 44
  • 38. What should I do after delivery?  Six weeks after your baby is born, you should have a blood test to find If your category is… You should… out whether your blood sugar level Get checked for is back to normal. Normal diabetes every 3 years Get checked for  Based on the results you will fall diabetes every year, into one of the three categories: Impaired Glucose and talk with your health care provider to Tolerance learn about ways to lower your risk for developing diabetes. Work with your health Diabetic care provider in setting up a treatment plan for your diabetes. PBRC 2009 38 of 44
  • 39. Importance of checking often  Getting checked for diabetes is important because Type 2 diabetes shows few symptoms.  The only way to know for sure is to have a blood test that reveals a higher-than-normal blood sugar level.  If you notice any of these things, you should tell your health care provider right away:  Being very thirsty  Urinating often  Feeling constantly or overly tired  Losing weight quickly and/or without reason PBRC 2009 39 of 44
  • 40. Will I develop Type 2 diabetes in the future? There are certain traits which increase the chances: 1. You developed gestational diabetes before your 24th week of pregnancy. 2. Your blood sugar level during pregnancy was consistently on the high end of the healthy range. 3. Your blood sugar levels after the baby was born were higher-than-average, according to your health care provider. 4. You are in the impaired glucose tolerance category. 5. You are obese, according to your health care provider. 6. You have diabetes in your family. 7. You belong to a high-risk ethnic group (Hispanic, African American, Native American, South or East Asian, Pacific Islander, Indigenous Australian). 8. You have had gestational diabetes with other pregnancies. With one or more of these traits, you should talk to your doctor about Type PBRC 2009 2 diabetes. 40 of 44
  • 41. Should I breastfeed having gestational diabetes?  Yes, women with gestational diabetes should breastfeed their babies, if possible.  Breastfeeding is not only beneficial to the baby, but it is also beneficial to the mother.  Breastfeeding allows the body to use extra calories stored during pregnancy, allowing for weight loss.  A weight loss after having the baby not only enhances overall health, but also helps to reduce the risk of developing type 2 diabetes later in life.  Breastfeeding is also believed to help lower fasting blood glucose levels in mothers. PBRC 2009 41 of 44
  • 42. Heli J. Roy, PhD, RD Shanna Lundy, BS Division of Education Phillip Brantley, PhD, Director Pennington Biomedical Research Center Steven Heymsfield, MD, Executive Director Division of Education
  • 43. About Our Company  Pennington Biomedical Research Center  VISION  Our vision is to lead the world in eliminating chronic diseases.  MISSION  Our mission is to discover the triggers of chronic diseases through innovative research that improves human health across the lifespan. We are helping people live Well Beyond the Expected.  The Pennington Center has several research areas, including:  Clinical Obesity Research  Experimental Obesity  Functional Foods  Health and Performance Enhancement  Nutrition and Chronic Diseases  Nutrition and the Brain  Dementia, Alzheimer’s and healthy aging  Diet, exercise, weight loss and weight loss maintenance  The research fostered in these areas can have a profound impact on healthy living and on the prevention of common chronic diseases, such as heart disease, cancer, diabetes, hypertension and osteoporosis.  The Division of Education provides education and information to the scientific community and the public about research findings, training programs and research areas, and coordinates educational events for the public on various health issues.  We invite people of all ages and backgrounds to participate in the exciting research studies being conducted at the Pennington Center in Baton Rouge, Louisiana. If you would like to take part, visit the clinical trials web page at www.pbrc.edu or call (225) 763-3000. PBRC 2009 43 of 44
  • 44. Sites  All diabetes-related information is from the National Institute of Child Health and Human Development. Available at: http://www.nichd.nih.gov/publications/pubs/gdm/index.htm PBRC 2006 44 of 44